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Results for “Goal-directed control”

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Cannabis intoxication: effects of monetary incentive on performance, a controlled investigation of behavioural tolerance in moderate users of cannabis.

The study examined the effect of monetary incentive on the performance of five tasks after two heterogeneous groups of experienced users of cannabis and previously naive subjects had smoked placebo material and two dose levels of cannabis. The performance of the motivated subjects was compared with that of two non-motivated matched groups. Dose-related impairment was found on four of the five tasks, supporting previous findings of cannabis-induced impairment of short-term memory, goal-directed behavior and choice reaction times. Results for three of the tasks suggested that the performance of the motivated subjects was less affected by the drug than was the performance of the non-motivated subjects. There was no difference between the performance of subjects naive and experienced with respect to drug use.

Adult↗

Understanding motor events: a neurophysiological study.

Neurons of the rostral part of inferior premotor cortex of the monkey discharge during goal-directed hand movements such as grasping, holding, and tearing. We report here that many of these neurons become active also when the monkey observes specific, meaningful hand movements performed by the experimenters. The effective experimenters' movements include among others placing or retrieving a piece of food from a table, grasping food from another experimenter's hand, and manipulating objects. There is always a clear link between the effective observed movement and that executed by the monkey and, often, only movements of the experimenter identical to those controlled by a given neuron are able to activate it. These findings indicate that premotor neurons can retrieve movements not only on the basis of stimulus characteristics, as previously described, but also on the basis of the meaning of the observed actions.

Animals↗

Rapid elbow flexion in the absence of proprioceptive and cutaneous feedback.

Rapid goal-directed movements of elbow flexion were studied in normal human subjects and in patients deprived of proprioceptive and cutaneous feedback. All normal subjects showed a burst of electromyographic (EMG) activity in the extensor muscle (antagonist) that served to arrest the limb precisely in the target zone. The magnitude of this burst co-varied with the magnitude of the initial accelerating burst in the flexor muscle (agonist). In patients, there was a small decelerating burst poorly correlated with the agonist activity. All patients had difficulty to control the amplitude of their movements due to improper adjustment of the size and time of onset of the decelerating burst. It is concluded that the central nervous system can generate a sequence of commands to accelerate and decelerate a limb in the absence of peripheral feedback. However, information from the moving limb is required to adjust the magnitude and time of onset of deceleration.

Adult↗

Social problem-solving therapy for unipolar depression: an initial dismantling investigation.

Tests the efficacy of social problem-solving therapy for unipolar depression and examines the relative contribution of training in the problem-orientation component of the overall model. This process involves various beliefs, assumptions, appraisals, and expectations concerning life's problems and one's problem-solving ability. It is conceptually distinct from the remaining four problem-solving components that are specific goal-directed tasks. A dismantling research design, involving 39 depressed Ss, provides findings that indicate problem-solving to be an effective cognitive-behavioral treatment approach for depression, thereby extending previous research. Moreover, the results underscore the importance of including problem-orientation training.

Adaptation, Psychological↗

Behavior and the balance between norepinephrine and serotonin.

The functions of the central monoamines Norepinephrine (NE) and Serotonin (5HT) can be clarified by the study of behaviors of rats administered selective monoamine toxins. In his home environment the low NE rat has drive deficits and is lethargic, tending to remain in his burrow, but in novel environments this animal acts less frightened than Controls. The low 5HT rat is conversely active and exploratory in familiar environments but frightened in novel environments. These two animals model aspects of depression and anxiety, respectively. 5HT can be thought of as placing the brain into a state of consciousness appropriate for an animal in his nest (i.e., 5HT neurons act as relaxers), and as involved in a type of positive affect related to security, whereas NE neurons are dominant when an animal is vigilant, foraging out in the environment and are involved in a type of positive affect related to goal-directed approach arousal. Monoamine toxins may be produced when the behaviors elicited by these central neuronal systems are negatively reinforced (extinguished).

Affective Symptoms↗

[Prediction of goal-directed behavior: attitude, subjective behavioral competence and emotions].

