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The hard palate.

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Adult↗

A new method for strengthening palatal closure defects of the hard palate.

Closure of minor defects in the hard palate can be done with local flaps. There is often a risk of perforation of the reconstructed area. In the case reported this complication was obvious due to a large, thin, flap-covered area. In strengthening the reconstruction fascia lata and Surgicel was used. The postoperative result was excellent and the rehabilitation of the patient was without complications.

Carcinoma, Squamous Cell↗

Results of radiation therapy in oral squamous cell carcinoma.

Between 1967 and 1976, 153 patients with previously untreated squamous cell carcinoma of the oral cavity received radiation therapy, either interstitial irradiation or external beam therapy (usually 60Co). Five-year survival rates without evidence of disease were 90 per cent in stage I, 50 per cent in stage II, 21.3 per cent in stage III, and 2.3 per cent in stage IV. Thirty-one patients with clinically non-metastatic neck nodes not prophylactically irradiated had a high incidence of later metastatic neck disease compared with patients who received elective irradiation of the neck.

Adult↗

Metastatic tumors in the sellar and parasellar regions: clinical review of four cases.

Metastatic tumors in the sellar and parasellar regions are uncommon and rarely detected in clinical practice. We present four cases of sellar and parasellar metastatic tumors, which metastasized from distant organ in one case and extended directly from adjacent structures in three. Common presenting symptoms were cranial neuropathies, headache and facial pain. Invasion into the cavernous sinus was noted in all cases. We report rare cases of sellar and parasellar metastases. Also, we should consider the possibility of metastasis in these regions for patients who showed the above clinical presentations in systemic cancer patients. In extensive diseases, transient symptomatic relief could be obtained by direct surgical management, even in restricted degree.

Adenocarcinoma↗

Extraskeletal Ewing's sarcoma of the hard palate.

Extraskeletal Ewing's sarcoma (EES) is a rare soft tissue tumor morphologically indistinguishable from the more common Ewing's sarcoma of bone. We report a case of EES arising in the hard palate of 34-yr-old male patient. Microscopically, the monotonous small round cells without neuronal differentiation showed membranous positive immunoreactivity for MIC2/CD99 and vimentin. Ultrastructurally, the tumor cells showed a few intracytoplasmic organelles without evidence of neurosecretory granules or neurofilaments. The EWS-FLI1 chimeric gene was identified using the nested reverse transcriptase-polymerase chain reaction.

12E7 Antigen↗

[Application of prosthetic replacement for bilateral maxillectomy defect].

A 59-year-old woman with large hard palate cancer underwent surgical resection. We constructed a maxillary prosthesis to be connected to the patient's mandibular denture. Bilateral maxillectomy resulted in total loss of the hard palate and bilateral alveolar and partial loss of the soft palate. A obturator prosthesis was prepared beforehand to fit the surgical cavity. The patient recovered functional speech and swallowing at a relatively early stage, achieving satisfactory cosmetic results.

Carcinoma, Squamous Cell↗