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New hope for identifying the unidentified. The National Crime Information Center unidentified person/missing person files.

The National Crime Information Center Unidentified Person/Missing Person Files offer computer comparison of descriptive data on unidentified dead and living persons with data entered on missing persons. Completion of a simple, but detailed standard form allows entry of descriptors of physical characteristics, fingerprint classification, dentition, anthropologic and x-ray findings, optic prescriptions, medical devices, surgical procedures, serology, jewelry, and clothes. Medical and law enforcement agencies collect the descriptive data on the unidentified; families and law enforcement agencies collect missing persons information. Entry for both is via law enforcement regional or state NCIC computer terminals. Continuous comparison and cross search of both files is initiated upon entry of either form.

Autopsy↗

Comparison of digital dental X-ray systems with self-developing film and manual processing for endodontic file length determination.

Human skulls were sectioned into 15 sextants. Teeth were then removed and 45 canals were instrumented to their apical foramina. Endodontic files were glued in place at random distances from the apical foramina. Image geometry was maintained by a custom mounting jig. Images were captured with self-developing film, manually processed D-speed film, and a digital radiographic system (Dexis). Digital images were read on a conventional color monitor (cathode ray tube) and a laptop screen (active-matrix liquid crystal display). Fifteen dentists measured the distance from the file tip to the apical foramen of the tooth. Results showed that the measurement error was significantly less for the digital images than for the film-based images. It is likely that these statistical differences may not be of great clinical significance because the digital images could be measured in increments < 0.25 mm.

Analysis of Variance↗

Torque during canal instrumentation using rotary nickel-titanium files.

Nickel-titanium engine-driven rotary instruments are used increasingly in endodontic practice. One frequently mentioned problem is fracture of an instrument in the root canal. Very few studies have been conducted on torsional characteristics of these instruments, and none has been done under dynamic conditions. The purposes of this study were to measure the torque generated and the apical force applied during instrumentation with a commercial engine-driven nickel-titanium file system, and to relate torque generated during simulated clinical use to torsional failure of the instruments. Ten extracted human teeth (five with small-sized and five with medium-sized straight root canals) were instrumented with Quantec Series 2000 files, and the torque and apical force generated were measured. The applied apical force was generally low, not exceeding 150 g in either small or medium canals. The torque depended on the tip size and taper of each instrument, and on canal size. Instruments with 0.05 and 0.06 taper generated the highest torque, which was greater in small than in medium canals. The torque at failure was significantly (p < 0.001) higher than torque during instrumentation, but with considerable variation in the extent of the difference.

Analysis of Variance↗

A method to assess rotary nickel-titanium files.

A number of studies have assessed the physical properties and durability of rotary nickel-titanium files. This study proposes a method that will permit this to be done in a controlled manner. Files of 0.04 taper; 25 mm in length; and in ISO sizes 25, 30, and 35 were each used four times in plastic blocks. The canal in the block had a working length of 17 mm; 30 degrees curvature; 15 mm radius of curvature; size 20 at the apex; and the curve began at 8 mm from the orifice of the canal. The irrigant used was Glyde. An electric handpiece was configured to rotate at 200 rpm and secured to the testing device, which also held the plastic block. The testing device controlled the depth of penetration at 17 mm; the load was at 8 N and the rate of penetration was at 120 mm/min. Controls were not subjected to use. Torsional moment (N-cm) and angular deflection (degrees) at failure were determined on a Torsiometer/Memocouple. Data (n = 5) were analyzed by analysis of variance. Tukey-Kramer intervals at the 0.05 significance level were determined. Torsional moment significantly increased with an increase in size. Torsional moment also significantly increased for used instruments, compared with controls. Angular deflection had a range of 480 degrees to 810 degrees for the instruments tested.

Analysis of Variance↗

A comparison of shaping ability using ProFile, GT file, and Flex-R endodontic instruments in simulated canals.

