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The paleopathology of an Aleutian mummy.

A multidisciplinary team examined an Aleutian mummy from the collection of the Peabody Museum of Archeology and Ethnology of Harvard University, Cambridge, Mass. The mummy, dating from the early 18th century, was of a middle-aged woman who had suffered from pulmonary and ear infections, atherosclerosis, pediculosis, and degenerative joint disease. Another finding was anthracosis, common in ancient bodies and related to indoor heating and cooking fires. Skeletal lead was not found, in contrast with the high levels seen in modern persons. No neoplasms were identified, again consistent with the results of previous studies of ancient human remains. Such comparisons of ancient and modern morbidity and mortality provide a historical perspective on the evolution and cause of human disease.

Alaska↗

[Cell populations recovered by bronchoalveolar lavage in pneumoconiosis of coal miners].

Studying the cellular products obtained by broncho-alveolar lavage in 81 patients, 77 coal-miners and 4 other subjects exposed to silicotic risks of various origin, the authors could demonstrate the interest of this new method of exploring the peripheral lung tissues. In 57 cases of usual pneumoconiosis and controls matched for the smoking habits, the repartition of the different cellular types was quite similar. On the contrary, the authors observed an increase of the lymphocytes in three cases of accelerated elution of the pneumoconiosis. Moreover various modifications were noticed in cases with morbid associations as conectivitis, sarcoïdosis, allergic alveolitis, and primitive diffuse interstitial fibrosis as well. At the moment they were collected, the alveolar macrophages of the subjects to dust showed the same properties of vitality and adherence capacity as the controls. After 24 hours of survival their vitality and bacterial activity on staphylococcus aureus was clearly diminished.

Adult↗

[Clinical application of ultra-thin bronchofiberscope examination].

Ultra-thin bronchofiberscope examination has been performed in 73 persons including normal persons and patients with various bronchopulmonary disease. The main lesions of peripheral airways revealed by the examination were reddening, pigmentation, secretion, engorgement of blood vessels, mucosal pallor and edema. The result points out that this is a valuable new technique in the diagnosis of small airway lesions, especially the diffused inflammatory of small airways. In case of a localized lesion, because of the difficulty to precisely determine the site, the effectiveness of this examination is limited. We also briefly discussed the matters that one should pay attention to while performing this technique.

Adult↗