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Seeing depth in colour: more than just what meets the eyes.

Novel binocular depth illusions obtained from two-dimensional colour images are presented. It is demonstrated that the magnitude of these illusions is based on transverse chromatic aberration (TCA), however, the depth obtained cannot be observed unless specific conditions are met even if the TCA is present. Some form of perceptual organization occurring at and/or beyond the binocular fusion site of the brain, is required for some of these effects to occur. An example of a paradoxical finding leading to this conclusion is the observation that under some conditions the same colour can be perceived on separate depth planes while spatially adjacent colours from opposing ends of the visible spectrum (i.e. red and blue or green) can be perceived on the same depth plane simultaneously within the same image. Further, results show that some form of reference plane is required by the brain to use the colour induced disparity, without which, depth cannot be perceived even if the disparity information is present. This phenomenon is spatially tuned for medium to high frequency components and is still detectable under isoluminant conditions which would support the notion that it requires information from the parvocellular pathway. Binocular lustre and rivaldepth are ruled out as being significant factors in the effect. It is argued that this phenomenon represents an instance of global interactive processes induced by TCA while previous studies on chromostereopsis have concentrated on local aspects. Results of the present study may explain why under certain situations depth can be perceived in coloured images and not under other circumstances where TCA is still present.

Color Perception↗

Reversals of the colour-depth illusion explained by ocular chromatic aberration.

Although many colour-depth phenomena are predictable from the interocular difference in monocular chromatic diplopia caused by the eye's transverse chromatic aberration (TCA), several reports in the literature suggest that other factors may also be involved. To test the adequacy of the optical model under a variety of conditions, we have determined experimentally the effects of background colour on perceived monocular chromatic diplopia and perceived depth (chromostereopsis). A Macintosh colour monitor was used to present red, blue, and green test stimuli which were viewed monocularly or binocularly (haploscopically) through 1.78 mm artificial pupils. These apertures were displaced nasally and temporally from the visual axis under controlled conditions to induce a variable degree of TCA. Monocular chromatic diplopia and binocular chromostereopsis were measured for red and blue targets, and also for red and green targets, presented on either a black background or on a background which was composed of the sum of the targets' spectral composition (e.g. red and blue presented on magenta; red and green presented on yellow). In all cases, chromatic diplopia and chromostereopsis were found experimentally to reverse in sign with this change in background. Furthermore, we found that a given coloured target could be located in different depth planes within the same display when located on different background colours. These seemingly paradoxical results could nevertheless be explained by a simple model of optical TCA without the need to postulate additional factors or mechanisms.

Adult↗

Tilt and decentration of three-piece foldable high-refractive silicone and hydrophobic acrylic intraocular lenses with 6-mm optics in an intraindividual comparison.

PURPOSE: Intraindividual comparison of tilt and decentration of three-piece foldable intraocular lenses (IOLs) with 6-mm optics and different edge design and material. DESIGN: Prospective randomized study. METHODS: Twenty-five patients with senile cataract (group I) received a foldable silicone, sharp optic edge IOL in one eye and a silicone, rounded optic edge IOL in the other eye. Group II (n = 28) received the foldable silicone, sharp optic edge IOL in one eye and an acrylate, sharp optic edge IOL in the other eye. Scheimpflug photography was performed after the procedure with an anterior eye segment analysis system. Tilt and decentration of the IOL optic were measured 1 week, 6 months, and 12 months after the procedure. RESULTS: In group I, the foldable silicone, sharp optic edge IOL showed a mean optic tilt of 3.03 +/- 1.79 degrees and an optic decentration of 0.24 +/- 0.13 mm; the silicone, rounded optic edge IOL showed a tilt of 3.26 +/- 1.69 degrees and a decentration of 0.23 +/- 0.13 mm. In group II, the foldable silicone, sharp optic edge IOL showed an average tilt of 2.34 +/- 1.81 degrees and a decentration of 0.29 +/- 0.21 mm after 12 months; the acrylate, sharp optic edge IOL had a tilt of 2.32 +/- 1.41 degrees and a decentration of 0.24 +/- 0.10 mm. There were no significant differences in either group. CONCLUSION: The examined IOLs showed a stable position regarding tilt and decentration in the first 12 postoperative months, independent of material and edge design. Slight deviations from the optical axis might affect the outcome in aspheric or multifocal IOLs.

