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Perception of direction of visual motion. I. Influence of angular body acceleration and tilt.

We investigated, psychophysically, the influence of body rotation on visual motion direction thresholds for both upright sitting and tilted observers. Four angular accelerations (0, 20, 40 and 60 degrees/s2) were combined with 3 concurrent backward-tilt positions (0, 45 and 90 degrees). This led to combined stimulation of the semicircular canals and otoliths. Vestibular stimulation was combined with a visual motion stimulus. Random-dot kinematograms in which varying percentages of pixels coherently moving to the left were presented upon a background of otherwise randomly moving pixels (random walk). The smallest percentage of coherently moving pixels leading to a clear perception of motion direction represented as the perceptual threshold. Angular accelerations about the longitudinal body axis significantly increased motion-direction thresholds. Concurrent backward tilt did not influence thresholds. These results differ from those of studies in which translational linear acceleration was employed. Our results support the view that it is necessary to distinguish between linear acceleration caused by gravitational forces and that caused by additional linear accelerations about the x-, y-, and z-axes.

Acceleration↗

Short latency vestibular evoked potentials (VsEPs) to linear acceleration impulses in rats.

In this study, short latency (t < 12.7 ms) vestibular evoked potentials (VsEPs) in response to linear acceleration impulses were recorded in 37 rats. A new technique (based on a solenoid) was used for generating linear force impulses that were delivered to the animal's head. The impulse had a maximal peak acceleration of 12 g. During the impulse, the displacement was 50 microns (at 4 g) and the rise time was 1.0 ms. A stimulation rate of 2/s was usually used. The VsEPs (averaged responses to 128 stimulations, digital filter: 300-1500 Hz) were recorded with electrodes on pinna and vertex, and were composed of 4-6 clear waves with mean amplitudes (for a 4 g stimulus) of 1-5 microV. The VsEPs were resistant to white noise masking, and were significantly suppressed (P < 0.05) following bilateral application of a saturated KCl solution to the inner ear, showing that contributions of the auditory and somatosensory systems are negligible. The latency of the response decreased as a power law function of stimulus magnitude, and the amplitude of the first wave increased as a sigmoid function of stimulus magnitude. VsEP responses were still present at the lowest intensities attainable (0.06-0.4 g) and reached saturation at 9 g. The amplitude of the later components was reduced when stimulus rate was elevated to 20/s. These results suggest that VsEPs in response to linear accelerations are similar in their nature to VsEPs in response to angular acceleration impulses that were previously recorded. These VsEPs to linear accelerations are most likely initiated in the otolith organs.

Acceleration↗

Wedge filter effects on dosimetric parameters of a linear accelerator.

The open-field and wedged-field output factors as a function of field size for two linear accelerators were measured. Wedge factors were determined by taking the ratio of the outputs with and without the wedge filter. For one linear accelerator, the difference in the output factors between the wedged field and open field can be as large as 5%. The wedge factor for this linear accelerator also varies with the field size. On the other hand, the other linear accelerator shows smaller variation of output factors between wedge field and open field. The variation of wedge factor is less than 1% for a 60 degree wedge. In addition to modifying the isodose distributions, the wedge filter also changes the percent depth dose curves, the output factor, and the wedge factor. The degree of wedge effects on these dosimetric parameters is different for different linear accelerator.

Filtration↗

Acceleration threshold detection during short anterior and posterior perturbations on a translating platform.

Balance control systems have usually been studied under two conditions, during quiet standing or under large postural perturbations of a magnitude that requires a postural adjustment to prevent falling. Between these two extremes lie perturbations that can be repeated and measured while not forcing adaptive strategies from the postural control system. Unlike other studies of postural control, we employed very short translations with varying accelerations at the edge of psychophysical detectability. These perturbations were vibration-free anterior or posterior translations of the platform on which a subject stood. Using a full Latin-square design set of perturbations in the forward or backward direction, with a smooth or jerk acceleration profile, and of length 4 or 20 mm, were presented to five subjects. Perceptual peak acceleration thresholds were determined by an iterative psychophysical method that forced the subjects to choose in which of two sequential intervals that they perceived a stimulus to have been presented. The only factor found that significantly correlated with detection was perturbation length. The 4 mm peak thresholds averaged 14.51 mm/s2 while 20 mm thresholds averaged 8.55 mm/s2. For the short perturbations employed in this study, detection of motion thus was dependent upon the magnitude of the acceleration, but it was independent of the acceleration profile (jerk versus smooth) or movement direction. By understanding the influences on the ability to perceptually detect motion underfoot, we can begin to understand what elements of the postural control system might be involved in the second-to-second control of balance.

