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[Usefulness of alpha 2-adrenoceptor agonists and practical problems associated with their use in clinical anesthesia--II. Effects in regional anesthesia and analgesic effects for pain relief].

In the second part of this review, we summarized the effects of alpha 2-adrenoceptor agonists (clonidine and dexamedetomidine) in regional anesthesia and pain control, and evaluated their usefulness as anesthetic adjuvants and analgesics in the clinical settings. In addition, we referred to practical problems associated with their use.

Adjuvants, Anesthesia↗

Carotid endarterectomy using regional anesthesia.

The author has had considerable experience with the use of general anesthesia and regional anesthesia for patients undergoing carotid endarterectomy. His experience and a review of the literature indicate that the use of regional anesthesia significantly reduces the incidence of nonsurgical complications following operation. A particularly robust effect is placed on reducing cardiopulmonary complications.

Aged↗

Are anesthesia residency programs failing regional anesthesia? The past, present, and future.

BACKGROUND: A survey of anesthesia training programs in 1980 reported the use of a regional anesthetic technique in 21.3% of cases. Since that time, numerous changes have occurred in anesthesia residency programs. This survey was conducted to assess the impact these changes have had on the use and teaching of regional anesthetic techniques in residency training programs. METHODS: All anesthesia residency program directors were requested to send blinded copies of their residents' 1989-1990 American Board of Anesthesiology Annual Training Report Forms. Data from responding programs were compared to similar data from 1980, and analyzed for factors expected to influence the use of regional anesthesia during training. RESULTS: The use of regional anesthesia in residency training programs has increased from 21.3% in 1980 to 29.8% in 1990, primarily because of a two-fold rise in the use of epidural anesthesia. The use of regional anesthesia is strongly correlated with a resident's exposure to obstetric anesthesia and pain consultations. Wide variability between residency programs remains. CONCLUSION: Some training programs continue to fail to provide adequate regional anesthesia exposure to train residents fully in these techniques, despite the overall increased use of regional anesthesia.

Anesthesia, Conduction↗

[Georg Perthes--a pioneer of modern regional anesthesia technics?].

In regional anesthesia, the localization of peripheral nerves and plexuses is possible by means of mechanical or electrical stimulation. Electrical stimulation for this purpose was first described in 1912 by the surgeon Georg Perthes (1869-1927) of Tübingen, who reported his own experiences. The original description and results of electrostimulation are transposed upon a modern point of view of regional anesthesia.

Anesthesia, Conduction↗

[Differences in IgM increase following operations in general anesthesia and paraspinal regional anesthesia].

The serum immunoglobin levels of 74 patients with a prosthetic hip operation were studied. 36 patients received general anaesthesia with thiopental sodium, succinylcholine, alcuronium and halothane, whereas 38 patients were given a catheter epidural anaesthesia (CEA) with bupivacaine. Both collectives were subdivided into four groups, in whom the loss of blood was substituted by either human albumin 5%, dextrane, gelatine, or hydroxyethyl starch. Patients with a general anaesthesia had a high increase in serum IgM on the 7th day after operation, whereas there was no increase in the patients who had received CEA. In all the other parameters there was no difference between the various anaesthetics; likewise, the individual volume substitution management procedures did not produce differences in these parameters. IgM elevation is interpreted as a reaction to an affection of the tracheo-bronchial system; this reaction did not occur with the CEA group. The cause of the reaction is the interaction of immunomodulating drugs, and changes in ventilation that lead to an activation of the immune system.

Anesthesia, Epidural↗

Views of obstetric patients who refuse regional anesthesia in cesarean section.

BACKGROUND: Regional anesthesia for cesarean section has gained widespread popularity. However, there are still a good few of obstetric patients who refuse it. This study was to investigate the reasons for refusing regional anesthesia in order to gain some insights into the attitudes and concerns of patients. METHODS: Three hundred and twenty-four obstetric patients scheduled for Cesarean section were interviewed just before entering the operating room. They were asked to give one or two reasons for refusing regional anesthesia. RESULTS: Two hundreds of them refused regional anesthesia. The most frequent reasons were apprehension of witnessing the operation (auditory or visional) (45.42%) and fear of backache following regional anesthesia (14.58%). CONCLUSIONS: Anesthesiologists should be aware of patients' feeling or concern and could be capable and willing to discuss with them the relevant problems.

Adolescent↗

[Regional anesthesia today--possibilities and limits: introduction (author's transl)].

The various procedures of regional anesthesia were widely used before the introduction of intratracheal anesthesia; thereafter, it was replaced by the today commonly used general anesthesia. Regional anesthesia nonetheless plays an important role, primarily in outpatient treatment, because a large number of surgical departments still have no anesthesiologist on the staff. Often the surgeon is responsible for both the operation and the anesthesia. Indications, risks, and complications including legal problems related to regional anesthesia are discussed.

