PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Mastectomy, Simple”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 487 records · Page 27Linked to original sources
PubMed1979

[Therapy of breast cancer. Results and prognosis after treatment with different surgical methods].

Breast carcinoma is the most frequent form of cancer in women. In Switzerland 1265 women died of it in 1975, the mortality rate is rising slowly, the cause of this being unclear. There is no uniformity about the best treatment of breast cancer. We analyzed 454 carcinomas, operated in the years 1961--1971 according to Halsted, Patey and McWhirter. We found similar 5- and 10-year survival rates with the Halsted and the Patey method of operation, however, decidedly worse results with the simple mastectomy. Today we recommend the modified radical excision of the breast after Patey at all stages; in addition we treat all patients with postoperative X-ray therapy or prescribe an adjuvant cytostatic therapy based on the experimental study of the SAKK (Swis Therapy Group for Clincal Cancer Research).

Breast Neoplasms↗
PubMed1979

[Breast cancer in males].

Until 1971 13 cases of breast cancer in men were observed in our service. In the world literature it accounts for 1% of all cancer of the breast; in our series we have found 4% of all breast cancer. Men present themselves for treatment later and with more advanced local signs than women. In our series, the greatest number of cases occurs near the seventies in men, which is about twenty years later than in women. The etiology is remained unknown, but Klinefelter's disease seems to be a risk for breast cancer. If there are no metastasis, we prefer in our service the surgical treatment as unique treatment. If possible the operation of Patey is realised, but sometimes we have to do a simple mastectomy only as a safe alternative for poor risk patient. In case of metastatic breast cancer the adjuvant treatment was X-ray therapy, chemotherapy and in some of our cases hormonotherapy. We do not have any experience with suppressive hormonal therapy such as orchiectomy or adrenalectomy. Most of the authors think that prognosis of breast cancer in males is worse than in women; the constant central localization of the tumour may be an explanation for that. The fate of women with central lesions is as poor as in males.

Aged↗
PubMed1970

Therapy of primary breast cancer.

Most breast cancers are multicentric in origin. They drain into two primary lymphatic depots-the axilla and internal mammary chain of nodes. The incidence of metastasis to the internal mammary nodes rises as the location of the primary tumor approaches to the sternal margin of the breast. One hundred and thirty-seven patients primarily with in situ and non-infiltrating intraductal carcinoma were treated adequately by simple mastectomy and axillary dissection with preservation of the pectoral muscles. All have remained free of disease. Infiltrating cancers arising in the lateral portion of the breast are best treated by radical mastectomy since they spread mainly to the axillary nodes. Medial and central infiltrating cancers have been treated by radical mastectomy with internal mammary resection, since they show a higher incidence of internal mammary metastasis. Seventy-two percent of 500 patients treated in this fashion survived at five years and 65 percent were clinically free of disease. A five-year salvage rate of 60 percent and a ten-year salvage rate of 50 percent were obtained in patients with only internal mammary node metastasis or in those with only axillary involvement. When both nodal areas were involved 43 percent remained free of disease at five years and 20 percent at ten years. Mammography and biopsy of the contralateral breast at the time of radical mastectomy contributed to the detection of early localized breast cancer.

Biopsy↗
PubMed1977

Angiosarcoma of the breast.

The authors report a case of angiosarcoma of the breast. The patient, a 44-year-old woman, remains free of disease 7 years after biopsy and 6 years after a simple mastectomy. The authors emphasize the benign appearance of the tumour and the importance of early detection and adequate surgical treatment.

Adult↗
PubMed1978

[Prognosis with different therapeutic methods and therapeutic recommendations in operable breast cancers].

Breast carcinoma is the most frequent form of cancer in women. In Switzerland 1265 women died of it in 1975, the mortality rate is rising slowly, the cause of this fact being unclear. There is no uniformity about the best treatment of breast cancer. We analyzed 454 carcinomas, operated in the years 1961--1971 after Halsted, Patey and McWhirter. We found similar 5- and 10-year survival rates with the Halsted and the Patey method of operation, however, decidedly worse results with the simple mastectomy. Nowadays we recommend the modified radical excision of the breast after Patey at all stages; in addition we treat all patients with postoperative X-ray therapy or prescribe an adjuvant cytostatic therapy based on the experimental study of the SAKK (Swiss Therapy Group for Clinical Cancer Research).

Adolescent↗
PubMed1981

[The problem of cysto-sarcoma phyllodes (author's transl)].

