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A practice-based randomised controlled trial of the efficacy of an electric and a manual toothbrush on gingival health in patients with fixed orthodontic appliances.

OBJECTIVES: The aim of the present study was to evaluate the efficacy of an electric toothbrush with a specially designed orthodontic brush head compared with a manual toothbrush in controlling plaque and gingivitis in patients with fixed orthodontic appliances over an 8-week period in a dental practice setting. METHODS: This was a randomised controlled, single blind, stratified, parallel group trial conducted in two specialist orthodontic dental practices by a specialist orthodontist. Group 1 comprised 41 subjects who used the electric toothbrush and Group 2 consisted of 43 subjects who brushed with a manual toothbrush around the orthodontic appliance for a timed 2 minutes twice daily for 8 weeks. Plaque around the fixed appliance attachments was measured using an orthodontic modification to the Silness and Loe plaque index, while gingival condition was scored using the gingival index and Eastman interdental bleeding index. RESULTS: There was baseline balance for all clinical variables (p > 0.05). Both groups had significantly less plaque after 8 weeks than at baseline (p < 0.001) but the group using the electric brush also had significantly less interdental gingival bleeding, as determined by the Eastman interdental bleeding index both at week 4 (p < 0.001) and week 8 (p = 0.004). The majority of subjects (n = 54, 64.3%) preferred the electric toothbrush. CONCLUSIONS: In conclusion, the results from this study would suggest that use of an electric toothbrush with an orthodontic brush head may be of benefit in promoting gingival health in fixed orthodontic appliance patients; however, the long-term effects (over at least 6 months) need to be evaluated.

Adolescent↗

Magnetic resonance imaging diagnosis of the temporomandibular joint in patients with orthodontic appliances.

OBJECTIVE: The purpose of this study was to investigate the accuracy of magnetic resonance imaging diagnosis of the temporomandibular joint in those with orthodontic appliances by comparing magnetic resonance images of the temporomandibular joints with and without orthodontic appliances. STUDY DESIGN: Magnetic resonance imaging was performed in a total of 20 temporomandibular joints before and after the insertion of 6 kinds of orthodontic appliances (types 1-6), and the magnetic resonance images were compared. RESULTS: With respect to disk position, the diagnostic accuracy was 80%, 75%, 70%, 70%, 65%, and 60% in order from type 1 through type 6. The distribution of stages for the assessment of condylar configurations was 80%, 55%, 40%, 40%, 20%, and 10% in order from type 1 through type 6. No significant changes were found in the condylar head marrow signals. CONCLUSION: Magnetic resonance imaging is performed in orthodontic patients preferably by using ceramic brackets in the front teeth and direct bonding tubes in the molar teeth while removing arch wires.

Adult↗

Effect of orthodontic appliance reactivation during the period of peak expansion in the osteoclast population.

BACKGROUND: Delays in the appearance ofosteoclasts at compression sites occur following orthodontic appliance reactivation when this is done during the period of osteoclast recruitment. This study examined changes in alveolar bone after appliance reactivation at a time coinciding with the peak expansion of the osteoclast population following the first appliance activation. METHODS: Orthodontic appliances were activated with 40 g on maxillary molars followed by a reactivation with the same force after 4 days in one group and sham reactivation in the other. Rats were killed at 0, 1, 3, 6, and 10 days thereafter. Orthodontic movement was measured cephalometrically. TRAP and interleukin-1 alpha (IL-1alpha) were measured biochemically, and changes in osteoclasts and root resorption were assessed at both compression and tension sites histomorphometrically. RESULTS: Teeth in the reactivated group displayed more initial displacement than controls but no more tooth movement 10 days following appliance reactivation. Also, increases in osteoclast numbers and surface percent, as well as alveolar bone Tartrate-resistant acid phosphatase (TRAP), became evident in the treated animals only 10 days after reactivation. However, IL-1alpha was elevated in alveolar bone within 1 hr following appliance reactivation but returned to baseline by day 1. There were no treatment-related difference in nuclear number per osteoclast or trabecular surface per osteoclast. Significant treatment-related increases in root resorption were evident at compression sites by day 10. CONCLUSIONS: These findings indicate that after appliance reactivation during the height of osteoclastic stimulation, a second cohort of osteoclasts can be recruited, but only after a delay of several days. This delay is not due to a failure to produce IL-1alpha in the tissues.

