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PubMed1989

The effect of abortion on the incidence of pre-eclampsia.

The incidence of pre-eclampsia was studied in 9771 women that were pregnant for the first or second time. The protection offered by a previous pregnancy which ended in abortion was compared to that provided by a first pregnancy that proceeded to term. The rate of pre-eclampsia was 2.9% for primigravid women and was significantly lower (1.5%, p less than 0.001) for women giving birth for the second time. Adjusting by multiple regression for confounding factors (e.g., maternal age, social class, ethnic origin and smoking), the incidence of pre-eclampsia was also significantly lower (p = 0.038) following an induced abortion, but not following a spontaneous abortion.

Abortion, Induced↗

PubMed1983

Effects of abortion on subsequent pregnancies.

The loss of a very precious pregnancy in abortion could affect both the health of the patient and the outcome of her subsequent pregnancies. In a study of the outcome of the pregnancies that immediately follow an abortion, it was found that among women who had D&C to induce abortions in their previous pregnancies a higher incidence of abortion was found, and that these may be due to possible damage to the cervix, resulting from forcible dilatation of the cervix during the operation. It was also found, however, that a higher percentage of those who had abortions after 16 weeks in the previous pregnancies had premature deliveries in the current pregnancies. It was suggested that this may be attributable to cervical incompetence, although congenital or functional defects of the cervix may be contributory.

Abortion, Induced↗

PubMed1987

Effects of treatment on fertility in long-term survivors of childhood or adolescent cancer.

In a retrospective cohort study of survivors of cancer and of controls, we estimated the risk of infertility after treatment for cancer during childhood or adolescence. We interviewed 2283 long-term survivors of childhood or adolescent cancer diagnosed in the period from 1945 through 1975, who were identified at five cancer centers in the United States. Requirements for admission to the study were diagnosis before the age of 20, survival for at least five years, and attainment of the age of 21. In addition, 3270 controls selected from among the survivors' siblings were interviewed. Cox regression analysis showed that cancer survivors who married and were presumed to be at risk of pregnancy were less likely than their sibling controls to have ever begun a pregnancy (relative fertility, 0.85; 95 percent confidence interval, 0.78 to 0.92). Radiation therapy directed below the diaphragm depressed fertility in both sexes by about 25 percent. Chemotherapy with alkylating agents, with or without radiation to sites below the diaphragm, was associated with a fertility deficit of about 60 percent in the men. Among the women, there was no apparent effect of alkylating-agent therapy administered alone (relative fertility, 1.02) and only a moderate fertility deficit when alkylating-agent therapy was combined with radiation below the diaphragm (relative fertility, 0.81). Relative fertility in the survivors varied considerably according to sex, site of cancer, and type of treatment; these factors should be taken into consideration in counseling survivors about the long-term consequences of disease.

Adolescent↗

PubMed1996

Psychological long-term effects of sterilization on anxiety and depression.

Two-thousand cases (500 women and 500 men with sterilization; 500 women and 500 men without sterilization) in two counties and two cities in Sichuan, China, were investigated between 15 September 1992 and 30 April 1993. Information was obtained about their age, parity, marriage, contraceptives, social behavior, and present psychological characteristics. CES-D, SAS, and E.P.Q. scales were used to assess the depressive symptomatology, anxiety, and personality of the subjects. The results revealed that sterilization psychologically affected the depressive symptoms and anxiety under the neutral personality. In addition, depressive symptoms and anxiety were related to the subjects' age, educational level, income, operative doctors' attitudes to sterilization acceptors, and subjects' understanding of the sterilization.

Adult↗

PubMed1987

Economic instability, unemployment rates, behavioral risks, and mortality rates in Scotland, 1952-1983.

Short-term relations (under five years) between national unemployment and cause-specific mortality rates have been found in several industrialized countries in Europe and North America including the United States and, separately, Scotland and England/Wales. Long-term cumulative relations (at least a decade) have been found between national unemployment and age-adjusted mortality rates for eight countries including England/Wales. In this article it is demonstrated that, controlling for the significant effects of per capita cigarette, spirits, and fat consumption, and cold winter temperatures, there is in Scotland a significant long-term relation (at least a decade) between cumulative change in unemployment rates and mortality rates-for all causes, for total heart disease, and in particular for ischemic heart disease. Also, the exponential trend in real per capita income is related to mortality declines. Other writers have encountered difficulty in measuring this long-term relation between unemployment and cause-specific mortality in Scotland in the absence of controls for at least alcohol and tobacco consumption per capita.

