Stretch and growth: the molecular and physiologic influences of tissue expansion.
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A randomized controlled trial of 11 pairs of random-pattern skin flaps in pigs was observed. The flaps (5 x 16 cm) were divided into two groups: experimental group (EG)--the flaps were inflated with controlled expanders placed into subcutaneous tissue of the back of pigs; control group (CG)--the same expanders were placed into subcutaneous tissue of other side but not inflated. After the test period of 5 weeks, the results showed that the mean surviving length of flaps was 13.58 cm in EG and 9.40 cm in CG. The ratio of length to width was 2.72:1 in EG and 1.88:1 in CG. The differences between two groups were statistically significant (P less than 0.001). The result indicates that the random-pattern skin flaps inflated by expanders can be greatly increased the ratio of length to width. It is suggested that the increase of surviving length of the flaps in EG results from the increment of blood vessel and the enlargement of vessel diameter along the long axes of the flaps.
We describe a successful approach to the management of the webbed neck deformity in Turner's syndrome using skin expansion. This case report demonstrates the advantages of this method over previously described techniques.
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Based on a 24 mammary expansion implants performed in 14 cases of deferred breast reconstruction and in 7 cases of asymmetry, the authors analyze their results and indications according to data reported in the recent literature data. In breast reconstruction, expansion represents a relatively simple surgical procedure allowing an increase of local tissues without any additional scars. Its indications correspond to the gap left between simple prosthesis and musculo cutaneous flaps and are based on a clinical analysis of the volume and quality of mammary tissues considering that radiotherapy constitutes more factor of morbidity than a real contra-indication. A strict selection of patients allows reduction of the complications (6% prosthesis extrusions and 6% contractures in this series) that remains quite high (30%) in the literature. Based on two main operative steps, the reconstruction needs, in the great majority of cases, several complementaries operative sequences increasing to 2.4 in their series, and to 2.6-2.8 the average number of operative steps in literature. For breast asymmetry, expansion was correlated in this series to a higher incidence of complications and especially capsular contractures, leading to a limitation of their indications to cases in which the benefit is maximal in relation to an important glandulocutaneous deficit. These indications are in which hypoplasia with superointernal malposition of the nipple areola complex where the effect of expansion is maximal in the inferointernal mammary area and tubular and tuberous breasts, in which expansion allows a widening of the base of the breast and breaks the fibrous ring at the base of the breast.
Massive ventral hernias may result from a variety of clinical situations. One such clinical situation, a common problem in trauma patients, is abdominal compartment syndrome. Abdominal compartment syndrome frequently results in a massive abdominal defect when primary closure after surgical decompression is not possible. We offer a technique for repairing these massive ventral hernias by first expanding the lateral abdominal wall muscles, fasciae, and skin with tissue expanders and then closing the defect with elements of the "components separation" method. Additionally we present other clinical situations resulting in a massive ventral hernia that were repaired using this technique.
The capillary blood flow (CBF) of the random flaps constructed on expanded and unexpanded skin of dogs was determined by radioactive microsphere technique. The CBF was significantly higher (P < 0.001) in the skin flaps of the expanded group (387 +/- 23 microliters/min/flap) than that of the acute group (127 +/- 16 microliters/min/flap). There were no significant differences in the expanded group, the delayed group (374 +/- 35 microliters/min/flap) and the control group (389 +/- 48 microliters/min/flap). Even at the pedicle site, the CBF of the acute group was already significantly lower than that of other three groups (P < 0.001). The general tendency of gradual CBF reduction from the pedicle to the distal end of all the flaps was observed. The CBF at the point 8cm from the pedicle of the acute group was 12 microliters/min/g, whereas in other three groups, at point 13 cm from the pedicle the CBF was 12 microliters/min/g. The results suggested that during skin expansion the area of skin is enlarged, and its CBF and survival length may be increased. The problem of capsulectomy during flap construction was discussed.
The oblique facial cleft may present as a cutaneous and/or an osseous cleft, with or without a cleft lip, and with or without a cleft palate. This particular case was born with complete bilateral cutaneous-osseous oblique facial clefts which extended from the oral cavity to the eye sockets with anophthalmia on the right side. The first surgical intervention included a midline nasal skeleton alignment and bilateral cleft lip and alveolus reconstruction. Urinary Foley catheters were used as facial tissue expanders and inserted adjacent to the oblique facial clefts. The second surgical procedure consisted of a partial pyramidal Le Fort II osteotomy for an inferiorly displaced nasal maxillary skeleton and a rotation and advancement of the cheek as a flap for reconstruction of the palpebral cleft and inner canthus.
