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[Suicidal tendencies in endogenous and organic depression in elderly patients].

Fifty patients with endogenous and age-related organic psychoses (10 with schizophrenia, 6 with maniac-depressive psychosis, 11 with involution psychoses, 18 with cerebral atherosclerosis, 5 with senile dementia) were under this investigation. Characteristic of these were distinct depressions with suicidal tendencies. Clinical features of depression and suicidal manifestations were closely linked to age-related influences. Irrespective of nosology, depressive constructs simplified in aging with melancholic-dysphoric affect getting more and more pronounced. Distinct hypochondriac and relation delusions evolved and the feeling of solitude increased. Suicidal intentions became simple and primitively stereotyped, suicidal preparedness fell and suicidal attempts acquired increasingly impulsive nature. Severity and acuity of depressive experiences and suicidal attempts did not enhance with age.

Age Factors↗

[Dynamics of the clinico-pathophysiologic characteristics of psychoses in old age under the influence of azafen].

A study of singular doses and subsequent maintenance therapy by azafen on the higher nervous activity of mental patients in presenile age (67 cases) revealed that its action depends upon the dosage of the preparation and the nosological syndrome. A depressive involutional psychoses can be controlled by azafen in doses up to 75 mg daily. By dosages of 25 mg azafen reduces or cessates completely the syndrome of changed consciousness due to disorders of brain circulation. An arrest of a depressive syndrome in manic-depressive psychosis in old age can be attained by an introduction of 150-200 mg of azafen daily.

Aged↗