CASE OF PNEUMATOSIS CYSTOIDES INTESTINALIS.
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Pneumatosis cystoides intestinalis is a rare condition characterized by gas-filled cysts in the submucosa and/or subserosa of the intestine. The authors present a case of Pneumatosis cystoides intestinalis occurring in a patient with pyloric stenosis by duodenal ulcer and report a wide review of the literature. They discuss the major areas of study in its etiology, histopathology, diagnosis and treatment.
We describe the first case of pneumatosis cystoides intestinalis in dermatomyositis (DM) of an adult. Our patient had been in remission of her DM for years when pneumatosis cystoides intestinalis occurred. Discovery of it was concomitant with that of interstitial lung disease. The overall course of pneumatosis cystoides intestinalis was benign. We discuss the mechanism of bowel and lung involvement and hypothesize that vasculitis could be the underlying process.
We describe a case of pneumatosis cystoides intestinalis with unusual localization and radiologic features. Barium enema showed multiple, rounded, submucosal masses, which were polypoid and airless and were localized to a 20 cm segment of the splenic flexure. There was no extraluminal gas on X-ray. Puncture of these formations via colonoscopic biopsy did not result in deflation of air. Surgical resection was performed and the classical features of pneumatosis cystoides intestinalis were found. Isolated splenic flexure involvement in conjunction with atherosclerotic cardiovascular disease may suggest that pneumatosis cystoides intestinalis is a reparative process after ischemic injury.
Two cases of pneumatosis cystoides intestinalis occurring in the bypassed small bowel following intestinal bypass are presented. These cases and the recent recording of four others in the literature indicate this may be a common association. Etiology of the pneumatosis is unknown, but it is probably related to fecal reflux into defunctionalized bowel with the attendant alteration of bacterial flora.
A case of pneumatosis cystoid intestinalis associated with duodenal ulcer and pyloric stenosis is reported. Review of literature revealed that, this is the first reported case in the Sudan and in Africa at large. The clinical presentation of this patient was confusing and it seems reasonable to consider pneumatosis in the differential diagnosis of pneumoperitonium associated with duodenal ulcer to avoid unnecessary laparotomy.
Pneumatosis cystoides intestinalis, an uncommon disease characterized by the presence of gaseous bubbles in bowel wall, is studied by a review of 919 cases of the world literature. The subserous cysts are more frequently found in the small bowel while the submucous localizations are predominant in the colonic wall. The disease, occurring more frequently in males than in females, is associated with several other lesions: pyloric stenosis and scleroderma for small bowel pneumatosis, chronic cardiopathies and dolichocolon for colonic localizations. Jejunoileal bypass for morbid obesity is an increasing iatrogenic cause. Diagnosis is based on radiology and endoscopy with biopsy but is not yet correctly done in many cases. The treatment is essentially medical.
Pneumatosis cystoides intestinalis (PCI) is an uncommon disease manifestation characterized by the presence of air in the bowel wall. It is a benign condition that often responds to conservative management; however, it may be a harbinger of end stage disease, particularly in progressive systemic sclerosis. The authors report a case of pneumatosis cystoides intestinalis in a patient with progressive systemic sclerosis in the setting of mixed connective tissue disease that responded to conservative treatment. They review the current literature on pneumatosis cystoides intestinalis, focusing on possible etiologies and potential therapies.
Authors present a case history of pneumatosis cystoides intestinalis with free intraperitoneal gas mimicking abdominal hollow organ perforation. The illness occurred in old immunocompromised man. The diagnosis was based on exploratory laparotomy and supported by abdominal x-ray and ultrasound.
Pneumatosis cystoides intestinalis (PCI) is a relatively rare, mostly benign, condition. We report a case of chemotherapy-induced PCI with free retro- and intraperitoneal gas in a 17-year-old man with acute lymphoblastic leukemia. Chest radiography and upright abdominal radiography showed free intra- and retroperitoneal gas; computed tomography demonstrated subserosal gas collections. Conservative treatment with oxygen, metronidazol, and parenteral alimentation was performed, and PCI resolved within 2 weeks.
