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A pilot project to assess the association of anticholinergic symptoms with anticholinergic serum levels in the elderly.

STUDY OBJECTIVE: To evaluate whether serum anticholinergic drug activity would be a useful clinical tool in helping to predict anticholinergic toxicity. DESIGN: A prospective study that included a retrospective chart review. SETTING: Two nursing home facilities. SUBJECTS: Thirty-one elderly volunteers between ages 69 and 98 years. INTERVENTION: Each subject completed a two-part interview. First, anticholinergic symptoms were evaluated and then cognitive function was assessed by three neuropsychiatric tests. Blood (10 ml) was collected to measure anticholinergic activity. MEASUREMENTS AND MAIN RESULTS: Eight subjects had detectable serum anticholinergic activity and scored higher on the Symbol Digit Modalities test than those with no detectable activity. No statistical difference was seen between the groups with respect to symptoms or results of the Mini-Mental and Auditory-Verbal Learning tests. CONCLUSION: The clinical usefulness of serum anticholinergic activity as a predictor for anticholinergic toxicity was not established under the experimental design of this study.

Aged↗

Control of intestinal parasitic infection--a pilot project in Lao PDR.

Intestinal helminths are a very common but still rather unrecognized public health problem. An attempt was undertaken to control the three important parasites, ie Ascaris, Trichuris and hookworm. Two villages in Vientiane Province in Lao PDR were selected, one as an intervention and the other as control village. Intervention measures started by providing mass treatment against Ascaris, Trichuris, hookworm and other intestinal parasitic infections in both villages. Health education and other intervention measures were implemented in the intervention village, which significantly influenced the re-infection rates in this village. These achievements were not due to an improvement of the availability of toilets or personal hygiene alone but more to the villagers' improved understanding of the route of the parasitic infections. It was concluded that intervention methods should be directed more towards particular age groups. Particular attention should be paid to control parasitic infections among females.

Adolescent↗

[Quality assurance in basic psychosomatic care. Report of an expert survey within the scope of the Federal Public Health Administration instigated pilot project].

This article outlines a nationwide quality improvement project in counselling funded by the German Ministry of Health. To develop the project, expert surveys and consensus conferences are currently organized by the coordination center. A questionnaire with mainly open questions was sent to 32 teachers in general practice. Counselling for psychiatric, psychosomatic and psychosocial problems in primary care was regarded as an important field for quality assurance. The experts believed short psychotherapy to be an integral part of family medicine as some 30% of our patients present with complaints caused by psychosocial or psychological reasons. However, only some 70% of patients receive a specific treatment. The experts rated better recognition of psychosomatic problems as the most important area for quality improvement. Suitable interventions to improve the physicians' ability in the area mentioned were continuing medical education, balint groups, quality circles and flexible guidelines. The experts made invaluable contributions to the development of a practice documentation for psychosocial problems.

Adult↗

[Ultrasound detection of rib fractures for verifying fracture diagnosis. A pilot project].

Since the diagnosis of rib fractures caused by blunt thoracic trauma is often missed on X-ray, attempt have been made to detect unknown fractures with ultrasound. Ultrasound was initially researched, as a diagnostic technique in a preliminary study of 10 patients with known rib fractures. Subsequently, in the main study, 21 patients with clinically suspected rib fractures but normal thoracic X-rays were examined with ultrasound, and rib fractures were detected in 16 patients. The diagnosis of rib fractures by ultrasound was substantiated by an increase of activity in the technetium scintigram in 11 of 11 patients. We found further increases of activity in the scintigram in two more ribs in 7 of these 11 patients. This finding is explained by the presence of nondislocated rib fractures that are veiled to ultrasound when a disconnection of the rib's contour is missed during respiration. The diagnostic procedure is explained with reference to case studies. In summary, findings recorded in this study showed that ultrasound investigation is a more reliable method of diagnosis than X-rays examination.

Accidents, Traffic↗

Effectiveness of a pilot project of discharge planning in Taiwan.

The purpose of this study was to examine the effects of a nurse-designed discharge-planning project in a teaching hospital in Taiwan. A before-and-after quasi-experimental design was used. Craniotomy (n = 112) and stroke (n = 171) patients were recruited and divided into control and intervention groups. Outcome indicators included length of hospital stay, change in activities of daily living (ADL), rate of nursing home placement, rate of unplanned readmission, and level of satisfaction. In the stroke sample length of hospital stay was shorter in the intervention group than in the control group. In the craniotomy sample unplanned readmission was less frequent in the intervention group than in the control group. No differences were found between the control and intervention groups in other outcome indicators.

Activities of Daily Living↗

Early detection of skin cancer by family physicians: a pilot project.

