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Evaluation of fetal intrapartum hypoxia by middle cerebral and umbilical artery Doppler velocimetry with simultaneous cardiotocography and pulse oximetry.

OBJECTIVE: To investigate fetal circulation at different stages of hypoxia during labor, and to study blood flow alterations in the brain and peripheral tissues, through simultaneous use of three non-invasive techniques. MATERIALS AND METHODS: Ninety two pregnant women between 38 and 41 weeks of gestation, comparable for maternal age and parity, were simultaneously monitored with cardiotocography (CTG), continuous fetal pulse oximetry and Doppler ultrasonography during the first stage of labor. In 70 cases evaluation was successful, and useful data was obtained. Doppler waveforms were obtained before and during abnormal CTG patterns, of both the umbilical (UA) and middle cerebral artery (MCA) to measure the pulsatility index (PI), resistance index (RI), and flow velocity integral (FVI). The study population was divided in three groups, according to CTG and fetal pulse oximetry tracings: 20 term fetuses with normal CTG patterns and oxygen saturation (FSPO(2)) values >40%, 30 term fetuses with abnormal CTG patterns and FSPO(2) values between 30 and 40%, and 20 fetuses with abnormal CTG patterns and FSPO(2) values <30% for a time up to 2 min. These were studied and peripartum outcomes were compared. RESULTS: Redistribution of blood flow was noted at FSPO(2) values of 37%, in all groups. In the presence of reduced oxygen saturation (near to or below 30%), MCA Doppler showed significantly lower PI (1.06+/-0.33 vs.0.74+/-0.39, p=0.03) and RI (0.59+/-0.14 vs. 0.44+/-0.14, p=0.03), while that of the UA showed mildly higher resistance indices (0.98+/-0.14 vs. 1.28+/-0.50, p=0.01 and 0.57+/-0.12 vs. 0.79+/-0.24, p=0.004, respectively). When an oxygen saturation value of <30% was maintained for greater than 2 min, MCA Doppler indices reversed, likely indicating morbid fetal hypoxia. Differences in fetal outcomes between groups correlated with Doppler and pulse oximetry tracings. CONCLUSIONS: During active labor the fetus maintains oxygen supply to the brain by redistributing blood flow. In cases of hypoxia this is feasible for only 2 min. We note a strong correlation between fetal pulse oximetry, Doppler velocimetry of the MCA and UA, and fetal morbidity.

Adult↗

Alterations in Doppler velocimetry indices of the umbilical artery during fetal hypoxia in labor, in relation to cardiotocography and fetal pulse oximetry findings.

AIM: The aim was to investigate fetal peripheral blood flow using external cardiotocography (CTG), Doppler velocimetry, and pulse oximetry (PO) in normal labor compared with those complicated by hypoxia. SUBJECTS: During labor, 35 term fetuses with oxygen saturation values (FSPO(2)) between 30 and 40%, and 25 term fetuses with FSPO(2) values < or =30% for a period of 20 s to 2 min were studied. Fetuses were assessed using simultaneous CTG, PO, and Doppler ultrasonography of the umbilical artery (UA). The pulsatility index (PI), resistance index (RI), and flow velocity integral (FVI) were recorded. Peripartum outcomes were compared with those of 30 fetuses with SPO(2) values >40%. All groups presented abnormal CTG patterns and were comparable with regard to maternal age and parity. SETTING: The Fetal Surveillance Unit of the 2nd Department of Obstetrics and Gynecology, "Aretaieion" Hospital, Athens University, Greece. RESULTS: Umbilical artery Doppler revealed an initial increase in the RI and the PI in the presence of decreased oxygen saturation. The differences observed in Doppler velocity and impedance indices correlated with PO values. Fetal outcomes correlated with UA Doppler findings. CONCLUSIONS: Alterations in UA Doppler velocimetry indices were observed during labor-induced fetal hypoxia. PO readings of <40% provoked an increase in the RI and PI. When PO readings remained <30% for >2 min, both the PI and the RI were further increased in a more prominent way. UA velocimetry indices correlated with perinatal outcome.

Adult↗

Effect of methyldopa and isradipine on fetal heart rate pattern assessed by computerized cardiotocography in human pregnancy.