A total of 160 resin-simulated canal blocks with 20-degree or 30-degree curvature were prepared by ProFile rotary instruments, GT rotary files, and the balanced force technique with Flex-R files. Using an image analysis computer application, the pre- and postoperative images were stored and superimposed, and then the amount of material removed from the preoperative inner and outer curved walls was measured at five levels in the apical 5 mm of the canal. The time required for canal preparation, including irrigation, and the time taken to change instruments was recorded. At 1 mm from the apical end, the directions of canal transportation were most frequently toward the outer aspect of the curvature, with the only exception being the canals shaped by the balanced force technique in which more was removed from the inner aspect. The balanced force technique required more preparation time than the rotary instrumentation.

Analysis of Variance↗

Cleaning efficiency of nickel-titanium GT and .04 rotary files when used in a torque-controlled rotary handpiece.

This study determined if the cleaning efficiency of nickel-titanium rotary files in an endodontic electric handpiece using a no-torque control setting was superior to that obtained when using the torque-control feature. Fifty extracted human anterior teeth with straight canals were divided into two groups of 20 and two control groups of 5. Canals were instrumented with GT and .04 ProFile nickel-titanium files until a size 35 advanced to working length. Samples were sectioned and the apical 6 mm of the canal was photographed (x20) and projected onto a 3- x 4-foot grid with squares measuring 0.5 inches each. Total debris was the percentage of the number of squares containing debris versus the total number of squares. The teeth in the torque-controlled group showed an average of 24.99% debris versus 15.55% for the teeth in the no-torque group. The difference was not statistically significant; therefore, no difference can be said to exist between the two torque settings in terms of cleaning efficiency.

Dental Alloys↗

In vitro comparison of shaping abilities of ProTaper and GT rotary files.

This study analyzed the abilities of ProTaper and GT Rotary files to shape the curved canals of extracted mandibular molars. Twenty mesial canals with curvatures ranging from 23 to 54 degrees (Weine analysis) were radiographically selected from a group of 58 molars. The specimens, divided into two groups, were instrumented using the two systems according to the manufacturer's guidelines. Using a radiographic platform and a contrast medium, reproducible preinstrumentation and postinstrumentation radiographs were taken. A computer analysis allowed magnification and superimposition of the images to measure the preparation asymmetry and the linear amount of dentin removal at five points along the canals and to detect canal aberrations. Instrument failures, working time, and working length changes were recorded. The dentin removal and the mean asymmetry showed no significant differences between the two systems. Neither aberrations nor significant changes in working length resulted, but two instruments separated in each group. Working time was shorter for ProTaper files (p < 0.05).

Dental Instruments↗

Evaluation of apical debris removal using various sizes and tapers of ProFile GT files.

The purpose of this study was to evaluate the effect of preparation taper using size #20 or size #40 ProFile GT files on the ability to introduce irrigant and remove debris from root canals. Forty-eight bilaterally matched pairs of extracted teeth were instrumented using.04-,.06-,.08-, and.10-tapered files with one tooth of each pair enlarged to size #20 and the other to size #40. The teeth were sectioned at 1 mm and 3 mm from the apex, and the amount of remaining debris was calculated as a percentage of the total lumen area. The following variables were evaluated: apical preparation size, preparation taper, total volume of irrigation, depth of irrigation needle penetration, and number of instrument changes needed to reach working length. Compared with the size #40 preparations, a significantly greater percentage of remaining debris was observed in the size #20 preparations at the 1-mm level for all tapers except the.10 taper group in which there was no significant difference (p = 0.982). There were no significant differences between any groups at 3 mm. Results suggest that debris is more effectively removed using.04,.06, and.08 ProFile GT instruments when the apical preparation size is larger (size #40) compared with size #20 apical preparations. When a taper of.10 can be produced at the apical extent of the canal, there is no difference in debris removal between the two preparations sizes.

Analysis of Variance↗

Patient followup after radical prostatectomy by Internet medical file.

