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At least 451 records · Page 25Linked to original sources
PubMed1982

Steroid myopathy. Insidious cause of muscle weakness.

Steroids are so commonly prescribed for so many conditions that physicians tend to become somewhat cavalier in their use. With drug therapy of any type, however, this tendency can lead to trouble. Steroid myopathy, as occurs in Cushing's syndrome. Can develop with steroid therapy and can cause irreversible atrophy if not detected and treated early.

Adrenal Cortex Hormones↗
PubMed2006

An unusual cause of muscle weakness: a case report.

Thyrotoxic hypokalemic periodic paralysis (THPP) has been reported earlier in the Asian population. However, it is now becoming increasingly common in the Western countries as well. Thus, its in-depth knowledge is a must for every physician so that this diagnosis is not overlooked in any case presenting with extremity weakness and paralysis, especially considering its reversible nature. We present an interesting case of THPP in a Vietnamese patient presenting with bilateral lower extremity weakness and extremely low serum potassium levels. We also present a comprehensive discussion and review of literature related to THPP, which would be helpful for the internists to diagnose and appropriately manage this disease.

Adrenergic beta-Antagonists↗
PubMed2002

A case of weak muscles.

BACKGROUND: Gut involvement in inflammatory myositis is rare but causes significant morbidity and mortality. CASE REPORT: A case of eosinophilic gastroenteritis and polymyositis occurring in the same patient is described. The interface of visceral and striated muscle involvement is discussed. The pathophysiology of eosinophilic gastroenteritis and the spectrum of gastrointestinal involvement in inflammatory myositis are also discussed. RESULTS: Both gastrointestinal and skeletal muscle symptoms improved with immunosuppression, suggesting a possible common underlying mechanism.

Alpha-Globulins↗
PubMed1988

Respiratory muscle weakness associated with cerebellar atrophy.

Transdiaphragmatic pressures were measured in 3 patients with cerebellar atrophy. Recordings were made during 3 types of voluntary maneuver--maximal sniffs, full inspirations, and maximal static inspiratory efforts, and during bilateral supramaximal phrenic nerve stimulation at 1 Hz. Although diaphragmatic weakness was demonstrated during the voluntary maneuvers, transdiaphragmatic pressures recorded during phrenic nerve stimulation were normal. These findings indicate that diaphragmatic dysfunction, probably caused by ataxia during voluntary maneuvers, may occur in association with cerebellar atrophy. In the presence of diaphragmatic weakness, normal values of transdiaphragmatic pressure during phrenic nerve stimulation may suggest an upper motor neuron lesion affecting the diaphragm.

Adult↗
PubMed1977

Serum creatine phosphokinase levels and prednisone treated muscle weakness.

Evidence is cited from the literature and from personal experience with the "inflammatory" form of facioscapulohumeral syndrome that the creatine phosphokinase reduction occurring during pharmacologic treatment of various neuromuscular diseases does not necessarily imply therapeutic benefit.

Adolescent↗