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Relationship of periodontal disease and tooth loss to prevalence of coronary heart disease.

BACKGROUND: Studies relating periodontal disease to coronary heart disease (CHD) have provided equivocal results using tooth loss and/or clinical signs of periodontal disease as measures of periodontal exposure. METHODS: The purpose of this cross-sectional study was to evaluate the relationship of tooth loss and periodontitis to prevalent CHD at the Atherosclerosis Risk in Communities (ARIC) visit 4 using both tooth loss and clinical signs of disease in a population-based sample of 8,363 men and women aged 52 to 75 years from four U.S. communities. Each subject participated in a complete periodontal examination, assessment of missing teeth, assessment of prevalent CHD, and a number of laboratory tests and questionnaires. High attachment loss was defined as > or = 10% of sites with attachment loss > 3 mm and high tooth loss was defined as fewer than 17 remaining teeth. RESULTS: Individuals with both high attachment loss and high tooth loss (odds ratio [OR] 1.5, 95% confidence interval [CI] 1.1 to 2.0) and edentulous individuals (OR 1.8, CI 1.4 to 2.4) had elevated odds of prevalent CHD compared to individuals with low attachment loss and low tooth loss, while controlling for a number of traditional risk factors for CHD. CONCLUSIONS: These results suggest that tooth loss and periodontal disease are associated with prevalent CHD, but only when both are present. The weaker relationships between periodontal disease and CHD that have been found among older adults may be due to older adults having fewer teeth. Future longitudinal studies should be designed to ascertain the cause of tooth loss during follow-up.

Black or African American↗

The influence of prosthesis designs and loading conditions on the stress distribution of tooth-implant supported prostheses.

The aim of this study was to observe the influence of prosthesis design and loading condition on the stress distributions of tooth-implant supported prostheses. Six 2D finite element models, two reference models, and four experimental models were computed to simulate different prosthesis designs. Six different loading conditions were applied to investigate the stress distributions of tooth and implant, respectively. The stresses of reference models were considered as 100%; the stresses of experimental models at the same locations were compared with those of reference models. The stresses around implants were higher than those around teeth. When vertical loading was applied only on the implant, the stresses to both the implant and teeth were at their lowest. The highest stress to the tooth was in the model TTPF and the lowest in the model TPFF. The highest stress to the implant was in the model TPPF and the lowest in the model TPFF. These data indicated that the loading on the tooth-implant supported prosthesis was mainly supported by the implant. Minimizing the loading on the tooth decreased the stress to both the tooth and the implant. Adding fixtures as abutment was more effective in decreasing the stress than adding tooth as abutment in tooth-implant supported prosthesis.

Alveolar Process↗

[Tooth movement by biomechanical technique in orthodontic treatment].

The purpose of this study was to analyze tooth movement by measuring the electric impedance of the wire and by using the nonlinear finite element analysis. In this study, the HP4338A Milliohmmeter was used and the model consisted of a metal tooth, silicone bath, bracket, and orthodontic wire. Then, the two-dimensional finite elements were used and the model consisted of tooth, periodontal ligament, alveolar bone, bracket, and orthodontic wire. There were two analyses. The first was the contact nonlinear finite element analysis of elastic deformation in the displaced tooth at the slide points between the bracket and wire where two gap element areas existed, and the second was the material nonlinear finite element analysis of the stress relaxation in bone at the fixing points between the bracket and wire where two rigid element areas, differing from the gap element areas, existed. The results were as follows: 1. The linear proportion between the electric impedance and the orthodontic wire was found. Therefore very minute tooth movements became measurable with changes of the wire electric impedance. 2. During tooth movement, the stick between the bracket and the wire altered with the slip ones repeatedly. 3. The movement of the displaced tooth at the center of rotation was counterclockwise. 4. The movement of the displaced tooth at the bracket position was clockwise.

Biomechanical Phenomena↗

Diabetes, periodontal diseases, dental caries, and tooth loss: a review of the literature.