Acrylic Resins↗

"Bothersome blur": a functional unit of blur perception.

Knowledge regarding the amount of blur perceived to be "bothersome" to an individual, namely that which is assumed to be annoying and to adversely affect task performance, remains limited. A Badal optical system was used to measure the blur detection, bothersome blur, and non-resolvable blur dioptric thresholds monocularly either to an isolated 20/50 or 20/200 Snellen E, or to three 20/50 lines of text. Subjects were comprised of 13 visually normal young adults and 3 absolute presbyopes. Cycloplegia was used to paralyze accommodation in the young adults. Within each target type for the young adults, the mean bothersome blur threshold was always significantly larger than that found for blur detection and significantly smaller than that found for non-resolvable blur. Across target types and blur criteria, the bothersome blur thresholds for the isolated 20/50 E (1.02 D) and the 20/50 text (1.34 D) were not significantly different, although in 12 of the 13 subjects the latter were larger (p<0.002, sign test). However, both were significantly smaller than for the isolated 20/200 E (1.80 D). In a subset of young adult subjects, bothersome blur was found to be repeatable over time. The results were similar in the absolute presbyopes. The bothersome blur threshold was primarily influenced by target detail and secondarily by target extent. These findings have important implications with respect to tolerances for optical lens design and refractive surgery outcomes, as well as provide insight into basic aspects of human blur perception.

Accommodation, Ocular↗

The relationship between age and colour content in fundus images.

INTRODUCTION: The morphological appearance of the ocular fundus is one of the key parameters used in the diagnosis and management of retinal disease. However, optical imperfections in the refractive media result in blurring, low luminance and contrast, and changes in the colour composition of the image which can be seen as an increasing yellowish appearance with age. The introduction of a method for quantifying this age-related change in colour content may help in diagnosing and grading pathological changes in the eye lens which are secondary to ocular and systemic diseases. METHODS: A total of 102 digitized fundus images from 102 healthy subjects (mean age = 50.4 years, range 7.0-94.3 years) were used to build a model for estimating the age of the subject from the colour content of the images. RESULTS: Estimation of age from the fundus images could be done within approximately 16 years. This variation could be reduced considerably by analysis of repeated photographs from the same examination. CONCLUSION: The colour content of fundus images can be used to estimate the ages of healthy subjects. Furthermore, when the colour content of fundus images deviates from that expected according to subject age, this may indicate causes other than age of increased light absorption in the lens, such as cumulative exposure to hyperglycaemia in diabetic patients. This could potentially be used to identify patients with undiagnosed type 2 diabetes in the general population and help to establish their risk of developing late diabetic complications as the cumulative exposure to hyperglycaemia is unknown at the time of diagnosis of the disease.

Adolescent↗

Visually impaired children with posterior ocular malformations: pre- and neonatal data and visual functions.

AIM: To analyse pre- and neonatal data and ocular findings in children with visual impairment caused by posterior ocular malformations. METHODS: Medical records were scrutinized, dried blood spot cards were analysed for virus DNA and ophthalmological assessments were performed in 28 children with optic nerve hypoplasia (ONH) and 10 with optic/chorio-retinal coloboma. RESULTS: Prenatal exposure to possible teratogens was documented in 5/28, herpes simplex virus type 1 DNA was identified in the dried blood spot cards of 1/26 children and neonatal hypoglycaemia in 12/28 children with ONH. The time delay from ocular to endocrinological diagnosis and treatment was 3 years. Children with ONH and severe visual impairment had endocrinopathy more often (11/13) than ONH children with better visual functions (5/15). Prenatal exposure to teratogens or neonatal hypoglycaemia was not identified in any of the children with coloboma. CONCLUSION: Neonatal hypoglycaemia was common in children with ONH. Severe visual impairment predicted endocrinopathy. Analysis of dried blood spot cards could serve as an additional diagnostic tool in children with ocular malformations.

Child↗

Recent developments in detection methods for microfabricated analytical devices.

