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At least 55 records · Page 3Linked to original sources
PubMed1988

[The aerobic intestinal flora of the microchiropteran bat Chaerephon pumila in Madagascar].

From stools of 88 malagasy insect eater bats Chaerephon pumila, a large amount of bacterial strains were isolated. Twenty different species were recognized, most of them belonged to Enterobacteriaceae family. Eight strains were identified as Salmonella enterica subsp. enterica O48: -; 1.5, despite many atypical characters. Strains of Salmonella enteritidis, Koserella trabulsii, Kluyvera sp., ODC negative Serratia marcescens, atypical Hafnia alvei... were also identified.

Animals↗
PubMed1984

[Ultrastructure of freshly isolated strains of Bordetella pertussis].

The study of the electronograms of B. pertussis strains isolated in the foci of pertussis revealed the existence of the morphological variants of these cells, differing in the character of the cell wall, the state of the cytoplasm, the presence of amorphous inclusions of medium electron-optical density. The morphological variants did not correlate with the character of B. pertussis colonies isolated from blood-charcoal agar. The ultrastructure of the cells belonging to the second morphological variant was similar to that of the cells from the museum strain, altered by tetracycline treatment in the course of the experiment.

Atypical Bacterial Forms↗
PubMed1976

Bacterial variants: etiologic agent in Crohn's disease?

Bacterial variants of Pseudomonas maltophilia and Pseudomonas-like bacteria were recovered from tissues removed during the surgical treatment of three successive patients with Crohn's disease and from one patient with clinical and pathological features of both Crohn's disease and chronic ulcerative colitis. Bacterial variants were not cultured from colonic specimens of one patient with classical features of chronic ulcerative colitis and two patients with adenocarcinoma of the colon. The findings suggest that a relationship exists between variant bacteria and the pathogenesis of Crohn's disease.

Atypical Bacterial Forms↗
PubMed2002

[Rheumatologic manifestations of Lyme borreliosis].

PURPOSE: Lyme borreliosis is a multisystemic infection caused by the spirochaete Borrelia burgdorferi. In European endemic areas like northeast France, articular manifestations are, after neuroborreliosis, the most frequent extra-cutaneous features observed. Among the pathogenic species of Borrelia, Borrelia burgdorferi sensu stricto is the most frequently identified during Lyme arthritis, but others species also seem to be involved. CURRENT KNOWLEDGE AND KEY POINTS: The diagnosis of Lyme arthritis is usually based on combined clinical data and serological laboratory tests. In atypical forms, detection of bacterial DNA could be useful. While mechanisms involved in acute Lyme arthritis are beginning to be better understood, the pathogenesis of chronic arthritis, which concerns about 10% of the patients, remains unknown. Two hypotheses are proposed to explain the prolonged evolution of the articular disease: a chronic persistence of Borrelia burgdorferi, which evades the host immune system within the joint and/or an autoimmune mechanism by molecular mimicry. The antibiotic therapy is codified in acute arthritis, but is not really adapted in chronic Lyme arthritis or post-Lyme syndrome. FUTURE PROSPECTS AND PROJECTS: To prevent the disease, the vaccine available in the United States does not offer complete protection and is not useful in Europe since the species heterogeneity is important for the outer surface protein A. A better understanding of Lyme disease pathogenesis can subsequently lead to new therapeutic or preventive approaches.

Acute Disease↗
PubMed2000

[A Carnobacterium-like organism isolated form a patient with multiple bacterial synergistic gangrene].

An atypical lactic-acid producing gram positive rod Y6 strain was studied in this report, which was isolated form clinic sample of a patient with multiple bacterial synergistic gangrene, and could not be identified by routine method. A 1.5 kb of 16S rDNA of Y6 strain was synthesized and sequenced. Comparative 16S rDNA sequence analyses revealed that stain Y6 is most closely related to the genus of Carnobacterium. The overall similarity value between Y6 strain and Carnobacterium species are 93% to 97%. The signature nucleotides in 16S rDNA primary sequence of strain Y6 and that of genus of Carnobacterium were identical. The biological features of Y6 strain are very similar to that of Carnobacterium, such as lactic acid as main end product of in PYG broth, no gas produced form fermentation of glucose, catalase negative, no motility. Data suggested that Y6 strain is very similar to the genus of Carnobacterium, of which no strain has been isolated form clinical sample so far. Based on the results obtained, we names Y6 strain as Carnobacterium-like organism.

