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PubMed1970

Iatrogenic renal disease.

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Drug-Related Side Effects and Adverse Reactions↗
PubMed1991

[Role of iatrogenic spondylodiscitis among pyogenic spondylodiscitis. 136 cases observed between 1980 and 1989].

The authors report 136 cases of spondylodiscitis due to ordinary organisms seen between 1980 and 1989 and note the increasing incidence of iatrogenic forms which during the past three years accounted for 50 per cent of cases. 60 per cent of these cases of iatrogenic spondylodiscitis complicated a medical of surgical procedure involving the spine (form by direct inoculation). In 40 per cent of cases, the organism came from a site of infection located at a distance (from by blood-borne spread). The clinical picture in cases of primary spondylodiscitis and of iatrogenic disease by blood-borne spread is essentially similar. That of iatrogenic forms by direct inoculation is different: most often young subjects, virtually exclusive involvement of the lumbar spine, fever and inflammatory syndrome less common. Escherichia coli and Staphylococcus aureus were the organisms most often responsible for primary spondylodiscitis (23 and 21.7 per cent of case respectively). Streptococci were in third position only (15.6 per cent of cases). Staphylococcus aureus remained predominant in iatrogenic spondylodiscitis (34 per cent of cases), while Escherichia coli and streptococci were significantly rarer than in primary forms and there was the appearance of Pseudomonas aeruginosa and Staphylococcus albus. No organism was found in 23 per cent of cases of primary spondylodiscitis. This figure reached 44% of iatrogenic forms by direct inoculation. Because of their increasing incidence, these cases of apparently aseptic spondylodiscitis, frequently complicating a procedure involving the spine, are modifying the picture of infectious spondylodiscitis. No doubt worthy of separate identification, they raise the problem of the significance of the concept of aseptic spondylodiscitis.

Adolescent↗
PubMed1984

Staphylococcus aureus bacteraemia: 400 episodes in St Thomas's Hospital.

Four hundred episodes of Staphylococcus aureus bacteraemia occurred in St Thomas's Hospital from 1969 to 1983, accounting for 17.5% of all episodes of bacteraemia. The mortality was 24%, half attributable to underlying disease, and was highest in patients over 50. Almost 60% of the bacteraemias were acquired in hospital, and the source of the organism was generally obvious, with vascular access sites the most common (37%). Bone and joint infections accounted for 11.5% of episodes and endocarditis for 7%. Most staphylococci were resistant to penicillin only; three isolates were resistant to methicillin and five to fusidic acid. Microbiologists seldom influenced directly the choice of initial antibiotic treatment (though this usually conformed to the hospital's antibiotic prescribing policy) but had considerable influence over definitive treatment, usually cloxacillin or flucloxacillin alone or in combination with fusidic acid. S aureus bacteraemia is easy to identify and treat, though underlying disease may influence the outcome. Efforts should be made to prevent the largely iatrogenic disease.

Adolescent↗
PubMedDate not supplied

[Misleading pains in the lower limbs of rheumatologic origin].

Pain in the lower limbs related to rheumatic disease may be the source of diagnostic difficulties when it presents in the guise of pseudo-vascular manifestations. A narrow spinal canal and atypical neuralgia may present a very misleading clinical picture. Similarly, traumatic muscular pathology and bone trauma and tumours may also be misleading. A popliteal cyst and reflex sympathetic dystrophy may simulate venous disorders. Iatrogenic disease, particularly complications of anticoagulant treatment also need to be recognized.

Anticoagulants↗
PubMed1990

[Iatrogenic pathology, its role in the structure of patient morbidity and thanatogenesis].

Iatrogenic diseases which were an immediate cause of death or played an important role in thanatogenesis were found in 319 (14.2%) of 2250 autopsy cases of patients with surgical, therapeutical and neurosurgical pathology. Surgical iatrogenesis was established in 226 (70.8%), and therapeutical one in 59 (18.5%) cases. Revealing a neurosurgical iatrogenesis (10.7%) represented considerable difficulties. The pathologists, in the authors opinion, do not pay a sufficient attention to establishing iatrogenic pathology in spite of its constant increase during last years and the fact it occupies a considerable percentage in the morbidity structure and thanatogenesis. The necessity to respect the instructions of the ICD-9th concerning "second diseases" is outlined. The pathologists together with clinicians should try to clarify the causes of iatrogenic diseases and their true incidence.

Adult↗
PubMed1988

[Iatrogenic pathology in pediatrics].

Literature and original data have been analyzed concerned with iatrogenic diseases in fetuses and children at various time periods, as well as the sequelae due to iatrogenic childhood disturbances.

Female↗
PubMed1997

[Hemospermia].

Haemospermia is a relatively frequent symptom in urology, especially in young subjects. It is often benign, but is important because of the anxiety it can cause to the patient. The predominant aetiology of haemospermia is prostatic and seminal vesicle disease. Iatrogenic aetiologies, generally without severity, are due to the development of instrumental diagnosis and treatment in urology. Recent progress in the field of medical imaging, particularly transrectal ultrasonography and magnetic resonance imaging, has greatly contributed to the diagnostic and therapeutic approach to haemospermia.

Blood↗