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The proportion of various types of congenital color vision defects.

One hundred and three color vision defective subjects were screened from 3456 middle school students with pseudoisochromatic plate test. One hundred subjects out of them were further examined with a test battery including Panel D-15 and FM 100-hue test and Neitz anomaloscope test. It was found that there were 21 protanopes (P), 3 extremely protanomalous (EPA), 13 protanomalous (PA), 25 deutenopes (D), 5 extremely deuteranomalous (EDA), 28 deuteranomalous (DA), 6 unclassified subjects in our investigation. The proportion of various types of congenital color vision defects was P:EPA:PA:D:EDA:DA = 1.00:0.14:0.62:1.19:0.24:1.33.

Adolescent↗

[Study on color misnaming among the congenital color vision anomalous--Part 1. The tendency in color misnomer].

I report the hue and the color misnomers of 16 subjects with protanopia (color misnomers: 500) and 66 subjects of deutanopia (color misnomers: 2,056), and the color misnomers used by over 10 subjects each and their numbers. Green was the most frequent misnomer, followed by grey, yellow-green, purple, and brown. The deutanopia patients frequently used the Munsell color notation RP for grey. Many of the subjects who misnamed 11 times or more failed the Panel D-15 test. They were diagnosed as having strong color anomaly in the Ohkuma isochromatic plates and in the Tokyo Medical College isochromatic plates. The misnomers were most frequent among the neighboring hues. The severer the anomaly, the further the separation from the test color, and then the misnomers crossed the achromatic confusion line. Judging from the misnomer variation, the color sense of color anomaly does not necessarily seem to be constant. Moreover, liaison was noticed among red, brown, green, or occasionally purple in terms of misnaming pattern. Grey and pink were also linked in misnaming. Lightness was considered to play a strong role in these confusions.

Adolescent↗

Reversible colour vision defects in obstructive jaundice.

The ocular function of 14 non-alcoholic, high icteric patients with recent occlusion of the common bile duct and 3 patients with viral hepatitis with a cholestatic pattern was studied. By means of a colour vision test panel including the Farnsworth-Munsell 100-hue test, 12 patients were initially classified as colour defective with a pattern of acquired colour vision deficiency (ACVD), predominantly of a tritan type. Visual acuity, visual field, slit lamp microscopy, intraocular pressure, ophthalmoscopy and tear secretion tests were normal, and all patients had normal levels of serum vitamin A. Retesting of 4 initially colour defective patients after disappearance of the obstructive jaundice showed a complete normalisation of the ACVD's. It is concluded, that the colour perception in patients with obstructive jaundice is related to the serum bilirubin level, and not to a deficiency of vitamin A.

Adult↗

Nomograms for the assessment of Farnsworth-Munsell 100-hue test scores.

Although the Farnsworth-Munsell 100-hue test is a sensitive means of evaluating congenital and acquired color vision deficiencies, using the data it provides involves complex calculations. We have developed two nomograms that permit the clinician to determine quickly and easily whether a given score is normal for the patient's age and whether the difference between fellow eyes is within the normal range.

Adult↗

Autosomal dominantly inherited macular dystrophy with preferential short-wavelength sensitive cone involvement.

We found an apparently inherited tritan-like color vision defect in five members of a family, spanning three generations. The defect was associated with mild macular pigmentary changes, poor foveolar reflexes, or slightly reduced visual acuity in four of the affected individuals. The inheritance pattern appeared to be autosomal dominant. Results of various color vision tests indicated preferential involvement of the short-wavelength sensitive cone system, with relative preservation of the middle- and long-wavelength sensitive cone systems. Both anomaloscope testing with larger (8-degree) fields and short-wavelength sensitive electroretinography indicated some short-wavelength sensitive cone system involvement beyond the central macula in the three affected individuals on whom testing was performed. The condition appeared to be a familial macular dystrophy with preferential short-wavelength sensitive cone involvement. The abnormal macular findings and mild reduction in visual acuity distinguish this condition from congenital tritanopia; the normal optic disks distinguish it from autosomal dominant optic atrophy.

Adolescent↗

[Color vision in glaucoma].

The author presents an account on the results of examinations of colour vision in patients with ocular hypertension and open angle glaucoma using three tests according to Farnsworth-Munsell (100 Hue test, Roth's 28 Hue test, Lanthony's desaturated panel D-15). He proves significant deterioration of colour differentiation in groups of patients with glaucoma and ocular hypertension as compared with a reference group and within the group. Although there is deterioration of colour differentiation in the entire spectrum, disorders in the blue-yellow and blue-green area predominate.

