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PubMed2002

Measuring teacher attitudes and expectations toward students with ADHD: development of the test of knowledge about ADHD (KADD).

OBJECTIVE: The attitudes, expectations, and behaviors of teachers toward children with Attention-Deficit/Hyperactivity Disorder (ADHD) may have a lasting impact on the academic self-efficacy and success of students with ADHD. Yet, to date there exists no standardized measure of teacher attitudes or expectations toward children with ADHD. The purpose of this study was to develop an instrument to measure teacher attitudes and expectancies toward children with ADHD. METHOD: The Test of Knowledge About ADHD (KADD) was constructed based on the error-choice method, which is an indirect method of attitude measurement. This psychometric approach was utilized to reduce patterns of response distortions that produce systematic errors in direct attitudinal assessment. Elementary school teachers (N = 103) completed the error-choice instrument. CONCLUSION: Results indicated adequate to good internal consistency reliability for the KADD for this sample, with a Cronbach's coefficient alpha of 0.82. Additionally, results yielded initial discriminant evidence to suggest that the KADD has construct validity for this sample. Implications for the use of this instrument in applied areas are discussed.

Adult↗

PubMed1999

Haplotype relative risk study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD): association of the high-enzyme activity Val allele with ADHD impulsive-hyperactive phenotype.

Attention deficit hyperactivity disorder (ADHD) is a developmental syndrome expressed along three domains: inattention, hyperactive-impulsive, and combined type. Both environmental and genetic factors contribute to the etiology of this complex disease. In the current investigation, a catechol-O-methyltransferase (COMT) polymorphism that codes for a high versus low enzyme COMT activity was examined using family-based methods for a role in ADHD. Using a haplotype relative risk design and a parent-to-proband allele transmission test with 48 ADHD triads, we found an association between COMT and illness (chi(2) = 4.72, p = 0.03, df = 1). In particular, the impulsive-hyperactive type of ADHD (excluding inattention) ascertained by Diagnostic and Statistical Manual of Mental Disorders (DSM IV) criteria (chi(2) = 8.34, p = 0.004, df = 1), by the Conners Teaching Rating Hyperactivity scale (Pearson chi(2) = 5.32, p = 0.02, df = 1) as well as by the Continuous Performance Test False Alarm scale (chi(2) = 2.78, p = 0.096, df = 1) were associated with the high enzyme activity COMT val allele. Similar results were obtained if genotype frequencies were compared. It should be noted that the association between the high-enzyme activity COMT val allele that increases CNS dopamine (and norepinephrine) clearance is consistent with the use of methylphenidate, an agent that increases dopamine (and norepinephrine) turnover, in the treatment of this disorder. These provisional findings suggest that newly developed COMT inhibitors such as tolcapone, applied in Parkinson's disease, might in due time be considered in the treatment of ADHD.

Adolescent↗

PubMed1997

Associations between ADHD and psychoactive substance use disorders. Findings from a longitudinal study of high-risk siblings of ADHD children.

This article investigates the relationship between attention-deficit/hyperactivity disorder (ADHD) and psychoactive substance use disorders (PSUD) in siblings of ADHD and normal-control probands and addresses issues of psychiatric comorbidity and gender. Using DSM-III-R structured diagnostic interviews and blind raters, the authors conducted a 4-year follow-up of siblings. ADHD and male gender predicted higher rates and an earlier onset of PSUD after adjusting for high-risk status, other psychiatric disorders, and age. Risk was particularly high if the siblings had ADHD plus conduct disorder. This study's findings confirms the authors' prior report high-lighting the importance of drug and alcohol prevention and cessation programs aimed at ADHD youth and their siblings, particularly those with comorbid conduct disorder.

Adolescent↗

PubMed2005

Executive functions and ADHD in adults: evidence for selective effects on ADHD symptom domains.

Dual-process models of attention-deficit/hyperactivity disorder (ADHD) suggest that both executive functioning and regulatory functions (e.g., processing speed) are involved and that executive function weaknesses may be associated specifically with symptoms of inattention-disorganization but not hyperactivity-impulsivity. Adults aged 18-37 (105 with ADHD, 90 controls) completed a neuropsychological battery. The ADHD group had weaker performance than did the control group (p<.01) on both executive and speed measures. Symptoms of inattention-disorganization were uniquely related to executive functioning with hyperactivity-impulsivity controlled. Inattention was associated with slower response speed, and hyperactivity-impulsivity with faster output speed. Results were not accounted for by IQ, age, gender, education level, or comorbid disorders. Findings are discussed in terms of developmental and dual-process models of ADHD leading into adulthood.

