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Mitral valve replacement: a 10-year follow-up of non-cloth-covered vs. cloth-covered caged-ball prostheses.

The timing of operation and the selection of prosthesis depend upon the evaluation of long-term results at 5 years and beyond. From 1965 to 1975, 290 patients had isolated mitral valve replacement with currently used prostheses, resulting in a 6.6% operative mortality and 64% relative survival at 10 years. In considering mortality, the results obtained with both series of valves were combined and a search made for significant differences in preoperative variables between the operative deaths and operative survivors. The significant variables for operative mortality were valve model, preoperative functional class, pump time, and the presence or absence of right ventricular hypertrophy on electrocardiography. There were significant differences in long-term survival only with regard to preoperative functional class, pulmonary vascular resistance, and pump time. Exponential curves were fitted to the event-free rates, and long-term results were then extrapolated. The 10-year projection of the percentage of patients alive and free of embolus (disregarding transient ischemic attacks) for the Model 6310-6320 (50%) was similar to that actually observed for the Model 6120 (46%). Although further experience may show one prosthesis more effective than the other, statistical extrapolations suggest continued comparable performance.

Female↗

Sweat responses to pesticide-proof clothing influenced by textile materials.

Themoregulatory responses were compared at an ambient temperature of 30 degrees C and a relative humidity of 50% between two kinds of protective clothing for pesticide spraying. One was made of nylon with wet coating polyurethane (A) and another was made of cotton with water repellent finish (B). The clothing ensemble was composed of a short-sleeved cotton shirt, long cotton underpants, cotton socks, shoes and the protective clothing. Five young female adults served as subjects. They took a rest with protective clothing ensemble for 15 min and then walked on a motor-driven treadmill (80m/min, 5% uphill grade) for 40 min, followed by 20-min rest. The increase of forearm sweat rate was higher in clothing A than in clothing B in 4 out of 5 subjects, although the average values were not significantly different. The total sweat rate of the whole body was also significantly larger in clothing A. Mean skin temperature and local skin temperatures in the arm, the chest and the thigh were significantly higher in clothing A than in clothing B. Clothing microclimate humidity was significantly higher in clothing A, while clothing microclimate temperature tended to be higher in clothing A. Individual observations about thermal, humidity and comfort sensation disclosed that the sensation was improved as a whole in clothing B. Local sweat rate was linearly related to mean body temperature and the regression line for clothing A was located above that for clothing B in 4 out of 5 subjects.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