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At least 55 records · Page 3Linked to original sources
PubMed2000

Late aortic homograft valve endocarditis caused by Cardiobacterium hominis: a case report and review of the literature.

An unusual case of Cardiobacterium hominis endocarditis involving an aortic homograft valve is presented. Although the patient was young (a 17 year old man) and showed few of the characteristic features of the disease, the report does illustrate a number of the problems associated with this illness and highlights the need for the careful assessment of apparent culture negative endocarditis. The organism itself is susceptible to most antibiotics but further treatment, including surgery, may be necessary. Patients must therefore be examined repeatedly and assessed for haemodynamic deterioration, valve destruction or embolic phenomena. Homograft valve replacement may offer some benefits in the setting of aortic valve endocarditis and is therefore an attractive option in this situation.

Adolescent↗
PubMed1977

Endocarditis due to Cardiobacterium hominis.

A case of bacterial endocarditis was caused by Cardiobacterium hominis in a 41-year-old man with mitral and aortic incompetence due to a previous episode of rheumatic fever. The main distinguishing characteristics of C. hominis are described, and the incidence of endocarditis is reviewed. After six weeks of treatment with effective bactericidal chemotherapy a microbiological cure was achieved and the patient successfully underwent mitral valve replacement and aortic valve plication.

Adult↗
PubMed1979

Endocarditis due to strain of Cardiobacterium hominis resistant to erythromycin and vancomycin.

Endocarditis caused by Cardiobacterium hominis was observed in a penicillin-allergic patient with a prosthetic cardiac valve who had received prophylactic therapy with erythromycin for dental extractions. The organism was resistant to erythromycin and vancomycin, with minimal inhibitory concentrations of 12.5 microgram/ml and 25 microgram/ml, respectively, but was sensitive to penicillin G, tetracycline, cephalexin, and cefaclor. This case suggests that currently recommended antibiotic prophylactic therapy for endocarditis, especially in penicillin-allergic patients, may be inadequate for unusual pathogens such as C hominis.

Bacteria↗
PubMedDate not supplied

[A case report of Cardiobacterium hominis endocarditis].

We here report a case of endocarditis due to Cardiobacterium hominis in a 53-year-old patient, who presented with large vegetations on the mitral valve. Good cooperation between clinicians and microbiologists and an efficient automated blood culture system were the decisive factors in establishing the diagnosis. Early and appropriate treatment prevented the septic embolisms often observed in this pathology.

Amikacin↗
PubMed1991

Prosthetic valve endocarditis due to Cardiobacterium hominis occurring after upper gastrointestinal endoscopy.

Bacterial endocarditis secondary to endoscopic procedures has been convincingly documented in only four cases. We describe a case of prosthetic valve endocarditis due to Cardiobacterium hominis that developed after upper gastrointestinal endoscopy. Because of this, we recommend subacute bacterial endocarditis prophylaxis in patients who have a prior history of endocarditis or valve replacement.

Aortic Valve↗
PubMed1990

[Endocarditis in heart valve bioprosthesis caused by Cardiobacterium hominis].

A 36-year-old female patient developed Cardiobacterium hominis endocarditis on a mitral valve prosthesis. The etiologic agent was identified in the seventh day of incubation of the blood cultures specimens. Crystalline penicillin (18.10(6) UI daily) and amikacin (800 mg daily) were administered for 42 days. Surgical treatment for heart failure unresponsive to medical treatment was carried on in the eighteenth day of antibiotic therapy. A bovine pericardium prosthesis was inserted. The patient was discharged and is asymptomatic after seven months.

Adult↗
PubMed1990

Cardiobacterium hominis endocarditis.

A 53-year-old man presented with nonspecific symptoms, evidence of aortic valve regurgitation and hepatosplenomegaly. Blood cultures grew Cardiobacterium hominis after 14 days of incubation. Endocarditis is caused by fastidious organisms such as C hominis in less than 5% of cases. To date approximately 40 cases of endocarditis due to this pleomorphic facultative anaerobic Gram-negative bacillus have been reported. C hominis is part of the normal human mouth flora.

Endocarditis, Bacterial↗
PubMedDate not supplied

Cardiobacterium hominis endocarditis. Report of one case and review of the literature.

We report a case of infective endocarditis due to Cardiobacterium Hominis. This organism has rarely been recognized in the past as a human pathogen on the cardiac valves. This patient escaped early diagnosis, but he was successfully treated with parenteral ampicillin followed by elective aortic and mitral valve replacement. The bacteriological characteristics of this unusual cause of infective endocarditis are discussed and the world literature is reviewed.

Adult↗
PubMed1987

[Cardiobacterium hominis on a aortic valve prosthesis].

A new case of late bacterial endocarditis caused by Cardiobacterium hominis is reported. The infection developed on an aortic valve prosthesis and responded favourably to medical treatment. The main characteristics of the micro-organism and of the oslerian graft are reviewed in the light of published data. The problem of endocarditis with negative blood cultures is discussed since C. hominis is reputed difficult to cultivate, although this was not the case in our patient.

Aortic Valve↗
PubMed1987

Endocarditis due to Cardiobacterium hominis.

A case of subacute bacterial endocarditis was caused by Cardiobacterium hominis in a 55-year-old man who had a history of rheumatic fever. A survey of the literature showed few reports dealing with the isolation of these organisms from human sources. Microbiologically, the chief distinguishing features of C. hominis are its characteristic colonial morphotype, a positive reaction, and its production of indole.

Aortic Valve Insufficiency↗
PubMed1978

Cardiobacterium hominis endocarditis. Four cases with clinical and laboratory observations.

The clinical and microbiologic features of Cardiobacterium hominis endocarditis in four patients seen at the Mayo Clinic from 1971 through 1976 are described. All four were men ranging in age from 39 to 60 years. The precipitating factor in three was a dental procedure, and the illness was a prolonged, chronic one, with symptoms having been present 10 to 18 months before diagnosis. The other patient had a late prosthetic valve endocarditis and had had symptoms for only 3 months. Three patients were cured; the fourth died after 32 days of adequate therapy and what was considered a bacteriologic cure. Because of the pronounced fastidiousness of these bacteria, in vitro susceptibility tests could be done in only two of the four; the minimum inhibitory concentration for penicillin G was 0.07 microgram/ml in both. The therapeutic regimens were penicillin G plus streptomycin in the first case, predominantly penicillin G alone in the second, penicillin G for 2 weeks in the third, and ampicillin for 4 weeks in the fourth (prosthetic valve case) in addition to valve replacement. Clinical and laboratory experiences in the total reported cases lead us to believe that 3 weeks of therapy with penicillin G or ampicillin alone is adequate therapy for C. hominis endocarditis of natural valves.

Adult↗
PubMedDate not supplied

Case report. Cardiobacterium hominis: review of prior infections and report of endocarditis on a fascia lata prosthetic heart valve.

The clinical spectrum of disease caused by Cardiobacterium hominis, a small, gram-negative coccobacillus, is little known to physicians. From analysis of a new case of C hominis endocarditis on a fascia lata aortic valve, and from review of all previous reports of infection due to this microorganism, a remarkably consistent clinical picture emerged. C hominis only causes endocarditis, affects middle-aged individuals with structurally abnormal, left-sided cardiac valves, and follows a subacute course associated with the frequent occurrence of mycotic aneurysms and embolic phenomena. The methodology and therapeutic importance of identifying this organism and separating it from the closely related Actinobacillus actinomycetemcomitans, Eikenella corrodens, and Haemophilus aphrophilus is emphasized. Either penicillin alone or penicillin plus an aminoglycoside is recommended for therapy.

Aortic Valve↗