OBJECTIVE: The effects of two antihypertensive drugs, methyldopa and isradipine, on fetal heart rate pattern were analyzed by computerized cardiotocography. STUDY DESIGN: The first part of the study was a prospective, randomized, controlled trial of 19 women with preeclampsia in the third trimester given 2.5 mg of oral slow-release isradipine twice a day or 250 mg of methyldopa three times a day. In a second part of the study 23 women with preeclampsia in the third trimester given 5 mg of oral slow-release isradipine twice a day were compared with 23 matched controls without medication. Main outcome measures were maternal blood pressure and mean baseline fetal heart rate, fetal movements, number of accelerations, periods of high and low baseline variability, and mean baseline heart rate variability. RESULTS: Compared with the pretreatment value, the mean arterial blood pressure decreased significantly in all drug treatment groups. Fetal heart rate characteristics were not significantly changed during drug treatment or bed rest. CONCLUSION: The various features of the fetal heart rate pattern evaluated by computerized methods were not influenced by treatment with methyldopa or isradipine.

Adolescent↗

Randomised trial of cardiotocography alone or with ST waveform analysis for intrapartum monitoring.

It is possible to record the fetal electrocardiographic waveform (ECG) from the scalp electrode used in labour for detection of fetal heart rate. Animal and observational studies of changes in the ST waveform of the ECG during hypoxia suggest that a combination of heart rate and ST waveform analysis might improve the predictive value of intrapartum monitoring. In a randomised trial, we have studied intervention rates and neonatal outcome for high-risk labours monitored either by conventional cardiotocography (CTG) or by ST waveform analysis plus CTG. 1200 women with pregnancy of at least 34 weeks' gestation were assigned to the groups when the decision to apply a fetal scalp electrode was made. Neonatal outcome was assessed by umbilical-cord blood gas analysis, Apgar scores, resuscitation needed, and postnatal course. All recordings were retrospectively viewed by an observer unaware of clinical details to check adherence to the trial protocol. The addition of ST waveform monitoring to CTG substantially reduced the proportion of deliveries for fetal distress (ST + CTG 27/615 vs CTG 58/606; p less than 0.001). The groups did not differ in rate of operative delivery for other reasons, incidence of asphyxia at birth, or neonatal outcome. Metabolic acidosis and low 5 min Apgar scores were less common in the ST + CTG than the CTG group, but not significantly so. The only case of birth asphyxia in the ST + CTG group was identified by both heart rate and ST changes. The review of recordings showed that the reduction in intervention rate was among cases with CTG patterns classified as normal or intermediate, whereas there was no difference in intervention rates among cases with abnormal recordings. Our findings confirm that ST waveform analysis discriminates CTG changes in labour and that our protocol for interpretation is safe. Further randomised studies are warranted.

Adult↗

Antepartum cardiotocography: a study of fetal reactivity in frequency domain.

Cardiotocography (CTG) is the most widely used diagnostic technique in clinical practice to monitor fetal health. Cardiotocographic recording also permits to assess maturation of the fetal autonomous nervous system (ANS): fetal heart rate (FHR) modifications may reveal ANS' reactions to stimuli. To assess fetal reactivity, physicians evaluate specific clinical CTG parameters, generally, by means of visual inspection, thus depending on observer's expertise, with lack of reproducibility. Still nowadays, there is a very high intra- and inter-observer variation in the assessment of FHR patterns. More objective methods for CTG interpretation are of crucial importance. For adults, frequency analysis of heart rate variability (HRV) is a non-invasive and powerful method to investigate ANS activity. This frequency analysis can also be a valid support for a better knowledge of fetal ANS functional state and reactions. Indeed, fetal HRV is a good indicator of fetal well-being in non-stress conditions. Fetal reactivity is a very important CTG characteristic used to diagnose fetal distress, but its interpretation is still uncertain. The aim of this study is to characterise fetal reactivity proposing new fetal HRV frequency parameters to support a more exhaustive CTG analysis.

Cardiotocography↗

Integrated monitoring of fetal growth restriction by computerized cardiotocography and Doppler flow velocimetry.

