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At least 55 records · Page 3Linked to original sources
PubMed1995

The circadian rhythm in activity of the periodic acid Schiff reaction and of the Mg and Ca content in rat liver in relation to age and season of the year.

The experiments were carried out on male Wistar rats aged 6, 12 and 24 months, over the four seasons of the year. Analysis of the results obtained in all age groups disclosed that changes in activity of the p.a.S (periodic acid Schiff) reaction and in concentrations of Mg and Ca in the liver showed rhythmic oscillations with a period of 12 hours. The maximal p.a.S reaction activity and of Ca and Mg levels were generally found to coincide throughout all seasons and in all age groups. The rhythms of change in these parameters in 12- and 24-month-old rats showed a phase shift as compared to the 6-month-old animals.

Aging↗
PubMed2004

Neuroendocrine differentiation of periodic-acid Schiff and Alcian blue-negative signet-ring cell-like cells and tubular adenocarcinoma cells within a gastric cancer.

A case of a Borrmann type 2 advanced gastric cancer with endocrine differentiation is described. Histologically, the cancer was either composed of cells arranged in a tubular pattern or formed solid nests of various sizes. The tubular pattern was composed of a moderately differentiated tubular adenocarcinoma. The histology showed partial carcinoid tumor-like features. Cancer cells inside solid nests had a signet-ring cell-like appearance. Periodic-acid Schiff (PAS) staining was positive in the cytoplasm of a few of the cells found in the tubular pattern and in the mucus in some lumens and on the apical surface of cells in some lumens, but PAS did not stain cancer cells in the solid nests. Neither cancer cells nor mucus in the lumens were stained with alcian blue. All cancer cells were strongly positive for Grimelius silver stain, and most of the cancer cells stained positively for chromogranin A. Electron microscopic examination showed electron dense neuroendocrine granules in the cytoplasm of cancer cells. Cancer cells were stained positively for pancytokeratin, cytokeratin 8/18 and carcinoembryonic antigen. Muc 1 mucin glycoprotein staining was positive along the cell surfaces of cancer cells, but Muc 2, 5AC and 6 stainings were negative, although Muc 3 stained positively in the cytoplasm of a few cancer cells. The present case is a gastric tubular adenocarcinoma with Muc 1-positive, neutral- and acid mucin-negative signet-ring cell-like cells, which is associated with neuroendocrine differentiation.

Adenocarcinoma↗
PubMed1985

Amino acid periodicities and their structural implications for the evolutionarily conservative central domain of some silkmoth chorion proteins.

The central domain is an evolutionarily conservative region that is invariant in length in the A and Hc-A families of silkmoth chorion proteins. This domain shows strong sixfold periodicities for various amino acid residues, such as glycine and large non-polar residues. The periodicities and their phase relationships, together with the documented prevalence of beta-sheets and beta-turns in the chorion, strongly support a secondary structure model in which short (4-residue) beta-sheet strands alternate with beta-turns, forming a compact antiparallel, probably twisted beta-sheet. This structure should be important for the establishment of higher order structure in the chorion.

Amino Acid Sequence↗