Ajzen's (1985) theory of planned behavior explaining and predicting goal-directed behavior is extended by an emotional component. The extended theory of planned behavior is tested experimentally. N = 64 subjects play with two video games (a speed- and a problem-oriented game) under an achievement-motivational orientation. One half of the subjects plays both games in an easy version, the other half in a difficult version. The verbal emotional reactions to playing video games are grouped factor-analytically into an "activity emotion" and a "security emotion". Subjects playing video games in the difficult condition feel significantly more insecure, and perceive their behavioral control as significantly lower than subjects playing in the easy condition. Tests of the extended theory of planned behavior lead to significant squared multiple correlations for the dependent variables within the range of R2 = .20 to .58. The activity emotion accounts predominantly for a significant part of the variance of the attitude and the security emotion accounts for a significant part of the variance of the perceived behavioral control. No predictive power was found for the intention to play the games successfully.

Achievement↗

Using the OPTIMAL Theory to Optimize Aerodynamics in Respiratory Training for Healthy Adults and Individuals With Parkinson's Disease.

BACKGROUND: The OPTIMAL (Optimizing Performance Through Intrinsic Motivation and Attention for Learning) theory is a motor learning framework proposing that optimizing intrinsic motivation enhances motor performance and learning. The theory identifies three key components-Enhanced Expectancies (EE), Autonomy Support (AS) and External Focus of Attention (EF)-which facilitate more efficient, goal-directed movement. These components have been shown to improve motor outcomes in limb-based tasks; however, their application to respiratory training, particularly in clinical contexts such as voice and swallowing therapy in patients with Parkinson's disease (pwPD), has not yet been systematically explored. AIMS: This study aimed to investigate whether implementing OPTIMAL theory strategies during a respiratory muscle strength training (RMST) task improves immediate respiratory motor performance in healthy adults and pwPD. Additionally, we aimed to examine the effects of these strategies on motivation and cognitive engagement. METHODS: This quasi-randomized, single-session trial included 47 participants: Healthy CONTROL (n = 17), Healthy OPTIMAL (n = 16) and PD OPTIMAL (n = 14). Healthy participants were quasi-randomly assigned to either intervention or control conditions, whereas pwPD completed the intervention only. All participants completed a single respiratory session that included baseline, practice and retention phases. Outcome measures included peak expiratory flow, cough peak expiratory flow, cognitive engagement (EEG-based Cognitive Engagement Index) and self-administered motivation questionnaire. OUTCOMES AND RESULTS: Exhalation force improved from baseline to retention in the Healthy OPTIMAL group (baseline: M = 296 L/min; retention: M = 338 L/min; p < 0.001) and the PD OPTIMAL group (baseline: M = 315 L/min; retention: M = 370 L/min; p < 0.0001), but not in the Healthy CONTROL group (p > 0.05). No significant changes in cough strength were observed in any group. No correlations were found between cognitive engagement and exhalation force or motivation scores. However, motivation increased more in the Healthy OPTIMAL group (Questionnaire 1: M = 57.2; Questionnaire 2: M = 60.7) and the PD OPTIMAL group (Questionnaire 1: M = 60.1; Questionnaire 2: M = 62.8) than in the Healthy CONTROL group (Questionnaire 1: M = 61.1; Questionnaire 2: M = 62.5). CONCLUSIONS AND IMPLICATIONS: Implementing the OPTIMAL theory enhances immediate respiratory motor performance in both healthy participants and pwPD. OPTIMAL theory has clinical value in voice and swallowing therapy, although further research is needed to establish long-term efficacy and clinical impact. WHAT THIS PAPER ADDS: What is already known on the subject Motivation is a critical factor in rehabilitation. The OPTIMAL theory has been shown to improve both motivation and motor performance in limb-based tasks. Its impact on respiratory training, however, has not been previously examined. What this paper adds to the existing knowledge This study shows that applying OPTIMAL strategies during a respiratory muscle strength training task significantly improved peak expiratory flow in both healthy adults and people with Parkinson's disease. What are the potential or clinical implications of this work? Integrating the OPTIMAL theory principles into respiratory therapy may enhance motor outcomes, supporting voice, swallowing and cough rehabilitation.

Humans↗

From syndrome to illness: delineating the pathophysiology of schizophrenia with PET.