BACKGROUND: Malignant melanoma is rising quickly in incidence and mortality rates. Family physicians (FPs) have been reported to lack confidence in diagnosing skin cancers. OBJECTIVE: The aim of this study was to determine whether an educational intervention can improve FPs' abilities to diagnose skin cancers. METHODS: The design was a prospective, randomized trial which included a skin cancer questionnaire, a video intervention, and a skin biopsy review. RESULTS: Pre-intervention, FPs answered 57% of the questions correctly on the skin cancer questionnaire. Post-intervention, the video intervention group scored higher than did the control group. The video intervention group removed 10% fewer benign lesions and almost 3 times more malignant lesions compared with their pre-intervention biopsy rate. No findings were statistically significant. CONCLUSION: An educational intervention may improve FPs' knowledge and diagnosis of skin cancer. Our results may guide future studies with larger sample sizes in developing a skin cancer continuing medical education (CME) course for FPs.

Adult↗

Groups for parents of children with Down's Syndrome and multiple handicaps: a pilot project.

One of the main purposes of an Infant Stimulation Program is to assist parents in finding ways of adjusting to and developing the potential of the handicapped child. The Peel Infant Stimulation program at the Mississauga Hospital in Mississauga, Ontario, while aptly fulfilling this purpose, noted that in some instances the stress of having a handicapped child added tension to the marital relationship. In addition, some parents appeared to have difficulty recovering from the news of their child's condition. In response to these observations a consultant with expertise in groups, couples, and family therapy was hired to help form groups for parents who appeared to be having difficulties. An Occupational Therapist from the Infant Stimulation Program was trained in group leadership while co-leading the groups with the consultant. The article explores the rationale for the groups, describes the sessions, and discusses a number of issues that are pertinent to the running of the groups. The intent of the article is to encourage staff working in similar programs to investigate the use of parent groups.

Down Syndrome↗

Healthy Hearts at work: Prince Edward Island Heart Health Program CSC worksite pilot project.

Prince Edward Island experiences a higher-than-average death rate from cardiovascular disease. The Prince Edward Island Heart Health Program is a health promotion/disease prevention research project of Health Canada and the Prince Edward Island Department of Health and Social Services. This paper describes and evaluates a worksite program, based on the principles of community mobilization, that was initiated with the Civil Service Commission of the Prince Edward Island government. The building of a partnership, the risk appraisal session administered in the workplace, the establishment of an Employee Wellness Committee, and subsequent programming which has occurred in the workplace were the key components in the process. Collaboration with the partner agency and participation of employees in the planning process has resulted in the delivery of programs which could not have been achieved by one of the agencies alone, without many additional resources. It is hoped that these characteristics of collaboration and employee participation will also result in sustainability of this initiative when PEI Heart Health is no longer involved.

Cardiovascular Diseases↗

Evaluation of follow-up services for elderly people prescribed hearing aids: report of a pilot project.

The first stage of a programme to determine the effectiveness of different types of follow-up service for elderly people prescribed hearing aids is described. Follow-up sessions of two hours each were held at fortnightly intervals and were given to groups comprising six patients. Three treatments were compared, one consisting of two follow-up sessions, the second of four sessions, and the third none (the control group). Two groups received each treatment. The results failed to demonstrate any advantage from the treatments. The men, who were more handicapped by their hearing loss, did better than women and there was a predominance of men in the control groups. The necessity of some follow-up service was demonstrated since a substantial proportion of patients were not utilising their aids satisfactorily at six months after issue and had problems which were then resolved. Any follow-up programme must concentrate very heavily on basic handling and maintenance of the aid, for most of the difficulties experienced were with these.

Aftercare↗

Dosimetric support of the International Programme on the Health Effects of the Chernobyl Accident (IPHECA) pilot project: main results and problems.

The problem of post-Chernobyl dosimetry is unique in its complexity in the history of radiation medicine and radiation protection. This is because the early experience of mass exposure of people (bombing of Hiroshima and Nagasaki, Windscale and South-Ural accidents, exposure of inhabitants of Nevada in the United States of America, the Semipalatinsk area in the former USSR, the Marshall Islands, and the Goiånia accident in Brazil, and others) differed both in the much simpler structure of the irradiation source and in the number and characteristics of exposed persons. It is obvious that post-Chernobyl dosimetry, both as an independent problem, and as a tool for epidemiological studies, requires significant expertise and economic and technical expenditures. Extensive and deep research has been carried out in Ukraine for the past 10 years. This article reviews the main results of these studies.

Adolescent↗

Hospital attitudes: preliminary findings from donor action pilot projects.