OBJECTIVE: To investigate the correlations between Doppler flow velocimetry and computerized cardiotocography (cCTG) in fetal growth restriction. STUDY DESIGN: Fifty growth-restricted foetuses with abdominal circumference below the 10th percentile and no major abnormalities were studied. A total of 186 cCTG tracings (at least two per patient) analysed using the HP2CTG system were compared with the corresponding umbilical artery pulsatility index (PI), the PI ratio of umbilical artery to middle cerebral artery, and the ductus venosus systolic/atrial ratio. RESULTS: Worsening in umbilical artery Doppler velocimetry parameters was associated with a significant reduction of short- and long-term variability indices and accelerations. When end-diastolic umbilical artery flow was preserved, a reversed ratio between umbilical artery and middle cerebral artery PIs was not correlated with a worsening of cCTG parameters; in the presence of umbilical artery absent or reversed flow, ductus venosus Doppler velocimetry abnormalities were correlated with a significant reduction of variability. When end-diastolic umbilical artery flow was preserved, there was a progressive increase in variability indices and accelerations with advancing gestational age. In the more compromised fetuses this "maturation" process of cCTG patterns was not found. CONCLUSION: There is a strict correlation between Doppler velocimetry abnormalities and cCTG parameter deterioration, in particular between ductus venosus and variability.

Blood Flow Velocity↗

Computerized cardiotocography in the management of intrauterine growth restriction associated with Doppler velocimetry alterations.

OBJECTIVE: To verify the reliability of computerized cardiotocography (cCTG) in the prediction of the oxygen metabolism status of fetuses with growth restriction and Doppler velocimetry alterations. METHODS: From 24 third-trimester cesarean section performed because of intrauterine growth restriction (IUGR) and Doppler velocimetry alterations, there were 11 cases of fetal heart rate alterations (Dawes-Redman criteria were not satisfied) and 13 cases of reactive cCTG. Fetal lung maturity was detected by amniocentesis and blood samples for umbilical blood gas analysis (UBGA) were collected before the first neonatal breath from the umbilical artery in a double-clamped segment of the cord. RESULTS: Umbilical cord gas analysis showed arterial cord blood pH to be 7.20 or less in 11 newborns (45.8%), 7.10 or less in 6 (25%), and 7.00 or less in 3 (12.5%). Linear regression analysis showed short-term variation (STV) in the fetal heart rate to be significantly correlated with umbilical artery pH (r = 0.49; P = 0.01) and pCO2 (r = -0.50; P = 0.01). There were no significant correlations between cCTG and the other UBGA parameters considered. Receiver operator curves permitted to calculate the STV values at which pathological neonatal UBGA values can be expected (pH < 7.00 and pCO2 > 80 mmHg). A short-term variation less than 4.5 ms was found to predict acidemia with a sensitivity of 100% and a specificity of 70% (positive predictive value, 33%; negative predictive value, 100%), and hypercarbia with a sensitivity of 100% and a specificity of 77.8% (positive predictive value, 55.6%; negative predictive value, 100%). CONCLUSION: In view of the results of this study, 4.5 ms for STV may be a threshold below which timing of delivery should be decided in cases of fetal growth restriction.

Acidosis↗

A simplified form of cardiotocography for antenatal fetal assessment.

Antenatal cardiotocography has become the primary method of evaluation of fetal wellbeing, and the relationship between the presence of fetal heart rate accelerations in response to fetal movement and subsequent good fetal outcome has been demonstrated. However, in areas where electronic monitors are few or not available it would be useful if such accelerations could be demonstrated using the Pinard stethoscope. A prospective study involving 200 women with a singleton pregnancy of more than 34 weeks gestation was performed at Harare Maternity Hospital, Harare, Zimbabwe, when a 6 min electronic trace using an external transducer was compared with simultaneously performed 6 min manual record using the Pinard stethoscope. The findings showed that the manual record has a sensitivity of 75% and although traces with excessive base line variability would show an acceleration on the manual record, in no case with a flat trace was an acceleration noted on the manual record. This acceptable degree of sensitivity would allow for a significant decrease in the number of women being referred for electronic tracing and would be a more appropriate use of limited resources in terms of manpower and equipment.

Auscultation↗

Lactate and acid-base balance at delivery in relation to cardiotocography and T/QRS ratios in the second stage of labour.