Problems in the diagnosis and treatment of cysto-sarcoma phyllodes in thirteen women are discussed. This is a rare breast tumour which must be regarded as semi-malignant. Its malignancy consists of its tendency to recurrence and the development of distant metastases. Five patients had one or more recurrences and three patients had metastases which were fatal. Radiological and thermographic diagnosis of small tumours is unreliable. It is not possible to distinguish the benign from the malignant variants. Accurate classification depends on histological examination. The authors consider removal of the glandular tissue or simple mastectomy to be the best form of treatment.

Adolescent↗
PubMedDate not supplied

Cystosarcoma phyllodes.

A series of 27 cystosarcoma phyllodes diagnosed in 23 patients is presented. Treatment consisted of wide local excision with a rim of normal tissue for the histologically benign-appearing tumors, and simple mastectomy for the histologically malignant-appearing tumors. Of the three tumors with a malignant appearance, one metastasized distantly and the patient died; the other two patients were apparently cured. Of the 24 benign-appearing tumors, 3 recurred locally and were cured by reexcision. None behaved in a malignant fashion. There was one case of bilateral cystosarcoma phyllodes, and one tumor was associated with carcinoma of the breast. The local recurrence rate of 11% (3 out of 27) and mortality rate of 4% (1 out of 23) appears to justify this therapeutic approach. The precise indications for mastectomy in this disease are still unclear.

Adolescent↗
PubMed1984

[Angiosarcoma of the breast].

A painless ecchymotic plaque developed progressively on the right breast of a 16 years old girl. Failure of the first biopsies to bring up specific lesions and episodes of regression delayed the diagnosis until a very deep biopsy and a CT-scan investigation revealed a diffuse and malignant vascular process. A simple mastectomy did not prevent recurrence and metastasing 3 months later. The clinical aspects of breast angiosarcoma, the shortcomings of investigative procedures and the recommended therapeutics are reviewed.

Adolescent↗
PubMed1984

[Results of standardized postoperative radiotherapy in circumscribed breast cancer. A retrospective study of 432 patients].

From 1970 through 1981 232 women with breast cancer (190 with T1 N0 M0 and 242 with T2 N0 M0 disease) received postoperative radiotherapy . The usual surgical procedure was simple mastectomy with axillary lymph node dissection. The chest wall was irradiated using 137Caesium up to 40 Gy, while supraclavicular, infraclavicular and axillary lymph node areas were irradiated using 5,7 MeV photons up to 45 Gy. The rate of local recurrence was 2,4% and 3,3% in stage T1 and T2 respectively. The corresponding projected ten-year-survival was 88% and 78%, respectively. These data and results obtained by others may strengthen the grounds for recommending conservative surgical approaches in early stage breast cancer, in combination with tumoricidal radiotherapy, individualized according to the anatomic tumor site.

Adenocarcinoma↗
PubMed1983

[Therapeutic breast-preserving measures in operable breast carcinoma].

Simple mastectomy with axillary clearance represents the standard therapy in operable breast cancer. In many cases no additional complex therapeutic measures have to be taken. For small tumors without clinical suspicion of lymphnode involvement in the axilla a combination of tumorectomy and axillary clearance followed by high voltage radiotherapy allows the conservation of a nearly normal breast. The survival figures available today show no difference between amputation and conservative treatment. An absolute condition for successful conservative treatment and follow-up is a consequent and continuous collaboration between the involved disciplines. If this is not the case, mastectomy with eventual later reconstruction has to be preferred.

Breast Neoplasms↗
PubMed1980

[Treatment of breast cancer in aged women].

The AA. consider the problem of mammary cancer in the woman more than 70 years old. The incidence of this tumor is about 30% and therefore it is necessary an exact start of therapy. For the AA. the therapy must base itself essentially on a good locoregional treatment, that comes from the constant association of simple mastectomy, if possible with axillary curage, with radiant therapy with small dosages and for a long time, in case with alternate ranges. The systemic treatment must base itself fundamentally and only on an aspecific immunotherapy that can be begun very early and on an hormonal therapy. This hormonal therapy should be suggested, where is possible, by the results of hormonal dosage on plasma and urine.

Aged↗
PubMed1981

Submuscular breast reconstruction--indications and techniques.

We review the care and treatment of 93 patients who underwent submuscular breast reconstruction in our service between 1975 and 1980. The indications and clinical situations in which submuscular reconstruction has been useful include: following simple mastectomy; following modified radical mastectomy; following subcutaneous mastectomy (immediate or delayed reconstruction); in standard augmentation mammaplasty in selected patients; and with unusual, unsatisfactory, or dangerous preexisting breast conditions. Unusual indications include unsatisfactory subcutaneous placement with capsule formation after subcutaneous mastectomy; use of unsatisfactory or dangerous implants such as Ivalon and Etheron; and replacement of the old-fashioned Cronin gel implants with fixation patches. Submuscular placement has also been used to advantage in patients with excessively scarred, tenuous skin. Technical modifications in the submuscular implantation technique are detailed. We have used subserratus-subpectoral placement in most instances. Technical tips to keep the implant in a low position by division of the serratus attachments and limitations of upward dissection are detailed. Clinical studies on the upward migration of implants and pressures developed under the serratus and pectoralis muscles as measured by manometer are also detailed.

