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At least 55 records · Page 3Linked to original sources

Variations of rates of vascular surgical procedures for chronic critical limb ischaemia and lower limb amputation rates in western Swedish counties. The Westcoast Vascular Surgeons (WVS) Study Group.

OBJECTIVE: To assess a possible covariation between vascular surgery and amputation rates for critical limb ischaemia in defined western Swedish populations. DESIGN AND SETTING: A retrospective study during 1 year of the total number of vascular reconstructions for chronic critical leg ischaemia and amputations in the western Sweden area of health care. MAIN OUTCOME MEASURES: Correlation between vascular reconstruction and amputation rates in subpopulations. RESULTS: Patients undergoing amputation were 6 years older and had a significantly higher degree of dependent living compared with those subjected to revascularisation. The annual vascular reconstruction rate for critical limb ischaemia varied between 2 and 45, and the amputation rate between 12 and 71 per 100,000 population in the different catchment areas. There was, however, no negative correlation between amputation and revascularisation rates. CONCLUSION: We failed to demonstrate a negative correlation between amputation and revascularisation rates. Patients undergoing vascular reconstruction and amputation may represent different populations. Catchment areas with high vascular surgical activity did not have correspondingly lower amputation rates.

Aged↗

Crash simulation of lower limb with motorcycle basket.

Lower limb injuries are the main cause of temporary and permanent disability among motorcyclists in Malaysia. They cause non-fatal but serious injuries requiring hospitalisation. Detailed studies on factors influencing lower limb injuries are justified in an attempt to reduce the occurrence of these injuries. This study presents a computer simulation of the crash behaviour of the basket of a small-engined motorcycle with the lower limb using finite element (FE) methods. The results suggest that the extensive deformation of the motorcycle basket may reduce the risk of injury to the lower limb. The behaviour of the basket during collision is analogous to the crumple zone of automobiles.

Accidents, Traffic↗

Biomechanical analysis of stair ambulation in lower limb amputees.

Lower extremity amputees have to cope with many activities in everyday life that are substantially more difficult than walking on level ground, and such demands require a high degree of functionality from their prosthetic components. The present study is a biomechanical evaluation (kinematics, kinetics and EMG) of stair ascent and descent in a group of eight transtibial amputees (mean (standard deviation): age 51(14) years, height 176(7)cm, mass 88(19)kg); a group of 12 transfemoral amputees (age 37(8) years, height 182(7)cm, mass 83(7)kg) fitted with the electronically controlled C-LEG knee joint system; and a group of 12 able bodied persons (age 30(10) years, height 174(12)cm, mass 69(12)kg). During stair descent the transfemoral amputees presented a strong reduction of the prosthetic ankle moments (0.11Nm/kg) compared to transtibial amputees (0.93Nm/kg) and control subjects (1.26Nm/kg). Loading of the prosthetic knee joint in the transfemoral amputees more closely resembles the loading seen in the control population when compared to transtibial amputees (mean maximum flexion moment: controls 1.31Nm/kg, transfemoral amputees 1.00Nm/kg, transtibial amputees 0.50Nm/kg). Overload of the contralateral limb is more prominent in the transfemoral amputee than in the transtibial amputee. During stair ascent, the transtibial amputee presents a significant reduction of the knee flexion moment compared to the controls (mean maximum flexion moment: transtibial amputees 0.28Nm/kg, controls 1.31Nm/kg). These differences correlate with a change in the muscle activity of the knee extensor and hamstring muscles. The results also show adaptations in motor strategies during stair negotiation, for those with the partial loss of a lower limb due to the functional limits of current prosthetic components. The present data may contribute to a further enhancement of the efficiency of prosthetic feet and knee joints.

Activities of Daily Living↗

[Accuracy of the term "diabetic angiopathy of the lower limbs". II. Possibilities of the morphological assessment of the stage of diabetic angiopathy of the lower limbs and the choice of treatment tactics].

In 40 patients with diabetic angiopathy of lower extremities of terminal stage the foot tissue biopsies were studied up using electron and light microscopy. A skin was supposed to be most acceptable substrate for biopsy because there was established morphological changes of tissues, occurring in a single direction and in a single type. Morphological criteria of the angiopathy stages were delineated, permitting to make a differentiative choice of the treatment tactics.

Adult↗

Chronic phantom sensations, phantom pain, residual limb pain, and other regional pain after lower limb amputation.