Anesthesia, Conduction↗

Brain-stem anesthesia as a complication of regional anesthesia for ophthalmic surgery.

Brain-stem anesthesia is a serious complication of orbital regional anesthesia that may occur when the injected local anesthetic agent gains access to the central nervous system by direct spread from the apex of the orbit via submeningeal pathways. In most studies the reported incidence rate during retrobulbar block is one case per 350 to 500 patients. Failure to recognize the condition or to treat it adequately may be life threatening. Treatment includes reassurance, intravenous administration of fluids, pharmacologic circulatory support or suppression of convulsions, and cardiopulmonary resuscitation. With proper treatment complete recovery is the rule. In all situations in which orbital block is to be done, basic cardiopulmonary resuscitation equipment and personnel familiar with its use are essential. Monitoring of the blood pressure, electrocardiography and pulse oximetry should be routine. Having the globe in primary gaze renders the optic nerve less vulnerable, and avoidance of deep penetration of the orbit is of great importance.

Anesthesia↗

Thyroid and parathyroid surgery performed with patient under regional anesthesia.

Thyroid and parathyroid surgery is usually performed with the patient under general anesthesia; however, for selected patients regional anesthesia may be preferable. Between September 1977 and March 1986 regional anesthesia was used successfully as the sole anesthetic technique in 17 patients who underwent thyroid surgery and two patients who underwent parathyroid surgery. Procedures included two total thyroidectomies, 14 lobectomies or lobectomies with isthmusectomies, and one isthmusectomy. These 17 operations represent approximately 5% of the thyroid operations performed by the senior surgeon over the corresponding time. One patient underwent combined completion thyroidectomy and parathyroidectomy, and another patient underwent successful parathyroidectomy under regional anesthesia. In two additional patients, procedures could not be completed under regional anesthesia alone. In one of these two patients regional anesthesia appeared to effect a transient recurrent nerve paralysis. The indications for use of regional anesthesia have been primarily patient preference and associated cardiac or pulmonary disease. We now consider as contraindications to regional anesthesia patient apprehension about the technique, deafness, high spinal cord injury, recurrent laryngeal or phrenic nerve palsy, and allergy to local anesthesia. During this period, from 1977 to 1986, our administration of regional anesthesia has evolved from bilateral deep and superficial cervical plexus blocks to bilateral superficial blocks alone using bupivacaine with epinephrine, 1:200,000.

Adult↗

Guidelines for regional anesthesia fellowship training.

BACKGROUND: The number of regional anesthesia fellowships has grown over the past 2 decades. There currently exist no guidelines for what constitutes ideal regional anesthesia fellowship training. METHODS: Regional anesthesia fellowship program directors and other advocates of regional anesthesia were invited to participate in a collaborative project to establish a standardized curriculum for regional anesthesia fellowships. Guidelines were created based on the existing template of Accreditation Council of Graduate Medical Education program requirements for residency education in anesthesiology. The resulting draft guidelines were distributed at a meeting of the program directors, who were then asked to forward all comments and relevant training material from their respective institutions to a coordinating institution. RESULTS: All received materials were reviewed, and selected components were collated into a consensus document, which was then reviewed, modified, and eventually approved by the program directors over a 2-year series of meetings. The program directors agreed to adopt the guidelines as their fellowship curriculum and to evaluate their effectiveness in 2 years' time. CONCLUSIONS: The intent of these initial guidelines is to improve the quality and consistency of regional anesthesia fellowship training. The creation process also led to an affirmation of the directors' commitment to continued dialogue for the purpose of facilitating the exchange of ideas among programs.

Anesthesia, Conduction↗

Lumbar plexus in children. A sonographic study and its relevance to pediatric regional anesthesia.

BACKGROUND: Pediatric regional anesthesia has gained increasing interest over the past decades. The current study was conducted to investigate the lumbar paravertebral region and the lumbar plexus at L3-L4 and L4-L5 by means of sonography to obtain fundamentals for the performance of ultrasound-guided posterior lumbar plexus blocks. METHODS: Thirty-two children (12 boys, 20 girls) with American Society of Anesthesiologists physical status I or II were enrolled in the current study. The lumbar paravertebral region was visualized at L3-L4 and L4-L5 on two corresponding posterior sonograms (longitudinal, transverse). The lumbar plexus had to be delineated, and skin-plexus distances were measured. In a series of five pediatric patients undergoing inguinal herniotomy, ultrasound-guided posterior lumbar plexus blocks at L4-L5 were performed. RESULTS: The children were stratified into three age groups (group 1: > 3 yr and </= 5 yr; group 2: > 5 yr and </= 8 yr; group 3: > 8 yr and </= 12 yr). The lumbar plexus could be delineated at L3-L4 and L4-L5 in 19 of 20 cases in group 1, in 17 of 20 cases in group 2, in 22 of 24 cases at L3-L4 in group 3, and in 16 of 24 cases at L4-L5 in group 3. In all patients, the lumbar plexus was situated within the posterior part of the psoas major muscle. Skin-plexus distances showed statistical significant differences between groups 1 and 3 and between groups 2 and 3. The strongest positive correlation existed between skin-plexus distances and the children's weight. Ultrasound guidance enabled safe und successful posterior approaches to the lumbar plexus, thus resulting in effective anesthesia and analgesia of the inguinal region. CONCLUSIONS: Sonography of the lumbar plexus in children proved to be feasible. Skin-plexus distances correlated with the children's weight rather than with their age. The sonographic findings were fundamental for the performance of successful ultrasound-guided posterior approaches in a small group of pediatric patients.