PURPOSE: As part of the Donor Action collaboration (Eurotransplant Foundation, The Netherlands; Organización National de Transplantes, Spain; and The Partnership for Organ Donation, USA), a hospital survey was administered to gather baseline data on staff attitudes about organ donation and level of self-reported skills/confidence in performing a range of organ donation roles. METHODS: A standard survey instrument was administered in two hospitals in Spain, two in The Netherlands and one in the UK. In four hospitals the survey was administered to all ICU staff; in one hospital it was administered to a random sample of hospital staff. The instrument was created in English, and translated into Spanish and Dutch for the hospitals in each country. RESULTS: Data were analysed by country and showed consistently strong perceptions that organ donation saves lives (97%). Support for donation (95%) and willingness to donate one's own organs (82%) were high in all three country samples. Significant differences in belief were observed when respondents were asked whether they agreed that organ donation helps families with their grief. The UK respondents were more likely to agree (57%), with lower levels of agreement in Spain (47%) and The Netherlands (14%) (P < 0.0001). Average ratings of skills/confidence were highest for notifying the transplant coordinator (49%) and comforting the family (48%) with lower confidence reported regarding explaining brain death (34%), introducing organ donation (32%), and requesting organ donation (26%). Ratings varied widely across countries with UK respondents expressing the highest level of self-reported confidence, and Spanish respondents the lowest level. For example, 77% of UK respondents reported themselves skilled/confident explaining brain death, versus 47% of Dutch respondents and 11% of Spanish respondents (P < 0.0001). Similar results were seen regarding requesting organ donation: UK 53%; The Netherlands 30%; Spain 13% (P < 0.0001). CONCLUSIONS: There has been a lack of data about hospital staff attitudes and skills to allow for comparison across national systems, and to support the targeting of specific strategies to the needs within different countries. These results show the feasibility of collecting and comparing data across national systems. These pilot findings also suggest that there may be important differences in attitudes and self-perceived skills/confidence across countries. Work remains to correlate attitudes and self-perceived skills to actual performance. It is noteworthy that the sense of staff preparedness was lowest in Spain which has the highest donation rates. This may reflect the degree to which role specialization in donation has been successfully integrated into hospital practice. Expansion of the survey to additional hospitals will help to answer such questions.

Attitude↗

Effects of hyperbaric oxygen therapy on children with spastic diplegic cerebral palsy: a pilot project.

Hyperbaric oxygen (HBO2) therapy for children with cerebral palsy (CP) is not new. Research documenting the effects in this population has been anecdotal. We evaluated the effects of HBO2 therapy for 25 children (X = 5.6 +/- 1.6 yr) with a functional diagnosis of spastic diplegic CP. Pre- and post-HBO2 evaluations consisted of the following measures: gross motor function measure (GMFM), fine motor function (Jebsen test for hand function), spasticity (modified Ashworth scale), video analysis, and parental questionnaire. The protocol for HBO2 therapy was 20 treatments of 95% oxygen at 1.75 atm abs for 60 min. The Wilcoxon matched-pairs signed-rank test for non-parametric measures was used to compare pre- and post-treatment data. Results showed improved gross motor function in three of the five items in the GMFM test, improved fine motor function in three of the six hand tests, reduced spasticity in three of four muscle groups when assessed by a physician specializing in CP, and improvements for four of nine questions posed to parents.

Cerebral Palsy↗

Interprofessional education in palliative care: a pilot project using popular literature.

A need to introduce the concepts of death and dying to the medical and health sciences undergraduate curriculum was identified at the University of Ottawa, Ontario, Canada. As care of the terminally ill is complex and requires the collaborative involvement of a diverse group of health care professionals, an interprofessional educational approach was utilized to address this need. A seminar course was developed using popular literature as the basis for learning, and offered to first and second year medical students, fourth year nursing students and graduate students in spiritual care. The discussion of roles and the provision of care within the context of works of selected literature provided a focus that enabled the students to transcend their disciplinary barriers, and to better understand the perspectives and contributions that other team members bring to patient care. Evaluation findings suggest that meaningful interprofessional education can be introduced effectively to students either prior to or while they are maturing in their professional roles.

Clinical Clerkship↗

Meaning of occupational engagement in life-threatening illness: a qualitative pilot project.

INTRODUCTION: The onset of a personal crisis combined with the resultant disruption in occupational routines may challenge a person's identity as a capable and healthy individual. However, it remains unclear how individuals regain a sense of health and well-being in the period following a personal crisis. RESEARCH OBJECTIVE: To explore occupational engagement and its meaning to individuals following a life-threatening diagnosis. METHOD: Semi-structured interviews were conducted with three women diagnosed with breast cancer. The data were analyzed using a constant-comparative approach to identify common themes. RESULTS: The primary theme that emerged was "Doing = Living." This theme and the underlying themes illustrated the connection between meaningful occupational engagement and one's self-perception as capable and healthy. These findings suggest that occupational engagement may provide the medium through which 'deconstructive' or 'reconstructive' messages concerning the self are relayed between persons and their environment. IMPLICATIONS: In a period of personal crisis, such as a life-threatening diagnosis, individuals may turn to those occupations that are meaningful to regain a sense of control and normalcy in their lives.