Acid Phosphatase↗

[The changes of subgingival microbials during periodontal maintenance in patients with gingivitic and wearing fixed orthodontic appliances].

OBJECTIVE: To investigate the microbiological changes of subgingival microbials in patients with gingivitis and wearing fixed orthodontic appliances. METHODS: 48 subjects (10 to 17 years old) with gingivitis, and wearing fixed orthodontic appliances, were divided randomly into three groups (placebo, NS and CH). Placebo group had normal saline mouthrinse; only and no oral hygiene instruction (OHI). The NS group had OHI and normal saline mouthrinse; The CH group had OHI and 0.12% chlorhexidine gluconate mouthrinse. Bacterial examinations were carried out on baseline, one week, one month and three months after scaling. The bacterial examination was carried out. The percentage of coccus, bacillus and spirochete was calculated. RESULTS: In placebo group and NS group, the percentage of coccus increased up to the third examination then dropped down. The spirochete's percentage changed inversely. CH group maintained an increasing trend in coccus' percentage and decreasing trend in spirochete's percentage. The percentage changes of coccus and bacillus between placebo group and CH group are statistically significant (P < 0.05). CONCLUSIONS: During the three-month examination, the CH group had better microbiologic change than the other two groups.

Adolescent↗

Antimicrobial effectiveness of a highly concentrated chlorhexidine varnish treatment in teenagers with fixed orthodontic appliances.

OBJECTIVE: To evaluate the recolonization pattern of Mutans streptococci (ms) on densely colonized teeth with fixed orthodontic appliances after treatment with a highly concentrated (36%) chlorhexidine varnish. MATERIALS AND METHODS: Healthy subjects (n = 19) with fixed orthodontic appliances and high bacterial ms counts in saliva were recruited. In order to establish a baseline registration, plaque adjacent to brackets was sampled and cultivated on Dentocult strips. Following professional tooth cleaning, chlorhexidine varnish was applied on all teeth for 8 minutes. The degree of recolonization with ms was assessed 2 weeks after varnish application in plaque around the brackets. For statistical analysis, the data were subjected to a repeated measures design. RESULTS: After 2 weeks, ms counts were reduced as compared to baseline values. However, the reduction only weakly met statistical significance (P = .049). CONCLUSIONS: The application of a highly concentrated chlorhexidine varnish in patients with fixed orthodontic appliances does not result in a distinct reduction of ms numbers 2 weeks after treatment.

Adolescent↗

Biodegradation of orthodontic appliances. Part II. Changes in the blood level of nickel.

The purpose of this study is to determine whether orthodontic patients accumulate measurable concentrations of nickel in their blood during their initial course of orthodontic therapy. Blood samples were collected at three different time periods: before the placement of orthodontic appliances, 2 months after their placement, and 4 to 5 months after their placement. The study involved 31 subjects, 18 females and 13 males, who had malocclusions that required the use of a fully banded and bonded edgewise appliance. The age of the subjects in the study ranged between 12 and 38 years. The blood samples were frozen and shipped to a commercial medical laboratory for analysis by atomic absorption spectrophotometry. The three blood samples for each patient were analyzed in succession on the same day to eliminate equipment variance that could occur if blood samples were analyzed on separate days. A total of 93 blood samples were sent for analysis. From the findings in this study the following can be concluded: (1) Patients with fully banded and bonded orthodontic appliances did not show either a significant or consistent increase in nickel blood levels during the first 4 to 5 months of orthodontic therapy. (2) Orthodontic therapy using appliances made of alloys containing nickel-titanium did not result in a significant or consistent increase in the blood levels of nickel. The results obtained from both parts of this investigation indicate that orthodontic appliances used, in their "as-received" condition, corrode in the oral environment releasing both nickel and chromium, in amounts significantly below the average dietary intake.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

A comparison of the periodontal health of patients during treatment with the Invisalign system and with fixed orthodontic appliances.