Base Sequence↗
PubMed1984

[Considerations on atypical acute bronchopneumopathies].

The cases were studied of 109 patients admitted to the 2nd General Medical Division of the Umberto I Hospital in Turin in the course of a year. The study revealed 99 bacterial infections and 10 atypical forms including 7 mycoplasma pneumoniae and 3 virus infections. The importance of suspecting atypical pneumopathies is therefore emphasised and despite the technical difficulties that may at times arise, tests for the less common aetiological agents are recommended.

Acute Disease↗
PubMed1986

Amnesia as a presenting symptom in subacute bacterial endocarditis.

A 33-year-old woman presented with an atypical form of amnesia. The amnesia completely resolved after treatment with intravenous penicillin for subacute bacterial endocarditis secondary to a viridans streptococcus. Neuropsychiatric presentations of bacterial endocarditis and the unique aspects of this case are discussed.

Adult↗
PubMed2000

Unusual presentations of infection in neutropenic patients.

Neutropenic patients may have unusual presentations of infection because of their inability to mount an adequate inflammatory response and their susceptibility to infection caused by less virulent organisms. About 60% of febrile episodes are associated with no other signs and symptoms and no infecting organism can be identified, yet most respond to antibacterial therapy. If not treated promptly, infection in neutropenic patients can progress rapidly. Unusual sites of infection include typhlitis, perirectal infections and atypical forms of cellulitis.

Bacterial Infections↗
PubMed2004

Whipple's disease.

Whipple's disease is a rare multisystemic infectious disorder affecting predominantly middle-aged men. Clinical manifestations are very variable with a very long, insidious, prediagnostic course. Weight loss, chronic diarrhea, arthralgias, and low-grade fever are characteristic features in most patients. Although gastrointestinal compromise is very common, atypical clinical forms are being increasingly recognized. Although a bacterial cause was strongly suggested for many years, the infectious agent was elusive until recently. The bacillus that was classified as an actinomycete was named Tropheryma whipplei and has singular characteristics. It presents affinity for the periodic acid-Schiff stain, but it is negative for Ziehl-Neelsen staining and has a characteristic trilamellar cell wall. Its genetic material has been recently sequenced, and culture was finally performed on a human fibroblast cell line. Pathological specimens show macrophage infiltration with mostly intracellular invasion of live bacteria. Immunologic factors, such as a subtle defect of cellular immunity possibly specific for the Whipple's bacterium, are believed to play a role in pathogenesis. The diagnosis requires the histologic assessment of diseased tissue, showing the characteristic infiltration, as a first approach, and confirmatory tests such as electron microscopy and/or polymerase chain reaction. Antibiotic treatment is mandatory and leads to a rapid clinical improvement and remission in most patients. Although the rationale for treatment is largely empiric, current recommendations include a 2-week parenteral therapy (third generation cephalosporin) followed by a long-term therapy with trimethoprim-sulphamethoxazole. This approach has been shown to reduce the number of relapses and was effective for prevention and/or treatment of the neurologic compromise.

Anti-Bacterial Agents↗
PubMed1998

Clinical and bacteriologic study of eighty-six patients with systemic lupus erythematosus complicated by infections.

OBJECTIVE: To investigate the clinical and bacteriologic features of patients with systemic lupus erythematosus (SLE) complicated by bacterial and/or fungal infections. METHODS: Statistical analysis was made on basis of the clinical and bacteriologic data of 86 patients with SLE complicated by bacterial and/or fungal infections. RESULTS: One hundred and thirty-three episodes of infections occurred in 86 patients with SLE, in which 51.13% were nosocomial infections and 76.69% occurred in the blood system, respiratory tract, lungs and urinary tract. Gram-negative bacilli, gram-positive cocci, fungal and other bacterial infections accounted for 39.85%, 31.58%, 18.80% and 9.77%, respectively. In the bacterial infections, 18.52% were caused by L-form bacteria and more than 60% of the patients had no apparent toxic manifestations. The odds ratio (OR) of infection increased significantly in patients with damaged functions of the heart, lungs and kidneys, and in those who received high-dosage steroids. CONCLUSIONS: Patients with SLE tend to develop nosocomial infections with gram-negative bacilli which are the most common pathogens. The clinical manifestations of the infection are atypical. Careful inspection and monitoring, timely collecting the specimens for L-form bacterial culture can reduce misdiagnosis and missed diagnosis of the infection.

Adolescent↗