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Results for “Granuloma, Pyogenic”

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PubMed2004

Giant recurrent pyogenic granuloma on the face with satellitosis responsive to systemic steroids.

Pyogenic granuloma is a common benign skin tumour. However, giant recurrent pyogenic granuloma with satellitosis is relatively rare. We present a 52-year-old man who had recurrent gigantic pyogenic granuloma with satellitosis responsive to systemic steroids. Our case of recurrent pyogenic granuloma is interesting because of its clinical presentation, recurrence following surgical excision and its steroid responsiveness. Systemic steroids may be effective in treating recurrent giant pyogenic granulomas during their high-proliferation phase.

Antineoplastic Agents, Hormonal↗

PubMed1989

Two pyogenic granulomas arising in an epidermoid cyst.

Two pyogenic granulomas arising from the wall of an epidermoid cyst on the midback of a 62-year-old white man are reported. Histologically, each pyogenic granuloma was a polypoid sessile nodule that showed well-vascularized granulation tissue; edema; a mixed inflammatory infiltrate; an epidermal collarette; and a thinned, variably ulcerated epidermis. Although pyogenic granulomas may develop anywhere on the skin, this appears to be the first report of pyogenic granulomas in an epidermoid cyst.

Epidermal Cyst↗

PubMed1989

Intravenous pyogenic granuloma of the hand.

Intravenous pyogenic granuloma is a recently described counterpart of cutaneous pyogenic granuloma. We report the second known case of this entity in the orthopedic and hand surgery literature and describe the characteristic clinical and histologic findings associated with this rare benign tumor.

Adult↗

PubMedDate not supplied

Pyogenic granuloma of the penile shaft following circumcision.

Pyogenic granuloma is a benign vascular, inflammatory proliferation that appears following minor trauma in children. The exact pathogenesis of pyogenic granuloma is unknown, but its formation is closely related to minor trauma, chronic irritation, and hormonal influences. We present a unique case of a pyogenic granuloma that appeared in an infant following circumcision.

Circumcision, Male↗

PubMed1995

Eruptive pyogenic granulomas: a successfully treated patient and review of the literature.

Pyogenic granuloma, also known as lobular capillary haemangioma, is a solitary, benign vascular skin tumour. Although a single pyogenic granuloma is common, multiple eruptive pyogenic granulomas are extremely rare. We report the occurrence of multiple, eruptive pyogenic granulomas in a previously healthy 17-year-old girl. Over 200 lesions appeared spontaneously over an 8-month period. Lesions were initially treated with cryotherapy, and then with the pulsed dye laser, resulting in their complete clearance.

Adolescent↗

PubMed1996

Pyogenic granuloma associated with guided tissue regeneration: a case report.

A pyogenic granuloma is an exuberant growth of granulation tissue secondary to irritation. Intraorally, it can present with a wide array of clinical appearances, ranging from a sessile lesion to an elevated mass. Pyogenic granulomas generally are soft, painless, and deep red to reddish-purple in color. They are usually 0.5 to 1.0 cm in diameter, more common in females, and often found on the keratinized tissue. This case is interesting because the pyogenic granuloma was found associated with guided tissue regeneration and the lingual alveolar mucosa. The lesion arose after demineralized freeze dried bone allograft and an expanded polytetrafluoroethylene (ePTFE) membrane were utilized to repair osseous defects. Five weeks after surgery, the patient presented for routine follow-up where suppuration associated with the membrane was noted along with an exophytic growth of the lingual alveolar mucosa. The ePTFE membrane was removed alone with an excisional biopsy of one of the growths. By 10 days after the removal of ePTFE, the lesion spontaneously healed. Histologic evaluation of the tissue was consistent with a pyogenic granuloma. This is the first case in the literature of a pyogenic granuloma associated with a routine guided tissue regenerative surgery using a non-resorbable membrane and allograft.

Adult↗

PubMed2005

Pyogenic granuloma of the sigmoid colon.