Acceleration↗

Classification of waist-acceleration signals in a continuous walking record.

We attempted to distinguish walking on level ground from walking on a stairway using waist acceleration signals. A triaxial accelerometer was fixed to the subject's waist and the three acceleration signals were recorded by a portable data logger at a sampling rate of 256 Hz. Twenty healthy male subjects were asked to walk through a corridor and up and down a stairway as a single sequence, without any instruction. The data were analyzed using discrete wavelet transform. Walking patterns were classified in two stages. In the first stage, the times when the walking pattern changed were detected using the low-frequency component of the anteroposterior acceleration (LF(A)) and of the vertical acceleration (LF(V)). In the second stage, the three types of walking patterns were classified by comparing powers of wavelet coefficients in the vertical direction (P(WCV)) and in the anteroposterior direction (RP(WCA)). Changes in walking patterns could be detected by using either LF(A) or LF(V). Walking down stairs could be distinguished from the other types of walking as it gave the largest value in P(WCV), and walking up stairs could be discriminated from level walking using RP(WCA). Level and stairway walking could be classified from continuous records of waist acceleration.

Acceleration↗

Perception and extrapolation of velocity and acceleration.

A moving target disappeared behind a screen and subjects predicted when the target passed behind a marker on the screen. When the target moved with constant velocity, predictions were extremely accurate, regardless of the spatial and temporal exposure and concealment of the target and regardless of its rate of velocity. When the target accelerated, accuracy of prediction decreased with increasing acceleration and with increasing target concealment. Analyses of the results suggest that the perception of velocity and acceleration is direct and accurate and that extrapolation of velocity and acceleration incorporates concrete and abstract characteristics of the motion that was seen. It is proposed that the motion perception system is tuned to accelerated rather than to constant velocity movement.

Acceleration↗

Visual reaction times during prolonged angular acceleration parallel the subjective perception of rotation.

The effect of prolonged angular acceleration on choice reaction time to an accelerating visual stimulus was investigated, with 10 commercial airline pilots serving as subjects. The pattern of reaction times during and following acceleration was compared with the pattern of velocity estimates reported during identical trials. Both reaction times and velocity estimates increased at the onset of acceleration, declined prior to the termination of acceleration, and showed an aftereffect. These results are inconsistent with the torsion-pendulum theory of semicircular canal function and suggest that the vestibular adaptation is of central origin.

Acceleration↗

Role of image acceleration in judging landing location of free-falling projectiles.

The vertical acceleration of the projective image of a free-falling object specifies whether the object will land behind or in front of the observation site. Human sensitivity to this visual cue was investigated in 4 studies. Experiments 1 and 2 examined sensitivity to both constant and accelerating vertical acceleration. Detection of acceleration required a total change in velocity that was about 20% of the average velocity. In Experiments 3 and 4, subjects judged where computer-simulated free-falling objects would land relative to the observation site by viewing the initial segment of the flight objects whose trajectories remained in the sagittal plane of the observer. Judgments were influenced significantly by the magnitude and direction of the image velocity change even when no error feedback was available, implicating image acceleration as a source of information for judging the landing site of free-falling objects.

Acceleration↗

Absorbed dose to technicians due to induced activity in linear accelerators for radiation therapy.

Absorbed dose to the trunk and to the hands of technicians working with accelerators for radiotherapy have been measured with TL dosimeters for seven different accelerators. The contribution from induced activity in the accelerator and from radiation transmitted through the walls of the treatment room have been estimated separately. The total annual absorbed dose to the trunk and to the hands have been estimated to be 2 mGy, of which the induced activity contributes one-third (0.7 mGy). The exposure of the technicians was found to be dominated by radiation penetrating the walls of the treatment room. For one accelerator the absorbed dose rate in the treatment room was measured continuously between 0.5 min and 48 h after end of treatment. Immediately after irradiation with high-energy photons the radiation is dominated by 28Al and 62Cu T1/2 = 2.3 and 9.7 min respectively) and later by radionuclides with longer half-lives, 187W and 57Ni (T1/2 = 24 and 36 h respectively). Due to these radionuclides the radioactivity in the accelerator will build up and the technicians will therefore be irradiated every time they enter the treatment room and not only directly after a treatment with high-energy photons.

