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PubMedDate not supplied

[Ocular cysticercosis, typical forms and treatment].

We report two personal cases of intra ocular cysticercosis typical by their sub retinal and intra vitreous localization. After a short review of epidemiology and biological diagnostic we propose a treatment which associates a medical part with Praziquantel, killing the larva and a surgical part with pars plana vitrectomy allowing the control of the inflammation, contemporary of the larva's death and the intra-vitreous cysticercosis extraction.

Adult↗
PubMed1990

Immunodiagnosis of human cysticercosis in cerebrospinal fluid. Antigens from murine Taenia crassiceps cysticerci effectively substitute those from porcine Taenia solium.

Tapeworm antigens from Taenia crassiceps performed as well as those antigens from Taenia solium in an enzyme-linked immunosorbent assay for the detection of Cysticercus antibodies in 96 cerebrospinal fluid samples from patients with neurocysticercosis and in 96 CSF samples from patients with other varied neurological ailments. Thus, this manageable murine model of experimental cysticercosis solved the problem of antigen supply for clinical and epidemiological applications, and it provided an immediate means of abundant production of antigens for the wide distribution and standardization of immunodiagnostic tests for cysticercosis.

Animals↗
PubMedDate not supplied

[5 cases of cysticercosis in Rwanda].

Five cases of cysticercosis are reported. They were diagnosed by microscopic examination of the sub-cutaneous nodules in which T. Solium larvae were found. Results of the treatment by Praziquantel are reported, with regard to the symptomatology of the patients after one year of observation. Necrosis of cysticerci larvae few month after starting the treatment was observed in three cases by microscopical anatomy test. Three doses of Praziquantel of 20 mg/kg at four hours of interval are efficient against sub-cutaneous and muscular cysticercosis. Such a treatment presents the advantage very important in some rural zones in Africa, of a single dose in one day.

Adult↗
PubMedDate not supplied

Fine needle aspiration cytology of subcutaneous cysticercosis of the breast. Case report and pathogenic discussion.

A case of subcutaneous cysticercosis of the breast diagnosed by fine needle aspiration cytology is reported. The cytologic preparations showed the presence of many inflammatory cells mixed with spiked spherules resembling the rambutan tropical fruit. These spherules arose from the degenerated integument of the parasite found in the histologically excised cyst. They are suggestive of the presence of an encysted flat worm, but are not specific for cysticercosis, whose identification is based on the study of the cephalic extremity of the parasite.

Adult↗
PubMed1989

[Clinico-anatomic characteristics of cysticercosis of the brain].

Polymorphism clinical signs is typical of the brain cysticercosis. This is explained by different location of parasites and various complications as adhesive arachnoiditis, internal hydrocephaly, and demolition caused by cysticercosis-related thromboarteritis.

Adult↗
PubMed1988

[Racemous cysticercosis of the cauda equina and cystic arachnoiditis. Apropos of 2 cases].

Central nervous system infection by the larval form of the pork tapeworm, taenia solium is a major public health problem in view of its prevalence. The high incidence of neurocysticercosis in Reunion Island has been precised by computerized tomography and Elisa test. Spinal involvement is an uncommon form of cysticercosis, occurring with a frequency of less than 1% in large series. The types of involvement that are most common are subarachnoid cysts which appear as intradural extramedullary masses and meningeal reaction with appearance of arachnoiditis at myelography. Intramedullary involvement is less frequent. Epidural and subpial masses have been reported very rarely. The authors report the two first cases of spinal cysticercosis in Reunion Island which are both extramedullary leptomeningeal forms. A radicular syndrome was present in both cases; incontinence and sacral hemihypoesthesia in one case. Myelography showed lumbosacral arachnoid cysts. Immunodiagnostic tests were positive in blood and C.S.F. in the two cases. Laminectomy was performed and the arachnoid membrane appeared opaque and thickened; the cysts were removed. Microscopically the cystic wall had a thin and curved cuticle, no scolex was found. Treatment was completed with the anti-helminthic agent Praziquantel. Full recovery was observed in one case. In the other case low back pain spread out to the lower extremities with a non radicular distribution and was associated with lumbosacral spinal fibrosis.

Adult↗
PubMed1986

[Counterimmunoelectrophoresis in the serologic diagnosis of cysticercosis in cattle].

