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Four commonly used methods for evaluating depth of cure in light-activated composites were compared. Optical and scraping methods correlate well, but severely overestimate depth of cure as compared with hardness testing or degree of conversion analysis. Degree of conversion appears to be the most sensitive test of depth of cure.
We examine critically the two traditions of work that have informed discursive approaches to identity: social constructionism and conversation analysis. Within both strands, identity is theorized as a flexible phenomenon that is situated in conversations. But although constructionists locate identity within the social, such work remains at a theoretical and rather abstract level and often fails to interrogate the discursive practices through which identity is constituted. Conversely, this attention to the occasioning of identity in everyday talk is precisely the focus of the second, conversation analytic strand of work. Whereas constructionists attend to the wider cultural positioning of identities, conversation analysts resist commenting upon the social significance of what is constructed in interaction. Conversation analysis is therefore limited by its restricted notion of culture in the study of the situated social self. Despite the apparent conflict between these approaches, we suggest that a synthesis of the two provides a comprehensive framework for analysing identity. Drawing upon the BBC Panorama interview between Martin Bashir and Princess Diana, we explore how culturally situated identities are located in this conversational context. We conclude that analysts must not only attend to the micro-level organization of identities but also engage in a wider understanding of the cultural framework within which they are located.
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AIM(S) OF THE STUDY: This study explores the relationship between informal carers of older people, and health care workers within the context of a hospital ward. Through an analysis of their language-based encounters the purpose of the study was to identify the discursive processes involved in face-to-face informal carer-health care worker interactions, during the course of carers' visits to one elderly care rehabilitation hospital ward. DESIGN: An ethnomethodological research design, which encompassed the concerns of conversation analysis and the study of institutional interaction, was used. The study involved videotape recording informal carers naturally occurring spontaneous interactions with a range of health care workers on the ward. Data collection was carried out for between 1 and 3 hours, two to three times a week over a period of 3 months. The data comprised: 30 dyadic and group interactions involving 19 different carers and 25 different health care workers, including nurses (qualified and unqualified), physiotherapists, occupational therapists, dieticians, ambulance personnel, housekeepers and nursing auxiliaries. Detailed transcriptions of the data were produced and analysis was undertaken using a modified conversation analysis approach. FINDINGS: Analysis revealed that a central aspect of the way the relationship between informal carers and health care workers is framed is by the way information and access to information is obtained. This paper examines some of the aspects of informal carer-health care worker discourse, which denote both parties as gatekeepers. In doing so it considers the roles that legitimatization of competence and knowledgeability have in facilitating informal carers interactions with health care workers. CONCLUSIONS: We conclude that the accomplishment of legitimacy is largely a collaborative undertaking on behalf of health care workers and informal carers. The implications of these findings for carers, health care workers, policy and future research are discussed.
This paper explores the verbal and non-verbal communication between nurses and post-anaesthetic patients in the recovery unit of an inner London hospital. Although the patients had only minor operations the study findings and the method of conversation analysis provide ideas which could have wider relevance in intensive care. A video camera was used to record nurses' conversations with dental patients recovering from their operations. The resultant tape was studied for the utterances and body movement used by the nurses in order to engage the patient in conversation. Analysis indicated that the nurses were skilled communicators who took into account the patients' low level of consciousness and lack of physical orientation when initiating and maintaining interaction. This is an important factor in the care of post-anaesthetic patients, as the recovery nurse may need to gain the patient's attention to converse with him for a variety of reasons, including safety and the need to orientate the patient to his environment in order to reduce anxiety (Mallett, 1986). The ability of the nurse to communicate successfully is, therefore, one of the prerequisites for adequate nursing care in the Recovery Unit. In addition, the notion of therapeutic communication as a separate entity to skillful conversation is raised.
This study investigated the impact of right cerebral hemisphere damage on the capacity to take shared responsibility for the development of an intentional structure in conversation. Intentions are important determiners of both discourse structure and utterance meaning in context. Right-hemisphere damaged (RHD) individuals have been reported to have difficulty in the use of prosody as well as performing and appreciating the process of discourse tailoring which is dependent on recognizing speakers intentions. Audio taped samples of naturalistic conversations between RHD individuals and normal speakers were analysed. Text-level discourse processing analyses involved measures of global discourse structure and self-monitoring accuracy. Prosodic analyses included fundamental frequency (F0) resetting, pause durations and inter-turn intervals. The results revealed that speakers with right cerebral hemisphere damage do not, first, use prosody to alert listeners to changes in discourse structure, and, second, assume equal responsibility for the development and maintenance discourse structure.
