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At least 469 records · Page 26Linked to original sources

An epizootic among knots (Calidris canutus) in Florida. I. Disease syndrome, histology and transmission studies.

About 150 knots found sick or dead had distention of serosal blood vessels, and small, raised hemorrhagic foci on the serosal surface of the jejunum and ileum. The principal finding was endaortitis with large intimal multinucleated cysts that contained a protozoan parasite within a cytoplasmic vacuole. There was endarteritis of mesenteric arteries and muscular arteries of the external layers of the intestinal tract. Single or multiple schizont-like stages containing zoites were in the wall of the small intestine and close to affected muscular arteries. The more usual intestinal lesion was an aneurysm of the inflamed muscular artery. It was concluded that endarteritis led to colonic infarction. Schizonts in medullary renal tubular cells were smaller than stages in the intestine. There was necrosis of epithelial cells of themedullary collecting ducts and inflammatory and regenerative changes. Schizonts and zoites were free in collecting ducts and ureters.

Animals↗

An epizootic among knots (Calidris canutus) in Florida. II. Ultrastructure of the causative agent, a Besnoitia-like organism.

Multinucleated cysts near the luminal surface of the thoracic aortas of diseased knots (Calidris canutus) were similar to besnoitia cysts. Ultrastructurally, the cyst had four distinct layers. The central area included a vacuole that contained a sporozoan with a conoid, polar ring, micronemes, rhoptries, nucleus, mitochondria, dense bodies, a lipid-like vacuole and endoplasmic reticulum. External to the vacuole was a layer with organelles typical of vertebrate cells. The wall of the cyst was irregular in thickness and was bound by a strongly osmiophilic membrane. There was a loose, acellular area of intertwined strands between the cysts wall and layer of organelles.

Animals↗

Encephalitozoonosis in squirrel monkeys (Saimiri sciureus).

Twenty-two cases of naturally occurring encephalitozoonosis in squirrel monkeys are reported from breeding colonies of the Delta Regional Primate Research Center, Covington, La. Characteristic foci of granulomatous inflammation and organisms were demonstrated in brains, kidneys, lungs, adrenals, and livers. Vasculitis and perivasculitis were also common lesions in several organs. At least seven cases were congenital while ten others occurred in monkeys less than nine months old. Granulomatous placentitis, previously unreported in any species due to Encephalitozoon cuniculi, was present in one monkey.

Animals↗

Henneguya exilis Kudo associated with granulomatous branchitis of channel catfish Ictalurus punctatus (Rafinesque).

Outbreaks of a chronic branchitis in channel catfish Ictalurus punctatus (Rafinesque) were observed on four fish farms throughout the state of California from November 1982 to April 1984. Severe granulomatous inflammation of the gill filaments with necrosis of the cartilage of the gill ray and diffuse epithelial hyperplasia, resulting in extensive fusion of gill lamellae, was present on histologic examination of gill specimens from 35 out of 44 fish examined. Numerous, small trophozoites morphologically consistent with presporogonic myxosporean parasites were consistently associated with the inflammatory process. Mature spores of Henneguya exilis Kudo were present in large numbers in gill specimens from two fish and only occasionally in 22 others. Similar cases referred to as "Hamburger Gill Disease" or "proliferative gill disease" have been known to occur in the south-central United States. This report describes the morphologic changes of this condition and discusses its possible pathogenesis.

Animals↗

Fetal and placental lesions in bovine abortion due to Tritrichomonas foetus.

Laboratory records and histologic material from 13 cases of naturally occurring, early- to late-term bovine abortion due to Tritrichomonas foetus were examined. Placentitis was present in all placentas. Pyogranulomatous bronchopneumonia was in six of the 11 lungs which were examined. Trichomonad organisms were demonstrated within the placental stroma in all cases and free or phagocytized in pulmonary airways in seven cases.

