Statistics on occupational contact dermatitis from (meth)acrylates in dental personnel.
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Cross reactions are described between particular aromatic amines, between phenylenediamine ortho-, meta- and para-isomers and between aromatic amines and related substances. Moreover, the sensitization pattern and some sources of primary sensitivity to aromatic amines are discussed.
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Eight workers handling fiberglass coated with uncured epoxy resin, out of a population of approximately 130 workers, developed dermatitis of their hands and forearms. Four also had involvement of the head and neck. Epicutaneous testing established the presence of contact allergy to epoxy resin in six, and one worker had continuous sensitivity to cresylglycidyl ether. Workers handling the coated material after it had been heat-cured were not affected, even if they had had problems with dermatitis while handling the uncured coated fiber.
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Immunological and functional studies are performed on workers engaged in the production of plastics, artificial fibres and dyes, in view of clarifying some mechanisms in the evolution of the contact dermatitis and the related with it early changes. The study establishes increased values of IgA and IgG in workers in contact with irritating substances and increased values of IgG in workers in contact with sensitizing substances. In the latter is registered a decrease in the active and the total rosettes. The functional investigations, performed on 292 workers point out to no essential deviations in pH values in the limits of the physiological variability. The alkaline resistance of the skin is decreased in 51% of the examined, who are in contact with irritating substances and in 29.7% exposed mainly to sensitizing substances.