PURPOSE: The development of the Internet and the need for regular followup of patients often living a long way from the hospital led us to develop a followup dossier for those with localized prostate cancer treated with laparoscopic radical prostatectomy. MATERIALS AND METHODS: This feasibility study was based on 140 patients who agreed to test this system. The website was opened on a server specifically devoted to this project with all required computer security. The website is composed of pages comprising the hospital discharge summary, and operative and histology reports. A quality of life questionnaire based on the assessment of urinary continence and sex life, and a prostate specific antigen (PSA) assay form are also included. RESULTS: The patient is able to enter his PSA data and complete the questionnaire at home. Results are then sent to the treating physician. A contact page allows the patient and physician to exchange information by text. Of these 100 patients 92 connected regularly to the site with a mean connection rate of 8 per patient (range 1 to 22). Of the patients 98% were satisfied with the various sections of the site, 95% were satisfied with the medical file, 11% noticed connection problems and 14% reported technical problems essentially attributable to incorrect PSA data entry or incorrect functioning of videos due to the absence of appropriate software. CONCLUSIONS: This type of Internet medical service for patients who have undergone surgery requiring regular followup appears to be a useful approach for the future by allowing the maintenance of close contact between the patient and physicians, while avoiding problems related to hospital visits regardless of the patient place of residence. It also provides general practitioners with access to the patient file with patient permission.

Feasibility Studies↗

Validity of cancer registry medicaid status against enrollment files: implications for population-based studies of cancer outcomes.

BACKGROUND: Poor access to or inadequate health insurance contributes to disparities in cancer incidence and mortality. Cancer registry "payer source" data is collected by many cancer registries in the United States and has been used to compare cancer outcomes across insurance types. OBJECTIVES: We evaluated the validity of cancer registry data on patient Medicaid status against enrollment data from Medi-Cal, California's Medicaid program. METHODS: Data from the statewide California Cancer Registry for persons under age 65 years diagnosed with 1) any cancer in 1998 and 1999 or 2) with invasive cervical cancer between 1996 and 1999 were obtained and linked probabilistically to Medi-Cal enrollment files. We compared registry Medicaid status, determined from payer source information, against linkage results and used crosstabulations to calculate sensitivity, specificity, and positive predictive value. These measures were compared across different hospital and patient characteristics and cancer types. RESULTS: Cancer registry Medicaid status data had poor sensitivity (48%), good specificity (98%), and moderate positive predictive value (77%). Measures of validity did not vary substantially by cancer type, stage, patient age, sex, vital status, race/ethnicity, socioeconomic status, or diagnosing hospital size. Registry data undercounted the number of Medicaid patients by 52% and incorrectly assigned Medicaid as a payer to approximately 2% of patients. CONCLUSIONS: As a result of the poor validity of cancer registry Medicaid status data, caution should be used when interpreting cancer outcomes by insurance type calculated from registry payer source data. Linkage of registry data to Medicaid enrollment files represents a more accurate means of identifying Medicaid insurance status.

Adolescent↗

Steady-state properties of single-file systems with conversion.

We have used Monte Carlo methods and analytical techniques to investigate the influence of the characteristic parameters, such as pipe length, diffusion, adsorption, desorption, and reaction rate constants on the steady-state properties of single-file systems with a reaction. We looked at cases when all the sites are reactive and when only some of them are reactive. Comparisons between mean-field predictions and Monte Carlo simulations for the occupancy profiles and reactivity are made. Substantial differences between mean-field and the simulations are found when rates of diffusion are high. Mean-field results only include single-file behavior by changing the diffusion rate constant, but it effectively allows passing of particles. Reactivity converges to a limit value if more reactive sites are added: sites in the middle of the system have little or no effect on the kinetics. Occupancy profiles show approximately exponential behavior from the ends to the middle of the system.

Journal Article↗

Molecular traffic control in single-file networks with fast catalysts.

As a model for molecular traffic control we investigate the diffusion of hard core particles in crossed single-file systems. We consider a square lattice of single-files being connected to external reservoirs. The (vertical) alpha channels, carrying only A particles, are connected to reservoirs with constant density rho(A). B particles move along the (horizontal) beta channels, which are connected to reservoirs of density rho(B). We allow the irreversible transition A-->B at intersections. We are interested in the stationary density profile in the alpha and beta channels, which is the distribution of the occupation probabilities over the lattice. We calculate the stationary currents of the system and show that for sufficiently long channels the currents (as a function of the reservoir densities) show in the limit of large transition rates nonanalytic behavior. The results obtained by direct solution of the master equation are verified by kinetic Monte Carlo simulations.