Electrons↗

An MCNP-based model of a linear accelerator x-ray beam.

The Monte Carlo N-Particle radiation transport computer code (MCNP) has been employed on a personal computer to develop a simple model simulating the major components within the beam path of a linear accelerator radiation head, namely the electron target, primary conical collimator, beam flattening filter, wedge filter and the secondary collimators. The model was initially used to calculate the energy spectra and angular distributions of the x-ray beam for the Philips SL 75/5 linear accelerator, in a plane immediately beneath the flattening filter. These data were subsequently used as a 'source' of x-rays at the target position, to assess the emergent beam from the secondary collimators. The depth dose distributions and dose profiles at constant depth for various field sizes have been calculated for a nominal operating potential of 4 MV and found to be within acceptable limits. It is concluded that the technique may be used to calculate the energy spectra of any linear accelerator upon specification of the component dimensions, materials and nominal accelerating potential. It is anticipated that this work will serve as the basis of a quality control tool for linear accelerators and treatment planning systems.

Biophysical Phenomena↗

Acceleration patterns of the head and pelvis when walking are associated with risk of falling in community-dwelling older people.

BACKGROUND: A large proportion of falls in older people occur when walking, however the mechanisms underlying impaired balance during gait are poorly understood. This study evaluated acceleration patterns of the head and pelvis when walking on a level and an unpredictably irregular surface to determine whether older people at risk of falling demonstrate an impaired ability to stabilize the body under challenging conditions. METHODS: One hundred community-dwelling older people aged between 75 and 93 years were evaluated for their risk of falling using a range of physiological tests previously found to be accurate predictors of falling in prospective studies. Temporo-spatial gait parameters and acceleration patterns at the head and pelvis were then measured in three orthogonal planes while subjects walked on a flat corridor and an unpredictably irregular walkway. Harmonic ratios of head and pelvis accelerations in each plane were calculated to provide an indicator of stability. RESULTS: Subjects with a high risk of falling exhibited reduced temporo-spatial gait parameters and increased step timing variability. Harmonic ratios of acceleration patterns were reduced at the head and pelvis in the vertical and antero-posterior directions. These differences were particularly evident when walking on the irregular surface. CONCLUSION: Older people at risk of falling adopt a more conservative basic walking pattern, but this does not ensure that the movements of the head and pelvis are stable. The irregular pelvis and head accelerations evident in the high risk group suggests that these subjects may have difficulty controlling trunk motion and maintaining a stable visual field when walking, particularly on irregular terrain.

Acceleration↗

Chest wall acceleration and force measurements in simulated manual and mechanical cardiopulmonary resuscitation.

During CPR, the dynamics of the chest compression process play a major role in determining the outcome of the resuscitation effort. To quantify chest wall motion during CPR, a number of important variables must be determined, including maximum downward acceleration and velocity of the chest wall, time during which the wall is held in compression, and maximum depth and rate of chest compression. In this study, miniature accelerometers were used to record chest wall motion during simulated CPR with standard training manikins. One series of CPR tests included force measurements from a three-dimensional force platform placed under the manikin. The results of this investigation showed that American Heart Association (AHA)-certified rescuers are able to produce a consistent pattern of chest wall displacement during a manikin training exercise, and only small differences in displacement recordings are found when comparing one certified rescuer to another. Any given rescuer will usually generate a consistently repeatable acceleration pattern during CPR. However, these cyclical acceleration patterns differ markedly when comparing different certified rescuers. Mechanical CPR with a standard device produced larger peak accelerations than manual CPR. However, the maximum downward velocity was usually higher with manual CPR. In comparison with trained but clinically inexperienced individuals, rescuers with extensive in hospital experience produced relatively larger downward accelerations, longer "hold" times with the chest in compression, and maximum chest displacements that exceeded the current AHA recommendations. Measurements of the force transmitted through the manikin to a force platform clearly indicated the presence of a "hold" phase (if present) and the existence of large force components in the horizontal plane.