OBJECTIVE: To compare foetal electrocardiogram (T/QRS ratio) and cardiotocography (CTG) during the second stage of labour with lactate and acid-base balance in cord artery blood at delivery. DESIGN: Forty-six parturients delivered at the National University of Singapore were monitored during the second stage of labour with T/QRS ratios and CTG. At delivery blood from a segment of clamped cord was sampled for lactate and acid-base balance analyses. The Spearman Rank correlation, the Mann Whitney U-test and the Kruskal Wallis ANOVA were used when appropriate. RESULTS: Maternal pushing time was significantly correlated to lactate (R = 0.51; P = 0.0003), pH (R = -0.38; P = 0.009) and base deficit (R = 0.33; P = 0.026), but not to T/QRS ratio (R = 0.002; P = 0.99). No significant correlation between lactate and T/QRS ratios (R = 0.06; P = 0.70) or type of CTG pattern was found (P = 0.10), though there were significant differences in pH (P = 0.029) and T/QRS ratios (P = 0.037) between groups with different FHR abnormalities. CONCLUSION: Lactate increases progressively with maternal pushing time. No significant correlation was found between lactate and the T/QRS ratio. Lack of correlation is likely to be due to poor sensitivity of foetal ECG at this level of foetal stress, though the influence from transplacentally transferred maternal lactate cannot be excluded.

Acid-Base Equilibrium↗

Fetal cardiotocography and acid-base status during cesarean section.

OBJECTIVE: To assess the fetal well-being during cesarean section, in relation to the previous fetal condition. DESIGN: Observational study. SETTING: University Hospital. PATIENTS PARTICIPANTS: 204 women undergoing cesarean section (203 intrapartum cesarean sections): 177 with general anesthesia and 27 with spinal anesthesia. MATERIAL AND METHODS: We compared the fetal heart records of the last 30 min before cesarean section (during the first stage of labor) with those during cesarean section. Scalp blood analysis 30 min before the beginning of anesthesia induction was compared with umbilical artery analysis at delivery. MAIN OUTCOME MEASURES: Cardiotocography. Acid-base analysis. Apgar scores. RESULTS: During cesarean section there was a reduction in uterine activity, an increase in silent tracings and a decrease in late decelerations. Umbilical artery pH was lower than scalp pH (7.23+/-0.06 vs 7.30+/-0.06). Oxygen saturation was also lower (14.43+/-8.58% vs 18.99+/-8.4%). The values of pCO2 and of base deficit were higher. During cesarean section low values of modified Fischer scores were associated with low pH values of umbilical artery and low Apgar scores. CONCLUSION: Silent tracings appearing during cesarean section usually do not indicate fetal distress. Poor intracesarean fetal heart tracings were associated with worse indicators of neonatal well-being. Although umbilical pH were lower than scalp values, when the correction described in the literature was applied, the difference was of little clinical relevance. It is concluded that anesthesic, pharmacological and surgical events have slight repercussion in fetal well being. However, in a few cases fetal heart monitoring during cesarean section could detect otherwise undiagnosed cases of transient acidemia or depression in the fetus.

Acid-Base Equilibrium↗

[Fetal monitoring intra partum with cardiotocography and fetal blood sampling analysis and its possible influence on the C-section rate].

In times of rising c-section rates worldwide the obstetricians feel a big responsibility in avoiding a secondary c-section for non-reassuring fetal heart rate. No other experimental method has been established beside the gold standard (cardiotocography and fetal blood sampling) in daily routine until today. The two cases presented demonstrate the fallibility of the "gold standard" in predicting fetal asphyxia and why methodology with better positive predictive value is needed.

Adult↗

[Quantitative Cardiotocography--what does it look like and what can we expect].

