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PubMed1981

[Simultaneous or successive locations carcinomas of head and neck (author's transl)].

204 simultaneous or successive locations of carcinoma were observed and analysed in a series of 1992 cases of head and neck carcinomas for 15 years (10.24 p. 100). Simultaneous carcinomas appeared electively in single anatomical area: hypopharynx, oropharynx, endolarynx. Successive carcinoma on the other hand are developed in adjacent anatomical sites. An oesophagal location worsens the prognosis; the related facts and rules are analysed for their frequency. An early detection II counselled and their pathogenesis is discussed.

Adult↗
PubMed1980

Mortality of welders, shipfitters, and other metal trades workers in boilermakers Local No. 104, AFL-CIO.

The mortality experience of 8679 members of a metal trades union--men employed in shipyards, metal fabrication shops, small boat yards, and field construction--was studied from 1950 to 1976 by the historical prospective method. Relative to rates for US men of comparable age and race, the risk of death from all causes combined was 0.99. However, excesses of 40 per cent (p < 0.001) and 60 per cent (p < 0.001) occurred for malignant and nonmalignant respiratory disease deaths, respectively, beginning 20 years after first employment. The mortality excesses from malignant and nonmalignant respiratory diseases increased with increasing interval from first employment; and the nonmalignant respiratory disease excess was also related to cumulative exposure. Causes of death that occurred at significantly (p < 0.05) greater than expected rates in specific job classifications included pneumonia in welders, accidents and suicide in shipfitters, and emphysema in burners.

Adult↗
PubMed1993

Survival of Danish cancer patients 1943-1987. Respiratory system.

Cancers of the respiratory system are among the most common types of malignant neoplasms in the industrialized world. Thus, this group constitute about 20% of all male and about 8% of all female cancers diagnosed in Denmark during the recent years. Altogether respiratory cancers contribute with around 3,700 (14%) new cases of the about 26,000 cancers diagnosed a year, including skin cancers. Since lung cancer, which in general have a very bad prognosis with a relative 5-year survival of 6%, is the far major cancer subtype in the respiratory system (about 90% of all respiratory cancers), the survival of all respiratory cancers combined is poor. However, the survival of the relative rarely sinonasal and laryngeal cancers are fairly good with 5-year relative survival rates in men of 47% and 61% and in women of 51% and 62%, respectively, during the 1980s. In general, only very small improvements in survival during the period of registration have been observed, the largest being in sinonasal neoplasms, where the 5-year relative survival for the men have increased from 18% around 1945 to 47% around 1985, and for the women from 30% around 1945 to 51% around 1985. Since the aetiology of the major part of respiratory cancers is fairly known, i.e. especially tobacco smoking and to some extent several factors in the working environment, it seem most likely that the major progress will come from primary prevention.

Age Factors↗
PubMed1995

[Assessment of cancer risk in the general population of Poland due to asbestos exposure. I. Basis of methodology].

Two mathematical models facilitating calculation of cancer risk in people exposed to asbestos dust in the communal environment are discussed. The first helps determine a dose-response relationships when lung cancer is the exposure effect whereas the second permits calculating the probability of pleural or peritoneal mesotheliomas induction based on the level of asbestos exposure. In the case of lung cancer, the exposure is measured as a cummulated dose which equals to a product of an average concentration of asbestos fibres in 1 ml of the air multiplied by duration of exposure (in years). Thus determined relationship between asbestos exposure and the risk involved is a linear function. The effect of smoking, which undoubtedly accounts for lung cancer induction, is an element of the assessment in this model. The relationship between the risk of mesothelioma and exposure level, which is a non-linear function, is associated with the duration of exposure (in years) and the number of years since first asbestos exposure, however, it is not related to the age of person when first exposure occured or smoking habit. It may assumed that, in the case of environmental exposures, the level of exposure could be measured by the duration of exposure to a determined concentration (the exposure starts at birth to be continued throughout the whole lifetime until death). The models presented allow forecasting cancer risk based on the adopted level and duration of exposure to asbestos dust.

Aged↗
PubMedDate not supplied

Video-assisted thoracic surgery (VATS) for cancer. Risk of parietal seeding and of early local recurrence.

Both parietal seeding and early local recurrence have been anecdotally (24 cases) reported in the surgical literature after video-assisted thoracic surgery (VATS) for cancer. However, not all the cases reported were undoubtedly related to the thoracoscopic approach itself, several of those thoracoscopic procedures addressed locally advanced neoplastic processes, and protective measures against parietal contamination were not taken in one half of the patients. Strict adherence to the classic principles of carcinologic surgery should minimize the risk of both parietal and pleural grafting after VATS for cancer.

Humans↗