Alcohol Drinking↗

PubMed1992

The global epidemiology of the HIV/AIDS pandemic and its projected demographic impact in Africa.

The global epidemiology of HIV/AIDS has evolved to the point that the pandemic now predominantly affects heterosexuals, especially in developing countries. This article summarizes the status of the HIV/AIDS pandemic as of the early 1990s; provides estimates and short-term projections of AIDS mortality in a hypothetical country of sub-Saharan Africa; projects the potential demographic impact of AIDS in a hypothetical sub-Saharan country; and describes the major problems associated with modelling the long-term demographic impact of this pandemic. Estimated AIDS cases and deaths up to 1992 were extrapolated from public health surveillance data and through use of the WHO model. Estimates of HIV seroprevalence were based on available HIV serological data. For developed countries, HIV estimates developed by national experts and/or national AIDS programmes were used, and for developing countries estimates by regional experts were used or were prepared by WHO. For the first half of the 1990s, projections of AIDS cases and deaths were derived from the WHO model; beyond the mid-1990s, the potential effects of AIDS on selected demographic indicators were derived from a demographic projection model developed by the World Bank. Although estimates and long-term projections cannot be made with great precision, the general dimensions of the HIV/AIDS pandemic have been more clearly delineated now at the start of its second decade. Epidemiological data indicate that in industrialized countries, where extensive spread of HIV began in the late 1970s or early 1980s, the majority of HIV infections occurred during the first half of the 1980s.(ABSTRACT TRUNCATED AT 250 WORDS)

Acquired Immunodeficiency Syndrome↗

PubMed1994

Long-run migration incentives and migration effects: the case of different fertility rates.

"In this paper the direction of the long-run migration incentive in the presence of closed borders and the long-run welfare effects of a regime change from 'autarky' to 'free permanent migration' are studied. A difference in birth-country specific fertility rates is treated as the final cause for the creation of migration incentives in a two-country model where the standard overlapping-generations framework is used.... Opening the borders for permanent migration can always lead to the equalization of labour force growth rates. A continuum of such equilibria with migration does exist, but the application of the concept of migration-stability, introduced in this paper, gives reason to the suspicion that free migration can also lead to a collapse of the emigration country's economy." (SUMMARY IN GER)

Demography↗

PubMed1991

The impact of the Gulf war on migration and remittances in Asia and the Middle East.

The author discusses the impact of the 1990 Gulf war on the migrant worker populations in the region, with a focus on migration and remittances in Asia and the Middle East. Both immediate and long-term effects are considered. "From the perspective of foreign migrant communities living in the Gulf...the war...was much more of a disaster for Arabs than for Asians....Arab migrant populations...were dramatically affected by the Gulf crisis. In contrast, the Asian migrant community was largely concentrated in Saudi Arabia and the [United Arab Emirates] and remained relatively less affected by the crisis. Subsequent polarization in the Arab world gives Asian labor-exporting countries an unexpected opportunity to increase their share of Gulf labor markets still further in the coming years." (SUMMARY IN FRE AND SPA)

Asia↗

PubMed1981

Epidemiologic detection of low dose effects on the developing fetus.

Evaluations of the health effects of exposures in the workplace and environment have broadened to include effects on reproduction, as well as on the development of cancer. Models to assess risks associated with varying doses of exposure rest almost entirely on data about cancer. In this paper we discuss some distinctive features of reproduction which bear on the interpretation of such models, when applied to reproduction, rather than carcinogenesis. Dose-response curves describe the relationship between two exposures (smoking and alcohol drinking) and two outcomes (spontaneous abortion and birthweight) are used to illustrate some of the questions which arise in attempting to determine a "safe" level of exposure.

Abortion, Spontaneous↗

PubMed1984

Long-term follow-up of children breast-fed by mothers receiving depot-medroxyprogesterone acetate.

