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[Chronic fetomaternal transfusion].

Transplacental feto-maternal hemorrhage was diagnosed after delivery of a highly anemic infant from a healthy mother with polyhydramnios by demonstration of fetal red cells in the maternal circulation (145 degrees/00) using a modified Kleihauer technique. Other causes for anemia such as hemolysis, coagulopathies, failure of red cell production or perinatal posttraumatic bleeding were excluded. The transfused volume estimated eexceeded the blood volume of the newborn by several times, thus indicating a chronic blood loss. This was confirmed by hematologic data typical for a normovolemic anemia, a low serum iron level and the development of a congestive heart failure in the newborn infant.

Adult↗

[Fetomaternal transfusion in relation to mode of delivery. Comparison of data from the DFG multicenter study "Rhesus negative" (1965-70) with data from the Freiburg University Gynecologic Clinic (1989)].

Fetomaternal hemorrhage with transfusion of more than 10-25 ml fetal blood into the maternal circulation ("macrotransfusion") is one possible cause of the failure of combined pre- and postpartal anti-D prophylaxis. We analyzed the data from 391 patients who delivered at the UFK Freiburg in 1989. We evaluated the amount of fetomaternal bleeding in different modes of delivery. We observed fetomaternal hemorrhage of clinical relevance in 7.5% of spontaneous delivery, 11.1% of vacuum extraction, 17.7% of cesarean section (p less than 0.05). There was no difference concerning macrotransfusions in the above mentioned modes of delivery. Our data are compared with the data of the DFG multicenter trial "rhesus negative" (1965-79).

Cesarean Section↗