Pyogenic granuloma (PG) is a polypoid form of lobular capillary hemangioma that usually occurs in the skin and some mucosal surfaces. However, it is extremely rare in the intestinal tract and its preoperative diagnosis is difficult. We report on a case of PG of the sigmoid colon in a 62-year-old woman with a 6-month history of rectal bleeding. A pedunculated polypoid lesion was detected by colonoscopy and a polypectomy was performed. A microscopical study revealed a lobular arrangement proliferation of varying sizes of capillaries within an edematous stroma. A critical review of the English literature yielded only another well-documented case of PG in the large intestine. Diagnostic consideration includes inflammatory polyp and other vascular tumors such as bacillary angiomatosis and the angiomatous variant of Kaposi's sarcoma. Precise recognition of this distinctive vascular neoplasm in the gastrointestinal tract is essential to avoid misdiagnosis and inappropriate treatment.

Colon, Sigmoid↗

PubMedDate not supplied

Pyogenic granuloma with multiple dissemination in a burn lesion.

Pyogenic granuloma is a common vascular lesion in childhood. The occurrence of pyogenic granulomas after various kinds of trauma to the skin is quite common; however, multiple lesions secondary to a burn are very rare. For this reason, an 18-month-old girl with multiple pyogenic granulomas following a second-degree burn is reported.

Burns↗

PubMed1995

Multiple giant disseminated pyogenic granuloma in three patients burned by boiling milk.

BACKGROUND: Pyogenic granuloma is a common benign skin tumor. The multiple disseminated form of the disease is relatively rare. METHODS: We examined three patients who developed giant pyogenic granuloma after burns from boiling milk. The patients were a 1.5-year-old boy, a 5-year-old girl, and a 35-year-old woman, All three patients had second-degree burns over their face and trunk. RESULTS: In these patients, pyogenic granuloma had developed over the previously burned areas 2-3 weeks after exposure. The general condition of the patients remained good and all lesions involuted spontaneously. In a 6-month follow-up period no relapse of the lesions was seen. CONCLUSIONS: The cause for development of multiple giant pyogenic granulomas after burns from milk remains unknown, but milk proteins or other components of milk, microorganisms, or the burn itself may be causative factors.

Adult↗

PubMed2002

A giant pyogenic granuloma in the nasal cavity caused by nasal packing.

Pyogenic granuloma is a benign, rapidly growing hemorrhagic lesion of unknown origin. This disorder, however, is obscure to many rhinologists, because the nose is a relatively rare location for the lesion. In the practice of otorhinolaryngology, nasal packing is a very common procedure for nasal bleeding and postoperative hemostasis. However, few pyogenic granulomas occurring from nasal packing have been reported in the literature. A 56-year-old man underwent nasal packing with vaseline gauze because of nasal bleeding. Two months later, a dark brown nasal tumor was found in his nasal cavity. He underwent endoscopic endonasal removal of the tumor. The pathology result showed a pyogenic granuloma. This is the third case recorded in the literature of a confirmed pyogenic granuloma occuring as a complication of nasal packing. This uncommon lesion should be considered in the differential diagnosis of a rapidly growing hemorrhagic lesion within the nasal fossa.

Bandages↗

PubMed2000

Pyogenic granuloma (pregnancy tumor) of the nasal cavity. A case report.

BACKGROUND: Pyogenic granuloma is a benign lesion of unknown etiology that occurs in the skin and mucous membranes. It has been reported as a common lesion of the oral cavity and, less commonly, the nasal cavity. Although its etiology is unclear, pyogenic granuloma has long been associated with pregnancy, oral contraceptives and trauma. The term pregnancy tumor has been used to reflect the association with pregnancy; nevertheless, pyogenic granuloma is often misdiagnosed in obstetric patients. CASE: We present the case of a 37-year-old, pregnant woman with an enlarging nasal mass ultimately diagnosed as pyogenic granuloma. The patient was treated successfully with endoscopic excision of the lesion. CONCLUSION: Pyogenic granuloma is a rapidly growing lesion that should be considered in the differential diagnosis of any gravid patient with a mass in the oral or nasal cavity. The lesion may result in complications of the pregnancy, and management should be individualized for each patient.

Adult↗

PubMed1987

Pyogenic granulomas.

