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[The mechanism of topical applied ion supplemented acidulated phosphate fluoride gel effects on dental enamel demineralization: an in vitro study].

The present study was carried out on dental enamel to describe surface changes in the scanning electron microscope and crystallites changes in the high-resolution transmitted electron microscope as related to treatments of topical applied ion supplemented acidulated phosphate fluoride (APFI) gel and artificial caries agent demineralization in vitro, which imitated in vivo with pH- cycling condition. Our data suggest that topical application of APFI gel produce some CaF2 spheres on the surface of enamel and some fluoride-containing apatites in dental enamel. The latter are considered as result of F- and CaHPO4 or hydroxyapatites. The essence of chemical reactions are discussed. The results confirm that enamel treated with APFI gel becomes more resistant to artificial caries agent and electron radiation damage.

Acidulated Phosphate Fluoride↗

Effect of self-brushing with acidulated phosphate fluoride (pH 5.6) on dental caries in children.

The aim of this work was to study the effect of a preventive program on the dental plaque and on the caries incidence in school children. The program comprised weekly supervised self brushing with acidulated phosphate fluoride (APF) gel (pH 5.6; concentration: 4520 ppm of ion F-). The program involved 240 children of 1st., 3rd and 5th grade of a primary school in the City of Buenos Aires (Argentina). The population was divided in 2 groups: A (experimental) and B (control). Ninety children from both groups (45 experimental and 45 control) were submitted to baseline clinical examination (DMFT and plaque index) and microbiological analysis (total streptococci, St mutans and St. mutans and St. mutans percentage). Group A was then submitted to a preventive program which included self brushing with APF gel (4520 ppm of ion F-). The 90-children sample was monitored after 1 and 2 years of program. Results were statistically processed and they revealed the following: a--DMFT was significantly greater in the control group than in the experimental group after 1 and 2 years of program; b--an 81.43% reduction in caries increment rate at the end of the 2-years program in the experimental group as compared to the control group; c--a rise in the number of colonies of total streptococci and of St. Mutans; d--a reduction in the % of St. mutans in the total streptococci flora in the plaque of children in the experimental group; e--the presence of St. mutans colonies featuring a rough surface; f--the effectiveness of the program in the modifying the profile of the diagnosed dental pathology.

Acidulated Phosphate Fluoride↗

The ability of 1.23% acidulated phosphate fluoride gel to inhibit simulated endogenous erosion in tooth roots.

BACKGROUND: Endogenous dental erosion is that produced by contact of gastric acids with tooth structure. It may affect exposed root cementum/dentine as well as coronal enamel, causing marked loss of mineral. The aim of this study was to determine whether 1.23 per cent acidulated phosphate fluoride gel, if applied to the surface cementum at certain intervals during an erosive acid challenge, could provide any protection against demineralization. MATERIALS AND METHODS: Roots of preserved extracted human teeth were painted with a water and acid resistant varnish, leaving two windows (3x1mm) of exposed dentine. These were placed in a solution containing 0.06MHCl and 2.2mMCaHPO4, which has been shown to simulate gastric acid when it meets the tooth surface. The roots were placed in the erosive solution unprotected (controls), or subject to APF application for four minutes prior to and every 10, 30 or 120 minutes during the erosive challenge. Roots were removed at either 6 or 12 hours, washed thoroughly and cut into 120microm thick sections. Depths of demineralization were measured using an optical graticule under polarized light microscopy. RESULTS: A high level of protection was provided when the roots were coated with APF gel every 10 or 30 minutes. CONCLUSIONS: APF gel will partially inhibit endogenous erosion of roots for up to 30 minutes if applied, for example, the night before a morning reflux episode. This should be considered along with other erosion control or reduction procedures for patients suffering from the effects of endogenous erosion.

Acidulated Phosphate Fluoride↗