OBJECTIVE: Evaluation of the periodontal health in patients during treatment with either fixed orthodontic appliances or the Invisalign system. STUDY DESIGN: The study was designed as a concomitant trial. The evaluation of the patients started in February 2002 and was completed in August 2003. PATIENTS AND METHODS: Thirty consecutive patients each with fixed orthodontic appliances and with aligners were examined at three consecutive control visits for their periodontal condition. All individuals were part of the clientele of the Department of Orthodontics and Dentofacial Orthopedics of the Charité Berlin. The parameters evaluated were the modified Gingival Index, modified Plaque Index, modified Papillary Bleeding Index, and sulcus probing depth. The first three indices were recorded alternatively buccally and lingually in all permanent teeth from central incisor to first molar: buccally in the maxillary right and the mandibular left quadrants, lingually in the maxillary left and mandibular right quadrants. The sulcus depth was measured in four areas: mesially and distally, lingually and buccally in the 1st molar and the 1st premolar of each quadrant. Each control visit was concluded with a detailed, individualized oral hygiene instruction. RESULTS: The modified Plaque Index was significantly lower in the Invisalign group overall. On the other hand, the periodontal condition of the two samples was nearly identical. CONCLUSION: Periodontal health is not jeopardized, even though the Invisalign system aligners cover all the teeth and the keratinized gingiva in part. This could be attributed to the fact that aligners are removable and thus allow unimpeded oral hygiene.

Adolescent↗

In vivo study on metal release from fixed orthodontic appliances and DNA damage in oral mucosa cells.

Interest in the amount of metal ion intake from dental alloys has grown. Fixed orthodontic appliances usually include brackets, bands, and archwires made of stainless steel, nickel-titanium, or nickel-cobalt alloys, and these can release metal ions. The purpose of this study was to investigate the biocompatibility in vivo of fixed orthodontic appliances, evaluating the presence of metal ions in oral mucosa cells, their cytotoxicity, and their possible genotoxic effects. Mucosa samples were collected by gentle brushing of the internal part of the right and left cheeks of 55 orthodontic patients and 30 control subjects who were not receiving orthodontic treatment. The cells were immediately prepared for cell viability and the comet assay. Nickel and cobalt cellular content was quantified by inductively coupled plasma mass spectrometry (ICP-MS). The results indicate that nickel and cobalt concentrations were 3.4-fold and 2.8-fold higher, respectively, in the patients than in the controls; cellular viability was significantly lower in the patients than in the controls, and there was a significant negative correlation with metal levels. The biologic effects, evaluated by alkaline comet assay, indicated that both metals induced DNA damage (more cells with comets and apoptotic cells). There were significant positive correlations between (1) cobalt levels and the number of comets and apoptotic cells, (2) nickel levels and number of comet cells, and (3) cobalt levels and comet tails. This study corroborates that nickel and cobalt released from fixed orthodontic appliances can induce DNA damage in oral mucosa cells.

Adolescent↗

A review of orthodontic appliance problems in general dental practice.

Patients will often visit their general dental practitioner when experiencing problems with orthodontic appliances, even if they were referred to a specialist for treatment. Reassurance may be all that is necessary, but simple intervention may allow the treatment to continue with a minimum of interruption. This article is an overview of the common orthodontic appliance problems that may be encountered and provides practical advice on how to deal with them.

Equipment Failure↗

[Clinical analysis of PLI, GI and SBI in patients with fixed orthodontic appliances].

PURPOSE: The aim of the present study was to carry out a detailed analysis of the data on PLI, GI, SBI in fixed orthodontic patients. METHODS: 375 middle school students aged 12 to 15 years old were selected as control group, including 196 boys and 179 girls. 331 patients with fixed orthodontic appliances aged 12 -15 years from city were used as experimental group, including 101 boys and 230 girls without mouth-breathing. Gingival index (GI), sulcus bleeding index (SBI), and plaque index (PLI) were recorded for each individual patient six months after being with orthodontic appliances. Four upper and four lower incisors were assessed, the data of the two groups were analyzed with SPSS 10.0 software package for Student's t test. RESULTS: It was found that there were significant higher PLI, GI and SBI values in orthodontic treated patients (P<0.01). Although there was no significantly difference in PLI value between boys and girls (P>0.05) in the experimental group, there were statistically significant higher GI and SBI values compared boys with girls (P<0.01). There were significantly higher PLI and GI values in boys' lower incisor(P<0.01). Oral health care was difficult in patients with fixed orthodontic appliances. Boys' oral hygiene was poorer than girls'. CONCLUSION: In order to maintain periodontal health, it is very important to strengthen oral hygiene to children who receive fixed appliance, especially in boys, as well as control the level of plaque accumulation in the lower incisors.