Sensitive detection in microfluidic analytical devices is a challenge because of the extremely small detection volumes available. Considerable efforts have been made lately to further address this aspect and to investigate techniques other than fluorescence. Among the newly introduced techniques are the optical methods of chemiluminescence, refraction and thermooptics, as well as the electrochemical methods of amperometry, conductimetry and potentiometry. Developments are also in progress to create miniaturized plasma-emission spectrometers and sensitive detectors for gas-chromatographic separations.

Journal Article↗

[Disorders of function in pitting of the optic disk].

Using 44 eyes with optic disk pits as reference material, these pits are described with particular attention to the functional disturbances which accompany them. Visual acuity is reduced in about 50% of eyes thus affected. In two-thirds of the cases the deterioration in visual acuity occurs suddenly and without warning, prompting the patient to see an ophthalmologist. The cause of the sudden disturbance of vision is the formation of subretinal fluid, which presumably originates in the vitreous and then passes through the pit into the subretinal space. In the present study it was demonstrated that pits in the optic disk are also accompanied by a defect in the nerve fiber layer. Under meticulous examination these scotomas can be identified both in static perimetry by their steep scotoma rims and ophthalmoscopically by the absence of the nerve fiber layer and of subretinal fluid. The nerve fiber defects often cause only small scotomas which go unnoticed by the patient. In some cases, when they affect the center, they can also result in reduced visual acuity and strabismus.

Adolescent↗

A clinical evaluation of the american optical SR III subjective refractor.

The American Optical SR III Subjective Refraction System is a recent addition to the vision care field. Subjective refractions were performed, using the SR III, on 275 eyes of 139 subjects (clinic patients, optometry students, staff members, and faculty members) and the results were compared to clinical refractive data. Although subjective refraction results were found to compare favorably to the clinical results, the instrument was found to be limited to the extent that there is no provision for binocular vision testing and no provision for near vision testing.

Humans↗

Characteristics of the optic disc cup.

The frequency distribution of the optic cup/optic disc ratio (CDR) and the optic cup depth (OCD) were investigated using clinical data. The mean CDR is 0.30 (SD = 0.13), and the mean OCD is 2.10 D (SD = 0.89 D). Seventy-four percent of 1352 eyes had a CDR of 0.3 or less, and 68% of 1168 eyes had an OCD of 2 D or less. The distribution of the CDR's differs from a normal distribution, but that of the OCD's is nearly normal.

Adolescent↗

Sequential tilt and tilted power of thin lenses.

PURPOSE: The purposes of this article were, for any sequence of tilts applied to a thin lens, to calculate an equivalent turn and single tilt, to show how to use the equivalent turn and tilt to calculate the tilted power of the lens, and, given the desired tilted power, to calculate the power of the untilted lens necessary to compensate for the effects of tilt. The untilted lens may be stigmatic (spherical) or astigmatic (spherocylindrical). METHODS: The analysis makes use of rotation matrices to represent rotation in space and previous work in third-order optics on oblique central refraction. RESULTS: Equations are presented for calculating the combination of turn and tilt that is equivalent to any sequence of tilts. They are specialized for the particular case of combinations of faceform and pantoscopic tilts and allow the decomposition of an arbitrary tilt into a combination of turn and pantoscopic and faceform tilts. The equations also lead to a procedure for calculating or compensating for the tilted power of a sequentially tilted thin lens. CONCLUSIONS: Previous work on the effect of tilt on thin lenses has been generalized to handle combinations of arbitrary tilts.

Equipment Design↗

Modal interference and dynamical instability in a solid-state slice laser with asymmetric end-pumping.

We observed complicated emission patterns consisting of different transverse modes and associated intensity pulsations at beat frequencies between pairs of transverse eigenmodes in a solid-state thin-slice Fabry-Perot laser with asymmetric end-pumping. The dependence of transverse patterns and pulsation frequencies on pump power has been demonstrated. The interference among nonorthogonal transverse eigenmodes, which are formed in a deformed Fabry-Perot microcavity possessing an asymmetric, gradient refractive-index potential for optical waves, is proposed for explaining observed instabilities. Intensity modulations have been remarkably reproduced by numerical simulations of model equations.

Journal Article↗