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PubMed1981

Pasteurella infections in respiratory diseases of young cattle.

Bacteriological examinations performed on 545 extracts of pneumonia-affected lungs and on nasal secretions collected from pneumopathy diseased young cattle led to the isolation of 176 (32.2%) Pasteurella (p.) multocida strains and of 125 (22.9%) P. haemolytica strains. P. multocida was isolated in 46.2% of the lung lesions and in 22.5% of the nasal secretions, P. haemolytica in 26.6% and 20.3%, respectively. Pathogenicity in mice was detected in 81.9% of the P. multocida strains and in 19% of the P. haemolytica strains. Pasteurella strains were very susceptible to chloramphenicol (82.3%), tetracycline (68%), penicillin (47%), and ampicillin and resistant to oxacillin, streptomycin and kanamycin. P. multocida and P. haemolytica strains in the respiratory tract and lung lesions of young cattle affected by pneumopathies represent the main ethiologic agent accounting for the clinical symptoms, anatomic lung lesions and finally for the death of the animal.

Animals↗
PubMed1975

[Morphogenesis and some problems of the pathogenesis of experimental Pasteurella infection in white mice].

The authors present materials on the study of the principal stages of morphogenesis of experimental pasteurellosis infection in albino mice in subcutaneous, intraperitoneal and intranasal infection. Particular attention was paid to the interrelations in the organism between the cells realizing the protective functions and the causative agent. It was established that the highly-virulent P. multocida strain was capable of intracellular reproduciton in the cells of the macrophage type. It was demonstrated that the protective course of infection was largely determined by its high rate of reproduction and its capacity to paralyze the protective function of leukocytes.

Animals↗
PubMed1984

Oral absorption of chlortetracycline in turkeys: influence of citric acid and Pasteurella multocida infection.

Plasma and tissue concentrations, following the oral administration of the antibiotic chlortetracycline (CTC) alone or with citric acid, were determined in healthy and infected (Pasteurella multocida) turkeys. The principal results were: 1) The dose (of CTC) versus plasma level relationship was nearly linear. 2) Addition of citric acid to an oral preparation produced significantly higher plasma levels when divalent cations Ca2+ (.3 g/liter) and Mg2+ (.1 g/liter) were present in the drinking water and dosage solution than when citric acid was omitted. 3) The concentration of CTC was considerably higher in the liver and kidney than in the muscle and brain. 4) Birds infected with P. multocida had significantly higher plasma levels than healthy birds. 5) Oral administration of CTC increased the survival rate of the birds infected with P. multocida.

Administration, Oral↗
PubMed1999

[Bacteremia and Pasteurella multocida pneumonia revealing HIV infection].

Pasteurella multocida is a major pathogen in local wound infections due to animal bites. Pneumonia and bacteremia are less frequent and usually associated with local or general impairment of host defenses. Scarce reports exist about Pasteurella multocida infections in HIV infected patients. We report here a case of hypoxemic pneumonia and bacteremia due to Pasteurella multocida revealing an HIV infection in a young man.

Adult↗
PubMedDate not supplied

Immunization of White Pekin ducklings against Pasteurella anatipestifer infection.

Since Pasteurella anatipestifer (PA) serotypes 1, 2, and 5 gave no significant protection against heterologous serotype challenge, a trivalent formalin-inactivated bacterin containing all these serotype cells was developed and tested in the laboratory. Two inoculations of bacterin in White Pekin ducklings at 10 and 17 days of age gave highly significant protection against challenge with virulent organisms. The protection lasted only 2 weeks after the second inoculation. A third bacterin inoculation given at 31 days or exposure to an active field infection during the period of protection extended protection to market age (7 wk). Aluminum-hydroxide-gel-adsorbed bacterin gave no better protection than bacterin without adjuvant. One inoculation of multiple oil-emulsion (MOE) bacterin gave absolute protection up to market age: unfortunately, it produced noticeable tissue reactions at the site of inoculation. Day-old ducklings were also responsive to PA bacterin, and developed significant immunity against experimental challenge.

Aluminum Hydroxide↗
PubMed1990

Pasteurella multocida: a rare case of shunt infection.

Pasteurella multocida, the major pathogen following an animal bite, is a rare cause of intracranial infection. This report documents the first case of ventriculo-peritoneal shunt infection with Pasteurella multocida.

Adult↗
PubMed1980

[Pasteurella multocida infections in birds following cat bites (author's transl)].

Infection with Pasteurella multocida caused by bites has been known for several decades. Cats are an important factor in Pasteurella multocida infection. Considerable numbers of victims are 'rescued' from the mouths of cats and submitted to bird reception centres for treatment. A number of bird shelters sent birds in this condition to the present authors for closer examination. The majority of birds caught by cats die. The mortality rates in shelters were reported to be 30, 90, 99 and one hundred per cent. Of the birds rescued alive from the mouths of cats, approximately 40 per cent died from the direct effects of the bites, and approximately 60 per cent died from Pasteurella multocida infection.

Animals↗
PubMed1992

Pasteurella multocida infection of a total hip arthroplasty. A case report.

The authors report a case history of a diabetic woman requiring revision hip arthroplasty of a Charnley total hip prosthesis that was infected with Pasteurella multocida. The infection of the loose prosthesis followed a cat bite to the same leg. Advice is given on the management of patients with infection following animal inoculations, and the subject of increased risk with a loose prosthesis is discussed.

Animals↗
PubMed1963

PASTEURELLA SEPTICA INFECTIONS IN HUMANS.

Five instances of infection by Pasteurella septica, an organism which closely resembles H. influenzae on methods of presumptive bacteriology, are reported from an acute treatment general hospital practice over a period of three months. This infection decidedly outnumbers those caused by other Pasteurella species in North America. The organism is apt to be identified as H. influenzae, Friedlander's bacillus or Mima polymorpha. Unlike these, it shows extreme sensitivity to penicillin, sometimes combined with resistance to antibiotics that inhibit or kill these other organisms.While in the past Pasteurella septica infection was considered to be characterized by persistent local infection following domestic animal scratches or bites, it is clear that it is more often found in cases of respiratory tract infection and peripheral septic disease. In three of the five cases reported, exposure to animals was the source of infection.Because mixed infection with confusingly similar organisms may occur, lack of awareness of extreme penicillin sensitivity of Pasteurella septica may account for persistent failure of antibiotic therapy.

Animals↗