Breast Neoplasms↗

[The pilot project "Soteria Bern" in treatment of acute schizophrenic patients. II. Results of a comparative prospective follow-up study over 2 years].

Following on a previous publication [15], outcomes of 22 acute schizophrenic index patients treated mainly with no- or low-medication strategies and with milieu therapeutic, socio-therapeutic and psychotherapeutic methods in the open therapeutic community "Soteria Berne" are compared, in a 2-year prospective study, with pairwise matched controls from 4 different traditional settings. There were no significant differences concerning psychopathology, living situation, work situation, combined evaluation and relapse rate after 2 years. Total dosage of medication was less than half, but total costs about 1/3 higher in the index group. Differences of costs were directly related to the inclusion of the-often prolonged-phase of rehabilitation in the in-patient treatment in "Soteria", and disappear when this phase is shifted to other settings. These results and additional observations concerning subjective aspects speak in favour of the creation of other treatment facilities of the same type.

Activities of Daily Living↗

Depression screening in a university campus pharmacy: a pilot project.

OBJECTIVE: To evaluate the usefulness of a depression screening tool in a university campus pharmacy. DESIGN: Uncontrolled study. SETTING: University campus pharmacy. PARTICIPANTS: 25 individuals were screened while waiting for a prescription to be dispensed or while browsing in the pharmacy. INTERVENTIONS: Completion of a depression screening tool and a follow-up participant satisfaction survey to rate the usefulness of the depression screening tool. MAIN OUTCOME MEASURES: Scores on the depression screening tool and descriptive analysis of participant satisfaction survey. RESULTS: One participant was rated as depressed and one participant as "borderline" depression on the screening tool. Overall, 64% (16/25) of participants rated the screening tool as very useful, 92% (23/25) felt very comfortable while completing the screening tool, 40% (10/25) were very likely to read the provided written information, and 60% (15/25) learned about depression or themselves by participating in the survey. CONCLUSION: Depression screening is feasible in a university campus pharmacy. Participants reported feeling comfortable discussing depression with a pharmacist in a university campus pharmacy. In addition, they considered the information provided by the pharmacist on depression to be useful.

Adolescent↗

[Pilot project for eradicating maedi-visna in Walliser blacknose sheep].

Maedi-Visna is a lentiviral disease of sheep with a worldwide distribution. The transmission of the virus occurs primarily via colostrum and milk from the infected ewe to its newborn lamb but also horizontally between sheep. The most obvious clinical symptoms are progressive dyspnea and emaciation. In this prospective study an eradication based on serological testing and removing of seropositive animals was performed in 24 flocks of sheep of the breed "Walliser Schwarznasenschafe" leading to a reduction of the seroprevalence from 36% to 1% within two years. The control group consisted of 21 flocks of sheep. Lambs of seropositive ewes had a 7.6 times higher risk to seroconvert within their first two years of life compared to those of seronegative ewes. The dynamics of the spread of the infection were studied in birth cohort groups. Cohort animals of seropositive ewes showed an obvious trend to seroconvert slowly. Seropositive ewes had a significantly lower reproduction rate and their lambs suffered from significantly higher death and lower growth rates, probably due to a reduced milk production, resulting in economic losses.

Animals↗

An assessment of the needs of family physicians for a rheumatology Continuing Medical Educational program: results of a pilot project.

OBJECTIVE: To assess the needs and determine the effect of a Continuing Medical Education (CME) program designed for primary care physicians on the management of osteoarthritis (OA). METHODS: The needs of potential CME consumers were determined using a standardized case recall questionnaire on the management of OA. A CME program was designed to specifically address identified needs, and the effect of the program was determined by repeat questionnaire by participants at 3 mo followup. RESULTS: Primary care physicians had a high rate of use of nonsteroidal antiinflammatory drugs (NSAID) and a proportionately low rate of use of analgesics. Physiotherapeutic modalities and local steroid injections were underused. There was a relatively low appreciation of potential side effects of therapeutic choices and possible risk factors for toxicity. After participating in the CME program, attendees demonstrated change in their therapeutic practices with an increased awareness of relative risks/benefits of NSAID vs analgesics. CONCLUSION: A case recall questionnaire format is a simple and inexpensive means of determining the need for developing a specific program for, and determining the effect of a CME program applicable to rheumatology CME activities for primary care physicians.

Anti-Inflammatory Agents, Non-Steroidal↗