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Results for “Helplessness, Learned”

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PubMed1990

Learned helplessness in diabetic youths.

Determined the relationships among the learned helplessness attributional style, depression, regimen adherence, and metabolic control in a sample of diabetic youth. Fifty children (20 male and 30 female) between the ages of 10 and 16 completed the Children's Attributional Style Questionnaire and the Children's Depression Inventory. Regimen adherence was assessed with three 24-hr recall interviews conducted separately with patients and their mothers over a 1-week period. Metabolic control was measured by glycosylated hemoglobin A1 (HbA1). Learned helplessness was significantly associated with depression (p less than .001) and HbA1 (p less than .02), but was not associated with regimen adherence. Depression was unrelated to regimen adherence and metabolic control. The adherence measures together accounted for 24% of the variance of HbA1. Significant correlations were obtained between HbA1 and the exercise (p less than .05) and eating/testing frequency (p less than .05) adherence factors, indicating that lower levels of adherence were associated with worse metabolic control. Age, pubertal status, sex, disease duration, and SES were unrelated to regimen adherence and metabolic control. These results support the notion that the learned helplessness attributional style for negative events is related to both depression and long-term metabolic control problems in diabetic youths.

Adolescent↗

PubMed1996

Learned helplessness in the multiple sclerosis population.

The purpose of this cross-sectional, descriptive study was to describe the relationships between learned helplessness and disease status, functional and social disability, and disease activity in the multiple sclerosis population. Additionally, the relationships between learned helplessness and age, disease duration, education and marital and employment status were evaluated. Self-report instruments with established validity and reliability in the multiple sclerosis population were used to collect the data. Learned helplessness was significantly positively correlated with social and functional disability. Although not significant at the .05 level, disease status and disease activity were also positively correlated with learned helplessness. Additionally, unemployed individuals were more likely to be helpless than employed individuals. Overall, the results suggest that learned helplessness is related to negative health indicators in the multiple sclerosis population. Nursing interventions to decrease or prevent learned helplessness may be appropriate in this population.

Activities of Daily Living↗

PubMed1986

Learned helplessness as conditioned inattention to the target stimulus.

Learned helplessness theory explains the impaired performance that follows exposure to uncontrollable outcomes by assuming learned expectation of response-outcome independence that is transferred between tasks. Recent evidence has shown that introducing a second neutral stimulus, contingent on the offset of the uncontrollable stimulus, removes the subsequent interference. This finding has been claimed to support the view that the interference is a result of conditioned inattention rather than of the expectation of response-outcome independence. These conflicting explanations were examined in a series of four experiments that varied induction procedures (passive exposure or inescapability) and stimulus quality (aversive or nonaversive). All four experiments found the predicted interference, but only one, in which passive exposure was combined with an aversive stimulus, obtained results supporting the conditioned inattention hypothesis. We conclude that learned helplessness probably involves more than a single mechanism and that the passive exposure procedure may not be appropriate for demonstrating genuine helplessness deficits.

Adult↗

PubMed2005

Gene expression profiling in the hippocampus of learned helpless and nonhelpless rats.

In the learned helplessness (LH) animal model of depression, failure to attempt escape from avoidable environmental stress, LH, indicates behavioral despair, whereas nonhelpless (NH) behavior reflects behavioral resilience to the effects of environmental stress. Comparing hippocampal gene expression with large-scale oligonucleotide microarrays, we found that stress-resilient (NH) rats, although behaviorally indistinguishable from controls, showed a distinct gene expression profile compared to LH, sham stressed, and naïve control animals. Genes that were confirmed as differentially expressed in the NH group by quantitative PCR strongly correlated in their levels of expression across all four animal groups. Differential expression could not be confirmed at the protein level. We identified several shared degenerate sequence motifs in the 3' untranslated region (3'UTR) of differentially expressed genes that could be a factor in this tight correlation of expression levels among differentially expressed genes.

Adaptor Proteins, Vesicular Transport↗

PubMed1999

The role of US signal value in contingency, drug conditioning, and learned helplessness.

In Pavlovian conditioning, organisms can learn that a conditioned stimulus (CS) signals the delivery of an unconditioned stimulus (US). The present paper first reviews research showing that organisms can also learn that a stimulus, normally considered to be a US, signals the delivery of another US. Second, the paper shows how such signal value may contribute to three conditioning phenomena that are of interest to many psychologists: contingency, drug conditioning, and learned helplessness. In addition to showing how such signal value may contribute to these three phenomena, suggestions for further research, as well as current gaps in the knowledge base, are outlined.