OBJECTIVES: To determine the characteristics of phantom limb sensation, phantom limb pain, and residual limb pain, and to evaluate pain-related disability associated with phantom limb pain. DESIGN: Retrospective, cross-sectional survey. Six or more months after lower limb amputation, participants (n = 255) completed an amputation pain questionnaire that included several standardized pain measures. SETTING: Community-based survey from clinical databases. PARTICIPANTS: A community-based sample of persons with lower limb amputations. MAIN OUTCOME MEASURES: Frequency, duration, intensity, and quality of phantom limb and residual limb pain, and pain-related disability as measured by the Chronic Pain Grade. RESULTS: Of the respondents, 79% reported phantom limb sensations, 72% reported phantom limb pain, and 74% reported residual limb pain. Many described their phantom limb and residual limb pain as episodic and not particularly bothersome. Most participants with phantom limb pain were classified into the two low pain-related disability categories: grade I, low disability/low pain intensity (47%) or grade II, low disability/high pain intensity (28%). Many participants reported having pain in other anatomic locations, including the back (52%). CONCLUSIONS: Phantom limb and residual limb pain are common after a lower limb amputation. For most, the pain is episodic and not particularly disabling. However, for a notable subset, the pain may be quite disabling. Pain after amputation should be viewed from a broad perspective that considers other anatomic sites as well as the impact of pain on functioning.

Adult↗

Gait adaptations during walking under visual and cognitive constraints: a study of patients recovering from limb-saving surgery of the lower limb.

The objective of this case series study was reautomatization of gait after limb-saving surgery for tumors at a laboratory of gait analysis. Twelve patients (9 males and 3 females; mean age, 38 years) who underwent limb-saving surgery of the lower limb at least 1 year previously and ten normal subjects (3 males and 7 females; mean age, 37.5 years) were studied. The main outcome measures were walking speed and stride time duration under normal walking conditions as well as the use of different types of constraints. Patients walked with a lower preferred walking speed than the normal subjects. Patients showed a higher coefficient of variation of stride time in normal walking as well as complex walking compared with normal subjects. During walking with constraints, a significant decrease in stride time was found in patients but not in normal subjects. Although restoration of gait after limb-saving surgery is impressive, it is not complete (lower walking speed) and can break down under conditions of visual and cognitive load. Hence, the application of complex tasks reveals that gait reautomatization is not complete in these patients during a period of 2 to 5 years after surgery.

Adult↗

Effect of stimulation of an upper limb on motor evoked potentials in lower limb muscles to transcranial magnetic stimulation in normal subjects and patients with thalamic infarction.

The effects of conditioning stimulation of an upper limb on motor evoked potentials (MEPs) of relaxed muscles in both lower limbs were studied in 7 normal subjects and two patients with left thalamic infarction. A possible mechanism for the Jendrassik maneuver (JM) is that induced proprioceptive input ascends supraspinally to facilitate the descending volleys. In order to mimic the JM with a more controlled influence, we used an electrical conditioning (C) stimulation (4 times sensory threshold) delivered to the left index finger preceding the transcranial (T) magnetic stimulation at C-T intervals of 0-200 ms. The MEP facilitation of bilateral tibialis anterior (TA) and gastrocnemius medialis (GC) was within C-T 70-110 ms. The peak facilitation was at C-T 80 ms for ipsilateral TA (309%) and GC (405%) and at C-T 90 ms for contralateral TA (207%) and GC (283%). In the two thalamic infarction patients with right-sided sensory loss, the facilitation did not occur when the conditioning stimulation was delivered to the affected index finger. Therefore, it is likely that the peripheral volley must be transmitted supraspinally to facilitate MEPs of the lower limbs. This method for studying sensory facilitation is more quantitative and reproducible than the JM and technically better than other previously described methods for somatosensory conditioning.

Adult↗

Bioimpedance analysis: potential for measuring lower limb skeletal muscle mass.

BACKGROUND: Ambulation, balance, and lower extremity bone mass and strength are all partially dependent on lower limb skeletal muscle mass. At present, both research and clinical methods of evaluating lower limb skeletal muscle mass as a component of nutrition assessment are limited. One potential simple and inexpensive method is lower extremity bioimpedance analysis (BIA). The present study had two objectives: to examine the determinants of lower limb resistance, with the underlying hypothesis that fluid-containing muscle is the main electrical conductor of the lower limbs; and to establish if a correlation of equivalent magnitude and similar covariates is observed when height squared (H2) is used instead of lower limb length squared (L2) in multiple regression models relating resistance to independent variables. METHODS: Lower limb resistance was measured using a contact-electrode BIA system, and lower limb fat and skeletal muscle were estimated by dual-energy x-ray absorptiometry in healthy adults. A physical BIA model was developed in the form of a regression equation with path-length (as L2 and H2)-adjusted resistance as dependent variables and lower limb skeletal muscle, fat, age, and gender as potential independent variables. RESULTS: There were 94 subjects, 34 men and 60 women, with a mean (-/+SD) age of 41.5+/-17.8 years. Strong associations were observed between L2/resistance and lower limb skeletal muscle, although for both men and women, age entered into the model as a significant covariate (total R2, men = .79 and women = .72; both p < .001). Similar models were observed with H2/resistance as dependent variable. Additional analyses showed a significantly lower resistance in lower limb skeletal muscle and height-matched old vs young subjects. CONCLUSIONS: Strong associations exist between measured lower limb resistance and lower limb muscle mass, adjusting for electrical path length either by L2 or H2. These observations suggest the potential of predicting skeletal muscle using BIA-measured lower limb resistance adjusted for stature. Age is also an independent variable in lower limb resistance-skeletal muscle associations, suggesting the need to establish underlying mechanisms of age-related resistance effects and to consider subject age when developing BIA prediction models.

