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Migraine development, treatments, research advances, and anesthesia implications.

The purpose of this course is to update anesthesia providers on the phenomenology and biological mechanisms underlying migraines. As experts in pain management who encounter this common ailment, anesthesia providers frequently are consulted to assist in patient care. Effective assessment and treatment of migraine will lead to better anesthesia management. Knowledge of preventive measures of surgical patients with migraine history can avoid events that can elicit a headache attack. The clinical implications of migraine disorder--and each patient's preventive medication profile--is relevant to safe, accommodative anesthesia nursing care. Research advances in migraine treatment may profoundly improve our current pain relief measures. Adequate knowledge of the development, treatments, and research advances concerning migraine will improve patient care.

Acute Disease↗

[Prenatal diagnosis of neuroblastoma].

One of the prognostic factors for neuroblastoma is age at the time of diagnosis: neuroblastoma detected prenatally or in the first year of live have a more favorable outcome. Antenatal diagnosis is essential early management. Knowledge of local tumor extent is invaluable in determining the appropriate treatment, and MR imaging has proved to be the most useful procedure in this regard.

Female↗

Utilization of the medical librarian in a state Medicaid program to provide information services geared to health policy and health disparities.

OBJECTIVE: The role of two solo medical librarians in supporting Medicaid programs by functioning as information specialists at regional and state levels is examined. SETTING: A solo librarian for the Massachusetts Medicaid (MassHealth) program and a solo librarian for the New England States Consortium Systems Organization (NESCSO) functioned as information specialists in context to support Medicaid policy development and clinical, administrative, and program staff for state Medicaid programs. BRIEF DESCRIPTION: The librarian for MassHealth initially focused on acquiring library materials and providing research support on culturally competent health care and outreach, as part of the United States Department of Health and Human Services Culturally and Linguistically Appropriate Services in Health Care Standards. The NESCSO librarian focused on state Medicaid system issues surrounding the implementation of the Health Insurance Portability and Accountability Act. The research focus expanded for both the librarians, shaping their roles to more directly support clinical and administrative policy development. Of note, the availability and dissemination of information to policy leaders facilitated efforts to reduce health disparities. In Massachusetts, this led to a state legislative special commission to eliminate health disparities, which released a report in November 2005. On a regional level, the NESCSO librarian provided opportunities for states in New England to share ideas and Medicaid program information. The Centers for Medicaid and Medicare are working with NESCSO to explore the potential for using the NESCSO model for collaboration for other regions of the United States. RESULTS/OUTCOMES: With the increased attention on evidence-based health care and reduction of health disparities, medical librarians are called on to support a variety of health care information needs. Nationally, state Medicaid programs are being called on to provide coverage and make complex medical decisions regarding the delivery of benefits. Increasing numbers of beneficiaries and shrinking Medicaid budgets demand effective and proactive decision making to provide quality care and to accomplish the missions of state Medicaid programs. In this environment, the opportunities for information professionals to provide value and knowledge management are increasing.

Health Policy↗

Carving a niche: establishing bioinformatics collaborations.

OBJECTIVES: The paper describes collaborations and partnerships developed between library bioinformatics programs and other bioinformatics-related units at four academic institutions. METHODS: A call for information on bioinformatics partnerships was made via email to librarians who have participated in the National Center for Biotechnology Information's Advanced Workshop for Bioinformatics Information Specialists. Librarians from Harvard University, the University of Florida, the University of Minnesota, and Vanderbilt University responded and expressed willingness to contribute information on their institutions, programs, services, and collaborating partners. Similarities and differences in programs and collaborations were identified. RESULTS: The four librarians have developed partnerships with other units on their campuses that can be categorized into the following areas: knowledge management, instruction, and electronic resource support. All primarily support freely accessible electronic resources, while other campus units deal with fee-based ones. These demarcations are apparent in resource provision as well as in subsequent support and instruction. CONCLUSIONS AND RECOMMENDATIONS: Through environmental scanning and networking with colleagues, librarians who provide bioinformatics support can develop fruitful collaborations. Visibility is key to building collaborations, as is broad-based thinking in terms of potential partners.

Computational Biology↗

Evidence-based dentistry: a clinician's perspective.

Evidence-based dentistry is a discipline that provides best, explicit-based evidence to dentists and their patients in shared decision-making. Currently, dentists are being trained and directed to adopt the role of translational researchers in developing evidence-based dental practices. Practically, evidence-based dentistry is not usable in its current mode for the provision of labor-intensive services that characterize current dental practice. The purpose of this article is to introduce a model of evidence-based dental practice. This model conceptualizes a team approach in explaining problems and solutions to change current dental practice. These changes constitute an evidence-based dental practice that involves the electronic chart, centralized database, knowledge management software, and personnel in optimizing effective oral health care to dental patients.