The Section on Clinical Brain Imaging of the Laboratory of Cerebral Metabolism has been engaged in studying regional brain metabolism by positron emission tomography (PET) to establish the pathophysiology of schizophrenia. Recent studies have revealed that the fluorodeoxyglucose (FDG) PET methodology can be applied successfully to determine the anatomical substrata of directed attention. In normal controls, the metabolic rate in the middle prefrontal cortex, measured during the ongoing performance of auditory discrimination, is associated with their accuracy of performance. In unmedicated patients with schizophrenia, even those who performed as well as normals, the metabolic rate in the mid-prefrontal cortex was found to be significantly lower than normal. Further, this decreased metabolic rate was unrelated to performance. In medicated patients with schizophrenia, at least part of the metabolic deficit remains, but this deficit appears to be performance-related. These findings suggest several conclusions. The mid-prefrontal cortex and its dopamine neurotransmitter pathway input are important biological determinants of sustained attention. Two types of prefrontal metabolic deficits may contribute to dysfunctional goal-directed behavior and, more speculatively, vulnerability to psychosis in some patients with schizophrenia. One deficit is sensitive to neuroleptics, and thus presumably to a change in the balance of regional brain dopamine input. A second deficit is unaffected by neurolpetic treatment.

Brain↗

A neural network model for the intersensory coordination involved in goal-directed movements.

A neural network model for a sensorimotor system, which was developed to simulate oriented movements in man, is presented. It is composed of a formal neural network comprising two layers: a sensory layer receiving and processing sensory inputs, and a motor layer driving a simulated arm. The sensory layer is an extension of the topological network previously proposed by Kohonen (1984). Two kinds of sensory modality, proprioceptive and exteroceptive, are used to define the arm position. Each sensory cell receives proprioceptive inputs provided by each arm-joint together with the exteroceptive inputs. This sensory layer is therefore a kind of associative layer which integrates two separate sensory signals relating to movement coding. It is connected to the motor layer by means of adaptive synapses which provide a physical link between a motor activity and its sensory consequences. After a learning period, the spatial map which emerges in the sensory layer clearly depends on the sensory inputs and an associative map of both the arm and the extra-personal space is built up if proprioceptive and exteroceptive signals are processed together. The sensorimotor transformations occurring in the junctions linking the sensory and motor layers are organized in such a manner that the simulated arm becomes able to reach towards and track a target in extra-personal space. Proprioception serves to determine the final arm posture adopted and to correct the ongoing movement in cases where changes in the target location occur. With a view of developing a sensorimotor control system with more realistic salient features, a robotic model was coupled with the formal neural network. This robotic implementation of our model shows the capacity of formal neural networks to control the displacement of mechanical devices.

Algorithms↗

Visuomotor performance of normal and clumsy children. I: Fast goal-directed arm-movements with and without visual feedback.

The mechanisms underlying accuracy in fast goal-directed arm-movements were investigated in normal and clumsy children in two age-groups, six to seven and 10 to 11 years. Clumsy children in both age-groups had a longer movement time than normal children; this difference increased slightly when there was visual feedback. For both normal and clumsy children, the relative variability of the total distance moved was smaller than that of the distance moved during acceleration, indicating a variability reduction mechanism in the course of a movement. In the six- to seven-year-old group, the relative variability of the distance moved during acceleration and of the total distance was larger for clumsy than for normal children; this did not reach significance in the 10- to 11-year-old group. It is suggested that motor difficulties are linked to inaccuracy in open-loop control processes and to less efficient use of visual feedback.

Age Factors↗

Human saccadic eye movements in the absence of the geniculocalcarine projection.

This paper describes the results of an investigation into the spatial and temporal properties of the saccadic eye-movement system in a subject with a 'blind' hemifield caused by accidental damage to the left geniculostriate projection. The results show that blind hemifield stimulation can elicit goal-directed saccades of short latency provided the contrast of the visual stimulus is above the threshold required for saccade generation at the corresponding stimulus eccentricity. Signal processing associated with blind hemifield pathways shows reduced sensitivity by comparison with the normal hemifield and greater dependence on stimulus size, eccentricity and mode of presentation. Higher contrast levels are always needed for blind field stimulation and larger variance in mean saccadic amplitudes and latencies is normally observed. Large stimulus eccentricities which would normally require corrective saccades exhibit a different response pattern to that observed in normal vision. The results show that the centre of gravity effect and the generation of rapid, 'express-saccades' observed in normal vision are not inevitable outcomes of midbrain processing of visual information. The subject's performance reveals strategic patterns of eye-movement responses which maximize the use of his normal hemifield. Visual performance in the control of saccadic eye-movement responses appears to be optimum when the detection of the visual stimulus is associated with both the geniculostriate and the midbrain pathways. Experiments designed to test for the effects of light scatter into the normal hemifield show that the subject's saccadic eye-movement performance following visual stimulation of the blind hemifield cannot be attributed either to the amount or the pattern of light scatter into the normal hemifield. The implications of present findings on the results of other studies of eye-movements in subjects with scotomas associated with cortical lesions are also examined.

