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At least 55 records · Page 3Linked to original sources
PubMed1978

[Patterns in the development of radiation tumors of the stomach and intestines].

In the experiments on dogs and rats it was shown that gastric and intestinal neoplasms arise under the influence of different kinds of radiation, these may be located in all portions of the stomach and bowel and are of a different histological origin. They are not infrequently primary multiple, mostly benign neoplasms which show multicentric growth. The frequency of tumors appearance, their localization, an average latent period, the degree of malignancy and multiplicity are conditioned by the amount of tissue dosage, the topography of their distribution in the alimentary tract and the level of total irradiation of the organism. With the increased dosage of local irradiation the latent period and multiplicity are decreased, while the incidence of malignancy raised. The optimum levels of the tissue dosage and the time of maximum tumor appearance were determined for each type of radiation.

Alpha Particles↗
PubMed1990

Radiobiology of pions in comparison with other heavy particles.

Our recent data on late effects of pions in spinal cord, lung and rectum in rodents is presented with reference to other high-LET radiations. Unlike high-LET radiations such as neutrons and neon ions, the RBE for late effects of pions (up to 1.5) is not found to be significantly different from acute effects. Because of the potential of matching treatment volume (especially by using dynamic treatments) to the target volume by using pions and heavy ions, it is of utmost importance to study the tolerance of normal tissues to late effects as a function of volume. Such knowledge combined with pion and heavy ion dynamic treatment could lead to a further step in heavy particle radiotherapy.

Animals↗