Diabetes mellitus, is a common chronic disease, and its prevalence in the United States, particularly type 2 diabetes, is increasing. Complications associated with diabetes impose a heavy burden on many people, especially among certain minority populations. Periodontal diseases, dental caries, and tooth loss also are common conditions in the United States, but their prevalence is generally decreasing. Nevertheless, among important subgroups of the population, particularly certain minority and economically disadvantaged groups, there is a disproportionately higher burden of periodontal diseases, dental caries, and tooth loss. This article reviews the post-1960 English-language literature on the relationship between diabetes and oral health, specifically focusing on periodontal disease, dental caries, and tooth loss. Substantial evidence exists to support the role of diabetes and poorer glycemic control as important risk factors for periodontal disease. Additionally, the evidence provides support for viewing the relationship between diabetes and periodontal diseases as bidirectional. However, additional research is necessary to firmly establish that treating periodontal infections can contribute to glycemic control management and possibly to the reduction of type 2 diabetes complications. The literature does not describe a consistent relationship between type 2 diabetes and dental caries. It reports increased, decreased, and similar caries experiences between those with and without diabetes. This review suggests that currently there is insufficient evidence to determine whether a relationship between diabetes and risk for coronal or root caries exists. Most of the reviewed studies reported greater tooth loss in people with diabetes. However, the differences were slight and not significant in several of the reports. Furthermore, this review of the association between diabetes and tooth loss reveals that valid population-based evidence generalizable to the US population is sparse. Further investigations of the association of diabetes with dental caries and tooth loss are warranted. If adverse effects of diabetes on dental caries and/or tooth loss are substantiated, the results of such studies would help design intervention studies to prevent or reduce the occurrence of dental caries and tooth loss in people with diabetes. These results also may affect existing clinical practice protocols and promote new public policy related to diabetes.

Blood Glucose↗

[The preventive effectiveness in reducing tooth decay and decalcification of different concentration of fluoride toothpaste for orthodontic patients].

OBJECTIVE: To investigate the preventive effectiveness in reducing tooth decay and decalcification of different concentration of fluoride toothpaste for orthodontic patients. METHODS: 86 patients were divided into the first test group and the second test group. The patients of the first test group brushed tooth with 1.1% sodium fluoride and acidulated phosphate gel. The patients of the second test group brushed tooth with 0.243% sodium fluoride in a silica base. The extent of facial tooth decay and decalcification of the twelve upper and lower teeth from right cuspid to left cuspid was scored blindly and independently by four observers after 12 months of product use. The scores were rated either one (having tooth cavity/decalcification) or zero (no tooth cavity/decalcification). Four observer's readings were averaged per tooth, and then per patient for the two treatment groups. RESULTS: After 12 months of product use, the mean caries score of the first test group was 0.326, and the mean caries score of the second test group was 0.490. There was significant difference between them. CONCLUSION: A gel system containing 1.1% sodium fluoride and acidulated phosphate provides a clinically better efficacy in reducing tooth decay and decalcification than does a toothpaste containing 0.243% sodium fluoride in a silica base under and adjacent to orthodontic brackets used in orthodontic therapy.

Dental Caries↗

[The effects of remain of residual tooth on retention of post-core crown system].

This study was aimed to assess the effects of remain of residual tooth on the retention of postpost-core was made,casted and cemented. The post-core was tested at the speed of 10 mm/min on the Instron4302, and the retention force was recorded. Other samples were made and subjected to the test for cohesion of polymethylmethacrylate and metal. The result showed that retention significantly increased with the adding of the residual tooth. When the length of post was longer than 8 mm and 1 mm was added to tooth remain, the difference in retention between the two groups was statistically significant. It was noted that there existed relationships of retention to length of post and tooth remain, of cohesion to length of post and tooth remain, and of frictiion resistence to length of post and tooth remain; moreover, the relevant linear regression equations were obtained. So during the tooth preparation of post-core system, the tooth tissue should be reserved as much as possible.

Crowns↗

[Effect of iodoform on development of cultured tooth-germs of newborn Syrian hamsters].

To examine the effect of iodoform, widely used as a component of filling sealer for root canals, on differentiation and development of tooth-germs, tooth-germs of second molars from newborn Syrian hamsters were cultivated overnight and treated with various concentrations of iodoform for 48 hours. They were subsequently transplanted into the cheek pouch of Syrian hamsters and were subjected to histo chemical examinations three weeks later. 86% of the seven tooth germs examined survived treatment with 1.0 microgram/ml iodoform, as determined by morphology of tooth-germs. The ratio of survival decreased with increasing doses of iodoform, e.g. 63%, 37%, and 13% for 3.3 micrograms/ml, 6.6 micrograms/ml and 10.0 micrograms/ml iodoform, respectively. In untreated tooth-germs, a similar level of survival was obtained with treatment using 1.0 microgram/ml iodoform. Although treatment with 1.0 microgram/ml iodoform showed a survival similar to untreated tooth-germs, the treatment induced a considerable level of aplasia of enamel and dentin in the dental crowns. Meanwhile, higher dose of iodoform was required for induction of aplasia or depression of the dental pulp or root dentain. These results indicate that iodoform over the dose of 1.0 microgram/ml is toxic to cultured tooth-germs of Syrian hamsters and inhibits differentiation or development of the tooth-germs with tissue specificity.

