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Effects of human fetal liver extract on the growth of HL-60 cells.

Two kinds of HL-60 cell growth suppressor present in human fetal liver were studied. One is the already known arginase, which showed nonspecific suppression on the growth of HL-60 cells and human granulocyte-macrophage progenitors (CFU-GM), and the other, a new species of suppressor with the characteristics of lower molecular weight (less than 10,000 daltons), shows preferential suppression on HL-60 cell growth, but less effect on the growth of CFU-GM.

Arginase↗