A long-term follow-up study compared development and health of 128 breast-fed children whose mothers had received depot-medroxyprogesterone acetate (depot-MPA) while lactating and 142 control children whose mothers had used mechanical contraceptives or no contraceptives or had undergone sterilization. The children, who were approximately 4-1/2 years old at follow-up, showed no ill effects on their growth and development and health status from exposure to depot-MPA. Depot-MPA-treated mothers lactated significantly longer than controls and also had greater parity than controls. These factors apparently contributed to a difference in weight at follow-up. Compared with the Sempe-Pedron standard, more of the depot-MPA group were underweight and more controls were overweight.

Adult↗

PubMedDate not supplied

Evaluating the impact of a theory-based sexuality and contraceptive education program.

A controlled field study involving 1,444 adolescent males and females 13-19 years of age was performed to compare a sexuality education program based on the health belief model and social learning theory with several publicly funded community-based and school-based interventions. Among males who had never had intercourse prior to participating in the study, those in the experimental program were more likely than those in the comparison programs to maintain abstinence over the next year; there was no program effect, however, among females. Among female adolescents who initiated intercourse after the start of the study, attendees of the comparison programs were more likely to have used an effective contraceptive at most recent intercourse and to have used an effective method more consistently than were those who attended the experimental program; no such association was seen among comparable young men. Both experimental and comparison programs significantly increased the consistent use of effective methods among teenagers who had been coitally active before attending the programs. Among males, however, when preintervention contraceptive efficiency was held constant, the experimental program led to significantly greater contraceptive efficiency during the follow-up year than did the comparison programs; among females, the two approaches produced an equivalent degree of improvement. Finally, prior exposure to sexuality education was associated with greater contraceptive efficiency at the one-year follow-up among almost all sexual-experience and gender groups, regardless of the type of intervention program attended.

Adolescent↗

PubMed1988

Smoking in pregnancy and development into early adulthood.

Follow up analyses of data on the 1958 cohort from the national child development study have shown that the association of smoking in pregnancy with physical and intellectual development diverges between the sexes at age 16, no longer being significantly associated with height in girls. These studies, however, have emphasised that the differences in outcome are small and may be explained by other factors. The analyses have taken account of birth weight and have therefore examined the effects of smoking on subsequent development in addition to this variable. To assess the importance of smoking on development in early adult life and whether the effect is independent of birth weight data from the 1958 cohort at age 23 were analysed. Only weak evidence for a relation between smoking in pregnancy and self reported height of the offspring was apparent once social class, size of family, mothers' height, and birth weight for gestational age were taken into account. After omission of birth weight from the analyses, however, the average difference in height between subjects whose mothers smoked 20 cigarettes a day or more during the second half of pregnancy and those whose mothers did not was 0.93 cm in men and 1.83 cm in women. A strong association was also evident with the highest qualification achieved by subjects at this age, suggesting a long term relation between smoking in pregnancy and the intellectual development of the offspring.

Adult↗

PubMed1981

A two-year follow-up study of women sterilized in India.

For large-scale program implementation, it is important to document both early and long-term safety and effectiveness of female sterilization methods. The results of this controlled, prospective, two-year study of 2,053 women who underwent sterilization in Baroda, India, show a marked decline in gynecological abnormalities over time; the incidence of gynecological pathology following sterilization was not significantly higher than what might be expected in the general population. The incidence of post-sterilization gynecological surgery was low. Significantly more women had weight gain than weight loss after sterilization. After sterilization, no change in menstrual cycle parameters was reported for the vast majority of women. Both favorable and unfavorable changes in menstrual cycle parameters were noted. The one-year and two-year pregnancy rates were 0.0 and 0.4 percent, respectively. No ectopic pregnancies were reported.

Body Weight↗

PubMed1995

Total hip arthroplasty in patients with ankylosing spondylitis: longterm followup.

OBJECTIVE: To evaluate the longterm functional effects of total hip arthroplasty (THA) on 46 patients. METHODS: Clinical and radiographic examinations were performed on 46 patients (74 THA) with ankylosing spondylitis (AS). The mean followup period was 100 months (range 37-174 months); 32 hips were followed for more than 10 years. RESULTS: Significant benefit was obtained in pain control (all but 2) and function (mean improvement in range of motion 128 degrees) in the early stage so that patients could be gainfully employed. An average 100 months after THA, the overall functional results were rated excellent in 21 hips, good in 28, fair in 7, and poor in 18. Only 6 hips (8%) in our series developed clinically significant (Class III or IV) heterotopic ossification. Seventeen hips needed a 2nd operation because of loosening (11 hips), deep infection (3), malposition of acetabular component (2), and prosthetic failure (1). Another 6 hips showed definite loosening on radiographs and needed to be revised. The total incidence of failure was 31% (23 hips). The average time from the index operation to loosening was 9.5 years (range 4-13 years). Factors contributing to component loosening were young age, short stature, and decreased postoperative range of motion. CONCLUSION: Total hip arthroplasty can be very important and beneficial to patients with AS, but the patients, being young and active, and with their rigid spines, do not treat their prostheses gently and are very dependent upon their mobility. They must be kept under supervision long after THA, probably for the rest of their lives, to identify possible longterm complications.

