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At least 505 records · Page 28Linked to original sources
PubMed1975

Angiography in the management of aneurysms of the abdominal aorta. Its value and safety.

The course of 190 patients with aneurysm of the abdominal aorta who underwent preoperative aortography was reviewed to determine the safety and usefulness of that procedure. There were no serious complications; minor problems occurred in only four patients and did not affect operative therapy. In 21 patients, the clinical impression of aneurysm was found to be incorrect. Surgically important findings included suprarenal extension of the aneurysm in nine patients, and demonstration of stenotic lesions in the renal arteries (37 patients) or superior mesenteric artery/celiac axis (17 patients). Helpful findings were associated aneurysms (26 patients), multiple renal arteries (28 patients), and occlusive lesions in the lower extremities or aortocranial system in 82 and eight patients respectively. Such information was found useful in planning operative procedures and minimizing operative time and blood loss. In our experience, angiography in patients with aneurysm of the abdominal aorta is both safe and informative.

Aged↗
PubMed2001

[Collateral compensation of blood flow and hemodynamics of the lower extremities in atherosclerotic occlusion of abdominal aorta].

Results of investigation of collateral blood flow in 159 patients with atherosclerotic occlusion of abdominal aorta of various kinds were presented. There was shown, that a. mesenterica superior constitutes the main visceral branch, securing the blood circulation compensation in total, high and middle occlusion of abdominal aorta and in low occlusion--a. mesenterica inferior. The change of direction and enhancement of blood flow along a. epigastric inferior was noted in all the patients. In spite of identity of total volumetric blood flow along the collateral branches, the volumetric blood flow velocity along the lower extremities arteries is determined by the level and spread of aortal occlusion.

Angiography↗
PubMed1990

[Aneurysm of the abdominal aorta. Is arterial hypertension a risk factor?].

OBJECTIVE: the purpose of this study was to measure ecographically and ascertain the characteristics of the abdominal aorta in a sample of the male population over sixty years, and try to correlate the findings with some so-called "risk factors" most currently quoted in the medical press, such as arterial hypertension, diabetes mellitus, tobacco consumption and coronary or cerebrovascular diseases. MATERIAL AND METHODS: this is a preliminary note of the results obtained in the first forty patients in a prospective study (still ongoing). They were choose randomly from all those admitted to the general medicine ward of Medicine I Hosp. St. Maria or attended at the Medicine or Cardiology/Hypertension outpatient clinics at the same hospital. Pearson's linear correlation, Student's t test for not paired samples and chi-square tests were used to analyze the results. MEASUREMENTS AND MAIN RESULTS: the medium value obtained for the abdominal aorta diameter (daa) was 28.8 mm (SD. +/- 3.6). In this sample there was no correlation between the age and daa (r:0.03), nor any statistical difference (chi-square) in the daa between the subgroups creating regarding the existence of hypertension no hypertension, active smoking/no smoking habits, or the association of all these so-called risk factors added to diabetes as opposed to their absence (the number of patients is still insufficient to reach statistical significance). CONCLUSIONS: in this study no risk factor/marker of the aneurysm of the abdominal aorta was so far detected in a population of aged male patients, but in some groups (as in the association of multiple factors) the number of patients was insufficient to reach any significant statistical conclusion.

Aged↗
PubMed2005

[Treatment of rupture of the infrarenal aneurysm of the abdominal aorta].

One of the 15 most common cause of death in USA is rupture of the aneurism of the abdominal aorta. In 8-10% cases patients have no previous symptoms of aneurysm of the abdominal aorta, and they are coming to thr hospital with clinical picture of rupture This paperwork presents one such case. After assuming the data of basic lab. findings, clinical finding, and diagnostic procedures, an urgent operation was indicated. A resection of aneurismaticly changed infrarenal portion of abdominal aorta and its reconstruction with synthetic graft was done. In postoperative course we noticed cardiac decompensation followed by acute ischaemic attac of the left lower limb. It was solved by urgent disobliterative procedure--embolectomy in local anestesion. Patient was discharged after 21 day in good general condition.

Aged↗
PubMed2006

[New technologies in diagnosis and surgical treatment of the abdominal aorta aneurysm].

Modern views about occurrence, pathogenesis, and methods of diagnosis and surgical treatment of abdominal aorta aneurysm are adduced. Application of new highly informative diagnostic methods, an adequate anesthesiological support, differentiated methods of surgical intervention have permitted to reach marked progress in the treatment of patients with abdominal aorta aneurysm.