Absorptiometry, Photon↗

Arterial embolectomy in lower limbs.

Arterial embolisms in the lower limbs occur frequently, and are of great interest to the vascular surgeon. The authors studied 159 cases of arterial embolisms in lower limbs from January 1991 to July 1993. Ages varied from 12 to 98, with a mean of 58. Eighty patients were male and 78 were female. In most cases, etiology of the embolus was well-established, and mainly caused (78 percent) by atrial fibrillation. Occlusion was most frequent in the femoral artery (53.4 percent). All patients presented severe lower limb ischemia, but not gangrene, on admission. The duration of ischemia, between the onset of symptoms and the liberation of arterial flow, was in most patients (67.9 percent) less than 24 hours. All patients were submitted to lower limb embolectomy with the Fogarty catheter, of which 70.9 percent were done through the femoral artery. Fasciotomy was performed on 48 patients due to a compartimental syndrome. Nineteen patients died immediately after operation; 68.4 percent due to heart failure. Twenty-three (16.4 percent) of the 140 surviving patients (150 operated limbs) were submitted to amputations after the occlusion of artery branches, which had undergone embolectomies. One hundred and twenty-seven limbs (84.6 percent) were preserved in 117 patients (83.5 percent). Eleven cases (7.3 percent) required repeated surgery with the Fogarty catheter. The patients with muscle tenderness, paralysis, or ischemia lasting longer than 24 hours had worse results in relation to the preservation of the limb (p < 0.05). We conclude that patients who present lower limb embolisms, are in good clinical condition, and who do not have any necrosis in the limbs, have good outcomes as to limb preservation, along with low complication rates, after embolectomy with the Fogarty catheter. Limb preservation was significantly higher in patients who did not present muscle tenderness, and who had normal motor activity and a ischemia duration of less than 24 hours.

Adolescent↗

Reliability of upper and lower limb three-dimensional kinematics in children with hemiplegia.

The repeatability of both 3D kinematic measurements of arm movement during simple upper limb tasks and lower limb movement during gait analysis was evaluated in 10 children with hemiplegic cerebral palsy. All tasks were completed on two separate occasions, 1 week apart. The 3D lower limb gait analysis showed high levels of repeatability in the sagittal plane measures, with mean coefficient of multiple correlations (CMCs) greater than 0.92 between sessions. Transverse and frontal plane measures had mean CMCs greater than 0.7 between sessions. A 3D analysis of shoulder and elbow flexion/extension during the two functional tasks (hand to head and hand to mouth) was highly repeatable between sessions (mean CMCs, 0.87 to 0.95). Rotational measures at the shoulder and the elbow during the same tasks demonstrated moderate levels of inter-sessional repeatability (mean CMCs shoulder 0.49 to 0.63; elbow 0.63 to 0.74). Overall, the lower limb 3D kinematic analysis had similar levels of repeatability in both the hemiplegic limb and the limb with normal tone. The 3D kinematic analysis of movement of the hemiplegic upper limb during simple upper limb tasks also had moderate to good repeatability, suggesting it may be able to be used as an outcome measure in the hemiplegic upper limb.

Adolescent↗

Reorganization of gait after limb-saving surgery of the lower limb.

OBJECTIVE: In this study, the concept of a cognitive dual-task performance and visual restriction during walking has been used to study the recovery of gait after limb-saving surgery in ten patients. DESIGN: All patients were recovering from some form of treatment to tumors of the lower limbs. Patients had to walk on a treadmill at their preferred speed. During the course of recovery, we measured normal walking, walking while performing an attention-demanding dual task, and walking during restricted vision, starting 5 mo postoperatively. RESULTS: Patients are able to reach an acceptable level of gait within 15 mo, especially when the basic locomotor activity (i.e., step-cycle duration, walking speed, gait symmetry) is taken into account. Nevertheless, the results showed that during the recovery, the patients were still hindered by the dual task and visual restriction while walking because they exhibited a decrease in step-cycle duration under these conditions. CONCLUSIONS: In general, an improvement in walking speed and a decrease in asymmetry was seen. On the other hand, patients still had a basically reduced control of gait after the 15-mo recovery period. This can be attributed to a lack of gait automatism caused by an irreversible loss of somatosensory input.