BACKGROUND: [corrected] Cardiotocography (CTG) seems to be a non-reliable, expensive but nevertheless practical method for fetal surveillance. Moreover, its diagnostic value is dependent on a long-standing experience of the obstetrician (midwife). It is difficult to define exact diagnostic criteria since nearly all CTG phenomena are lacking precise qualification by the naked eye. Therefore, the idea must be born in mind to analyze fetal heart frequency (FHF) by computer, first off-line then on-line, in order to evaluate its true diagnostic power objectively. METHODS: The FHF of 583 deliveries terminated by the vaginal route were registered prospectively using a PC and an RS422 interface. In 443 cases acid-base measurements (ABL 500, RADIOMETER, Copenhagen) in blood of the umbilical artery (UA) and vein (UV) were available and plausible. In this study only the last 30 min ante-partum were analyzed. The program for FHF analysis was written in MATLAB (The Mathworks Inc., USA). A CTG score was developed using three components of FHF: basal FHF, the deceleration area of all dips, and the micro-fluctuation (MF) of the basal fetal heart rate (FHR). MF denotes the true number of "turning-points" per minute of basal FHR. For each component a maximum of 6 scoring points could be assigned according to empirical cut-off values. These cut-off values were determined using correlation analysis with acid-base parameters in UA blood, especially the actual pH. The accordance between score and pH values was further demonstrated by assignment of 0.036 pH-units to each of the 19 (18 + zero) scoring points, thus covering a pH range between 6.700 and 7.350 (UA). A resulting variable, delta pH (pH measured, UA-pH assigned) was studied and used for further analysis. In order to define criteria for fetal mortality in utero only cases with pH, UA between 7.250 and 7.350 were accepted. RESULTS: Median basal FHF under normal conditions amounted to 138 bpm (mean: 137 +/- 14.9) in 4180 minutes of 372 fetuses. 120 bpm equals the 13.4(th) and 160 bpm the 94.6(th) centile of the distribution. Given fetal normacidity (UA) MF is 58/minute and the mean MF 57.9 +/- 13.4, respectively, with a 10 (th) centile of 41/minute. MF and basal FHF are correlated significantly (r = 0.410, P << 10(-4)). The declaration-area per fetus is significantly correlated with actual pH (UA), r = -0.473, P << 10(-4). the score itself is highly significantly correlated with actual pH (UA) (r = -0.559, P << 10(-4)) and the other parameters of fetal acid-base balance. Nevertheless, prediction variability for pH, especially in score = 1, 2 and zero (minimal CTG pathology) is still present: 80% of all predicted pH values lie in between -0.092 and + 0.071. It is strongly suggested that this score-related predictive pH variability is caused by maternal breathing habits during the last 30 minutes of delivery. CONCLUSION: Adequate quantification of only three variables of FHR using a score leads to fairly good correlations with parameters of the fetal acid-base balance. Thus actual pH (UA) can be predicted in reasonable clinical limits. Still present variability in prediction of pH seems to be, in part, of maternal origin. The maternal influence could be eliminated by continuous (transcutaneous) monitoring of maternal pCO(2). Along these lines the quantitative electronic monitoring of FHR will be realized and instrumented (off-line and on-line) by nexus/gmt, Frankfurt, a.M., Germany.

Acidosis↗

The combination of computerized cardiotocography and amniotic fluid index for the prediction of neonatal acidemia at birth: a modified biophysical profile.

OBJECTIVE: To study the combination of computerized cardiotocography (cCTG) and the amniotic fluid index (AFI) in the prediction of neonatal acidemia at birth. METHODS: A total of 89 singleton third-trimester high-risk pregnancies delivered by Cesarean section, with an AFI evaluated within 24 h from birth, and an antepartum cCTG performed within 6 h from delivery, were studied. The score was the sum of values for AFI (oligo/anhydramnios = 1, normal = 0) and cCTG (Dawes-Redman criteria, not met = 1, met = 0). The endpoint was to predict an abnormal neonatal outcome as defined by an umbilical artery pH of < or = 7.2. RESULTS: Fifteen neonates had an umbilical artery pH of < 7.2. The combination of cCTG + AFI score was able to predict pH values (< or = 7.20) with an OR = 2.83 (p < 0.02). The diagnostic accuracy of the combination of cCTG + AFI was as follows: sensitivity 80%, specificity 58%, positive predictive value 28%, negative predictive value 83%. COMMENT: We suggest that the cCTG + AFI score may be of value in the prediction of neonatal acidemia and help in the management of third-trimester high-risk pregnancies.

Acidosis↗

Can antepartum computerized cardiotocography predict the evolution of intrapartum acid-base status in normal fetuses?

BACKGROUND: To study the relationship between antepartum computerized cardiotocography (cCTG) and the evolution of intrapartum fetal acid-base balance in a low-risk population. METHODS: Forty-nine healthy fetuses were prospectively followed up by antepartum cCTG (Oxford System 8002), fetal scalp blood sampling at the onset of the active phase of dilatation (3 cm) and at the beginning of the second stage of labor (10 cm) and study of acid-base status at birth in the umbilical cord. Correlation studies and linear regression analysis were performed. RESULTS: Normal prelabor cCTG was followed by normal fetal acid-base balance in the different study periods. No relationship was found between cCTG parameters and the absolute values of fetal acid-base status. However, the more favorable the antepartum cCTG parameters were, the more favorable the fetal acid-base evolution during the active phase of dilatation was. In contrast, no significant correlations were found between antepartum cCTG and fetal acid-base changes during the second stage of labor. CONCLUSIONS: In normal fetuses, a single antepartum cCTG identified correctly fetal well-being during labor and at birth and was able to predict fetal acid-base evolution during the active phase of dilatation. However, fetal biochemical changes during the second stage could not be predicted by any antepartum cCTG parameter.