Alcoholism↗

PubMed1983

Learned helplessness in the gerbil?

Evidence of learned helplessness was demonstrated in Mongolian gerbils. Two consecutive days of jump-up escape were followed 24 hr later by testing in a bar-press escape task. Reliable differences occurred between escapable and inescapable animals and between inescapable and control animals.

Animals↗

PubMed1993

Learned helplessness and in vivo hippocampal norepinephrine release.

Hippocampal norepinephrine release was measured using in vivo microdialysis in rats before and after exposure to inescapable tail shock stress and after testing for learned helplessness. Rats that did not develop learned helplessness after stress had higher basal norepinephrine release after stress than rats developing learned helplessness or than control rats. After the shuttlebox test for learned helplessness, K(+)-stimulated norepinephrine release was lower in learned helpless than in nonhelpless or control rats. These results confirm an important role for the hippocampal noradrenergic system in differential behavioral responses to stress.

Animals↗

PubMed2005

Learned helplessness: validity and reliability of depressive-like states in mice.

The learned helplessness paradigm is a depression model in which animals are exposed to unpredictable and uncontrollable stress, e.g. electroshocks, and subsequently develop coping deficits for aversive but escapable situations (J.B. Overmier, M.E. Seligman, Effects of inescapable shock upon subsequent escape and avoidance responding, J. Comp. Physiol. Psychol. 63 (1967) 28-33 ). It represents a model with good similarity to the symptoms of depression, construct, and predictive validity in rats. Despite an increased need to investigate emotional, in particular depression-like behaviors in transgenic mice, so far only a few studies have been published using the learned helplessness paradigm. One reason may be the fact that-in contrast to rats (B. Vollmayr, F.A. Henn, Learned helplessness in the rat: improvements in validity and reliability, Brain Res. Brain Res. Protoc. 8 (2001) 1-7)--there is no generally accepted learned helplessness protocol available for mice. This prompted us to develop a reliable helplessness procedure in C57BL/6N mice, to exclude possible artifacts, and to establish a protocol, which yields a consistent fraction of helpless mice following the shock exposure. Furthermore, we validated this protocol pharmacologically using the tricyclic antidepressant imipramine. Here, we present a mouse model with good face and predictive validity that can be used for transgenic, behavioral, and pharmacological studies.

Animals↗

PubMed1987

Three accounts of the learned helplessness effect.

Two experiments tested predictions drawn from test anxiety theory, learned helplessness theory, and Wortman and Brehm's (1975) integration of helplessness and reactance theories. Experiment 1 demonstrated that performance deficits predicted by learned helplessness do not rely on experimenter-induced failure. It also showed such deficits to be unrelated either to negative affect following exposure to pretreatment or to causal attributions about pretreatment task performance. Experiment 2 showed that experience of uncontrollability need not result in impaired performance, because failure on an unimportant task did not produce the deficits predicted by learned helplessness theory. This result provides qualified support for the integrative model. Finally, because the subjective measures used in Experiment 2 were not consistent with performance measures, the reliability of self-reports is questioned.

Achievement↗

PubMed2006

Learned helplessness is independent of levels of brain-derived neurotrophic factor in the hippocampus.

Reduced levels of brain-derived neurotrophic factor (BDNF) in the hippocampus have been implicated in human affective disorders and behavioral stress responses. The current studies examined the role of BDNF in the behavioral consequences of inescapable stress, or learned helplessness. Inescapable stress decreased BDNF mRNA and protein in the hippocampus of sedentary rats. Rats allowed voluntary access to running wheels for either 3 or 6 weeks prior to exposure to stress were protected against stress-induced reductions of hippocampal BDNF protein. The observed prevention of stress-induced deceases in BDNF, however, occurred in a time course inconsistent with the prevention of learned helplessness by wheel running, which is evident following 6 weeks, but not 3 weeks, of wheel running. BDNF suppression in physically active rats was produced by administering a single injection of the selective serotonin reuptake inhibitor fluoxetine (10 mg/kg) just prior to stress. Despite reduced levels of hippocampal BDNF mRNA following stress, physically active rats given the combination of fluoxetine and stress remained resistant against learned helplessness. Sedentary rats given both fluoxetine and stress still demonstrated typical learned helplessness behaviors. Fluoxetine by itself reduced BDNF mRNA in sedentary rats only, but did not affect freezing or escape learning 24 h later. Finally, bilateral injections of BDNF (1 mug) into the dentate gyrus prior to stress prevented stress-induced reductions of hippocampal BDNF but did not prevent learned helplessness in sedentary rats. These data indicate that learned helplessness behaviors are independent of the presence or absence of hippocampal BDNF because blocking inescapable stress-induced BDNF suppression does not always prevent learned helplessness, and learned helplessness does not always occur in the presence of reduced BDNF. Results also suggest that the prevention of stress-induced hippocampal BDNF suppression is not necessary for the protective effect of wheel running against learned helplessness.