Animals↗

Allogeneic tooth transplantation in the dog.

Allogeneic tooth transplantation was evaluated as a functional and aesthetic treatment for dental fracture in the dog. Of 7 dogs that received tooth transplants, 5 were research animals and 2 were clinical patients. Canine teeth were transplanted immediately after extraction in the research dogs. Endodontic therapy had been performed on the affected canine tooth of one clinical patient. The other clinical patient had bilateral maxillary canine fractures 2 months earlier. One of the research dog transplants failed at 3 weeks as a result of improper surgical technique. Four of the research dogs had a solid implant for 18 months, after which time the dogs were euthanatized serially. All transplanted teeth were anchored firmly into the alveoli, but were nonviable. Root resorption, with bone replacement, was first noticed at 24 months. The transplanted tooth in the first clinical patient remained functional for 3 months, after which time the tooth was fractured. The right canine transplant in the second clinical patient failed by 3 months, probably because of preexisting periapical inflammation. The left transplanted tooth remains stable at 38 months. It was concluded that allogeneic tooth transplantation may have merit as a rapid and inexpensive method for replacement of fractured teeth in the dog. Function is compromised gradually as a result of root resorption and ankylosis, with tooth fracture likely to occur after 2 years.

Animals↗

Clinical application of the graphical analysis of tooth width discrepancy.

Mesiodistal tooth width discrepancies between the maxillary and mandibular teeth may be present in any dentition. A mismatch in width between the maxillary and mandibular teeth can have a pronounced effect on the occlusion by preventing the correct interdigitation of buccal teeth and the correct overbite/overjet relation of anterior teeth. No simple graphical method of analysis of tooth width discrepancy has previously been devised. The present graphical analysis of tooth width discrepancy has been developed to comprehensively assess new cases for tooth width discrepancy. The findings from the graphical analysis of tooth width discrepancy were invaluable as an aid in diagnosis and treatment planning. Diagnostic set-ups performed on each malocclusion supported the findings from the graphical analysis. The analysis provided the ability to visually recognise and localise the tooth or teeth causing the tooth width discrepancy. Computerisation of the graphical analysis of tooth width discrepancy will simplify and encourage its use in the overall diagnosis and treatment planning of all malocclusions.

Algorithms↗

A premaxilla with a supernumerary tooth indicating a developmental region with a variety of dental abnormalities: a report of nine cases.

The aim of this study was to elucidate whether a premaxilla with a supernumerary tooth has additional dental abnormalities. The study does not include premaxillas with a mesiodens, only premaxillas with parasagittally located supernumerary teeth. Radiographs from eight children, followed from 1 year and 5 months to 11 years and 5 months in the municipal dental health service in Denmark, were analyzed. One patient was seen only once. Dental abnormalities recorded included: invaginations on permanent incisors, resorption of roots of incisors, curved roots of incisors, delayed eruption, and delayed formation of roots. The study shows that there are dental abnormalities within the premaxillary region where the supernumerary tooth is located. This indicates that, apart from the supernumerary tooth, a more widespread deviation from normal conditions including tooth malformation, arrested eruption, and root resorption occur within the premaxillary region. The most important outcome of this study is that in the region with a supernumerary tooth the adjacent incisor shows delayed eruption after surgical removal of the supernumerary tooth. The deviations in root morphology, including root resorption, are not limited to patients who have had orthodontic treatment, but patients who did not receive orthodontic treatment also revealed deviations in root morphology. Therefore the treatment outcome can be different from the expected outcome.

Adolescent↗

Tooth structure loss apical to preparations for fixed partial dentures when using self-limiting burs.