Breast↗
PubMed1981

Coumadin-induced breast necrosis.

A case of coumadin necrosis of the breast is presented. Most patients with this entity are obese, middle-aged females who have been treated with oral anticoagulants for three to five days for thrombophlebitis or peripheral arterial embolization. The key to therapy is early diagnosis and clinical differentiation from subcutaneous hemorrhage--a disease which is self-limited, nonprogressive, and treatable when anticoagulant therapy is either discontinued or reversed with vitamin K. Surgical debridement or simple mastectomy is generally necessary in those cases where necrosis is present.

Breast Diseases↗
PubMed1995

Tuberculosis of the breast.

OBJECTIVE: To present our 20 years experience of tuberculosis of the breast. DESIGN: Retrospective study. SETTING: Teaching hospital, Turkey. SUBJECTS: 9 women with tuberculous mastitis. MAIN OUTCOME MEASURE: Cure. RESULTS: All cases underwent frozen section and excision. One required a simple mastectomy because of the extent of destruction; the remainder underwent lumpectomy. All patients were given rifampicin, ethambutol, and isoniazid, and the three who had tuberculosis of other organs were also treated with streptomycin. Mean follow up was 87 months (range 6-178) and two patients were lost to follow up, at three and six years, respectively. Histological examination showed the presence of tubercle and central caseation in 8 cases and granulomatous infiltration in one. CONCLUSION: Tuberculous mastitis is rare, and should be suspected in any woman with persistent breast abscesses and sinuses, particularly if she lives in an area from which tuberculosis has not been eradicated. Conservative surgery and antituberculous drugs are the treatment of choice.

Adult↗
PubMed1995

Geographic variation in rates of selected surgical procedures within Los Angeles County.

OBJECTIVE: We explore the contribution of income and ethnicity to geographic variation in utilization of surgical procedures. DATA SOURCES/STUDY SETTING: We assessed the use of eight procedures from 1986 through 1988 among residents of Los Angeles County using data from the California Discharge Dataset, the 1980 census, and other secondary sources. Procedures chosen for evaluation were coronary artery bypass grafting (CABG), coronary artery angioplasty, permanent pacemaker insertion, mastectomy, simple hysterectomy, transurethral prostate resection (TURP), carotid endarterectomy, and appendectomy. STUDY DESIGN: The amount of inter-zip code variation for each procedure was first measured using various estimates including the analysis of variance coefficient of variation (CVA). Population-weighted multivariate regression analysis was used to model variation in age- and gender-adjusted rates of procedure use among 236 residential zip codes. PRINCIPAL FINDINGS: Highest-variation procedures were coronary artery angioplasty (CVA = .392) and carotid endarterectomy (CVA = .374). The procedures with the lowest degree of variation were cardiac pacemaker implantation (CVA = .194) and hysterectomy (CVA = .195). Variation was significantly related to income (carotid endarterectomy) and either African American or Latino zip code ethnicity for all procedures except pacemaker implantation. For all procedures except appendectomy, the direction of the effect was toward fewer procedures with lower income. However, the effect of African American or Latino population ethnicity varied. CONCLUSIONS: In this large urban area both population ethnicity and socioeconomic status are significantly associated with the geographic utilization of selected surgical procedures.

Age Factors↗
PubMed1994

Invasive breast cancer. Surgical treatment alternatives.

It is now widely accepted that cancer of the breast is a systemic disease and that some patients will not be cured even with the most extensive local treatment. This acceptance has resulted in a more conservative approach and participation of the patient in treatment planning. A number of factors influence the definitive surgical treatment for breast cancer. Important considerations include the size and histology of the lesion, the skill and experience of the multidisciplinary team, and the wishes of the patient.

Axilla↗
PubMed1994

[Angiosarcoma of the breast].

Angiosarcoma of the breast is a rare but highly malignant neoplasm of vascular origin. The median survival in previously reported cases is 22 months. The treatment of choice is simple mastectomy. Although the value of irradiation or chemotherapy as the only form of treatment is limited, their role as adjuvant therapy should be explored. One case is presented and a review of the literature is made.

Breast Neoplasms↗