Animals↗

PubMed1979

[Depression and learned helplessness in humans].

The learned helplessness hypothesis as a model of human depression is rather unknown in the journals of german language. This article wants to remove that ignorance and make known that experimentalclinical model of depressive behavior. We want further to stimulate empirical and experimental research. In recent advances attributional and cognitive reflections and determinants got important. We introduce these new developments. Depressed persons attribute failures and negative experiences in an internal, global, and stabile way. A problematic cognitive circle develops and depression gets more intensive and chronically. Therapeutical and preventive implications are also discussed.

Depression↗

PubMed1997

Learned helplessness increases 5-hydroxytryptamine1B receptor mRNA levels in the rat dorsal raphe nucleus.

Learned helplessness is a behavioral condition induced by exposure to inescapable stress that models aspects of stress-related disorders including depression and posttraumatic stress disorder, and has been associated with diminished serotonin release in the rat frontal cortex. Our hypothesis was that presynaptic 5-hydroxytryptamine1B (5-HT1B) receptors, which inhibit the synthesis and release of serotonin in nerve terminals, may be increased in learned helplessness. Postsynaptic 5-HT1B mRNA hybridization levels in the hippocampus or frontal cortex were unchanged following induction of learned helplessness; however, presynaptic 5-HT1B mRNA hybridization signal in the dorsal raphe nucleus of helpless rats was 25% higher than control values. There was no change in dorsal raphe serotonin transporter mRNA level. The detection of increased 5-HT1B mRNA levels in the dorsal raphe nucleus suggests an increased capacity to synthesize presynaptic 5-HT1B receptors and could account for diminished serotonin neurotransmission in learned helplessness.

Animals↗

PubMedDate not supplied

A ganglionic model of "learned helplessness".

The phenomenon known as "learned helplessness" (LH) is seen broadly across the animal kingdom. Some of the basic characteristics of this behavior are: failure to escape shock when it is possible to do so following non-escapable shock; reversion to non-escape behavior even after successful escape; if the animal is given escape/avoidance training prior to being given inescapable shocks, the latter will not interfere with its ability to later show normal escape/avoidance behavior (generally described as an immunization effect); following inescapable shock training the animals often become "passive and still" when confronted with an inescapable shock. These behaviors are seen in intact mammals, lower vertebrates, and invertebrates. In fact, the basic characteristics are even seen in a spinal rat and, with the exception of one characteristic not yet examined, in an isolated thoracic ganglion of an insect. The brain is evidently not essential either in mammals or in invertebrates for demonstrating this behavior. Not only can an insect ganglion show the behavioral characteristics of LH, but the neural information underlying the phenomenon of LH can be shown to transfer from one ganglion innervating one pair of legs to another ganglion innervating a different pair of legs. Thus, how CNS information underlying LH is coded and transferred from one site to another within the CNS can be examined in such a system. The LH model has provided valuable insights into the physiology of depression. This model suggests that human depression is caused by one's lack of control over traumatic events. It is supported by a number of parallels between depression and LH behavior. Tricyclic antidepressants, MAO inhibitors, and ECT, which are effective in treating depression, also can prevent and reverse LH in mammals. It would be important to find out if they are also effective in invertebrate models. The fact that the characteristics of the behavior called LH are seen in invertebrates such as slugs, cockroaches, and locusts provokes other intriguing questions about the presence of cognition at these phylogenetic levels, as well as what animal or preparation constitutes an appropriate model for human depression.

Animals↗

PubMed2002

A Chinese version of the Rheumatology Attitudes Index is a valid and reliable measure of learned helplessness in patients with SLE.