BACKGROUND: Pneumatosis cystoides intestinalis (PCI) is usually a complication of digestive tract or respiratory tract diseases, but rare cases have been described in systemic diseases, mainly systemic sclerosis. CASE REPORTS: Three patients, one with temporal arteritis and two with polyarteritis nodosa (complicating rheumatoid arthritis in one case) were treated by prednisone. All three developed PCI, complicated in one case by a retropneumoperitoneum. Medical treatment led to a favorable outcome in all cases. DISCUSSION: Sixty-two cases of PCI have been reported in patients with various systemic diseases (systemic sclerosis, systemic lupus erythematosus, mixed connective tissue disease, dermatopolymyositis, polyarteritis nodosa, rheumatoid arthritis, Sjögren's syndrome, amyloidosis). Systemic sclerosis is the most frequent condition (45%). In the other cases, corticosteroid therapy or digestive tract vasculitis are the main causal factors. Outcome is usually favorable with medical treatment. Laparotomy is rarely needed.
Pneumatosis cystoides intestinalis (PCI) is a disease in which small gas-filled cysts appear in the intestinal wall. Four cases presented here demonstrate the diversity of the associated diseases. In two of the patients constipation probably played a role; in the third patient decreased colonic motility, elevated intestinal pressure and increased mucosal permeability in the context of enteritis treated with codeine was the underlying problem; in the fourth high protein feeding and bowel ischaemia was diagnosed. Various aetiologies are presented in the literature. There is no specific history and physical or laboratory findings do not help to diagnose PCI. Plain abdominal film, ultrasound, computer tomography, magnetic resonance imaging, barium contrast studies and/or endoscopy may be necessary for diagnosis. Therapy is based on enhancing partial oxygen pressure in the bowel wall. PCI usually runs a benign course.
Pneumatosis cystoides intestinalis (PCI) is an uncommon but important condition characterized by the presence of gas-filled cysts in the submucosa and subserosa of the gastrointestinal tract. PCI has been associated with several clinical settings. We report a case where PCI developed in a patient with known celiac disease. To our knowledge, this type of coincidence has been described in seven prior cases. Since PCI often results in pneumoperitoneum through rupture of the cysts, it is important to differentiate the benign form of pneumoperitoneum, in which no intervention is indicated, from the life-threatening form with intestinal infarction and/or perforation, in which immediate surgery is mandatory. Differentiating between them can be difficult; this explains the high rate of negative laparotomy, which, in the past, occurred in 27% of cases. By performing diagnostic laparoscopy, we were able to establish the diagnosis of PCI and exclude intestinal perforation or infarction, thus permitting the patient to avoid an unnecessary laparotomy. Although diagnostic laparoscopy is not routinely indicated as a diagnostic tool for the detection of PCI, it proved to be a safe and accurate method to differentiate between the benign form of PCI and the life-threatening form. Whenever this differentiation has to be made, we recommend that diagnostic laparoscopy be performed first rather than primary laparotomy. Herein, the laparoscopic features of PCI are described and the coincidence of PCI with celiac disease is reviewed.
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Spontaneous penumoperitoneum and pneumatosis cystoides intestinalis have been undescribed complications of celiac disease. In the case reported, small bowel gas cysts caused an obstructing intussusception. The etiology of the pneumatosis cystoides intestinalis is discussed.
Pneumatosis cystoides intestinalis involving the left side of the colon has been infrequently described. The condition was recognized 234 years ago when it was discovered in a cadaver. It was not until 1946, however, that a description of this lesion appeared in the radiological literature of North America. Pathologically, it is characterized by the presence of subserosal or submucosal cysts, varying from one millimetre to several centimetres in diameter. The complications of this process are pneumoperitoneum and intestinal obstruction. Three patients are described, the first of whom had partial bowel obstruction. Radiolucent gas-filled cysts along the bowel wall were observed on the radiographs. An additional radiological sign noted by the authors was fixation and elongation of the sigmoid colon with loss of pliability of the bowel wall which persisted on the evacuation film.
Two cases of pneumatosis cystoides coli are reported. The authors present an anatomic and physiopathologic review of the entity and give the list of etiologies with the worse prognosis. The radiologic signs are described and their contribution to an accurate diagnosis is stressed, as it may avoid useless surgical interventions.
It is rare for pneumatosis cystoides intestinalis to give rise to abdominal pain. We report a patient with signs and symptoms of a perforated viscous in whom abdominal exploration was negative, but in whom biopsy of various intraabdominal cystic structures revealed only pneumatosis cystoides intestinalis.