Over the years 1983 to 1984 two-hundred and sixty-five bulls were examined during mass occurrence of bovine cysticercosis in one farm; out of this number 67 animals (25.3%) were confirmed autopsically as infected with cysticercosis. Counterimmunoelectrophoresis was used to examine the serum of slaughtered animals by help of two antigens--Taenia saginata and Taenia crassiceps. With T. saginata the sensitivity amounted to 44.8% and the specificity to 86.4%, with T. crassiceps to 28.3% and to 89.9%.

Animals↗
PubMed1988

Taenia solium taeniasis and cysticercosis in a Mexican village.

One hundred and twenty-four persons, nearly the entire population of a rural village in Hidalgo State, were screened for intestinal parasites and clinical or serologic (ELISA) evidence of Taenia solium cysticercosis. Heads of households were questioned about dietary and other practices that might lead to pork tapeworm transmission, and soil samples were examined for helminth eggs. Twenty-five percent of local pigs had cysticerci visible by examination of the undersurface of their tongues. Four persons passed taeniid eggs, 7 were seropositive, and 10 gave medical histories suggestive of neurodysticercosis. Most seropositive persons were not symptomatic and the reverse was also true. The clustered distribution of infected pigs, tapeworm carriers, and persons with serologic or clinical evidence of cysticercosis suggested intrahousehold transmission. Dietary and sanitary practices were generally optimal for transmission of pork tapeworm. No cattle were kept in the village and beef was rarely eaten. This preliminary report attempts to characterize T. solium transmission in communities with endemic disease in rural Mexico and illustrates some of the methodological problems faced by epidemiologists who study this disease.

Adult↗
PubMedDate not supplied

[A case of cerebral cysticercosis treated with praziquantel in the postoperative period].

A 51-year-old man with cerebellar signs and raised intracranial pressure had negative indirect and serological tests for cysticercosis. During operation cysticerci were removed from the cisterna magna, fourth ventricle and aqueduct. Histological examination confirmed the diagnosis of cysticercosis. After operation the condition of the patient deteriorated consciousness disturbances, involuntary movements of the left upper extremity and paraparesis appeared. Only after treatment with Praziquantel with simultaneous administration of oedema-reducing agents nearly complete regression of neurological manifestations was achieved.

Cerebral Ventricles↗
PubMed1988

Intraparenchymal cerebral cysticercosis in children: diagnosis and treatment.

Cerebral cysticercosis is being diagnosed with increasing frequency in children in the United States. A total of 52 patients with intraparenchymal cerebral cysticercosis, 21 months to 20 years of age, were observed for 2 to 72 months. Actively inflamed acute lesions, with or without coexisting chronic calcified lesions, were seen in 42 patients. Solitary lesions were seen in 39 patients, multiple lesions in 13. Chronic inactive calcified lesions were seen in ten children. A total of 51 patients had seizures that were either partial or partial with secondary generalization. Patients were treated with anticonvulsants. Praziquantel was not used. All active lesions resolved completely or with punctate calcification in 2 to 9 months, according to radiographic findings. Seizures were easily controlled. Patients were gradually weaned from anticonvulsants and in 60% no seizures recurred. Prognosis was generally good. Characteristics of the CT scans are detailed.

Acute Disease↗
PubMed1987

Seventy black epileptics. Cysticercosis, computed tomography and electro-encephalography.

Computed tomography (CT) in a group of 70 black patients with epilepsy showed cerebral cysticercosis in 30%, with signs of activity in 12.9%. The possibility of effective treatment in active cysticercosis makes CT an important investigation of epilepsy in this population. Electro-encephalography is of some practical value in patients in whom CT is negative.

Adolescent↗
PubMed1987

[Association of cerebral cysticercosis and multifocal glioma. Discussion of interactions].

Diagnosis in a case of cerebral parenchyma cysticercosis was based on conventional arguments described in the literature. The patient died after progression of the disease over 6 months, despite two courses of Praziquantel. Results of neuropathologic examination confirmed diagnosis of cysticercosis and the discovery of a multifocal astrocytic tumor involving mainly the periventricular regions. Possible interactions between parasitic infection and glioma are discussed but it is difficult to determine the precise role played by the parasitosis in the evolution of the tumor, the hypothesis of a simple coincidence being most likely. Periventricular images of an inflammatory nature observed after PZQ treatment should not be accepted unreservedly, and when an unfavorable course is apparent the periventricular histopathologic lesions should be compared with results of CT scan imaging qualified as periventricular in origin.