Journal Article↗

Single-file transport of water molecules through a carbon nanotube.

Recent molecular dynamics simulations of water transport through the interior channel of a carbon nanotube in contact with an aqueous reservoir showed that conduction occurred in bursts with collective water motion. A continuous-time random-walk model is used to describe concerted transport through channels densely filled with molecules in a single-file arrangement, as also found in zeolites, as well as ion channels and aquaporins in biological membranes. Theoretical predictions for different collective properties of the single-file transport agree with the simulation results.

Biological Transport↗

Subdiffusion and long-time anticorrelations in a stochastic single file.

The subdiffusion of a stochastic single file is interpreted as a jumping process. Contrary to the current continuous time random walk models, its statistics is characterized by finite averages of the jumping times and square displacements. Subdiffusion is then related to a persistent anticorrelation of the jump sequences. In continuous time representation, this corresponds to negative power-law velocity autocorrelations, attributable to the restricted geometry of the file diffusion.

Journal Article↗

New Powder Diffraction File (PDF-4) in relational database format: advantages and data-mining capabilities.

The International Centre for Diffraction Data (ICDD) is responding to the changing needs in powder diffraction and materials analysis by developing the Powder Diffraction File (PDF) in a very flexible relational database (RDB) format. The PDF now contains 136,895 powder diffraction patterns. In this paper, an attempt is made to give an overview of the PDF-4, search/match methods and the advantages of having the PDF-4 in RDB format. Some case studies have been carried out to search for crystallization trends, properties, frequencies of space groups and prototype structures. These studies give a good understanding of the basic structural aspects of classes of compounds present in the database. The present paper also reports data-mining techniques and demonstrates the power of a relational database over the traditional (flat-file) database structures.

Journal Article↗

The Powder Diffraction File: present and future.

The International Centre for Diffraction Data (ICDD) produces the Powder Diffraction File (PDF). This paper discusses some of the seminal events in the history of producing this primary reference for powder diffraction. Recent key events that center on collaborative initiatives have led to an enormous jump in entry population for the PDF. Collective efforts to editorialize the PDF are ongoing and provide enormous added value to the file. Recently, the ICDD has created a new series of the PDF, designated PDF-4. These relational database structures are being used to house the PDF of the future. The design and benefits of the PDF-4 are described.

Journal Article↗

Use of a computer data file for storage of heat resistance data on bacterial spores.

The use of a computer data file to compile published heat resistance data on bacterial spores is described. Information relating to sporulation, heating and recovery of the spores, in addition to decimal reduction times at different temperatures has been stored. The data file was constructed using Minitab and an indexer program on a VAX 11/750 computer operating on VMS. Storage of the data in this way enables rapid manipulation and analysis of large quantities of information relating to heat resistance of bacterial spores.

Clostridium↗

The Protein Data Bank. A computer-based archival file for macromolecular structures.

The Protein Data Bank is a computer-based archival file for macromolecular structures. The Bank stores in a uniform format atomic co-ordinates and partial bond connectivities, as derived from crystallographic studies. Text included in each data entry gives pertinent information for the structure at hand (e.g. species from which the molecule has been obtained, resolution of diffraction data, literature citations and specifications of secondary structure). In addition to atomic co-ordinates and connectivities, the Protein Data Bank stores structure factors and phases, although these latter data are not placed in any uniform format. Input of data to the Bank and general maintenance functions are carried out at Brookhaven National Laboratory. All data stored in the Bank are available on magnetic tape for public distribution, from Brookhaven (to laboratories in the Americas), Tokyo (Japan), and Cambridge (Europe and worldwide). A master file is maintained at Brookhaven and duplicate copies are stored in Cambridge and Tokyo. In the future, it is hoped to expand the scope of the Protein Data Bank to make available co-ordinates for standard structural types (e.g. alpha-helix, RNA double-stranded helix) and representative computer programs of utility in the study and interpretation of macromolecular structures.

Computers↗