STATEMENT OF PROBLEM: Burs with guide pins may be used to limit the depth of tooth preparation for fixed partial dentures. The effects of guide pins on tooth structure apical to the finish line after tooth preparation for fixed partial dentures has not been recorded. PURPOSE: This in vitro study recorded loss of tooth structure within 1.0 mm apical to the finish line of teeth prepared with straight cylinder and tapered cylinder self-limiting burs and one conventional bur. MATERIAL AND METHODS: Forty-five extracted human teeth were randomly divided into three groups. The facial surface of each tooth was prepared with two types of diamond burs with guide pins and a conventional diamond for the control. The surface was profiled before and after tooth preparation. Profiled surfaces were analyzed and the groups were compared using analysis of variance and the Tukey-Kramer HSD test (alpha = 0.05). RESULTS: No significant difference was recorded between the control group and the group prepared with a round-ended tapered cylinder self-limiting pin. However, there was a statistically significant difference between the control and cylindrical pin groups, and between the two groups prepared with self-limiting diamonds. CONCLUSION: This study revealed abrasion apical to the finish line of the preparation in all groups. The cylindrical guide pin group exhibited the greatest loss of tooth surface.

Analysis of Variance↗

The association of tooth lead content with dental health factors.

The purpose of this study was to determine the relationships of lead content in the human tooth with the prevalence of caries, dental plaque, pH of saliva, levels of Salivalis lactobacilli (SL) and Mutans streptococci (MS), degree of dental abrasion, tooth colour and toothbrushing frequency. A total of 220 teeth (one per person) were analysed using a microwave oven digestion procedure and lead content was measured by atomic absorption spectrometry. Tooth lead content followed a logarithmic-normal distribution and it increased with the prevalence of caries. Tooth lead concentrations were positively correlated with all the considered dental health factors except the pH of saliva, for which there was a significant negative correlation. Coloured teeth and teeth subject to abrasion showed the highest lead content. The highest number of colonies of SL and MS in saliva paralleled the highest lead tooth levels. Teeth obtained from irregular brushers presented higher tooth lead contents than subjects with a regular toothbrushing frequency. Multiple logistic regression analysis showed a significant association between tooth lead levels and dental plaque surface, Salivalis lactobacilli number, dental abrasion and dental colour. We conclude that accumulation of lead in teeth is associated with those dental health factors.

Adolescent↗

The effect of a tooth gingival transplantation on periodontal healing.

We investigated the effects of a tooth gingival transplantation (TGT) on autologous tooth transplantation using tooth with both periodontal ligament and gingiva. Stabilization period, degree of tooth mobility, and periodontal pocket depth (PPD) were compared with those of transplanted teeth using the conventional method (tooth with periodontal ligament). The subjects were 76 healthy adults (56 cases for the conventional method and 20 cases for TGT). Stabilization period of the tooth was shorter in the cases of TGT than that of the conventional method. Degree of tooth mobility was almost the same for TGT and the conventional technique. The value of PPD at 12 weeks after operation was better in the TGT group than in the conventional method group. The results for both stabilization period and PPD were better in TGT than in the conventional method, indicating low risk for periodontal disease in TGT.

Acrylic Resins↗

Dental development, dental age and tooth counts.

Emergence data on the 20 deciduous teeth and the first 29 permanent teeth were collected from 212 randomly selected urban Swedish children who were followed from birth to 18 years of age. The sex difference in the emergence of the deciduous teeth is less than one month, which is not statistically significant. Boys are consistently ahead of girls until the 17th deciduous tooth. From the 17th deciduous tooth on through most of the permanent dentition, girls are consistently ahead of boys. In the permanent dentition the sex difference ranges from 3 MO to 11 MO; these differences are statistically significant except for the 29th tooth. Reference data on dental age based on counts of 1-19 deciduous and 1-27 permanent teeth are tabulated and tooth emergence curves constructed. The tooth emergence curves can be used to express individual dental development in terms of standard deviation scores. Validity of dental age assessed by counts of permanent teeth is evaluated by a cross-sectional comparison with another sample of Swedish boys and girls. The mean difference between estimated age and chronological age is about one month in either sex. Precision of an individual estimate of dental development in terms of 95% confidence level (approximately equal to +/- 2 S.D.) varies from about +/- 4 months in the deciduous dentition to +/- 3 years in the permanent dentition. Assessment of dental development and dental age by means of tooth counts is a convenient and simple method, although it can only be applied at ages when emergence can be expected. It is especially useful in cross-sectional evaluations, as no serial data are required. In populations with a low incidence of caries the impact of such disturbing factors on emergence is correspondingly low, further increasing the validity of assessments of dental development based on tooth emergence.

Adolescent↗

Applications of surface-surface matching algorithms for determination of orthodontic tooth movements.