Abortion, Veterinary↗

Intestinal trichomonads (Tritrichomonas mobilensis) in the natural host Saimiri sciureus and Saimiri boliviensis.

A retrospective study of cecal and colonic tissues from 28 squirrel monkeys (Saimiri sciureus and Saimiri boliviensis) demonstrated enteric trichomonads within luminal crypts. Twenty-one of 28 (75%) had trichomonads in the mucosal epithelium either in cup-like depressions or intraepithelial vacuoles. Organisms were also beneath the superficial luminal mucosal epithelium and between the basement membrane and crypt epithelial cells. Immunoperoxidase staining also identified organisms within the lamina propria and submucosa. Additional histologic changes included mucosal ulceration, multifocal cryptitis, and focal epithelial necrosis. Most areas containing trichomonads did not have an associated inflammatory response.

Animals↗

Neosporosis in cats.

Six cats (Nos. 1-6) were inoculated intramuscularly with (1 x 10(6)) and orally (5 x 10(5)) tachyzoites of Neospora caninum. Three (Nos. 1-3) of the six cats were given 40 mg/kg methylprednisolone acetate 7 days before and on the day of inoculation with N. caninum tachyzoites, and three cats (Nos. 4-6) were not given methylprednisolone acetate. Two of the cats (cat Nos. 1 and 2) given methylprednisolone acetate died suddenly. Cat No. 1 died 8 days post-inoculation, and cat No. 2 died 16 days post-inoculation. Cat No. 3 was euthanatized 21 days post-inoculation. Cat No. 1 had lesions of gram-positive bacterial septicemia. Necrotizing encephalitis, myelitis, disseminated skeletal muscle necrosis, hepatic necrosis, interstitial pneumonia, and renal tubular necrosis were the main lesions in cat Nos. 2 and 3. The cats that were not given methylprednisolone acetate remained clinically normal except for slight weight loss in cat No. 6. All three of these cats were euthanatized 55 days post-inoculation. Mild myositis and encephalitis were noted on microscopic examination of tissues from these three cats. Neuromuscular lesions were not seen in six control cats (Nos. 7-12) not inoculated with N. caninum and euthanatized 21 or 22 days after administration of the first two doses of methylprednisolone acetate (40 mg/kg), given at a weekly interval.

Adrenal Glands↗

Eosinophilic colitis and hepatitis in a horse with colonic intramucosal ciliated protozoa.

Tissues from a 9-year-old American Standardbred gelding with a history of anorexia, mild colic, and unexpected death were submitted to the Laboratories of Veterinary Diagnostic Medicine at the University of Illinois for histopathologic examination. Microscopic diagnoses were severe subacute, diffuse eosinophilic colitis with intralesional protozoa and a subacute to chronic eosinophilic portal hepatitis with granuloma formation. Two tissue-invading, ciliated protozoa were identified in large numbers within the colonic mucosa. The ciliates were Polymorphella ampulla and Cycloposthium sp., Phylum:Ciliophora. The eosinophilic colitis and portal hepatitis in association with the overpopulation and invasion by the ciliated protozoa suggests a causal etiology.

Animals↗

Neosporosis-like abortions in a herd of dairy cattle.

Twenty-nine cows from a 240-cow drylot Holstein dairy in north-central New Mexico aborted over a period of approximately 5 months. Nine aborted fetuses were necropsied, and all but 1 of the fetuses were between 5 and 7 months of gestation. Microscopic examination of fetal tissues revealed focal necrotizing encephalitis and nonsuppurative myocarditis in 7 of the 9 fetuses. Additional lesions observed in some fetuses were focal hepatic necrosis, nonsuppurative myositis, focal necrotizing placentitis, focal nonsuppurative pneumonia, and focal nonsuppurative nephritis. A few groups of Neospora caninum-like protozoan organisms were observed adjacent to necrotic foci in the brain of 2 fetuses and in the kidney of a third fetus. No other cause of abortion was detected.

Abortion, Veterinary↗