Adult↗

PubMed1987

Effects of induced abortion on the third stage of labor in subsequent pregnancy.

The aim of the study was to investigate whether the expulsion of the placenta was delayed among women who had previously undergone induced abortion by suction curettage. We studied the duration of the third stage of labor retrospectively by comparing the third stage of labor, recorded in minutes, between 76 second gravida women with previously induced abortions and 95 second para women with previously uncomplicated pregnancies. The duration of the third stage of labor was also compared among a group of primigravidas and a group of second gravidas with previously induced abortions. We excluded women with previous gynecological disorders (e.g. resulting in curettage of the uterine cavity). All patients included presented normal pregnancies and deliveries resulting in full term (greater than 37 weeks), liveborn infants. By the statistical analysis (analysis of variance and Duncan's test), it could be shown that the 3rd stage of labor lasted significantly longer among women with previously induced abortions (mean: 12 minutes), than among the other groups included in the study (mean: 9 minutes). This discrete difference in length of the third stage of labor need not indicate an altered routine for women, who give birth subsequent to an induced abortion.

Abortion, Induced↗

PubMed1990

Late luteal administration of the antiprogesterone RU486 in normal women: effects on the menstrual cycle events and fertility control in a long-term study.

Twelve regularly cycling women, with contraindications to other methods of contraception, received RU486 (Roussel UCLAF, Romainville, France), once a month as a method of fertility control. The study was designed for 18 consecutive cycles. Each patient recorded basal body temperature, detected urinary luteinizing hormone peak, and collected saliva samples during each luteal phase for progesterone (P) determinations. A single dose of RU486, 600 mg, was given on the day before the expected date of the menses and 8 days later in case of continuing pregnancy after the first dose. Blood samples were collected for estradiol, P, and beta-human chorionic gonadotropin analyses on these two occasions. The compliance was poor and the results of only 137 cycles were obtained. The menstrual cyclicity was not significantly modified during this long-term study. Of the 137 cycles, 22 pregnancies occurred (16%), and 4 (18.2%) were not interrupted by the second dose of RU486. Thus, because of the high failure rate, use of RU486 at the time of the natural P withdrawal cannot be advocated as a "once-a-month" contragestive agent.

Adult↗

PubMed1988

City size, quality of life, and the urbanization deflator of the GNP: 1910-1984.

The authors attempt to determine the net effect of city size on quality of life by developing a welfare measure of urbanization. "The estimation procedure suggested in the theoretical part of the paper (section II) is implemented in the empirical part (section III) using 1980 census data from the [U.S.] PUMS (Public Use Micro Data Sample). The results indicate there is no single optimal city size, but rather a worst city size, and about 90 percent of the U.S. population reside in cities smaller than worst city size. If quality of life is related to the degree of urbanization, then long-term trends in the locational distribution of the population should be accounted for in any welfare-oriented measure of national income. One application of our results is, as indicated, the derivation of a GNP welfare deflator reflecting changes in the degree of urbanization (section IV). The findings suggest an urban deflator on the order of six to seven percentage points, which is steadily increasing at a rate of about half a percentage point per decade."

Americas↗

PubMed1996

The floating population: an informal process of urbanisation in China.

"This paper attempts to employ substantial source materials to shed light on the characteristics of population migration in a centrally planned society that is in the process of transforming to a market economy. In order to compare rural-urban migration in China with that in other developing countries, the data on 1985-1990 interprovincial population migration have been analysed. Some demographic research techniques on population migration, such as the impact on the place of origin and the place of destination, have been employed to assess the influence of rural-urban migration on China's long-term economic development. Economic betterment appears to be the sole motivation of rural population migration in China."

Asia↗