Orthodontic tooth movements are described as the differences between initial and final tooth positions. A computer based method for determination of tooth movements for different treatment methods was developed. A total of 20 casts of the upper jaw of patients treated with tooth positioners or fixed appliances were used as a basis for this study. Tooth movement was analysed on casts before (Ci) and after treatment (Cf). The casts were digitized either with a COMT or 3D laser scanning systems. After digitization, the models were superimposed in the palate by using a surface-surface matching algorithm. Tooth surfaces of the orthodontically moved teeth were segmented and determination of tooth movement was accomplished by matching the moved teeth from Ci to Cf. The resulting transformations delivered three dimensional information on translations and rotations. An accuracy of 0.2 mm in translations and 1 degree in rotations could be demonstrated, showing the different efficiency of treatment schemes.

Algorithms↗

Anomalies of tooth formation in hypohidrotic ectodermal dysplasia.

OBJECTIVE: The X-linked hypohidrotic ectodermal dysplasia (HED) is the most common type of ectodermal dysplasia. The clinical identification of possible heterozygous females can be difficult because of the varying degrees of clinical signs caused by X-chromosome inactivation. This study is the first to elaborate on anomalies of tooth formation found in a group of hemizygous males and heterozygous females with known ED1 mutations. These tooth anomalies may be used as dental biomarkers for heterozygous females, enabling an earlier diagnosis, and therefore, better treatment and genetic counselling. METHODS: Anomalies of tooth formation were examined using panoramic radiographs, dental casts and oral photographs in hemizygous males and heterozygous females who were identified by molecular genetic analysis. The results were compared to existing controls and normative data. RESULTS: All affected males had multiple missing permanent teeth and tooth malformations. The heterozygous females had a significantly higher frequency of agenesis of permanent teeth compared to normative data. The heterozygous females had an increased prevalence of tooth malformations and reduced tooth size, especially in the mesiodistal dimension. CONCLUSIONS: We conclude that observed anomalies of tooth formation may be used as dental biomarkers in the clinical identification of potentially heterozygous females.

Adolescent↗

Tooth wear in children with Down syndrome.

BACKGROUND: Several studies have described the impact that dental caries and periodontitis may have on the dentitions of individuals with Down syndrome, but there are few reports about the effects of tooth wear. This investigation aimed to compare the aetiology, prevalence and severity of tooth wear in 49 cytogenetically confirmed Down syndrome children with 49 non-Down syndrome controls. METHODS: This study involved three aspects: an oral examination, including obtaining dental impressions; a dietary analysis spanning three days; and a questionnaire seeking information about habits, medical problems and medications. Tooth wear severity was scored on a 4-grade scale (none-to-little; moderate; severe; very severe), while aetiology was classified as being due to attrition mainly, erosion mainly, or a combination of both. Double determinations established scoring method reliability and chi-square tests assessed associations between samples. RESULTS: Tooth wear was significantly more frequent (p<0.01) in the Down syndrome than the non-Down syndrome sample (67.4 per cent cf 34.7 per cent), with more of the Down syndrome children showing severe to very severe wear (59.2 per cent cf 8.2 per cent). Significantly more Down syndrome children (p<0.05) displayed a multifactorial aetiology of tooth wear, i.e., both attrition and erosion (46.7 per cent cf 28.6 per cent), although no particular dietary link was established. Gastric reflux and vomiting were reported in over 20 per cent of the Down syndrome sample. CONCLUSIONS: Given the potential consequences of high levels of tooth wear, associated with tooth grinding and an acidic oral environment in Down syndrome children, educational programmes aimed at increasing awareness of carers and health professionals are needed urgently.

Adolescent↗

A model for the prediction of tooth wear in individuals.

BACKGROUND: Easily applied, age-specific standards are useful in assisting clinicians to decide whether the extent of tooth wear observed in a given patient at a specific age is acceptable or whether intervention is indicated. METHOD: A simple method of scoring tooth wear and previously established mathematical relationships between tooth wear scores and age, provide the basis of a method for predicting tooth wear scores. In its most specific form, the method can be used to predict tooth wear scores for individual patients at subsequent ages. Alternatively, tables or graphs can be consulted to provide a less precise prediction of tooth wear that can assist clinicians to decide whether the amount of wear reflects high, moderate or low rates of wear at the specified age. CONCLUSION: In cases where there is no reason to believe that aetiological factors have changed significantly over time, data obtained from the methods described can assist clinicians to plan appropriate management for patients presenting with unacceptable levels of tooth wear.

Age Factors↗