Databases as Topic↗

Making clinical decisions using a clinical practice guideline.

Clinical practice guidelines are statements developed from best evidence about clinically relevant appropriate care. A simulated patient case is presented to demonstrate how to use a CPG in decision-making in determining a clinical decision. Conceptualized knowledge management software templates are provided to explain a process by which best evidence is retrieved from a primary, centralized network database. Templates describe the process of converting a clinical question into a research question, retrieving best evidence, and performing data analysis for the outcome of individualizing and optimizing a clinical decision. Templates also describe the reciprocation of information to update CPGs by translational researchers who manage and build the primary, centralized network database.

Aged, 80 and over↗

Collaborating for a cause--Creating partnerships between IT and academia.

An international nursing shortage is driving the redesign of nursing education curriculum. Providing nursing students with an opportunity for hands on use of advanced healthcare technology is critical to the development of highly competent nurses who are prepared not only to fully interact in the healthcare domain, but to also participate in its re-engineering via IT. The academic institution with an integrated IT solution in clinical simulation labs can become a place where students can learn the skills, understand the potential, participate in the selection and evaluation of software systems and eventually help to craft IT solutions that benefit both the patient and the practice of nursing and medicine. As the healthcare environment continues to change - pushing curricular redesign, the expectation that educators will increase the integration of IT into coursework and clinical experiences is increasing. The challenge however, is not only to educate the students, but to also educate faculty who often possess limited amounts of IT knowledge. Faculties, like students, have limited time and learning outcomes are enhanced when hands-on and practical educational opportunities are available. This presentation therefore will not only focus on the student; instead, the gestalt of integrated teaching/learning from faculty and student perspectives will be addressed. The challenges, including identifying partnership opportunities, identifying financial resources to support such partnerships, gaining institutional support, determining criteria to evaluate student performance, and strategies for engendering faculty support will be discussed, along with solutions on how they can be overcome. The presentation will also highlight the benefits of the partnership for both the institution and the industry vendor. The institution can benefit from the access to the vendor's software, hardware, and expertise. By using advanced clinical solutions in the classroom and hospital setting, students and faculty can benefit from access to evidence based content and knowledge management. Opportunities for faculty and student research also become possible. In turn, the vendor has access to the institution's intellectual capital, participation in research studies co-authorship in academic publications, and enhancements of product design. The outcome is a nursing informatics educational partnership empowering nurses to utilize and drive the enhancements of advanced technology to improve the delivery of patient care.

Cooperative Behavior↗

Sequelae of stomach surgery.

Gastric surgery has undergone continuous evolution since the 19th century. At present it is a highly sophisticated technique which provides symptomatic relief for the vast majority of patients operated upon for peptic ulcer disease. Although the overall incidence of complications has decreased, a variety of complications continues to occur and radiological examination plays a critical role in their detection, evaluation, and management. Knowledge of the variations in surgical terminology and commonly used eponyms provides the basic framework for discussion. Familiarity with the radiological appearance of the normal postoperative stomach together with an understanding of its physiology are essential prerequisites to the recognition of possible complications. Operative techniques may result in a radiographic appearance which simulates disease. Conditions as diverse as bezoars, afferent and efferent loop problems, marginal ulceration, anastomotic leakage, prolapse, and intussuception may all be characterized by distinct and highly specific radiographic changes. Physiologic problems such as dumping and malabsorption may also reflect their presence by X-ray changes. The radiographic features in a large number of surgical complications are discussed and illustrated. The importance of the radiographic examination in the postsurgical stomach is emphasized.

Digestive System↗

The cooperative study of sickle cell disease: review of study design and objectives.

Although sickle cell disease has been known for years and many of its manifestations have been recognized, the "natural history" or clinical course of the disease from early childhood to death is not well understood. This is largely because of the variable degree of severity, the variability of the many manifestations, and the complexity of the interaction of the disease process with other health-related events. Therefore, information obtained to date hs been largely anecdotal, retrospective in nature, and lacking statistical stature. Consequently, there are many unanswered clinical questions about this illness. Therefore, the National Heart, Lung, and Blood Institute of the National Institutes of Health has initiated a large-scale, multi-institution investigation based on an analytical and specific process, which is described. This 5-year study will provide the data base to answer existing questions and provide information to improve present medical management. Knowledge of risk factors, rates of progression, and incidence and nature of complications will directly impact on the care of sickle cell patients. In addition, this information will improve counseling related to family decisions and opportunities now available for prenatal diagnosis. Likewise, a data bank of clinical manifestations and a classification or index of severity are essential as emerging antisickling agents require clinical trials.