Adult↗

Ultrasonic systolic blood pressure gradient between upper and lower limbs in normal term Chinese neonates.

The determination of a normal pattern of systolic blood pressure (SBP) gradient between upper limbs (UL) and lower limbs (LL) in neonates is important in the diagnosis of the coarctation syndrome. The scarcity of studies of normal neonates and the conflict of opinion prompted us to evaluate this problem. The UL and LL systolic blood pressures of 100 normal term Chinese neonates were measured by the Doppler Ultrasonic method (Roche Arteriosonde 1020). Under resting condition, the majority (89%) of our neonates had a negative SBP gradient (LL greater than UL). The mean LL SBP (70.1 mmHg) was significantly higher than that of the UL (59.5 mmHg), p less than 0.001. Eleven out of 100 of our neonates had a positive (UL greater than LL) SBP gradient. Eight of these were less than 1 week old. None had a positive gradient of more than 20 mmHg. According to the results of our study, during the first week of life, normal neonates may have upper limb pressure greater than lower limb of up to 20 mmHg.

Blood Pressure↗

Relation between running injury and static lower limb alignment in recreational runners.

OBJECTIVES: To determine if measurements of static lower limb alignment are related to lower limb injury in recreational runners. METHODS: Static lower limb alignment was prospectively measured in 87 recreational runners. They were observed for the following six months for any running related musculoskeletal injuries of the lower limb. Injuries were defined according to six types: R1, R2, and R3 injuries caused a reduction in running mileage for one day, two to seven days, or more than seven days respectively; S1, S2, and S3 injuries caused stoppage of running for one day, two to seven days, or more than seven days respectively. RESULTS: At least one lower limb injury was suffered by 79% of the runners during the observation period. When the data for all runners were pooled, 95% confidence intervals calculated for the differences in the measurements of lower limb alignment between the injured and non-injured runners suggested that there were no differences. However, when only runners diagnosed with patellofemoral pain syndrome (n = 6) were compared with non-injured runners, differences were found in right ankle dorsiflexion (0.3 to 6.1), right knee genu varum (-0.9 to -0.3), and left forefoot varus (-0.5 to -0.4). CONCLUSIONS: In recreational runners, there is no evidence that static biomechanical alignment measurements of the lower limbs are related to lower limb injury except patellofemoral pain syndrome. However, the effect of static lower limb alignment may be injury specific.

Adult↗

Impact of risk factors on limb salvage after angioplasty in chronic critical lower limb ischemia. A prospective trial.

The impact of various general risk factors on long-term results of percutaneous transluminal angioplasty (PTA) in chronic critical lower limb ischemia is poorly known. In a prospective trial 209 PTAs were performed in 103 consecutive patients with 117 limbs with chronic critical ischemia. The general risk factors that might affect the long-term results of PTA in this patient population were reviewed. Among the factors that showed no statistical significance were all associated diseases, smoking history, and medication used. Of the various clinical chemical parameters, only serum high density lipoprotein (S-HDL) cholesterol and plasma fibrinogen had a statistically significant influence on limb salvage rate in Kaplan-Meier analysis. These parameters proved to be significant determinants also in Cox multiple regression analysis when PTA target-vessel-related parameters (peripheral runoff and number of diseased vessels) were also included in the model. Cox model predicts up to 86% one-year limb salvage for the "good" group (one to five diseased lower limb vessels/limb, S-HDL cholesterol > 0.78 mmol/L, plasma fibrinogen < 4.9 g/L).

Adult↗

A robust design procedure for improvement of quality of lower-limb prosthesis.

Lower-limb prostheses are used to restore amputee's walking. Monolimb is one of the designs referring to socket and the shank being molded into one piece of thermoplastic material. Appropriate shank flexibility of a monolimb can improve gait of an amputee. However, during the fabrication, the variations of design variables are inevitably produced which may lead the unexpected shank deflection and directly influence on gait efficiency of an amputee. This paper presents a robust design procedure for improvement of quality of the monolimb by simultaneously minimizing performance variations caused by variations in design variables and bringing the mean value of performance on target. The robust design procedure embodies the integration of response surface methodology with genetic algorithms. Response surface models are developed for the responses of monolimb as functions of design variables over the region of interest and genetic algorithms are employed to find the robust solution. A robust design of monolimb is performed for an amputee subject and the results show that the robust design can design a "robust" monolimb which provides specified performance targets that are minimally sensitive to the variations of design variables. This indicates that robust design may have the potential application in improving the quality of the prescribed prosthesis.

Algorithms↗