Adult↗

Spared-root deafferentation of a cat's hindlimb: hierarchical regulation of pathways mediating recovery of motor behavior.

Previous studies showed that after complete hindlimb deafferentation in cats, the ipsilateral descending pathways mediated recovery of overground, goal-directed locomotion and accurate placement of the deafferented limb. In the present study deafferentations sparing one dorsal root (L6) were performed to see if the descending systems would still be responsible for the recovery. The partially deafferented hindlimb is initially impaired in postural reflexes and accurate placement during locomotion but considerable recovery occurs. A similar pattern of severe impairment and subsequent recovery is observed in cats in which the only lesion is L1 hemisection. When a hemisection is added 6 months later to chronic spared-root deafferentation the recovery (from the latter lesion) is temporarily reversed but the animals recover again in a fashion similar to that after hemisection alone. Since there is no recovery of overground locomotion when hemisection is added to complete deafferentation but there is when deafferentation is incomplete, the descending pathways apparently are not responsible for maintaining the recovery when one dorsal root is spared as they are when all are cut. The results suggest that a competitive or hierarchical control over residual systems may regulate recovery of motor function.

Animals↗

Effects of weak antagonist on fast elbow flexion movements in man.

By using a mathematical model and experiments involving electrical simulation of antagonistic muscles, we have formed the hypothesis (Wierzbicka et al. 1986) that in one-joint movements the antagonist muscle not only provides braking torque but also controls movement time. To get additional experimental support for this hypothesis, we studied elbow flexion movements performed by patients with spinal cord injury at the C5-6 level who had relatively normal strength in their biceps muscle and little or no voluntary control of the triceps. Seven quadriplegic patients and six control subjects performed elbow flexion movements of 10 degrees, 20 degrees, and 30 degrees "as fast and accurately as possible". Despite the lack of antagonist, patients used the same "pulse height" strategy as control subjects to scale their responses with movement amplitude. However, patients' movement time was on average twice that of control subjects, and durations of both accelerative and decelerative phases of movement were increased. Movement speed and acceleration were reduced to 20-50% of the corresponding values of control subjects. Patients tended to overshoot the target to a larger extent than control subjects, particularly 10 degrees targets, with nearly twice the error. We performed the same experiments using an external torque motor to assist the weak triceps. When a constant extensor torque of 2.5 or 5 Nm was provided by the motor, patients were able to move faster, and movement accuracy improved to within the normal range. These results provide direct evidence that the lack of an antagonist has an important effect on completion time and accuracy of fast goal-directed movements.

Adult↗

Intention and outcome: key components of causal structure facilitating mapping in children's analogical transfer.

The consequences of two key features of causal structure in source stories, intention and positive outcome, for analogical transfer were examined in kindergarten and second graders. In Experiment 1, children received either structure-complete, structure-incomplete, or irrelevant source stories. Structure-incomplete stories lacked either the intention to solve a problem (a goal-directed component), evidence of a successful consequence (an outcome-related component), or both as part of the solution activity described in source stories. Evidence for transfer was obtained for second graders when a goal-directed component, and to a lesser extent, an outcome-related component were connected to the solution action in source stories. Differences among conditions for kindergartners were less evident, although they revealed a pattern of performance similar to the second graders. A second experiment was conducted to determine whether memory and an orientation to use the source story information might account for these findings. Efforts to ensure memory for and hints to use information in the source stories, however, did not benefit solution transfer when intention and positive outcome were absent. These results suggest that a complete causal structure, including goal and outcome, in source stories augments transfer in young children by promoting mapping of the analogical relationship between source stories and the target problem.