Anemia, Sickle Cell↗

A systems model for food purchasing.

The approach taken in this paper of isolating seasonal characteristics of products and then using that information to determine when those products should be ordered to minimize the system's purchasing costs appears to be valid. A drawback to using this approach, however, is acquiring appropriate data. The authors used data which they believed to be appropriate for thier market purchasing environment but which are not necessarily valid for other locations and/or environments. The prospective user of this model must find and obtain data suitable for the environment and isolate those products which appear seasonal. Only a small percentage of the items used possess any seasonal properties. There is also the obvious problem of using past data to determine future outcomes. Past price patterns do not necessarily continue into the future, although they should be at least indications, barring unusual farm and/or market situations. As with all decision modeling approaches, however, this model should be followed with caution. While the approach is valid, the procedure is no substitute for knowledgeable management of food service functions. Results from the model should provide additional input to guide food purchasing decisions but should not be used unequivocably. When property used, however, this procedure will allow food buyers to come closer to the goal of optimally purchasing food products from a systems point of view then is currently possible.

Alabama↗

Rubeosis iridis in retinoblastoma and pseudoglioma.

The high incidence of rubeosis iridis accompanying retinoblastoma has been reaffired. Factor common to ocular tumors in general and retinoblastoma, as well as reactions to retioblastoma that have some contributory effect upon vascularization of the iris have been studied and complied. No single causative factor emerged, although tumor necrosis obviously played an important role. To a lesser extent, the site, location, and intraocular extension bore some relationship to neovascularization. That iris neovascularization carries a more grave prognosis, until now only a clinical impression, was definitely confirmed. Clinicians, therefore, studying patients with retinoblastoma would be well advised to pay more attention to the iris and anterior segment since recognition of changes leads to more timely and knowledgeable management. It was hoped that increased recognition of rubeosis would differentiate between eyes with retinoblastoma and those with pseudoglioma; however, an equally high incidence of neovascularization accompanied certain pseudogliomas. In both studies, as is often the case, numerous interesting observations were made; several with clinical implications. Finally, a frequently associated glaucoma, suggested by the anterior segment histologic features, went urecognized and unrecorded in these patients.

Diagnosis, Differential↗

Health science graduates: preparation for the workplace.

The research reported in this article was undertaken to assess the perceptions of health science graduates in the fields of health information management, occupational therapy, orthoptics, physiotherapy, and speech pathology regarding their perceptions of the adequacy of undergraduate preparation in meeting the demands of a changing health care environment. An instrument was devised for use by graduates on the basis of the skills and workplace behaviours specified by experienced practitioners in the above fields as necessary in newly recruited graduates. A total of 527 health science graduates completed the 52 item instrument. The statistical analyses indicated that 11 factors define the adequacy of graduates' preparation for the workplace. Health science graduates perceived themselves to have been more thoroughly prepared on certain workplace dimensions than on others. Specifically, graduates perceived themselves to be ill-equipped on dimensions concerned with workplace management, knowledge of the health industry, and coping in the workplace. Graduates also perceived themselves to be inadequately prepared in terms of communicating with clients, health professionals, and the general public. The strengths of their courses were perceived to be in completing essential tasks, having confidence in the clinical role, in ethical practice, in pursuit and application of knowledge, and having a realistic expectation of the workplace role. The results are discussed in terms of the need to address curriculum changes.

Adult↗

DHNet: a model for international research collaboration.

Internet technology has changed the way information is accessed, shared, and stored. This technology has supported the growth of scientific networks based on the need for improved communications and a team approach to problem solving. Scientists throughout the world are now able to come together in "virtual laboratories" or "collaboratories" to conduct research, analyze data, and discuss findings in a more timely and cost-efficient manner. The DHNet is based on a collaboratory model. It is a Web-based Internet resource designed to encourage research collaboration among dental hygiene professionals without regard to geographic location. The DHNet creates an electronic infrastructure that facilitates the linking, relating, and clustering of concepts that are critical to advancing a body of knowledge. It also creates a new standard for placing information on the Internet, which currently lacks conventions and structures for knowledge management. Designed to be maintained by its users with minimal staff support, the DHNet provides a mechanism for electronic publication of clinical observations, research, research in progress, and other document/media types. DHChat, the discussion forum component, provides an electronic communications tool for discussing topics of interest, research questions, and ways in which researchers would like to work together. Depending on the nature of the investigation, multi-site studies can be conducted or researchers can be responsible for different aspects of the same study. Video conferencing from desktop computers now permits synchronous discussion, enabling participants to see each other and work on the same document. The purposes of this article are to discuss the design of the DHNet as a model for supporting international research collaboration, and to discuss issues related to the use of electronic technology.

