Ionic bases of slow, depolarizing responses of cardiac ganglion neurons in the crab, Portunus sanguinolentus.
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Animals↗
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Results for “PROCAINE AND COMPOUNDS”
Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.
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Electrophysiology of the heart of an isopod crustacean: Porcellio dilatatus. II. Effects of ions and membrane permeability inhibitors.
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Action Potentials↗
A new parasympathomimetic agent: 1-methyl-5-chloroindoline methylbromide.
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Abdominal Muscles↗
Comparative local anesthetic potencies of lidocaine and metabutoxycaine.
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Anesthesia, Local↗
Studies of ear drops used for treatment of acute otitis media.
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Acute Disease↗
Effect of diet composition on chick growth response to different types and levels of feed medication.
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Animal Feed↗
Corticosteroids administered intradurally for relief of sciatica.
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Adrenal Cortex Hormones↗
Effect of procaine and tetraethylammonium on 42-K efflux from smooth muscle of sheep carotid arteries.
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Animals↗
[Combined effect of phenothiazine derivatives and novocaine].
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Antipsychotic Agents↗
Sympocaine: a new local anesthetic.
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Anesthesia, Local↗
[Electrophysiological investigations of the mechanism of chemoreception. II. Modification of afferent impulsed in intestinal nerves during action of carbon dioxide and novocaine and during metabolic disorders induced with monoiodoacetic acid].
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Acetates↗
[Soluble penicillin & relatively insoluble derivatives: sodium penicillin G, procaine penicillin G & benzathine penicillin G; pharmacological & therapeutic considerations].
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Penicillin G↗
[Clinical and experimental researches with a combination of sodium-, procaine- & benzathine penicillin G].
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Penicillin G Benzathine↗
[Prolonged anesthesia in tonsillectomy].
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Analgesia↗
Use of primacaine in intraocular ophthalmic surgery; a clinical evaluation.
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Eye↗
[Minor symptoms in family medicine; keratitis caused by ultraviolet rays].
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Anesthetics, Local↗
[Local surface anesthetic activity of some higher organic acid salts of procaine].
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Anesthesia, Local↗
Further studies on the pharmacodynamic properties and organ selectivity of octylonium bromide.
At concentrations ranging from 8.5 to 30 microM, octylonium bromide (OB) did not affect sodium channel availability measured as maximal rate of depolarization (Vmax) of cardiac action potential. On the other hand, at equieffective spasmolytic concentrations (1.1 mM), procaine markedly inhibited Vmax as well as other electrophysiological parameters. These experiments indicate that at fully effective spasmolytic concentrations OB is devoid of local anaesthetic properties. In concentrations up to 10 microM OB did not affect phosphodiesterase activity in crude homogenates of rat colon which were inhibited by both papaverine (EC50 = 0.7 mM) and theophylline (EC50 = 3.5 mM). OB was more effective in antagonizing spasmogen-induced contractions on colonic as compared to tracheal preparations. Inhibition of Neurohormone-induced calcium ion mobilization from cellular and extracellular pools remains the mechanism of action which best explains the spasmolytic effects of OB on intestinal smooth muscle.
Action Potentials↗