Acceleration↗

The Stanford Linear Accelerator Center pulsed x-ray facility.

The Stanford Linear Accelerator Center (SLAC) operates a high-energy (up to 33 GeV) linear accelerator delivering pulses up to a few microseconds wide. The pulsed nature of the electron beam creates problems in the detection and measurement of radiation both from the accelerator beam and the klystrons that provide the radio-frequency power for the accelerator. Hence, a pulsed x-ray facility has been built at SLAC mainly for testing the response of different radiation detection instruments to pulsed radiation fields. The x-ray tube consists of an electron gun with a control grid. This provides a stream of pulsed electrons that can be accelerated towards a confined target window. The window consists of Al 0.051 cm (20 mils) thick, plated on the vacuum side with a layer of Au 0.0006 cm (1/4 mil) thick. The frequency of electron pulses can be varied by an internal pulser from 60 to 360 pulses per second with pulse widths of 360 ns to 5 microseconds. The pulse amplitude can be varied over a wide range of currents. An external pulser can be used to obtain other frequencies or special pulse shapes. The voltage across the gun can be varied from 0 to 100 kV. The maximum absorbed dose rate obtained at 6.35 cm below the target window as measured by an ionization chamber is 258 Gy/h. The major part of the x-ray tube is enclosed in a large walk-in cabinet made of 1.9-cm-thick (3/4-inch-thick) plywood and lined with 0.32-cm-thick (1/8-inch-thick) Pb to make a very versatile facility.

Electrons↗

A radiation accident at an industrial accelerator facility.

On 11 December 1991, a radiation overexposure occurred at an industrial radiation facility in Maryland. The radiation source was a 3-MV potential drop accelerator designed to produce high electron beam currents for materials-processing applications. This accelerator is capable of producing a 25 milliampere swept electron beam that is scanned over a width of 112.5 cm and which emerges from the accelerator vacuum system through a titanium double window assembly. During maintenance on the lower window pressure plate, an operator placed his hands, head, and feet in the beam. This was done with the filament voltage of the electron source turned "off," but with the full accelerating potential on the high voltage terminal. The operator's body, especially his extremities and head, were exposed to electron dark current. In an attempt to reconstruct the accident, radiochromic film and alanine measurements were made with the accelerator operated at two beam currents. Measured dose rates ranged from approximately 40 cGy s-1 inside the victim's shoe to 1,300 cGy s-1 at the hand position. Approximately 3 mo after the accident, it was necessary to amputate the four digits of the victim's right hand and most of the four digits of his left hand. Electron paramagnetic resonance spectrometry, which measures the concentration of radiation-induced paramagnetic centers in calcified tissues, was used to estimate the dose to the victim's extremities. A mean dose estimate of 55.0 +/- 3.5 Gy (95% confidence level) averaged over the mass of the bone was obtained for the victim's left middle finger (middle phalanx).

Accidents, Occupational↗

Analysis of real-time head accelerations in collegiate football players.

OBJECTIVE: To measure and analyze head accelerations during American collegiate football practices and games. METHODS: A newly developed in-helmet 6-accelerometer system that transmits data via radio frequency to a sideline receiver and laptop computer system was implemented. From the data transfer of these accelerometer traces, the sideline staff has real-time data including the head acceleration, the head injury criteria value, the severity index value, and the impact location. Data are presented for instrumented players for the entire 2003 football season, including practices and games. SETTING: American collegiate football. SUBJECTS: Thirty-eight players from Virginia Tech's varsity football team. MAIN OUTCOME MEASUREMENTS: Accelerations and pathomechanics of head impacts. RESULTS: : A total of 3312 impacts were recorded over 35 practices and 10 games for 38 players. The average peak head acceleration, Gadd Severity Index, and Head Injury Criteria were 32 g +/- 25 g, 36 g +/- 91 g, and 26 g +/- 64 g, respectively. One concussive event was observed with a peak acceleration of 81 g, a 267 Gadd Severity Index, and 200 Head Injury Criteria. Because the concussion was not reported until the day after of the event, a retrospective diagnosis based on his history and clinical evaluation suggested a mild concussion. CONCLUSIONS: The primary finding of this study is that the helmet-mounted accelerometer system proved effective at collecting thousands of head impact events and providing contemporaneous head impact parameters that can be integrated with existing clinical evaluation techniques.