Achievement↗

Dynamic properties of human goal-directed arm movements.

In the present study, the velocity of pointing movements towards visual targets was analyzed. In accordance with the literature, tangential velocity was found to exhibit rather smooth, single-peaked profiles. In contrast, however, the profiles of the velocity components in the Cartesian coordinates of space were conspicuously multi-peaked, and suggestive of sums of a smooth curve and an oscillation. Oscillation frequency was 4-6 Hz, and its amplitude 200-600 mm/s; the phase shift between horizontal and vertical oscillation was about 180 degrees. The oscillation remained unaltered when the external load of the arm, the size of the visual target, or the required movement direction were changed. The relationship between the present findings and previously documented rhythmic properties of motor control is discussed, and it is concluded that the oscillations may have been generated by neural circuits with inherent oscillatory properties.

Acceleration↗

The effects of visuomotor training and tDCS stimulation on visuomotor integration and visual processing: an electrophysiological approach.

BACKGROUND: Visuomotor integration coordinates visual and motor cortical activity to produce goal-directed responses and can be indexed by Rolandic Mu-rhythm suppression and visual evoked potential (VEP) P100 parameters. Perceptual-motor training improves visuomotor performance, and transcranial direct current stimulation (tDCS) over primary motor cortex (M1) has been reported to enhance motor learning when paired with training. This study examined whether anodal M1 tDCS augments the effects of Senaptec visuomotor training in healthy adults. METHODS: Sixty participants were randomized to active anodal tDCS (five 10-minute sessions, 1&#xa0;mA; n&#xa0;=&#xa0;31) or sham (n&#xa0;=&#xa0;29) over M1 immediately before each Senaptec training session; 53 completed all sessions and post-testing. Outcomes were Mu-suppression ratios, VEP P100 latency and amplitude, and Senaptec measures of visual sensitivity and visuomotor control. RESULTS: Active tDCS produced no augmentation of any outcome, with no significant group&#xa0;&#xd7;&#xa0;time interaction for any measure, consistent across composite and task-level analyses. Training alone produced no change in Mu suppression or visuomotor control. By contrast, both groups showed significant training-related gains in visual sensitivity, including near-far quickness and stereopsis, accompanied by shorter P100 latencies and larger amplitudes, indicating more efficient early visual processing. CONCLUSIONS: A clear dissociation emerged: training produced robust improvements in early visual processing, whereas neither tDCS nor training altered sensorimotor (Mu) or visuomotor-control measures. The tDCS results should be interpreted cautiously given the modest dose and limited power to detect small effects, rather than as evidence of inefficacy. Tablet-based perceptual training enhanced visual processing independent of neuromodulation.

Humans↗

Goal-directed care: caring for aggressive nursing home residents with dementia.

1. Aggressive behavior in elders with dementia occurs most often during personal care. It is often a response to invasion of private space and may be prevented or reduced by interpersonal approaches that reflect a set of individualized goals for the resident. 2. Five resident goals for preventing or reducing aggressive behavior are to feel safe, to feel physically comfortable, to experience a sense of control, to experience optimal stress, and to experience pleasure. 3. These goals provide a framework for humane care that respects the personhood of the individual and minimizes the need for psychotropic medications and physical restraints.

Aged↗

The effects of task preference on performance during purposeful and nonpurposeful activities.

This study examined the number of repetitions, increase in heart rate, increase in blood pressure, and rating of perceived exertion of subjects performing the most-preferred and least-preferred tasks from a predetermined list under purposeful and nonpurposeful conditions. Twenty healthy women completed the four experimental tests in random order for a period of 10 min each. The results indicated that there was no significant interaction (p greater than .05) between task choice and condition, thus implying that the subjects' performance was not influenced by task preference regardless of whether the activity was purposeful or nonpurposeful. Comparisons between the purposeful and nonpurposeful conditions revealed that the increase in heart rate and rating of perceived exertion were significantly higher (p less than .05) during nonpurposeful activity for both the most-preferred and the least-preferred tasks. On the basis of these results, it is recommended that therapists use purposeful, or goal-directed, activities in their practice, even if they are unable to provide their patients with a choice of therapeutic tasks.

Adult↗