Adolescent↗

PubMedDate not supplied

The diversity of attention deficits in ADHD: the prevalence of four cognitive factors in ADHD versus controls.

The performance of participants with attention-deficit/hyperactivity disorder (ADHD) relative to control participants was measured on four tasks uniquely assessing the functions of selective attention, executive attention, sustained attention, and orienting of attention. The results showed that deficits in sustained attention were the most pronounced, characterizing most participants with ADHD and deficits in each of the other three functions characterized more than half of these participants. Different participants with ADHD revealed different clusters of attentional deficits. These results call for a revision of leading theories of ADHD that identify the core of the pathology as a sole deficit in executive functions.

Attention↗

PubMed2005

Inhibition, ADHD, and computer games: the inhibitory performance of children with ADHD on computerized tasks and games.

Contrary to empirical reports of inhibitory dysfunction in ADHD, parental reports suggest that when playing computer games, the inhibitory abilities of children with ADHD are unimpaired. This small-scale preliminary investigation into this phenomenon looks at inhibition of an ongoing response and activity exhibited by children with ADHD between 6 and 14 years old on two commercially available games, on the Conners's Continuous Performance Test II (CPT II), and on a more game-like version of the same task that incorporates characteristics commonly found in commercially available computer games. The performance of participants with ADHD on commercially available games is equivalent to that of typically developing participants and is significantly better on the more game-like version of the CPT II.

Adolescent↗

PubMed2005

Intervening to improve communication between parents, teachers, and primary care providers of children with ADHD or at high risk for ADHD.

This study examines interventions designed to improve communication between individuals who take care of children with ADHD. A teacher rating of 6,171 elementary school children identifies 1,573 children with ADHD or with high risk for ADHD. Parent interviews and information from teachers are collected on 243 children who are randomized into treatment and control conditions and followed for 39 months. The interventions consisted of group workshops and single one-on-one tutorials with parents, teachers, and providers about the evaluation and treatment of ADHD that stressed the need for communication between the three parties. There are few significant effects on communication that are short lived. Results suggest that the interventions are insufficient to cause significant increase in communication. Future attempts to improve parent-teacher-provider coordination should be continuing rather than single-session interventions.

Attention Deficit Disorder with Hyperactivity↗

PubMed1994

Visuospatial attentional shifts and choice responses of adults and ADHD and non-ADHD children.

18 adults, 17 ADHD children, and 18 non-ADHD children performed a choice-response task on which the spatial location of a target was sometimes compatible and sometimes incompatible with priming cues that varied between 50 and 1000 msec. Children's response latencies differed from adults' response latencies as a function of the delay between priming cue and target onset. A cost-benefit analysis indicated that valid stimulus cues facilitated performance and invalid stimulus cues impeded performance similarly for the three groups. Choice-response errors following invalid cues did not differ between ADHD and non-ADHD children; however, adults made more choice errors than children at 150-msec. and 300-msec. delay intervals. Developmental factors that may underlie differences between children's and adults' response speed and response accuracy are discussed.

Adolescent↗

PubMed2005

The Risk Society and attention deficit hyperactivity disorder (ADHD): a critical social research analysis concerning the development and social impact of the ADHD diagnosis.

This article reports the findings of a research study that used a critical social research methodology to review the increase in use of the diagnosis of attention deficit hyperactivity disorder (ADHD) and conceptualized the phenomenon within a theoretical framework based upon Beck's (1992, 1999) periodization of social change, the Risk Society. The study was qualitative in nature. Data were drawn from a wide range of sources including legitimating hearings, reports and studies, texts and seminal documents, field observations in schools and classrooms, and electronic discussion/bulletin board, and in-depth interviews with parents and teachers. The analysis used a critical framework to locate specific instances of claim and counter-claim and to set the historical context for understanding the "modern biological" method of intervention with children considered by parents and teachers as having ADHD. The findings of the study are structured in the context of risks. Further research will inform whether the risks become threats. Through exposure of silences, myths, contradictions and power relationships that create risks surrounding the ADHD phenomenon, it is hoped that discourse concerning the hegemonic medical model of ADHD in research and in the wider community will be further critically examined.

Attention Deficit Disorder with Hyperactivity↗

PubMed2007

A study of how socioeconomic status moderates the relationship between SNPs encompassing BDNF and ADHD symptom counts in ADHD families.