In cross B163, heteroallelic am1 am6 and heterozygous for both conventional genetic flanking markers and closer molecular markers, we previously found that the majority on flanker exchanges were remote from events that generated prototrophic recombinants. We report here that natural polymorphisms distinguishing the parents of cross B163 also include sequences within and closely flanking am. Segregation of these markers in B163 prototrophs confirms that the majority of meiotic recombination events at am resulted from gene conversion. Conversion of am6, the distal allele, is more frequent than conversion of am1. Twelve percent of tracts in am6 convertants were discontinuous while 30% of continuous tracts converting am6 extend less than 741 bp.
The demand for explicitness in the way health visitors target their services has given rise to a plethora of different health needs assessment tools (HNATs). This paper describes an in-depth conversational analysis of the use in practice of these structured health needs assessment tools (HNATs) in two different NHS Community Trusts in England. These HNATs aimed to enable clients to participate in the assessment of their own health needs, as well as fulfilling the political requirements of justifying the expenditure of health visitor time where needs are identified. However, conversational analysis of 10 interactions showed that use of the instruments was associated with a failure to either identify needs that are relevant to the client or to enable clients to participate in the process. Use of the structured instrument simultaneously emphasises the significance of a professional lead, instead of client participation, and minimises the importance of inter-personal relationships and communication. In one site, a directly controlling style was apparent in the practice of health visitors who were, themselves, explicitly controlled by their managers. In the other site, professional expertise was emphasised, and a covert assessment style acted to disempower clients. The controlling nature of the interactions, the number of missed cues and the possibility of distress caused by the insensitivity of questioning style are all potentially harmful side effects of using structured instruments to assess needs. The problems seem to stem from the use of a pre-determined list of questions that form the basis for assuming that any family's health promotion needs can be categorised and predicted in advance. In conclusion, therefore, it is recommended that health visitors should use the open, conversational style of needs assessment that has been shown to be effective and acceptable, rather than an approach based on a structured instrument.
At the ade6 locus of Schizosaccharomyces pombe flanking markers have been introduced as well as five silent restriction site polymorphisms: four in the 5' upstream region and one in the middle of the gene. The mutations ade6-706, ade6-M26 (both at the 5' end) and ade6-51 (middle of the gene) were used as partners for crosses with the 3' mutation ade6-469. From these three types of crosses, wild-type recombinants were selected and analyzed genetically to assess association with crossing-over and physically to determine conversion tract lengths. The introduced restriction site polymorphisms (five vs. only one) neither influenced the pattern of recombinant types nor the distribution of conversion tracts. The hotspot mutation M26 enhances crossing-over and conversion to the same proportion. M26 not only stimulates conversion at the 5' end, but does this also (to a lower extent) at the 3' end of ade6 at a distance of more than 1 kb. The majority of meiotic conversion tracts are continuous and postmeiotic segregation of polymorphic sites is rare. Conversion tracts are slightly shorter with M26 in comparison with its control 706. The mean minimal length of tracts varies from 670 bp (M26) to 890 bp (706) to 1290 bp (51). It is concluded that M26 acts as an initiation site of recombination or enhances initiation of recombination. M26 does not act by termination of conversion. A region of recombination initiation exists at the 5' end of the ade6 gene also in the absence of the ade6-M26 hotspot mutation.
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The experience of conversing with a person who has autism is often described as unsatisfactory. This article offers some suggestions as to why that might be. Conversation between an adult diagnosed as autistic and a researcher was transcribed and analyzed using the methodology of Conversation Analysis. The analysis highlights differences in conversational style between the two participants based on features such as topic movement, topic maintenance, repairs, interference from earlier structures and common collocations, overlaps, latching, and pauses. It is suggested that many of the features of the subject's talk which result in an overly repetitive style may be cognitively motivated.
One of the major inconveniences encountered in sleep studies is the time consuming labor involved in equating visual analysis of physiological recordings (EEG, EMG, EOG, ...) to an appropriate state of vigilance. The explosion of computer technology is responsible for the emergence of several automated sleep-wake staging systems to supplement human analysis. Conversely to human sleep analysis, rat sleep is characterized by the absence of consensus about numerous elements constituting the sleep-wake staging systems used to build a hypnogram (recording position, length of epoch, number and definition of the vigilance state discriminated, ...). If justified, the choices of the parameters involved by each system generally result from various viewpoints (physiology, mathematics, electronics, ...). The diversity generated by the liberty offered the investigator in building a system excludes any rigorous comparison between systems. Nevertheless, this variety can also be viewed as a representative of the effervescence of research in the field of sleep, and as a catalyst for new ideas.