Adult↗

The effect of restricted viewing time on the performance of colour defectives using the City University Colour Vision Test.

The effect of restricting viewing time to 3.75 ms on the performance of seven red/green colour defectives is studied using the City University Colour Vision Test. One further subject who was screened as colour-defective but not classified on the City plates was studied in the same way and results for this subject are presented separately. The results are compared to those for normal observers who exhibit a tritan-classified defect when viewing time is restricted to 3.75 ms.

Color Perception Tests↗

Color vision in albino subjects.

Color vision testing was performed on a group of ten black tyrosinase-positive albino patients and a group of normal subjects. Testing was accomplished by means of a Farnsworth-Munsell (F-M) 100-hue test and Nagel anomaloscope. As a group, the albino patients showed an increase in number of errors scored on the FM-100 hue test, without any specific axis in the majority of cases. Results on the Nagel anomaloscope showed a 'widening' into the red end of the Rayleigh equation. A possible explanation for this apparent widening is discussed, which emphasizes anticipated results of matching ranges obtained on extrafoveal cones.

Adolescent↗

[Evaluation of the desaturated Panel D-15. II: Comparison between the desaturated Panel D-15 and Farnsworth 100-hue tests].

The color vision was examined in 319 subjects in a comparative manner by means of the desatured Panel D-15 and Farnsworth 100-hue test used as reference test. The results expressed by scoring, were as follows: 1) a strong correlation (r = 0.80) was evidenced between the 2 tests; 2) the probable scores of the desaturated Panel D-15 were predicted from the 100-hue scores, by means of a suitable regression equation; thus allowing the calculation of norms of the desaturated Panel D-15 by reference to the well-established norms according to age of the 100-hue test; 3) the normal or pathological character of the scores of the desaturated Panel D-15 was infered from these norms, and was in good agreement with the scores of 100-hue test (K = 0.68); 4) the normal or pathological character of the qualitative patterns of the desaturated Panel D-15 was also infered from the scores; so: the minor errors were normal from 30 years old patients; a single diametral error is normal; 3 or 4 diametral errors are normal from 65 years old patients.

Adolescent↗

An averaging method for the interpretation of the Farnsworth-Munsell 100-Hue Test--I. Congenital colour vision defects.

A method is described for identifying polarity in Farnsworth-Munsell 100-Hue test data. The method is facilitated by the use of a micro-computer and involves the plotting of "averaged" scores for each cap of the test. Results are presented for 30 protanopes, 30 deuteranopes, 1 tritanope and 2 typical rod monochromats. Analysis of the results shows that the proposed technique is compatible with standard methods of interpreting 100-Hue plots and is suitable to use when error scores are high and when polarity is difficult to interpret.

Adolescent↗

Color vision testing of healthcare personnel.

The purpose of the study was to identify and describe color vision testing of healthcare personnel who do glucose monitoring within a hospital. The subjects were 359 members of a nursing staff. Data were collected from nurses participating in a certification program for blood glucose monitoring. The lshihara plates were used to screen for a color vision deficiency. The results offered no evidence that screening of staff provided any benefit for patient care.

Blood Glucose Self-Monitoring↗

Long wavelength pass filters designed for the management of color vision deficiencies.

This study reports on the effectiveness of long wavelength pass filters dispensed as tinted spectacles as an aid for individuals with congenital red-green color vision deficiencies. The effectiveness of the filters was evaluated by the performance on a series of clinical color vision tests and a questionnaire after the subjects had tried the lenses for 1 week. The lenses improved performance on color vision tests that required discrimination between large color differences, particularly between red and green hues. However, performance was degraded on tests which required fine color discrimination or used colors that were located parallel to the tritan confusion axis. The improved performance on certain tests was primarily based on brightness artificats induced by the filters, whereas the degraded performance on the other tests was due to the absorption of short- to midwavelength light by the filters. A slight majority (56%) of the subjects rated the filters as being moderate to highly effective in improving their color discrimination. Nevertheless, only 17% were interested in actually purchasing a pair. Common reasons for rejecting the filters were the color distortions produced by the red filters and fewer colors were actually perceived when wearing the filters.

Adolescent↗

New method based on random luminance masking for measuring isochromatic zones using high resolution colour displays.

A new method of measuring normal hue discrimination ellipses and dichromatic zones using a high resolution colour monitor is described. The test involves the detection of chromatic bars on a grey background (x = 0.305, y = 0.323) having a luminance of 34 cd m-2. Elements of the background matrix of square checks are varied randomly in luminance in space and time to provide random luminance masking (RLM) which compensates for differences in the relative luminous efficiency of different observers. The measurement technique provides a rapid and comprehensive colour vision test. Typical results are presented for normal trichromats, protanopes and deuteranopes without RLM and with the RLM set of 25%. The size of the discrimination ellipse in normal observers is the same in both viewing conditions, but the use of the RLM technique reveals the extent of the isochromatic zones in colour deficient observers.