Aorta, Abdominal↗
PubMed1987

[Pulsed Doppler echocardiographic detection of regurgitant blood flow in the ascending, descending and abdominal aorta of patients with aortic regurgitation].

To ascertain whether the presence of retrograde holo-diastolic flow (RHF) in the ascending, descending or abdominal aorta is indicative of the severity of aortic regurgitation (AR), ascending, descending and abdominal aortic flow velocities were measured by pulsed Doppler echocardiography in 35 patients with AR and in 18 patients without AR, confirmed by aortography. Among the 35 patients with AR, 15 had mitral regurgitation, 11 had mitral stenosis, eight had aortic stenosis, five had prosthetic mitral valves, four had prosthetic aortic valves and two had aorto-pulmonary shunts. Satisfactory flow velocity recordings were obtained from the ascending aorta of 47 patients (89%), from the descending aorta of 39 patients (74%) and from the abdominal aorta of 43 patients (81%). In the ascending aorta, 30 of 32 AR patients with satisfactory recordings had RHF, while only one of the 15 patients without AR had RHF. None of the patients without AR had RHF, in either the descending or abdominal aorta. In the descending aorta, all 11 patients with 3+ or 4+ AR independently determined by aortography had RHF, while only three of 16 patients with 1+ or 2+ AR had RHF. Two of the three patients had aorto-pulmonary shunts. In the abdominal aorta, all 11 patients with 3+ or 4+ AR had RHF, while only one of the 22 patients with 1+ or 2+ AR had RHF. The latter patient had an aorto-pulmonary shunt. Identification of RHF in the descending or abdominal aorta is a useful means of distinguishing patients with severe AR from those with minimal or no AR.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed2006

Roles of insulin-like growth factor II in cardiomyoblast apoptosis and in hypertensive rat heart with abdominal aorta ligation.

Although IGF-II activating the IGF-II receptor signaling pathway has been found to stimulate cardiomyocyte hypertrophy, the role of IGF-II in cardiac cell apoptosis remains unclear. This study aimed to identify the roles of IGF-II and/or IGF-II receptors (IGF-II/IIR) in cardiomyoblast apoptosis and in hypertensive rat hearts with abdominal aorta ligation. Cultured rat heart-derived H9c2 cardiomyoblasts and excised hearts from Sprague-Dawley rats with 0- to 20-day complete abdominal aorta ligation, a model of ANG II elevation and hypertension, were used. IGF-II/IIR expression, caspase activity, DNA fragmentation, and apoptotic cells were measured by RT-PCR, Western blot, agarose gel electrophoresis, and TUNEL assay following various combinations of ANG II, IGF-II/IIR antibody, CsA (calcineurin inhibitor), SP-600125 (JNK inhibitor), SB-203580 (p38 inhibitor), U-0126 (MEK inhibitor), or Staurosporine (PKC inhibitor) in H9c2 cells. ANG II-induced DNA fragmentation and TUNEL-positive cells were blocked by IGF-II/IIR antibodies and antisense IGF-II, but not by IGF-II sense. IGF-II-induced apoptosis was blocked by IGF-IIR antibody and CsA. The increased gene expressions of IGF-II and -IIR induced by ANG II were reversed by U-0126 and Sp600125, respectively. Caspase 8 activities induced by ANG II were attenuated by U-0126, SP-600125, and CsA. DNA fragmentation induced by ANG II was totally blocked by SP-600125, and CsA and was attenuated by U-0126. In rats with 0- to 20-day complete abdominal aorta ligation, the increases in IGF-II/IIR levels in the left ventricle were accompanied by hypertension as well as increases in caspase 9 activities and TUNEL-positive cardiac myocytes. ANG II-induced apoptosis was reversed by IGF-II/IIR blockade and coexisted with increased transactivation of IGF-II and -IIR, which are mediated by ERK and JNK pathways, respectively, both of which further contributed to cardiomyoblast apoptosis via calcineurin signaling. The increased cardiac IGF-II, IGF-IIR, caspase 9, and cellular apoptosis were also found in hypertensive rats with abdominal aorta ligation.

Angiotensins↗
PubMed2006

Life-threatening hemorrhage from abdominal aorta following a percutaneous renal biopsy.

We report on a case of life-threatening abdominal aorta hemorrhage following percutaneous renal biopsy. A 42-year-old woman with chronic kidney disease stage 2 and microscopic hematuria underwent a percutaneous renal biopsy to evaluate renal insufficiency. One hour following the biopsy procedure, she complained of an abdominal pain and developed signs ofoligemic shock. In despite of 4 blood units transfusion, the patient continued to be in shock. She was transmitted urgently to the operating room without any other examinations (such as abdominal computer tomography) and underwent an emergency laparotomy. A transverse tear in the abdominal aorta was identified as the bleeding site, and after occlusion, the hemorrhage was stopped. The patient gradually recovered and she was discharged in good clinical condition after a few days.