Acceleration↗

In vitro evaluation of a sensor sensitive to acceleration forces included in a new rate modulated pacemaker.

UNLABELLED: The characteristics of the sensor and rate adaptive algorithm included in a new dual chamber rate responsive pacemaker (Relay 294-03, Intermedics, Inc.) were studied by submitting the device to calibrated to-and-fro movements of specific frequencies and peak accelerations by means of a mechanical arm connected to a speed adapter. Atrial pacing rate was continuously recorded on a Holter monitor. The influences of the frequency, the magnitude, and the axis of the acceleration forces as well as the reproducibility of the rate response were evaluated. RESULTS: (1) The sensor was sensitive to frequencies ranging from 0.5 to 7 Hz with a peak sensitivity at 3 Hz; (2) the pacing rate was not affected during movements at frequencies > 6 Hz, commonly presented as nonactivity related signals (car, bus transportation, drilling....); (3) the pacing rate increased as a function of the acceleration magnitude up to 0.5 G (0.3 G for 3 Hz), then remained constant. This level of acceleration usually corresponds to high degrees of activity; (4) rate response was maximum when acceleration was directed in the anteroposterior direction; (5) reproducibility of the rate response was excellent (R2: 0.999; slope of the regression line: 0.999). CONCLUSION: Relay 294-03 is a low frequency signal sensing rate modulated pacemaker using an accelerometer sensitive to motion, mainly in the anteroposterior direction.

Acceleration↗

Experimental brain damage from fluid pressures due to impact acceleration. 1. Design of experimental procedure.

The significance of the intracranial acceleration pressure pattern at impact to the intact skull in production of brain damage is discussed particularly as regards the contre-coup pressures. Sudden pressure changes within the cranial cavity of the rabbit were studied by means of a new impact acceleration model. The rabbit skull was connected with a cylinder. Impact acceleration was applied to the model with the skull contents serving as a "contre-coup end". Skull deformation was minimized by reinforcement of the skull vault. Acceleration, velocity and displacement of the system were recorded at various sites and could be predicted within wide ranges. Simultaneous recordings were also made of the pressure changes in the skull cavity and cylinder contents. By adjusting the acceleration course and by introducing a quantified air bubble 050, 100, 150 mm3) at the impact of the cylinder, it was possible to produce and vary an intracranial pressure pattern of "contre-coup type", including predictable subatmospheric transients. The mechanics of the intracranial pressure changes and displacements are discussed. The method seems to be suitable for studying the relations between brief negative-positive pressure variations (about 5 ms) of "contre-coup type" and pathological alterations similar to those reported in other head injury models and in human head trauma.

Acceleration↗

Monte Carlo study of photon fields from a flattening filter-free clinical accelerator.

In conventional clinical linear accelerators, the flattening filter scatters and absorbs a large fraction of primary photons. Increasing the beam-on time, which also increases the out-of-field exposure to patients, compensates for the reduction in photon fluence. In recent years, intensity modulated radiation therapy has been introduced, yielding better dose distributions than conventional three-dimensional conformal therapy. The drawback of this method is the further increase in beam-on time. An accelerator with the flattening filter removed, which would increase photon fluence greatly, could deliver considerably higher dose rates. The objective of the present study is to investigate the dosimetric properties of 6 and 18 MV photon beams from an accelerator without a flattening filter. The dosimetric data were generated using the Monte Carlo programs BEAMnrc and DOSXYZnrc. The accelerator model was based on the Varian Clinac 2100 design. We compared depth doses, dose rates, lateral profiles, doses outside collimation, total and collimator scatter factors for an accelerator with and without a flatteneing filter. The study showed that removing the filter increased the dose rate on the central axis by a factor of 2.31 (6 MV) and 5.45 (18 MV) at a given target current. Because the flattening filter is a major source of head scatter photons, its removal from the beam line could reduce the out-of-field dose.

Computer Simulation↗