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AO incompatibility in a small group of developmentally disabled children.

Prevalence of fetal-maternal AO incompatibility was studied in a group of 150 children having developmental delay in the neuropsychological sphere. In a given population the number of A children having O mothers (AO incompatibility) should equal the number of O children having A mothers (OA compatibility). However, in the study group we observed 26 children in the former and 14 children in the latter category. This difference was statistically significant (p = 0.04). The frequency of AO incompatibility in the developmentally disabled population was higher (17.3%) than that in 437 child-mother pairs of the general population (10.1%). It was not possible to demonstrate association of any specific neurological defect with AO incompatibility, although the children born from AO incompatible pregnancies tended to start walking later than the other children of the study group.

ABO Blood-Group System↗