Recent animal research suggests that brain-derived neurotrophic factor (BDNF), may mediate response to different environmental stimuli. In this paper, we evaluated the possible role of BDNF as a moderator of attention deficit hyperactivity disorder (ADHD) in the context of different socioeconomic classes. We genotyped ten single nucleotide polymorphisms (SNPs) in and around BDNF in 229 families and evaluate whether there are SNP-by-socioeconomic status (SES) interactions for attention deficit hyperactivity. We developed three quantitative phenotypes for ADHD from nine inattentive and nine hyperactive-impulsive symptoms that were used in SNP-by-SES interaction analyses using a new methodology implemented in the computer program PBAT. Findings were adjusted for multiple comparisons using the false discovery rate. We found multiple significant SNP-by-SES interactions using the inattentive symptom count. This study suggests that different SES classes may modify the effect of the functional variant(s) in and around BDNF to have an impact on the number of ADHD symptom counts that are observed. The two exons within BDNF represent potential functional variants that may be causing the observed associations.

Attention Deficit Disorder with Hyperactivity↗

PubMed2005

Inferring candidate genes for attention deficit hyperactivity disorder (ADHD) assessed by the World Health Organization Adult ADHD Self-Report Scale (ASRS).

The present study tests the psychometric properties and validity of the German version of the World Health Organization Adult Attention Deficit Hyperactivity Disorder (ADHD) Self-Report Scale (ASRS), which is a short screening instrument for use in the general population. Furthermore, two candidate genes for ADHD, the COMT VAL158MET and the 5-HT2a T102C polymorphisms, were tested for associations with the ASRS subscales inattention and hyperactivity/impulsivity in N = 203 healthy subjects. The ordinal CFA yielded a two-factorial model corroborating the structure of the official English WHO version. Genetic analysis revealed an association between the VAL allele of COMT and the inattention scale (F(1, 201) = 7.20, p = 0.008), the hyperactivity/impulsivity scale (F(1, 201) = 4.30, p = 0.039), and the total ASRS scale (F(2, 201) = 7.64, p = 0.006) with highest scores in carriers of the MET/MET genotype. The C-allele of 5-HT2a was significantly associated with the hyperactivity/impulsivity scale (F(1, 201) = 5.52, p = 0.020) and the total ASRS scale (F(1, 201) = 4.21, p = 0.042) with highest scores in carriers of the TT genotype. The data provide evidence for the structural as well as for the external validity of the ASRS.

Attention Deficit Disorder with Hyperactivity↗

PubMed2003

Parenting of children with attention-defecit/hyperactivity disorder (ADHD): the role of parental ADHD symptomatology.

OBJECTIVE: The present study examined the relation between parental ADHD symptomatology and parent-child behavior among 46 mothers and 26 fathers of ADHD children. RESULTS: Fathers' self-reports of inattention and impulsivity were strongly associated with self-reports of lax parenting both before and after parent training, and with self-reports of overreactivity after parent training. Fathers' impulsivity was also associated with more arguing during audiotaped observations of parent-child interactions prior to parent training. Mothers' self-reports of inattention were modestly associated with self-reports of laxness before and after parent training. Prior to parent training, there were non-linear relations between mothers' inattention and observations of mother-child behavior, with mothers who reported moderate levels of inattention engaging in the most negative parent-child interactions. After parent training, these relations were linear, with the mothers who reported the most inattention engaging in the most negative parent-child interactions. These results were weakened but were generally still significant when parental depression and alcohol use were controlled.

Adult↗

PubMed2006

Predictors of adolescent functioning in girls with attention deficit hyperactivity disorder (ADHD): the role of childhood ADHD, conduct problems, and peer status.

Predictors of adolescent functioning were studied in an ethnically diverse sample of girls with attention deficit hyperactivity disorder (ADHD; n = 140) and age- and ethnicity-matched comparison girls (n = 88) who participated in naturalistic summer programs during childhood. Over a 5-year follow-up (sample retention = 92%; age range = 11.3-18.2 years), conduct problems were predicted by hyperactivity-impulsivity (HI) symptoms and noncompliance (NC). Academic achievement was predicted only by inattention symptoms, whereas school suspensions and expulsions were predicted by inattention symptoms (ADHD sample only), NC, and negative peer status. Substance use was predicted by NC and HI symptoms. Internalizing problems were predicted by HI symptoms, NC, and covert antisocial behavior. Finally, initial peer status was the only significant predictor of later negative social preference.

Adolescent↗

PubMed2005