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Results for “Nevus, Pigmented”

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At least 55 records · Page 3Linked to original sources
PubMed1993

Subungual pigmented nevus: evaluation of DNA ploidy in six cases.

The discrimination between subungual pigmented nevus and subungual melanoma in situ is still a clinical problem. We measured DNA ploidy in six cases of subungual melanotic lesions which exhibited the features of subungual pigmented nevus or lentigo simplex histologically. Five cases presented a diploid pattern with or without a slight increase of hyperdiploid cells. One case presented a polyploid pattern; it also exhibited histologically abnormal melanocytes with large nuclei and pigment-filled elongated dendrites. The DNA ploidy pattern and histologic features suggest that the lesion of this latter case contains abnormal melanocytes which probably have the potential to undergo a malignant transformation into a subungual melanoma. DNA ploidy analysis, therefore, is likely to provide information for evaluating the biologic behavior of subungual melanotic lesions.

Adult↗
PubMed2006

Argon laser photoablation of conjunctival pigmented nevus.

PURPOSE: To evaluate the efficacy of an argon laser in the ablation of benign conjunctival pigmented nevi. DESIGN: Interventional case series. METHODS: We conducted argon laser ablations for conjunctival pigmented nevus in 30 eyes of 28 patients. Laser ablation was applied directly to the conjunctival pigmented nevus in all patients. All patients were followed up over a period of 12 months. RESULTS: In all patients, the conjunctival lesions to which the argon laser was applied disappeared almost completely within two days after treatment. No recurrence of lesions was detected in any patient during the follow-up period, nor were any conjunctival scars or conjunctival injections. CONCLUSIONS: The argon-laser ablation of conjunctival pigmented nevi uniformaly resulted in excellent clinical outcomes. Therefore, this study concludes that argon laser ablation is a safe and effective modality for the treatment of benign conjunctival nevi, and this method could replace the classical surgical procedure.

Adolescent↗
PubMedDate not supplied

Acquired leukoderma in congenital pigmented nevus associated with vitiligo-like depigmentation.

We report a 6-year-old boy who developed depigmentation within a congenital melanocytic nevus at the age of 3 years. During the following months a halo phenomenon and vitiligo-like lesions distant from the nevus appeared. A thorough search for malignant melanoma was negative. A second patient, a 45-year-old woman, had a large congenital nevus on the trunk with marked satellitosis. At the age of 20 years, partial regression of the large nevus occurred and, in addition, halos developed around almost all smaller nevi. Repeated searches for associated malignant melanoma were negative. We review the rare cases of halo congenital nevi and emphasize that depigmentation is not necessarily associated with malignant degeneration.

Child↗