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At least 55 records · Page 3Linked to original sources

Didactic review of 175 radionuclide-guided excisions of osteoid osteomas.

The complete removal of a lesion which resembles, or is covered by adjacent tissue may be difficult. Therefore, the capacity of certain lesions to specifically concentrate a radiopharmaceutical has been used to orient progress during surgery. Usually, the measurements of radioactivity in the operative field are carried out by means of small, handy radiation-detecting probes which can be sterilized. "Intra-operative nuclear medicine" or "radionuclide-guided surgery" has steadily gained in importance. However, this technique is not being taught. Our study, based on radionuclide-guided surgery of 175 orthopaedic patients suspected of having osteoid osteoma, is well suited to teach the particularities of intra-operative radiation detection, as well as the collaboration between the nuclear physician and the surgeon in the operating theatre.

Adult↗

Case report 679. Central low-grade osteosarcoma with foci of dedifferentiation.

An infrequently encountered case of well-differentiated CLOS containing dedifferentiated tumor foci in a 28-year-old Japanese man is reported. The patient died from widespread metastases with a microscopic appearance identical to the anaplastic dedifferentiated lesions of the original tumor. This is, to our knowledge, the first report of a case of CLOS with dedifferentiation at the time of initial surgery. The literature concerning CLOS was reviewed and the diagnostic features of CLOS discussed.

Adult↗

Giant cell tumor of bone.

Giant cell tumor of bone is an enigmatic osseous neoplasm that is histologically benign but clinically shows local aggression and metastatic potential. The absence of clinical, radiographic, or pathologic features that are predictive of tumor behavior and patient outcome has resulted in recent attention to the pathobiology of giant cell tumor of bone. In this report, the clinicopathologic features of and current treatment approaches to giant cell tumor of bone are reviewed. Recent investigations of the specific role of the cell populations present in giant cell tumor of bone that influence tumor proliferation, bone resorption, and its clinical behavior are described.

Angiogenesis Inhibitors↗

Diagnosis of osteoid osteoma using computed tomography.

Osteoid osteoma is a benign lesion of bone generally diagnosed using conventional radiography or conventional tomography. Computed tomography can be used in difficult cases to localize a clinically suspected lesion. In this report we present two patients in whom an osteoid osteoma was detected using computed tomographic scanning; in an additional patient computed tomography failed to localize a lesion, probably because the slice thickness was too great. Because the nidus of the lesion is small--generally several millimeters in diameter--accurate CT localization requires that narrowly collimated, closely spaced sections be obtained.

Adolescent↗

Chest wall repair with a titanium instrument.

We performed chest wall repair with titanium alloy instruments as artificial ribs for prevention of paradoxical respiration and protection of the lung and liver after chest wall resection including the nearly entire length of the right seventh to the eleventh ribs and the costal arch for metastasis of osteosarcoma. The technique of this operation is presented diagrammatically.

Adolescent↗

Palatine tonsillar metastasis from carcinoma of the colon.

Metastatic carcinoma of the palatine tonsil is rare, with only 92 cases reported in the world literature. We report a case of tonsillar metastasis from the colon. This is an unusual case not only because it is the first case report of tonsillar metastasis from this site but also because the tonsillar secondary is the first sign of the primary disease.

Adenocarcinoma↗

Acute arthritis as an unusual complication of malignancy.

A 59-year-old man presented with an inability to weight-bear due to an acute, red, hot, swollen knee joint which was subsequently found to be due to a malignant joint effusion consequent to colonic carcinoma. Treatment with radiation therapy relieved his symptoms. A review of the literature reveals that malignant joint effusion is rare and this is only the third reported case secondary to colonic carcinoma.

Acute Disease↗

[An extended CT scale technique for evaluating periprosthetic bone lesions - an in vitro study].

PURPOSE: In the present study the reduction of artifacts using an extended CT scale technique was examined in 5 vitallium and 5 titanium-aluminium-vanadium tumor prostheses. METHODS: 5 titanium-aluminium-vanadium and 5 vitallium distal femur Mutars(R) tumor prostheses (Mutars(R) - Modular Universal Tumor And Revision System) were implanted in 10 human femur specimens. 110 artifical drill hole lesions of 1 mm, 2 mm, 3 mm, 5 mm and 8 mm diameter were placed in the bone around the hexagonal stem of the tumor prosthesis and furthermore in the proximal part of the femur. All specimens were examined using conventional CT and an extended CT scale technique in a slice thickness of 3 mm. RESULTS: In the proximal part of the femur all drill holes could be detected using 3 mm slices, no artefacts were observed. Along the hexagonal stem smooth lines arising from each hexagonal plane could be observed. This made it impossible to detect a 1 mm drill in 1 vitallium and in 1 titanium-aluminium-vanadium stem. There was no difference between the extended CT scale and conventional CT. CONCLUSION: The extended CT scale did not significantly (p > 0.05, t-test) improve the imaging of artificial drill hole lesions along the hexagonal Mutras(R) stem.

Aged↗

[Tumor-like bone lesions in sternocostoclavicular hyperostosis and palmoplantaris pustulosis].

We present two unusual cases of sternocostoclavicular hyperostosis (SCCH) in conjunction with palmoplantar pustulosis (PPP) and additional tumour like manifestations in a scapula and a femur respectively. The association of SCCH with complexes of signs and symptoms such as chronic multifocal osteomyelitis (CRMO), or other nosological entities such as seronegative spondylarthropathies, is discussed.

Adult↗

Bone scintigraphy of osteoid osteoma: a clinical review.

Osteoid osteoma is a painful osteoblastic process. The pre-operative diagnosis is usually made by roentgenogram. Four surgically confirmed cases are examined where the preoperative diagnosis was clarified by bone scintigraphy. The clinical indications, the diseases process, the literature are reviewed.

Adolescent↗

Three-phase skeletal scintigraphy for suspected bone tumors.

The advantage of using three-phase skeletal scintigraphy rather than merely conventional delayed imaging in the investigation of suspected bone tumors is illustrated by two cases in which this procedure provided greater information on the site and extent of the lesion than other single modalities.

Adolescent↗