The surgical technique to correct the webbing deformity of the neck by Z-plasty corrects the deformity but leaves disfiguring scars over the lateral aspect of the neck, and the hair-bearing skin is transposed anteriorly. Butterfly correction and the lateral cervical advancement flap again correct the deformity and the low hairline but leave disfiguring scars over the posterior aspect of the neck. Recurrence is possible as a result of increased tension on the skin posteriorly. In the method described in this paper, the insufficient skin of the lateral aspect of the neck is expanded by tissue expanders. The excess skin is then advanced posteriorly, and redundant skin is excised following removal of the expanders. This corrects the webbing deformity and the low hairline, leaving a small vertical scar in the midline and a horizontal scar at the occipital area within the hairline.
Temporary hyperexpansion at each filling session has previously been confirmed to increase the inflation volume in a conventional expansion procedure. This study employed eight young pigs to evaluate the effect of hyperinflation of this type in rapid expansion performed on 10 consecutive days. Hyperinflation to 120 mmHg for 4 minutes and deflation to 40 mmHg for 2 minutes was repeated five times on the experimental side. This cycled hyperinflation was found to increase the filling volume by 49 percent when compared with the contralateral side, which was not cycled or hyperinflated (control) (p < 0.01). The increase in surface area of the entire skin over the balloon was 178.1 percent in the hyperinflation group and 132.8 percent in the controls (p < 0.01). The actual expansion in surface area was not significantly different: 44.4 percent in the hyperinflation group and 45.7 percent in the control group. The additional gain of skin by cycled hyperinflation was the result of recruitment. The control group required 5 more days to achieve the same amount of skin but resulted in more true expansion and less recruitment. It is concluded that the cycled hyperinflation technique may shorten the time period of the whole reconstruction procedure but may produce an aesthetic deformity and flap necrosis.
The authors start by recalling the principal histomorphological and physiological characteristics of skin tissues subjected to expansion, in particular their hyper-vascularisation which allows the raising of vast flaps of excellent quality. After presenting the major principles, they then present their clinical experience in the context of reconstructive surgery of the scalp, particularly in the correction of Juri flap scars used in the treatment of baldness. Finally, they emphasise the great potential of this technique in the whole field of reconstructive surgery.
Thirty-three patients have had skin expansion for reconstruction in the head and neck area. Expansion was used alone in 21 patients, and combined with other techniques in 12 patients. Indications, operative technique, complications and failures of the method are discussed.
Elongation of peripheral nerves would facilitate the repair of peripheral nerve injuries. The purpose of this study was to determine the efficacy of nerve expansion and the effect of different levels of intraluminal expander pressure upon nerve conduction. A 2-mL Silastic expander was placed under one sciatic nerve of adult male rats. The other nerve served as a control. Electroneuromyography (ENMG) was done at the time of initial expansion in seven animals. At 40 mm Hg expansion pressure a significant change in latency was found with an increase of 17% +/- 5%. Expansion was carried out for 14 days in two groups of seven rats, group I at 20 mm Hg and group II at 40 mm Hg. Length gain on the expanded side was 30% in group I and 40% in group II. No significant changes in latency or velocity were found after expansion. We conclude that nerves can be expanded at low pressures with no significant conduction changes but long-term recovery of histologic changes needs to be evaluated.
The authors report their experience of cutaneous expansion in a retrospective study of 78 cases. They compare the two methods usually applied: discontinuous slow expansion in two thirds of cases versus rapid continuous expansion in one third of cases. Both methods, as they are defined in the department, are described. Statistical analysis revealed two important facts: the complication rate was considerably lower in continuous expansion. Length of hospital stay was similar for both techniques. The results, not yet studied in a strictly scientific way, do not appear to argue against continuous expansion. Rapid cutaneous expansion may be considered to be a valuable technique in the future, but it must be chosen for certain people only and must be adapted to each patient.
Dissecting folliculitis of the scalp can develop into an extensive, hypertrophic scarred lesion that is unresponsive to routine treatment. In these situations, radical excision of the affected area and concurrent perioperative treatment with isotretinoin (13-cis-retinoic acid) may be effective. The authors describe a case, illustrating the successful clinical application of this technique.
Burn scars of the lower part of the face are a difficult problem in plastic surgery. Full thickness skin graft or local flaps usually give poor cosmetic result. Over the last 5 years, we used 24 skin expanders in the neck area to cover burn scars of the chin and jaw. Discussion of the method and 4 cases are reported.