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Results for “Decompression, Surgical”

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At least 55 records · Page 3Linked to original sources
PubMed1999

Surgical decompression of ductal obstruction in patients with chronic pancreatitis.

BACKGROUND: Recurrent acute pancreatitis often leads to chronic obstructive ductal disease requiring operative decompression. METHODS: From 1983 through 1998, 124 patients with ductal obstruction underwent lateral pancreaticojejunostomy (78 patients), distal pancreatectomy with end-to-side pancreaticojejunostomy (27 patients), distal pancreatectomy with placement of a pancreas with a filleted duct within a jejunal limb (15 patients), or pancreaticoduodenectomy (4 patients). Preoperative symptoms included abdominal and back pain (99%), nausea with vomiting (99%), and diarrhea with weight loss (11%). Associated conditions included hypertension (20%) and diabetes mellitus (12%). Endoscopy in 106 patients demonstrated distal stricture (37%), proximal stricture (36%), pseudocyst (30%), chain of lakes (15%), calcification and debris (19%), and bile duct stricture (8%). RESULTS: Two patients died, one of an unrecognized esophageal perforation during intubation and the other of leakage of a 1-layer pancreaticojejunostomy. Thirty-six patients developed 53 complications including intra-abdominal abscess (7 patients) and bleeding requiring reoperation in 1 patient. Pain relief was complete in 61 patients, substantial in 39 patients, moderate in 11 patients, minimal in 8 patients, and nonexistent in 3 patients with multiple stones and narrow duct. Ten patients died, with 6 deaths as a result of pancreatic cancer Two other patients may have died of pancreatic cancer. CONCLUSIONS: Lateral pancreaticojejunostomy is the procedure of choice in most patients. Recurrent pancreatitis usually follows alcoholic binges. Long-term follow-up must assess for pancreatic cancer.

Adult↗
PubMed2003

[The effects of hyperbaric oxygen and surgical decompression in experimental compartment syndrome].

BACKGROUND: To determine the beneficial effects of adjuvant hyperbaric oxygen therapy (HBO) in an experimental compartment syndrome model. METHODS: Twenty Wistar albino male rats, weighing between 270-325 g. were divided into four groups as: Control, Fasciotomy, HBO and HBO-Fasciotomy. Rear legs of all animals were strangulated with a tourniquet for 4 hours. Fasciotomy was performed by double incisions. HBO protocol was set as: 6 sessions/day in the first two days, 4 sessions/day in the 3rd and 4th days. The intra-compartmental pressure and leg volume in all groups were measured daily. The legs of the sacrificed animals underwent histopathological examination. RESULTS: Fasciotomy was more effective than HBO to decrease leg volume and intra-compartmental pressure. The combination of HBO and fasciotomy was more effective than the single application of HBO and fasciotomy. The findings of inflammation and necrosis were less in the HBO group when compared with the fasciotomy and HBO-fasciotomy groups. This result was attributed to the higher risk of infection and mechanical damage in the groups with fasciotomy. CONCLUSION: Adjuvant HBO is beneficial in the treatment of compartment syndrome.

Animals↗
PubMed2003

[Surgical decompression in space-occupying cerebral infarct; notification of a randomized trial].

Patients with a hemispheric infarct and massive space-occupying brain oedema have a poor prognosis. Despite intensive conservative treatment, the case fatality rate may be as high as 80%, and most survivors are left severely disabled. Non-randomised studies suggest that decompressive surgery substantially reduces mortality and improves the functional outcome of survivors. The 'Hemicraniectomy after middle cerebral artery infarction with life-threatening edema trial' (HAMLET) is a newly-conceived randomised multi-centre clinical trial that compares the efficacy of decompressive surgery to improve functional outcome with that of conservative treatment in patients with space-occupying supratentorial infarction.

Brain↗