Four cases of conjunctival pyogenic granuloma are described. The patients ranged in age from 12-30 years. Surgical trauma preceded the development of two lesions in one patient and a second patient presented with a positive history of recurrent styes, a chalazion, and a questionable history of trauma to the lid. The other two patients had no known antecedent events that would explain development of the lesions. A review of the literature is included in the discussion, which details the etiology, incidence, clinical presentation, histopathology, symptoms, clinical course, differential diagnosis, and treatment of pyogenic granulomas.

Adolescent↗

PubMed2003

Pyogenic granuloma appearing on port-wine stain: a case report.

BACKGROUND: Pyogenic granuloma has been reported to be associated with hemangiomas and hamartomas, including port-wine stain. It has been suggested that the spontaneous development of pyogenic granuloma in port-wine stain might be associated with microscopic arteriovenous anastomoses in highly vascularized areas such as the fingers, hands, lips, tongue and face. CASE REPORT: A 25-year-old male patient presented with a history of a reddish, solitary nodule on the posterior cervical area for eight months. There had been an associated port-wine stain at the same localization since birth. Physical examination revealed a solitary, strawberry-like dome-shaped papule, 12 mm in diameter, within a well-demarcated reddish colored surrounding patch which had been present on the posterior cervical area. The lesion was excised, considering pyogenic granuloma arising in a port-wine stain. Histopathologic examination showed a mass of capillaries with variable luminal diameters, infiltration of inflammatory cells, and immature endothelial proliferation in the upper dermis. The capillaries were organized into lobules separated by fibrous stroma and were surrounded by an epithelial collarette. Immunohistochemical staining for factor VIII-related antigen supported all these findings of the port-wine stain. CONCLUSION: We present a pyogenic granuloma arising in port-wine stain on the posterior cervical area, since the posterior cervical area is not as highly vascular as the fingers, hands, lips, tongue and face. We believed that the collar of the patient's shirt continuously traumatized port-wine stain, and consequently led to the development of pyogenic granuloma.

Adult↗

PubMedDate not supplied

Multiple giant disseminated pyogenic granuloma in a burn lesion.

This case describes a 2-year-old boy who developed multiple giant pyogenic granulomas on his left upper extremity secondary to a burn injury caused by boiling milk. Here, we present multiple pyogenic granulomas in a burn patient and discuss the possible etiologies of the entity. The pyogenic granulomas were excised and wounds closed with sutures (primary repair) (primary closure). No pyogenic granulomas have recurred after 11 months of follow-up. Pyogenic granuloma with multiple dissemination in a burn scar is an extremely rare occurrence, and there have been no reports of pyogenic granulomas caused by flame and other type of scalding burns such as hot water and oil. The case presented here was a burn injury caused by hot milk. The burn etiology, not the burn injury itself, is important because all similar cases have the same etiology. We thought that this may not be a coincidence and that milk proteins or other components of the milk might cause the development of pyogenic granuloma.

Arm↗

PubMed2003

The efficacy of silver nitrate cauterization for pyogenic granuloma of the hand.

PURPOSE: We report a series of pyogenic granulomas of the hand treated effectively in the office with silver nitrate cauterization. METHODS: Twelve patients with 13 pyogenic granulomas of the hand were treated. The average duration of symptoms was 2 months. Masses were removed bluntly, pressure was held proximal to the lesion to effect hemostasis, and the base of the lesion was cauterized with silver nitrate applicators. After treatment patients were instructed to keep the lesions absolutely dry for 2 weeks. RESULTS: Complete resolution of the pyogenic granuloma was achieved in 85% of patients after an average of 1.6 treatments (range, 1-3 treatments). CONCLUSIONS: Pyogenic granuloma of the hand can be treated simply and effectively with silver nitrate cauterization in the office setting.

Adult↗

PubMed1995

An intestinal counterpart of pyogenic granuloma of the skin. A newly proposed entity.