Adult↗
PubMed2000

Telomere attrition of the human abdominal aorta: relationships with age and atherosclerosis.

Little is known about the turnover rate (i.e. the rate of replication and death) of cells in the intima and media of human arteries as a function of age and atherosclerosis. One indicator of the replicative history of cells is telomere length. In this work we explored the rate of telomere attrition as a function of age and atherosclerosis in cells of the human abdominal aorta. Telomere length, measured by the terminal restriction fragment using Southern analysis, was determined in the intima and media of the distal (infrarenal) versus proximal (suprarenal) segments of the abdominal aorta. Telomere length was then correlated with age and atherosclerotic grade. The rate of age-dependent telomere attrition was higher in both the intima and media of the distal versus proximal abdominal aorta. In addition, telomere length was negatively correlated with atherosclerotic grade. However, after adjustment for age, this relationship was not statistically significant. The high rate of age-dependent telomere attrition in the distal abdominal aorta probably reflects enhanced cellular turnover rate due to local factors such as an increase in shear wall stress in this vascular segment.

Adolescent↗
PubMed1983

Metabolic and morphologic changes induced by serotonin in skeletal muscle of rats after abdominal aorta ligation.

Myopatic changes observed in muscle of rats after abdominal aorta ligation and/or serotonin injection have been regarded as a suitable model to explore the possibility that vasoactive treatments induce muscular damage similar to human myopathies. In the present study, we investigated the effect of serotonin administration to normal and aorta-ligated rats on cAMP-dependent protein-kinase (PK) and hydrolytic enzymes in skeletal muscle.

Animals↗
PubMed1994

Endarterectomy versus angioplasty in the treatment of localized stenosis of the abdominal aorta.

OBJECTIVE: To compare the outcome after aortoiliac endarterectomy and percutaneous transluminal angioplasty (PTA) of the aorta for localized stenosis of the lower abdominal aorta. DESIGN: Chart review of patients treated over a 5-year period. SETTING: A university centre. PATIENTS: Sixteen women, all of whom were smokers; 5 had hyperlipidemia, 4 had evidence of coronary artery disease, 3 were hypertensive, and 1 was diabetic. INTERVENTIONS: Aortoiliac endarterectomy (eight women) and PTA (eight women). MAIN OUTCOME MEASURES: Ankle-brachial pressure index (ABI), degree of claudication and clinical outcome. RESULTS: Angiography showed localized stenosis of the lower aorta in all patients, aortic hypoplasia in nine patients and associated common iliac disease in seven. None of the eight patients managed by aortoiliac endarterectomy had complications or died. All were free of claudication at a mean follow-up of 29 months and had durable improvement in their ABI: mean ABI preoperatively was 0.69 (standard deviation [SD] 0.1) and postoperatively was 1.06 (SD 0.07). Of the eight patients treated by PTA, only one had partial dilatation; another had a subintimal tear with worsening symptoms and a fall in ABI, requiring surgery within 18 months. The remaining six were symptom free after a mean follow-up of 13.4 months. Aortic PTA resulted in improvement of the ABI: mean ABI before PTA was 0.69 (SD 0.19) and after PTA was 1.06 (SD 0.15). CONCLUSIONS: Endarterectomy is a safe and effective method of treating occlusive disease limited to the distal aorta. PTA appears to be less reliable. However, it is recommended as the initial treatment of choice in patients with angiographically suitable lesions because it is less invasive.

Adult↗
PubMed1983

[Coarctation of the abdominal aorta: diagnosis, pathogenesis, medical or surgical treatment. 7 cases].

Seven cases of coarctation of the abdominal aorta are reported. The diagnosis, suggested by the presence of arterial hypertension associated with nonperception of the arterial pulse in the lower limbs and/or systolic murmur in the abdomen, is supported by non-invasive investigations, such as Döppler flowmetry of lower limb arteries and ultrasonography of the abdominal aorta. Arteriography, however, is mandatory because of frequently associated lesions of other arteries, notably renal and/or intestinal arteries. The type and location of these lesions are of prime importance to therapeutic decision. According to the results of the present study, surgery may not be required in all cases and may be replaced, in some very specific circumstances, by medical treatment. There is still disagreement concerning the congenital or acquired origin of this type of aortic coarctation and the mechanism of hypertension. The various theories put forward are discussed.

Adolescent↗