Brain Diseases↗
PubMedDate not supplied

[Neuropathologic analysis of 8 undiagnosed cases of cerebral cysticercosis].

The presented material comprised 17 cases observed in four Warsaw hospitals in a period of 20 years. Nine patients with the pseudotumour syndrome were diagnosed correctly and referred to neurosurgical services. The remaining eight cases died in neurological hospital departments with the following clinical diagnoses: cerebral stroke 3, subarachnoid haemorrhage 1, comatose state preceded by dementia 1, chronic meningoencephalitis 1, status epilepticus 2 cases postmortem investigations demonstrated cerebral cysticercosis in all cases. In four patients with predominant symptoms of cerebrovascular disease lesions were found of the type of residual vasculitis cysticercosa, the sequelae of which might have caused secondary complications independent of concomitant arteriosclerosis. Dementia appeared in a patient with huge hydrocephalus consequent to numerous cysticerci. The patient with the diagnosis of meningoencephalitis had an inflammatory reaction of the ependyma and meninges caused by a cysticercus floating in the IV ventricle. Of the patients dying in status epilepticus attention is called to a 6-year-old girl with a solitary cysticercus localised subcortically in the motor area. The authors suggest that the possibility of cysticercosis should be kept in mind, despite its rarity, in cases with a not completely clear clinical manifestations of cerebrovascular disease, chronic meningoencephalitis and epilepsy or dementia.

Aged↗
PubMed1986

Cerebral cysticercosis in rural dogs.

Cysticercus cellulosae was found in the brain of three (2.5%) out of 120 rural dogs investigated. The cysts were located in the ventricle, cerebral cortex and subarachnoid spaces. Two (1.7%) of the 120 dogs had dumb rabies and this was confirmed by biological tests. One of these dogs had both cysticerci and Negri bodies in the brain. Apart from locomotor imbalance no other typical clinical signs of rabies were observed. Dumb rabies and cysticerci in dogs being sold to people in rural communities pose potential public health hazards. In areas where dog flesh is used as a source of food, human cysticercosis may occur, and the danger of human rabies must not be overlooked. Environmental sanitation and public education are necessary in order to reduce the incidence of cysticercosis in rural dogs.

Animals↗
PubMed1985

Heterogeneity of humoral immune components in human cysticercosis.

Twelve Taenia solium cysticerci, obtained from several human organs, were examined by immunofluorescence for IgG, IgM, IgA, IgE and C3b on their surfaces. Anti-cysticercus antibodies of the 4 classes of immunoglobulins were looked for in the cerebrospinal fluid of most neurologic patients, in the intraocular humors of a patient with eye cysticercosis, and in the serum of some other patients. The morphological appearance of the parasites as well as the clinical features of the patients were recorded. The distribution of components was heterogeneous among the different parasite surfaces. IgG was the most frequent, followed by IgA, IgM, C3b and IgE. No correlation was found between the presence of these molecules and signs of damage in the cysticerci, or with the classes of immunoglobulins found as anti-cysticercus antibodies. Possible explanations of these findings as well as the implications of heterogeneity in cysticercosis are discussed.

Adolescent↗
PubMed1985

The computed tomographic spectrum of cerebral cysticercosis.

A review of the disease cerebral cysticercosis is presented. The pathogenesis, symptomatology, diagnosis, and treatment of this disease is discussed with an emphasis on the role of computed tomography in the diagnosis of cerebral cysticercosis.

Adolescent↗
PubMedDate not supplied

Optical-chiasmatic region epidermoid with a suprasellar and prepontina region cysticercosis.

The Authors report a case of epidermoid in the optical-chiasmatic region associated with a cysticercosis in the suprasellar and prepontal region. The patient was surgically treated with success: a bilobate cystic formation with ramifications adherent to the carotid siphon was found in front of optic nerves. Opening the arachnoid between the left optic nerve and carotid, a dysembriogenetic cystic formation was observed. Adherent to it there was the wall of a second parasitic cystic formation (probably cysticercosis) from which some small cysts slid away. After a review of the literature the Authors point out both the casual association of the two pathologies and the utility of C.T. scan in the diagnostic process of the above mentioned lesions.

Brain Diseases↗