STUDIES ON THE PATHOGENESIS OF THE GENERALIZED SHWARTZMAN REACTION. II. ROLE PLAYED BY EXPERIMENTALLY INDUCED FIBRINOLYSIS.
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After a ten days pretreatment with testosteron-propyonate administration of vasopressin induces bilateral cortical necrosis of kidneys in rats. When testosteron and cyproteron-acetate an androgen-blocking agent were given simultaneously vasopressin did not induce necrosis of the renal cortices. These findings suggest that androgen receptors of the kidney may take a part in eliciting this phenomenon.
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