[Selection of the method of operation in the surgical treatment of diffuse polyposis of the large intestine].
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The author presents an analysis of 1603 clinical observations. By means of electronic computors the possibility to determine interrelations and dependence between forms of the disease and symptoms was realized. A computor recorded 156 possible variants of combinations of the forms and clinical manifestations.
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A family, the members of which suffer from "Gardner's syndrome" is reported. In this family, and also in another family which is being treated in our clinic with a diagnosis of "familial polyposis of the large intestine", bronchiectasis appears with a frequency more than can be attributed to chance. Our observations suggest the following conclusions: 1. Gardner's syndrome and familial polyposis of the large intestine are diseases which cannot be strictly separated from each other, but the isolated intestinal polyposis is a monosymptomatic form of Gardner's syndrome. 2. Bronchiectasis can be considered a further symptom of this disease caused by a pleiotropic effect of a gene.
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