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PubMed1986

DNA models for A, B, C and D conformations related to fiber X-ray, infrared and NMR measurements.

A conformational analysis of the A, B, C and D DNA forms was made in order to establish molecular models presenting a good agreement with experimental data obtained from fiber X-ray, infrared linear dichroism and 31P NMR. The proposed models have been refined and do present good stereochemistry and optimized H-bond distances between bases associated with the Watson-Crick pairing. The DNA conformations proposed are a left handed double helix for the C form and right handed helices for A, B and D. Relations to conformational transitions between these forms are discussed.

DNA↗
PubMedDate not supplied

[Near-infrared rays in tissue diagnosis].

The application of Near-Infrared Radiation provides the physician with a method of reaching a specific and non-invasive examination of internal body parts: Without addition of a contrast medium, the distributions of local haematocrit, namely the structures of mainly subcutaneous blood vessels, can be shown with continuity and good definition in the regions of focus (NIR-Microangiopathy, especially for peripheral body sections). This paper introduced a transmission method able to penetrate even thick sections (> 30 mm). A new, simple method to evaluate reflected NIR parts permits a non-invasive and exact localization of inhomogeneities in organic substances of certain consistency (for instance milk and blood) up to depth of 20 mm.

Animals↗