Aging↗

Regional anesthesia: is it safer?

This article provides an overview of the current status of general anesthesia and regional anesthesia techniques including complications occurring after using these techniques. The advantages, disadvantages, mortality, and morbidity are described for these two techniques.

Anesthesia, Conduction↗

Cardiac outcome after peripheral vascular surgery. Comparison of general and regional anesthesia.

BACKGROUND: Despite evidence that regional anesthesia may be associated with fewer perioperative complications than general anesthesia, most studies that have compared cardiac outcome after general or regional anesthesia alone have not shown major differences. This study examines the impact of anesthetic choice on cardiac outcome in patients undergoing peripheral vascular surgery who have a high likelihood of associated coronary artery disease. METHODS: Four hundred twenty-three patients, between 1988 and 1991, were randomly assigned to receive general (n = 138), epidural (n = 149), or spinal anesthesia (n = 136) for femoral to distal artery bypass surgery. All patients were monitored with radial artery and pulmonary artery catheters. Postoperatively, patients were in a monitored setting for 48-72 h and had daily electrocardiograms for 4-5 days and creatine phosphokinase/isoenzymes every 8 h x 3, then daily for 4 days. Cardiac outcomes recorded were myocardial infarction, angina, and congestive heart failure. RESULTS: Baseline clinical characteristics were not different between anesthetic groups. Overall, the patient population included 86% who were diabetic, 69% with hypertension, 36% with a history of a prior myocardial infarction, and 41% with a history of smoking. Cardiovascular morbidity and overall mortality were not significantly different between groups when analyzed by either intention to treat or type of anesthesia received. In the intention to treat analysis, incidences of cardiac event or death for general, spinal, and epidural groups were 16.7%, 21.3%, and 15.4%, respectively. The absolute risk difference observed between general and all regional anesthesia groups for cardiac event or death was -1.6% (95% confidence interval -9.2%, 6.1%) This reflected a nonsignificant trend for lower risk of postoperative events with general anesthesia. CONCLUSIONS: The choice of anesthesia, when delivered as described, does not significantly influence cardiac morbidity and overall mortality in patients undergoing peripheral vascular surgery.

Aged↗

Regional anesthesia in children.

Regional anesthesia employing the spinal, epidural, or caudal approach was used to anesthetize 200 children, varying in age from 17 days to 15 years. Lidocaine in concentrations varying according to age was used. Ketamine (1 to 2 mg./kg.) was given in the majority of cases to ensure a quiet patient prior to block. No major anesthetic complications or deaths were attributable to the anesthetic technic. The caudal approach proved easiest.

Abdomen↗

Ketamine for intravenous regional anesthesia.

We studied ketamine intravenous regional anesthesia of the upper extremity in volunteers using concentrations of 0.5%, 0.3%, and 0.2%. Ketamine 0.5 and 0.3% produced adequate intravenous regional anesthesia. Anesthesia was inadequate when a 0.2% concentration was used. However, although the 0.3% concentration provides complete sympathetic, sensory, and motor blockade when injected into the isolated extremity, unpleasant psychotomimetic effects after the release of the tourniquet limit the usefulness of this use of ketamine. Ketamine cannot be recommended for intravenous regional anesthesia unless these unpleasant side effects are abolished or controlled by means of pharmacologic adjuvants.

Adult↗

[Importance of the needle in regional anesthesia].

The safety of regional anesthesia lies on a set of factors, namely, selection of the adequate technique, skill and proper training from the part of anesthesiologists and use of right equipment. The needle, as a prolongation of the hand of the anesthesiologist, must provide references in technique either by itself or joined to an objective method of nerve localization; this will result in a high percentage of success without iatrogenesis. We have reviewed 1,132 cases of regional anesthesia and grouped them into: intradural anesthesia, epidural anesthesia, and plexus anesthesia. We have evaluated the equipment used according to the success and iatrogenesis directly produced by the needle. Results were analyzed by Fisher's exact test and were statistically significant in the three groups, a fact that would indicate some specificity of the characteristics of the needle in each group of techniques. It would seem reasonable to adopt those techniques appearing to be the most efficacious after analysis in order to increase percentage of success and achieve the greatest safety in the clinical practice of anesthesiologists.

Anesthesia, Conduction↗