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[The mechanisms of allergic damage to the bronchoalveolar apparatus in poultry plant workers].

Specific and non-specific mechanisms of defense and damage were studied in 296 poultry breeders, 20 of them were diagnosed the exogenic allergic alveolitis (EAA), the so-called "breeder's lung". The following characters were found: an increase in the blood leucocyte phagocytic activity, non-specific neutrophilic damage values, specific neutrophilic damage and specific lymphocyte damage values, lactate dehydrogenase activity, circulated immune complexes level, immunoglobulins A and M in blood serum in breeders with EAA. Only breeders with service of 1-5 and 11-15 years have shown no changes in non-specific neutrophilic damage values. A decrease in the T-lymphocyte content, theophylline-sensitive and theophylline-stable lymphocyte subpopulations in blood serum of breeders with EAA were observed as well.

Antibody Formation↗

[The effectiveness of immunological methods in the diagnosis of leptospirosis].

The effectiveness of Leptospira antigenic erythrocyte diagnosticum increases 4- to 8-fold due to the preliminary activation of erythrocytes and Boivin's antigen with 0.001-0.002 M solution of potassium periodate. ELISA with the use of conjugate based on antiglobulin serum and catalase is twice as sensitive as ELISA with conjugate on the basis of penicillinase, 3 times as sensitive as ELISA with conjugate on the basis of Leptospira hyperimmune serum and catalase and 10-20 times as sensitive as the passive hemagglutination test and the microagglutination and lysis test.

Animals↗

Cellularity of adipose tissue in meat animals.

Present information indicates that for meat animals adipocyte number is achieved most rapidly in the perirenal depot and least rapidly in the interfascicular of intramuscular depot. Adipocyte volume appears to be largest in the perirenal depot and smallest in the interfascicular and intermuscular depots. The best estimates available suggest that adipocyte hyperplasia is completed by 14 months of age in bovine animals and 5 months of age in porcine animals. However, because of certain technique limitations and the presence of many small adipocytes in very obese animals, these estimates must be considered very tentative. Studies in ovine and porcine animals indicate that early under-nutrition is not effective in reducing the number of subcutaneous and perirenal adipocytes later in life. However, the number of interfascicular adipocytes may be reduced. Several studies have demonstrated that the interfascicular adipocytes are very late developing and that adipocyte number is very important to the total quantity of intramuscular lipid.

Adipose Tissue↗

[The cellular level of integration in the body of the workers at a poultry plant with extrinsic allergic alveolitis].

Studied at the cell level of integration were the following indices for nonspecific reactivity: phagocytic activity of leucocytes (PhAL), a parameter characterizing damage to neutrophils (PDN), nitroblue tetrasolium test (NBT-test), the activity of alkaline phosphatase (AlPhA) of neutrophils, and the activity of acid phosphatase (AcPhA) of lymphocytes in EAA (exogenous allergic alveolitis) workers with reference to the service duration. PDN was shown to be raised in EAA workmen who had worked at the integrated poultry farm for 6-10 and 16-20 years. The parameter characterizing damage to neutrophils did not differ from control values in the workmen with 1-5 and 11-15 yr service duration. It was found that the activity of AlPh of neutrophils was decreased in EAA workers with 1-5 and 11-15 yr service duration. The activity of AlPh did not change with 6-10- and 16-20 yr service duration. The results from NBT-test, determinations of PhAL, and the activity of AcPh of lymphocytes showed their elevation in EAA workmen with the service duration 1-20 years. In summary, study at the cell level of integration into the indices of nonspecific reactivity in workmen with 1-2-yr length of service showed a decrease in the activity of AlPh neutrophils and an increase in the activity of AcPh of lymphocytes, PhAL, PDN, NBT-test, suggesting some disturbance in metabolism in leucocytes and involvement of nonspecific mechanisms of protection of organism in EAA.

Adult↗

[The characteristics of the immune response of the body in poultry plant workers with extrinsic allergic alveolitis].

There have been studied parameters characterizing cellular and humoral immunity such as T-lymphocytes, subpopulations of theophylline-sensitive (Ths-E-RFL), theophylline-resistant (Thr-E-RFL) lymphocytes, blood serum content of immunoglobulins A, M in the integrated poultry farm workers with exogenous allergic alveolitis (EAA) with regard to their work record. The results obtained pointed to the reduction of the blood serum content of T-lymphocytes, Ths-E-RFL and Thr-E-RFL in the integrated poultry farm workers with service duration ranging from 1 to 20 years, this evidencing inhibition of cellular immunity in EAA. The level of serum immunoglobulins A, M was found to be elevated in workers with a work record of 1-20 years in EAA. In summery, study into the immunologic parameters such as T-lymphocytes, Ths-E-RFL, immunoglobulins A, M levels in the blood serum of the workers with service duration 1-20 years showed reduction in T-lymphocytes, Ths-E-RFL, Thr-E-RFL and rise in immunoglobulins A, M, suggesting inhibition of the cellular link of immunity and stimulation of humoral immunity.

Adult↗

Warts in butchers.

Explore the source record for details and available documents.

Disease Susceptibility↗

[The epidemiological characteristics of single cases of campylobacteriosis in urban inhabitants].

The results of the analysis of the epidemic situation in Campylobacter infection and the epidemiological markers of the strains of the infective agent have demonstrated that Campylobacter infection, registered as single cases among the residents of Vologda, has an epidemic character. An intensive and uncontrolled process among fowl (chickens) and the absence of effective measures of specific prophylaxis make it necessary that a system of hygienic measures be given priority in the complex of measures aimed at the prophylaxis of Campylobacter infection.

Acute Disease↗

Brucellosis: the situation in Western Nigeria.

Over 55% of 7161 people examined in different parts of Western Nigeria have positive Brucella abortus-antibodies in their sera. Higher incidence of titres were found among dairy farmers and slaughtermen than in the general population. The rates of infection among the human and the cattle populations in two farms studied were very similar. There was evidence of high rate of cross-infections going on in one of these farms: more than 63% of the herd in this farm showed serological evidence of active brucellosis. The socio-economic implications of high incidence of bovine brucellosis in a rapidly developing country, like Nigeria, are outlined. The need for the establishment of public health laboratories to facilitate early diagnosis of active disease and the necessity for full collaboration between the medical and veterinary professions for the proper control (and eradication) of brucellosis in Nigeria are discussed.

Agricultural Workers' Diseases↗

[Supervision in veterinary health (author's transl)].

The supervision programme of the Veterinary Chief Inspectorate of Public Health comprises nearly fifty projects, a number of which are discussed. This will give the authorities an opportunity to gain a more complete view of the state of the human food package, for which inspection of the individual animal in the slaughter-house does not so far offer any practical possibilities. Attention is drawn to the important place occupied by the veterinary nutritionist in the protection of human health.

Animal Nutritional Physiological Phenomena↗

[Significance of starter cultures for raw sausage aging in view of food and nutrition hygiene].

The authors studied the effects of liquid starter cultures on the survival of pathogenic germs. It was found that the foreign bacteria tested differed in growth limitation which is obviously dependent on acidity and the amount of lactic acid produced by fermentation. Since the pathogenic bacteria differ in the ability to survive, it is imperative to observe strict hygienic measures in preparing starter cultures and to use absolutely sterile monocultures for raw sausage ageing.

Escherichia coli↗