Adolescent↗

Nickel and chromium levels in the saliva and serum of patients with fixed orthodontic appliances.

The aim of this study was to evaluate the concentrations of nickel and chromium ions in salivary and serum samples from patients treated with fixed orthodontic appliances. A second aim of this study was to determine any significant changes in these concentrations during any period of the treatment time. Saliva and blood samples were collected from 100 patients ranging in age from 12 to 33 years. Twenty samples from each group were obtained. The groups were as follows: In the first group, saliva and blood samples were collected before insertion of the fixed appliances. In the second, third, fourth, and fifth groups, samples were collected at 1 week, 1 month, 1 year, and 2 years after appliance insertion. The serum was prepared by centrifuging the blood samples at 3000 rpm for 10 minutes. The fixed appliances consisted of an average of 4 bands and 20 bonded brackets. No palatal or lingual appliances welded to bands or extraoral auxiliary appliances were used. The spectrophotometric determinations were carried out using electrothermal atomic absorption spectrophotometry. The results indicated certain differences in the amounts of nickel and chromium released from fixed orthodontic appliances during different periods of treatment. The Mann-Whitney U-test from the SPSS statistics program was used to analyze the significance of the differences between no-appliance samples and those obtained with the appliances present. In the serum, there were statistically significant increases in ion concentration in the second-year groups. In saliva samples, nickel and chromium reached their highest levels in the first month and decreased to their initial level in the rest of the groups. It can be concluded that fixed orthodontic appliances release measurable amount of nickel and chromium when placed in the mouth, but this increase doesn't reach toxic levels for nickel and chromium in the saliva and serum.

Adolescent↗

Nickel in dental plaque and saliva in patients with and without orthodontic appliances.

The aim of this study was to compare the content of nickel in the saliva and dental biofilm in young patients with and without orthodontic appliances. The possible influence of a dietary intake of nickel on recorded nickel levels was examined. Nickel content in unstimulated whole saliva and in dental plaque of 24 boys and girls (mean age 14.8 years) with intraoral fixed orthodontic appliances was compared with 24 adolescents without such an appliance. Sample collection was set up to exclude nickel contamination. Diet intake was recorded for the preceding 48 hours to account for the influence of recent nickel content in food. Saliva and plaque were analysed for nickel content using an electrothermal atomic absorption spectrometric (ETAAS) method. The acidified saliva samples were analysed as Millipore-filtered saliva with filter-retained fractions and plaque following dissolution in acids. No significant difference in nickel content of filtered saliva was found between the test and the control samples (P = 0.607); the median values of nickel content were 0.005 and 0.004 mug/g saliva, respectively. On the other hand, a significant difference was found for the filter-retained fraction (P = 0.008); median values for nickel were 25.3 and 14.9 mug/g, respectively. A significant difference in nickel content between test and control samples was also found in plaque collected at various tooth sites (P = 0.001; median values 1.03 and 0.45 mug/g, respectively). A stronger difference was found when comparing plaque collected from metal-covered tooth surfaces than from enamel surfaces of orthodontic patients. No association could be found between calculated dietary intake of nickel and recorded nickel in the test and control samples. It is concluded that nickel release occurs into the dental plaque and components of saliva of orthodontic patients, a situation that may reflect time dependence of its release from orthodontic appliances into the oral cavity and an aggregation of nickel at plaque sites.

Adolescent↗

Indications for the use of fixed and removable orthodontic appliances.

This article reviews the factors involved in choosing the type of fixed and removable orthodontic appliance therapy. While this cannot replace the essential hands-on experience from an undergraduate course or regional hospital unit, it provides a useful update and outline.

Humans↗

Nickel and iron in saliva of patients with fixed orthodontic appliances.

Saliva was obtained from patients receiving treatment with fixed orthodontic appliances. One saliva sample was taken without appliances, and another at least 3 weeks after placement. In some patients samples were also taken immediately after insertion of the appliance. Nickel and iron were quantified by electrothermal atomic absorption spectroscopy. There was a large scatter in the results. No statistically significant differences were found either in the concentrations or in absolute masses of nickel or iron in samples taken without appliances and in those obtained when the appliances had been in the mouth for at least 3 weeks. For samples taken immediately after placement of the appliance, there was a significant increase in both concentrations and masses of nickel and iron. It thus seems that there is a high initial release of metals, and the effect diminishes with time.

Adolescent↗