Despite the prognostic importance of learned helplessness (LH) in rheumatic diseases, there are no validated measures of LH in Chinese or other Asian languages. We therefore assessed the validity of a Chinese translation of the Rheumatology Attitudes Index (CRAI; a widely used measure of LH) and its Helplessness (CHS) and Internality (CIS) subscales in patients with SLE. Chinese-speaking SLE patients (n = 69) completed identical, self-administered questionnaires containing the CRAI and assessing demographic/socio-economic variables twice within 2 weeks. SLE activity, damage and quality of life were assessed using the BILAG, SLICC/ACR Damage Index and SF-36 respectively. Scale psychometric properties were assessed through Cronbach's alpha, intra-class correlations, quantifying test-retest differences, factor analysis and known-groups construct validity. Internal consistency and reliability were acceptable, with Cronbach's alpha for the CHS, CIS and CRAI being 0.70, 0.69 and 0.74, respectively. Mean differences in test-retest scores spanned 1.6-2.4% of possible scale ranges and intra class correlations ranged from 0.72 to 0.88. Factor analysis identified two major factors corresponding to the CHS and CIS subscales of the CRAI. Eight of 10 a priori hypotheses relating the CRAI and CHS to demographic, disease and quality of life variables were confirmed, supporting the construct validity of these scales. The CRAI and its helplessness subscale are valid and reliable measures of learned helplessness in Chinese-speaking SLE patients.

Adolescent↗

PubMedDate not supplied

Development of a measure of learned helplessness.

The purpose of this study was to develop a measure of learned helplessness. Based on a review of the literature, 50 items were developed for inclusion in the proposed Learned Helplessness Scale (LHS). On the basis of independent reviews by three experts, 20 items were selected for inclusion in the LHS. An individual's response to each item was graded, using a Likert scale. A standardized alpha reliability coefficient of .85 was obtained for a sample of 241 healthy adults. There was a positive correlation between the LHS scores and Beck's Hopelessness Scale (HS) scores (r = .252) and a negative correlation between the LHS scores and Rosenberg's Self-Esteem Scale (SES) scores (r = -.622). These correlations were in the direction postulated by various theorists. A Varimax-rotated factor analysis of the LHS data yielded five factors. Three of these factors tapped content relevant to the attributional styles of learned helplessness. Clinical data were also obtained on samples of oncology, hemodialysis, and spinal cord patients. Because the alpha reliability coefficients of the LHS and the Pearson product moment correlation coefficients between the LHS and the HS and the LHS and the SES were in the same direction, the instrument is believed to have adequate internal consistency.

Adolescent↗

PubMed1982

A re-view of cognitive mediators in learned helplessness.

The findings of Oakes and Curtis (1982), Tennen, Drum, Gillen, and Stanton (1982), and Tennen, Gillen, and Drum (1982) provide a challenge to learned helplessness theory's focus on cognitive mediators of the helplessness phenomenon. In response to these findings, Alloy (1982) argues that these studies do not challenge helplessness theory because they do not measure expected control and because they confuse necessary and sufficient causes of learned helplessness. Silver, Wortman, and Klos (1982) contend that these studies provide an inadequate test of the model because subjects are confronted with experiences which are unlike those in their natural environment. The present article argues that by Alloy's (1982) criteria, an adequate test of the learned helplessness model has not yet been conducted. Previous studies which measured expected control have not supported the model's predictions. Moreover, if perceived response-outcome independence is a sufficient, but not a necessary cause of learned helplessness, the model loses much of its heuristic value. In response to the argument that these studies lack ecological validity, this article clarifies the distinction between experimental realism and mundane realism. While real-world studies have discovered intriguing relations between perceptions of control, attributions, and coping with illness or victimization, they have not tested predictions of the learned helplessness model.

Affect↗

PubMed1983

Opiate antagonists overcome the learned helplessness effect but impair competent escape performance.

Rats exposed to inescapable shocks exhibited deficiencies in learning to escape shock in a novel situation 24 hours later (learned helplessness). Opiate antagonists (naloxone or naltrexone) blocked the learned helplessness effect, allowing efficient escape performance on the subsequent test. In contrast, these drugs impaired the performance of rats pretrained with escapable shocks and animals with no previous exposure to shock. Both effects occurred at small doses and increased substantially with higher doses. The results suggest a significant role for endogenous opiates in the induction of learned helplessness as well as in the acquisition of efficient escape behavior.

Animals↗

PubMed1989

Learned helplessness, test anxiety, and academic achievement: a longitudinal analysis.

The stability of individual differences in test anxiety and learned helplessness over a 2-year period and their relation to concurrent and future school achievement were examined. Several issues regarding the assessment of learned helplessness are also addressed. 82 children were administered measures of test anxiety and helplessness in the third grade and again in the fifth grade. Teachers also provided reports of learned helpless and mastery-oriented behaviors at these 2 grade levels. It was found that: (a) both self-report and teacher-report measures of helplessness were stable over the 2-year period; (b) helplessness in the third grade was related to achievement test scores in the fifth grade; and (c) teacher reports may be a viable means of identifying helplessness. These findings are discussed in terms of cognitive developmental changes in children's understanding of effort and ability, and their implications for the assessment of learned helplessness are outlined.

Achievement↗