Pyogenic granuloma is a common disease in the skin, but it is extremely rare in the gastrointestinal tract except for the oral cavity. We have seen three lesions (from three patients) of an intestinal counterpart of pyogenic granuloma and have reviewed their clinicopathologic features. Macroscopically, all three lesions revealed a polypoid growth with either a sessile or pedunculated configuration. All had an ulceration on the top. Microscopically, all these lesions were composed of a lobular proliferation of varying sizes of capillaries with an edematous stroma. Endothelial cells of the capillaries were swollen variously and in one case revealed a few mitotic figures. An inflammatory process was associated with the presence of ulcerations. Immunohistochemically, both Factor VIII-related antigen and QB-end/10(CD34) were positive only for the endothelial cells in all three cases. The characteristic macroscopic and histologic features thus allow for an early diagnosis of pyogenic granuloma in the gastrointestinal tract, which is similar to that observed in the skin.

Aged↗

PubMed1997

Treatment of pyogenic granuloma in children with the flashlamp-pumped pulsed dye laser.

OBJECTIVE: Pyogenic granuloma is a common, acquired, vascular tumor of the skin in children, often ulcerates or bleeds, and is commonly localized to the face. The treatment of choice has been surgical removal, either by excision or shave, followed by electrocautery. The site, young age of the patient, and the inherent nature of surgical removal or electrocautery often make this procedure a traumatic experience. Also, surgical treatment usually leads to permanent scarring. Owing to the pulsed dye laser's ability to cause selective destruction of superficial capillary-sized cutaneous blood vessels, its ease of operation, and its lack of scarring, we evaluated its use in the treatment of pyogenic granuloma in children. METHODS: Twenty-two children with solitary pyogenic granulomas were treated with a vascular-specific (585 nm), pulsed (450 microseconds) dye laser using a 5-mm spot size with a laser energy of 6 to 7 J/cm2 without anesthesia. Retreatments were administered every 2 weeks if necessary until the lesion cleared. Posttreatment care consisted of twice-a-day application of bacitracin ointment. RESULTS: In 20 patients (91%), laser treatment was successful. Five patients (25%) required one treatment for resolution, eight patients (40%) required two treatments, and six patients (30%) required three treatments for clearing. One patient required six treatments before the lesion resolved. There was no correlation with the duration, or site of the lesion, with respect to the number of laser treatments required. Lesions in all 20 children healed without scarring and with excellent cosmetic results. In two patients (9%), laser treatment failed in that there was no response to the initial laser treatment on follow-up 2 weeks later. Both had large pyogenic granulomas (1 cm and .5 cm in diameter, respectively) which were elevated over .5 cm above the surface of the skin. These lesions were surgically removed. None of the patients had a recurrence during the follow-up period of 6 months to 3 years. CONCLUSION: Pulsed dye lasers are effective and safe for the treatment of small pyogenic granulomas in children and should be considered a treatment option.

Adolescent↗

PubMedDate not supplied

Pyogenic granuloma as a presenting sign of hydroxyapatite orbital implant exposure: a clinicopathologic study.

PURPOSE: We report 5 unusual cases of exposed hydroxyapatite orbital implants that presented as pyogenic granulomas. We propose pathogenesis and histopathologic correlations. METHODS: A clinicopathologic study of 5 patients with hydroxyapatite implants who presented with pyogenic granuloma. RESULTS: Pyogenic granulomas were detected 1.5 to 30 months after implantation in 5 patients. The lesions were multiple but were not related to the wound margin at the exposed area and were not covered by the surface epithelium in most instances. Exposure defects were detected in all patients at the time of lesion excision. The mean exposure size in the greatest dimension was 16 mm (range, 9-20 mm). Three patients were treated successfully with simple excision of the granulomas, burring down of the anterior surface of the implants, and direct repair of the exposure defects. Explantation of the implant was performed in 2 cases. Histopathologic examination revealed chronic inflammation and microabscess formation in the explanted implants. CONCLUSIONS: Five patients with pyogenic granulomas were found to have hydroxyapatite exposure. Pyogenic granuloma should not be considered a benign lesion on a hydroxyapatite orbital implant, especially in recurrent cases. Ophthalmologists must be aware of the possibility of conjunctival dehiscence with hydroxyapatite-implant exposure beneath the lesion.

Adolescent↗