Color Perception Tests↗

[Mass screening of blue color vision in divers with the desaturated Lanthony-15-Hue Test].

We tested 1002 persons, 572 divers (including 38 who had diving accidents) and 430 nondivers, for defects of the blue-sensitive system during the years 1988 and 1989. Recent research has shown functional disorders of color vision in divers, linked to previously described alterations of the retinal capillary system and pigment epithelium. The desaturated Lanthony-15-HUE test was used as a screening method. No defect of the blue-sensitive system was found, either in divers or in nondivers. Our results are similar to those of other researchers. One exception was that we found no correlation between age and error score. We found no evidence for retinal damage caused by diving.

Adult↗

Autosomal recessive incomplete achromatopsia with protan luminosity function.

A unique form of dichromatic color vision is described in a family with incomplete achromatopsia. In 1966, incomplete achromatopsia was diagnosed in 4 of 14 children of a consanguineous marriage. The 4 affected had best visual acuities of 6/60 or 6/180, pendular nystagmus, and aversion to bright lights. The ERG showed minimal photopic responses. No abnormality of rod function was present. There was a severe color vision defect. In 1976, one of the patients returned for further color testing. Color tests included measurement of the luminous efficiency function using heterochromatic flicker photometry and colorimetric evaluation. The luminous efficiency function resembled that of the protanope. From the colorimetric measurements, we conclude that the patient has a unique form of dichromatic color vision mediated by two visual photopigments: the normal MWS cone photopigment and a photopigment with the spectral characteristics of rhodopsin.

Adolescent↗

Progress of visual dysfunction in Parkinson's disease.

Studies on progression of Parkinson's disease (PD) mainly focus on the nigrostriatal dopaminergic decline, but not on the visual system. We determined progression of (i) disturbed color vision, assessed with the Farnsworth-Munsell 100 Hue test (FMT) and (ii) intensity of PD in 18 patients. Significant differences occurred between (i) initial FMT error scores and follow-up results 3 years later (P=0.002) and analogously (ii) scored intensity of PD (P=0.002). A relation between computed differences of FMT error scores and rated activities of daily living appeared. Deterioration of color vision progresses in PD.

Color Perception↗

Preretinopic changes in the colour vision of juvenile diabetics.

AIMS: To examine the colour vision of juvenile patients suffering from diabetes mellitus without retinopathy in relation to metabolic and ophthalmic state. METHODS: Metameric matches, both Rayleigh (red/green) and Moreland (blue/green) were used to test the colour vision yearly of 10 juvenile patients. The patients were monitored over 4 years, and during the final year, their blood glucose level was determined directly after testing colour vision. An ophthalmic examination was performed on the day of colour vision testing and blood and urine were analysed regularly throughout the 4 years. Their results are compared with an aged matched control group of 20 subjects, seven of whom were retested after 9-16 months. RESULTS: After 4 years, the colour vision results show an enlarged matching range for the Moreland match, as well as a smaller increase in the matching range for the Rayleigh match. No significant correlation was found between blood glucose at the time of testing and any of the variables measured. CONCLUSION: The pattern of colour vision deficits in metameric matching shown by juvenile diabetics is consistent with postreceptoral alterations of the inner retina, at this preretinopic stage of disease. Duration of diabetes is correlated with both colour vision changes and morphological alteration of the retina.

Adolescent↗

Bishnupur achromats and their relatives (an exploratory study with six colour vision tests).

Thirteen subjects from the 'Sankhabaniks' of Bishnupur and two new similar cases were given six colour vision tests. All had photophobia, fixation nystagmus, low visual acuity and marked, though not complete, loss of colour sense. Forty other males and 24 females related to the defectives were also tested with at least five of the tests, for comparison. The tests were Ishihara, HRR test, Sloan's Achromatopsia test, the Dichotomous (D 15) test, Hundred Hue test and the Pickford-Nicolson Anomaloscope. The present research confirmed the provisional conclusion of Bose et al. (1968) that the achromatopsia in Bishnupur is an autosomal recessive character. That women relatives of the achromats showed greater average error scores with the Dichotomous test, the Hundred Hue test and the Sloan's test than male relatives, suggests that the defect is more readily manifested in males, and that the female relatives would include a number of genetic defectives with incomplete manifestation due to sex control. The defectives were clearly distinguished from the relatives as a group.

Adult↗