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Sporotrichosis.

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Humans↗

Gallium-67 citrate localization in disseminated sporotrichosis.

A 25-year-old woman demonstrated Ga-67 citrate accumulation within a facial cutaneous lesion and two subcutaneous nodules within the right lower extremity. Cultures of the facial lesion and one of the subcutaneous nodules grew Sporothrix schenckii. Ga-67 citrate uptake has not been reported previously with this fungal infection. Ga-67 citrate scintigraphy was helpful in defining the extent of the disease, following its course, and determining the response to therapy.

Adult↗

Three-phase bone and Ga-67 scintigraphy in disseminated sporotrichosis.

A 27-year-old man, who had been shoveling gravel in southern Texas for 3 years, had a history of papules and nodules in the left lateral wall of the abdomen. The lesions increased in number and severity with spread to other regions of the body. A punch biopsy of the right arm lesion revealed intracellular, round and cigar shaped budding yeast. The cultures grew Sporotrichum schenkii. Three-phase bone imaging and a Ga-67 scan defined the extent of the disease including involvement of the right tibia, left second metacarpal, and the left wrist joints, the latter two of which were not apparent on clinical examination.

Adult↗

Conjunctival sporotrichosis in the absence of antecedent trauma.

PURPOSE: To describe a patient with conjunctivitis. METHODS: Case report and review of the literature. RESULTS: A 34-year-old cattle farmer with no history of trauma developed gradual onset of an inflamed bulbar conjunctival mass associated with ipsilateral preauricular lymphadenopathy. Excisional biopsy of the conjunctival mass and subsequent histopathologic examination revealed suppurative granulomatous inflammation and small budding yeasts. Electron microscopy confirmed the presence of small intracellular and extracellular yeast organisms. Cultures grew the dimorphic fungi Treatment with oral itraconazole and topical fluconazole resulted in complete resolution of the infection. CONCLUSION: characteristically infects the skin and regional lymphatics after penetrating trauma, but atraumatic infection of pulmonary mucosal surfaces can occur upon inhalation of the fungal spores. Our case report suggests that atraumatic exposure to may be sufficient to establish conjunctival infection.

Adult↗