We investigated speaking fundamental frequency and periodicity of voicing during conversational speech in a 105-year-old woman. Analyses revealed higher mean speaking fundamental frequency compared to previously published data obtained from elderly women. In the absence of normative data, the results of cepstrum analyses performed on vowels produced during connected speech revealed less periodicity for the 105-year-old woman's voice than for a 35-year-old woman's voice. The main finding of this study indicates that previously reported group trends regarding aging effects on mean speaking fundamental frequency of the female voice cannot simply be attributed to all elderly individuals. These results stress the importance, for clinical and research purposes, of recognizing the existence of considerable intra- as well as intersubject variability in the effects of aging on the voice.
A general statistical test of the stability of measurement conditions was demonstrated on the beta-spectra of 241Pu cumulated during four years. The alpha- and gamma-ray spectroscopy indicated stability of the 241Pu source. Monte Carlo modelling of individual collision events clarified the role of electron scattering and energy losses within a radioactive source down to energies of several hundreds of eV. The impact ionization by beta-particles of carbon and oxygen atoms in a surface contamination layer on the 241Pu and 63Ni sources was observed.
The paper compares Bales' Interaction Process Analysis (IPA) with Sacks' Conversation Analysis (CA), arguing that CA has answered several questions that originally motivated the development of IPA, and while doing so, it has re-specified the phenomena of interaction research. These two research traditions are in many ways diametrically opposed: the former is quantitative, theory-oriented and aims at global characterizations of interactional situations, while the latter is qualitative, inductive and aims at characterizing specific layers of organization (such as turn taking or sequence organization) that give structure to interactional situations. Their primary objects of study are different. For the Balesian tradition, it is the functioning and the structure of a small group, whereas in the Sacksian tradition, it is the structures and practices of human social interaction per se. It is argued, however, that CA has radically expanded understanding of the questions IPA was originally developed to address. These questions include allocation of resources, control and solidarity. Bales' research deals with them in terms of the differentiation of participants of a group, whereas CA has re-specified them as emergent aspects of the very rules and structures that constitute and regulate interaction sequences. The uniqueness of the CA perspective on social interaction is demonstrated by exploring the display of emotion as an interactional phenomenon. It is argued that the display of emotion is intrinsically embedded in the sequential organization of action. Sensitive 'coding and counting' approaches can detect emotion displays, but the contribution of CA is to show the specific ways in which they are part of the business of interaction.
The formation of low-density lipophorin (LDLp) in insect hemolymph, resulting from association of high-density lipophorin (HDLp) with both lipid and apolipophorin III, is considered to provide a reutilizable lipid shuttle for flight muscle energy supply. The changes in lipid and apolipoprotein composition of LDLp, isolated after flight activity, compared to that of HDLp in the hemolymph at rest, were studied in two evolutionary divergent insects, the hawkmoth Acherontia atropos and the migratory locust, Locusta migratoria. Using FPLC on Superose 6 prep grade as a novel technique to separate the apolipophorins of HDLp and LDLp, the ratio of apolipoprotein I, II, and III in HDLp of both species was demonstrated to be 1:1:1, whereas flight activity resulted in a ratio of 1:1:10 in LDLp. Injection of adipokinetic hormone into resting moths showed that, depending on the dose, the number of apolipophorin III molecules in LDLp can exceed that recovered after the physiological condition of flight. Analysis of the lipophorin lipids demonstrated that in addition to the considerable increase in diacylglycerol in the LDLp particle, which is consistent with the role LDLp in energy supply, particularly the hydrocarbons were increased compared to HDLp, rendering the mechanism of LDLp formation from HDLp even more complex.
Methodology was evolved for comparison of methylprednisolone disposition in man and rabbit. Methylprednisolone, methylprednisone, and methylprednisolone hemisuccinate ester concentrations in plasma were measured by HPLC methodology after iv administration of each compound to rabbits. Methylprednisolone hemisuccinate is rapidly and completely hydrolyzed to methylprednisolone with a half-life of 10 min. Dosing with the free alcohol or ester produces identical disposition curves for methylprednisolone. Methylprednisolone was found to undergo rapid and reversible metabolism with methylprednisone, a phenomenon also seen in man. Plasma concentrations of methylprednisolone are appreciably greater than the metabolite regardless of the form of steroid given. Administration of the metabolite yields 67% availability of methylprednisolone. The occurrence of reversible metabolism produces an apparent clearance which is about 71% of the value of the "real" elimination clearance for both steroids. Man and rabbit show identical plasma protein binding of methylprednisolone (77%). Small differences in apparent clearance (man, 5.74 ml/min/kg; rabbit, 7.93 ml/min/kg) can be accounted for by the animal scale-up principle (body weight0.89). The rabbit is thus a useful animal model for further assessing mechanisms of drug- or disease-steroid interactions which occur in man.
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