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At least 469 records · Page 26Linked to original sources
PubMed2000

Shifting paradigms in whitening: introduction of a novel system for vital tooth bleaching.

The advent of whitening strips (Crest Whitestrips) affords a novel system for peroxide delivery without custom tray fabrication. In addition to generalized bleaching indications, clinical applications may leverage the low overall dose and short wearing regimen with the easy-to-use strips. The impact of these strips on the dental practice may be direct, as a result of increased accessibility via professional or personal use, or indirect, because of advertising and research in the area of tooth whitening.

Drug Delivery Systems↗
PubMed2003

Rapid palatal expansion in the young adult: time for a paradigm shift?

A 19-year-old man presented for correction of a malocclusion that included a transverse maxillary deficiency. The patient was informed that he required orthognathic surgery to expand his upper jaw and correct his malocclusion, but he refused surgical expansion. Recent evidence indicates that rapid palatal expansion can be used without surgery in young adults; the decision was therefore made to treat the patient nonsurgically. Rapid palatal expansion of the maxillary arch was accomplished by means of a Hyrax appliance, with post-treatment radiographs revealing an opening of the midpalatal suture. The belief still persists among some clinicians that young adult patients require orthognathic surgery for palatal expansion, despite recent evidence supporting a nonsurgical approach after closure of the midpalatal suture.

Adult↗
PubMed2002

Corporate response to the HIV/AIDS epidemic in Uganda - time for a paradigm shift?

The HIV/AIDS epidemic is likely to remain the pre-eminent global health concern for the foreseeable future. In Uganda, while significant progress has been made by the government over the past decade in bringing down the rate of new infections, the HIV/AIDS burden in the country remains huge and vigilant efforts must be continued if this burden is to further decrease. Traditionally the government, supported by its international partners as well as local non-government organizations and the community has borne the brunt of the costs of containing the epidemic in Uganda. While the corporate sector in the country has financially contributed towards the costs of some of the interventions that are currently in place to combat the HIV epidemic, there is largely a paucity of sustained and systematic corporate leadership in providing comprehensive HIV/AIDS programmes for their employees. A survey done by the authors of this paper reveals that most programmes undertaken in the private sector are of limited scope. We argue that there is more the corporate sector can do to more equitably share the HIV/AIDS burden, without necessarily jeopardizing its primary role - namely to maximize returns to shareholders. This paper proposes a conceptual framework of how companies can approach the issue of HIV/AIDS within their workforce and suggests that providing more comprehensive interventions may in some instances result in substantial cost savings through the prevention or at least delay of HIV/AIDS related consequences such as: frequent absences from work, erosion of company skills and knowledge through key employee deaths, and the costs of hiring and training replacements etc. This ultimately could result in positive financial returns to those companies that choose to pursue work place led HIV/AIDS control and prevention programmes.

Cost of Illness↗
PubMedDate not supplied

Molecular genetics of cardiomyopathy: changing times, shifting paradigms.

Congestive heart failure is a major problem in developed and developing countries alike. Primary dysfunction of the heart muscle accounts for a significant proportion of patients with a non-ischaemic cause of heart failure. Application of genetic techniques has facilitated identification of some molecular causes of the inherited form of these diseases, dramatically increasing our understanding of the pathogenesis of these primary, previously termed 'idiopathic', cardiomyopathies over the last few decades. Knowledge of the different causes is beginning to coalesce into aetiological principles underlying the clinically distinguished cardiomyopathies. Hypertrophic cardiomyopathy (HCM) now appears to be a disease caused by a dysfunctional sarcomere, dilated cardiomyopathy (DCM), a disease of myocytic structural instability, and arrhythmogenic right ventricular cardiomyopathy, a disease of accelerated myocyte death. The aetiology of both HCM and DCM probably also involves cardiac energy imbalances, while additional factors modify the clinical expression in all cardiomyopathies. Even though our knowledge of the genetic aetiology of the cardiomyopathies is still incomplete, it already has relevant clinical significance. Elucidation of the full genetic contribution to the development and progression of the cardiomyopathies represents a new challenge in the study of these diseases, and will undoubtedly lead to new therapeutic approaches in the not-too-distant future.

Cardiomyopathy, Dilated↗
PubMed2003

[Health instead of gallantry: a paradigm shift in physician's beauty advice in the century of enlightenment].

The views of femininity and the attempts to standardise it, developed in the 18th century in philosophy, education, literature, theology, anthropology and medicine, have led to intense research in the last years. Such research normally starts with the Enlightenment debates in the second half of the 18th century, but there are interesting sources which allow the tracing of a development over a longer period and which had a wider contemporary readership than any scholarly treatise. These are the popular beauty manuals, which in the German-speaking area started to appear more frequently from the late 17th century on, composed chiefly by physicians who thereby hoped to profit from the growing book and healthcare market. The present article considers the approaches of physicians to female beauty, with special reference to the discontinuities caused by the Enlightenment.

Attitude of Health Personnel↗