Acid-Base Equilibrium↗

Fetal pulse oximetry and wavelet analysis of the fetal heart rate in the evaluation of abnormal cardiotocography tracings.

AIM: Previous studies indicate that the addition of wavelet analysis of the fetal pulse oximetry tracings (FSPO2) and fetal heart rate (FHR) variability to cardiotocography (CTG), for intrapartum fetal monitoring, provides useful information on the fetal response to hypoxia. We applied the new procedure in non-reassuring CTG patterns, in which cesarean section was performed, and tested its accuracy in the diagnosis of the intrapartum fetal compromise. METHODS: At the 'Aretaieion' University Hospital labor ward, 318 women with term fetuses in the cephalic presentation entered the trial during labor. They all were monitored with external CTG and fetal pulse oximetry. In the cases that cesarean section was applied, because of abnormal CTG tracings, we applied a method based on the multiresolution wavelet analysis and a self-organized map neural network on the first and second stage of labor. The main outcome parameter was the rate of cord metabolic acidosis at birth (pH < 7.05). Secondary outcomes included Apgar scores at 5 min, fetal transmission to neonatal intensive care unit (NICU) and neonatal encephalopathy. RESULTS: Fifty out of 318 cases delivered operatively because of abnormal CTG patterns (rate 15.72%). In 30 cases, cord pH was >7.05, while in 11 Apgar scores at 5 min were <7, while none of those neonates were transferred to NICU. In the rest 20 cases cord pH was <7.05; in all of these cases Apgar scores at 5 min were <7, while four neonates were transferred to NICU. In one of them, neonatal encephalopathy was diagnosed. After the offline application of wavelet analysis and neural networks to the pulse oximetry and FHR variability readings of the 50 cases, statistics calculated that the system showed a sensitivity of 85% and a specificity of 93%, while false negative and false positive rates were 15% and 7%, respectively. CONCLUSION: Computerized FHR and FSPO2 monitoring shows an excellent efficacy and reliability in interpreting non-reassuring FHR recordings.

Apgar Score↗

Clinical overview of cardiotocography.

Twenty years after its widespread introduction, the role of continuous fetal heart rate and contraction monitoring in labour (cardiotocography, CTG) remains uncertain. Although a normal pattern is very reassuring about fetal condition, the predictive value of an abnormal pattern is low. In most studies the use of CTG has been associated with an increase in intervention in labour, particularly caesarean section, without clear evidence of benefit. Fetal blood sampling is the most useful associated technique for minimizing unnecessary intervention. The relationship between fetal heart rate, fetal blood pH changes and long-term outcome remains obscure and further work to clarify this relationship is urgently needed.

Cardiotocography↗

A comparison of intrapartum automated fetal electrocardiography and conventional cardiotocography--a randomised controlled study.

OBJECTIVE: To examine whether intrapartum monitoring by means of automatic ST analysis (STAN) of fetal electrocardiography could reduce the rate of neonatal acidemia and the rate of operative intervention during labour, compared with monitoring by means of cardiotocography (CTG). DESIGN: Randomised controlled trial. SETTING: Labour ward in tertiary-level university hospital. SAMPLE: A total of 1483 women in active labour with singleton term fetus in cephalic presentation. METHODS: Women were randomly assigned to be monitored either by STAN or by CTG. Fetal blood sampling (FBS) was optional in both groups. MAIN OUTCOME MEASURES: Neonatal acidemia (umbilical artery pH <7.10), neonatal metabolic acidosis (umbilical artery pH <7.05 and base excess <-12 mmol/l) and operative interventions: caesarean section rate, vacuum outlet (VO) rate and FBS rate. RESULTS: There were no statistically significant differences between the STAN group and CTG group in the incidence of neonatal acidemia (5.8 versus 4.7%) or metabolic acidosis (1.7 versus 0.7%). The caesarean section rate (6.4 versus 4.7%) and the VO rate (9.5 versus 10.7%) were also similar in the STAN and CTG groups. The incidence of FBS was lower (P < 0.001) in the STAN group (7.0%) than in the CTG group (15.6%). CONCLUSIONS: Intrapartum fetal monitoring by means of automatic STAN did not improve the neonatal outcome or decrease the caesarean section rate. However, the need for FBS during labour was lower in the STAN group.

Acidosis↗