Computer Communication Networks↗

Data and decisions: can mental health management be knowledge-based?

Three major factors suggest a healthy future for data-based decision making within mental health authorities: (1) the improved knowledge base related to the treatment and management of serious mental illness, (2) advances in data-processing technology and (3) conceptual advances in management information system design, most notably the National Institute of Mental Health (NIMH) Mental Health Statistics Improvement Package. This paper briefly outlines these three factors and goes on to examine information needed by state mental health authorities (SMHAs) to enhance decision making. The client-level data necessary for data-based policy decisions, while still scarce, are increasingly available and are increasingly finding homes within SMHA management information systems. As SMHAs improve their information systems to accommodate such data, they face substantial implementation challenges and substantial payoffs in terms of increased knowledge for decision making.

Decision Support Systems, Management↗

Knowledge of risk management strategies, and information and risk management preferences of women at increased risk for ovarian cancer.

Little research is available on the level of knowledge about ovarian cancer risk management options in women at increased risk for this disease. The study objectives were to evaluate this together with the information and ovarian cancer risk management preferences of high-risk women. One hundred and twenty-nine women were assessed after their attendance at one of six familial cancer clinics in relation to knowledge of surveillance and/or preventative strategies for reduction of ovarian cancer risk, preferences for particular strategies, and information preferences. Screening was selected by 57 (44%) women as the preferred risk management option. One hundred and five women (82%) indicated a wish for as much information as possible about ovarian cancer, including both good and bad outcomes and 114 (89%) reported a preference for sharing treatment decisions with their health professional. Participants' knowledge about ovarian cancer risk management options was significantly associated with educational levels (Z = -3.2, p=0.001) and whether or not ovarian cancer was included in the family history (Z = -2.3, p = 0.018). Findings from this present study indicate that women at increased risk of ovarian cancer who attend familial cancer clinics want as much information as possible about this disease and they want to be involved in the decision-making process. Women who reported a lower level of education (no post-school qualifications) may be most likely to benefit from additional educational strategies designed to supplement genetic counseling to improve their knowledge levels.

Adult↗

Current knowledge in the management of children and adolescents with sickle cell disease: Part 1, Physiological issues.

This article reviews the current state of the knowledge in the management of children and adolescents with sickle cell disease (SCD). A thorough review of the literature concerning physiological issues including the clinical manifestations of SCD as well as current treatment modalities is included. Therapeutic management of health and illness for a child with SCD is discussed in relation to primary, secondary, and tertiary prevention. Recommendations for nursing practice and research are made.

Adolescent↗

Relationships of asthma knowledge, self-management, and social support in African American adolescents with asthma.

Despite nationwide efforts to manage asthma, the adverse outcomes of asthma continue to increase, especially in African American adolescents. The purpose of this study was to examine the relationships among asthma knowledge, self-management, and social support in African American adolescents with asthma. A correlational descriptive study was conducted using a convenience sample of 53 identified asthmatic adolescents from the Southern metropolitan school system in Alabama. Asthma knowledge was measured by the Parcel Knowledge about Asthma Questionnaire, social support by the Norbeck Social Support Questionnaire, and asthma self-management behaviors by the Asthma Behavioral Assessment Questionnaire. Both asthma knowledge and social support had significant positive relationships (r=0.31, r=0.30, respectively) with asthma self-management behaviors and accounted for 14% of self-management behaviors variability. Further studies are needed to understand how to better manage asthma in adolescents.

Adolescent↗

Domestic violence: examining nurses' and doctors' management, attitudes and knowledge in an accident and emergency setting.

Despite the increasing awareness of the important role that Accident and Emergency (A&E) personnel have in the diagnosis and management of domestic violence victims, there is limited knowledge about the nurses' or doctors' knowledge of or attitudes to domestic violence in Australian health care settings. In addition nursing and medical staff still receive very little training in working with domestic violence victims. This study was conducted to examine the existing knowledge, attitudes to and management strategies for domestic violence victims among 111 nurses and doctors in two rural and two country hospitals. The findings indicate that A&E staff recognise the importance of their role in the identification and management of domestic violence victims. Despite this they do not have all the skills necessary to deal effectively with the problem or to be able to access local resources for assistance. Education programs should focus on direct questioning techniques, and recognition of risk factors and protocols to provide guidelines for police involvement.

Adolescent↗